PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  sleep apnea/EDS slight headache and nausea and no real benefit I also have depression, 3 wks after Psych upped my Lexapro, I became really sleepy, went for another sleep test with MLST, CPAP working fine but had a lot of limb movement, ruled out RLS but no mention of PLMD (Periodic Limb Movement Disorder) which I later found was linked to depression and taking SSRIs, as someone said some times docs just treat symptoms, I didn't need to "stay awake", I needed a good nights sleep! Lowered the lexapro (might stop it) and feel much better F 45 7 days
2/24/2009
 5  sleep apnea/EDS mild headaches, feeling of being very "caffeinated", softer stool I take 200 - 400mg a day, and have found this drug to be a life-saver. Without it, I would be sleeping all the time and barely able to function. Start off at a low dose and work your way upward until you find a dose that works for you (though I wouldn't recommend going beyond 400mg/day as it hasn't been proven to be that much more effective at 600mg/day than 400mg/day). F 22 1.5 years
2/17/2009
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 5  extreme tiredness & foggy thinking Weight loss...I've gone from a size 18 to a 12...gotta love that! Mild headaches that go away with an aspirin. Love this medicine! While there are days that are not as energetic as others, my worst day on Provigil is 100% better than my best day off of it. F 38 2 months
2/14/2009
 5  I have apnea, sleepy in afternoon I take only half a pill per day. If I take more sometimes I feel like my heart is racing a bit and mild light headedness; but not always. If I'm already tired I don't get that. I've been on this about six months now. I participated in a lab rat study of a new drug that does the same thing last year but that drug is not yet available so this was prescribed. I take half a pill per day most of the time, I have no problems sleeping and no side effects that I can discern. I have not had issues with low blood pressure (mine is a bit on the high side but not bad). If it gets to be late at night and I have a need to stay up all night I can take an additional whole pill and function the whole night with no problem and sleep as long as I need to the next day without any symptoms of racing heart or light headedness. This pill has been used since WWII to keep pilots functioning on long flights, there have been few reported issues but as folks have already pointed out there statistically will be a few that can't use it. I drink about one or two soda's a day (with caffeine) have not noticed any issues with that. I think this is a great drug and until that other comp F 44 6 months
2/4/2009
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 5  Daytime Sleepiness Cocaine like cerebral high without the desire to fiend. My brain felt too big, not a headache but mild annoyance. Excessive foot tapping. Too talkative. No hunger. This is the first medication I have ever been on other than antibiotics and pain pills for wisdom teeth. I have taken every street drug that I can think of but have never been addicted to anything. I have always been content with getting 6 hours of sleep in a day. I am an IT professional and spend most of my day tied to my chair. I have found over time that my brain shuts off when I lose interest in something. This could happen quite often in the 4-5 meetings I have a week and I would nod off like a junky especially in the afternoons. I read about Provigil from an IT forum and thought I should give it a try. My annual physcial was today and my doctor gave me a seven-day trial after I explained to him (honestly) my background. I took 100mg when I sat down in the meeting and have had a splendid productive day. The meeting would have been a total bore, but I felt alive and it almost took on a party atmosphere due to my infectious talking. I liked it...perhaps too much. I have ne M 32 1 days
1/27/2009
 3  Fatigue, Fibromyalgia Very little out of body feeling This is my only second day 200mg. Can anyone comment on taking this in morning and social drinking in evening. F 50 2 days
1/27/2009
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 5  To counter side effects of Cymbalta I take the maximum dosage,200 mg tablets X 2 daily. Only one, and I didn't realize it might be a side effect until I read other entries on this site: the VERY occasional front lobe headache that quickly goes away with asparin. The drug I have to take, Cymbalta, leaves me overwhelmingly sleepy. I literally couldn't function w/out Proviil. Recently, the Thurs. before the MLK birthday long weekend. I ran out and, through a snafu, couldn't refill untl Tues. I slept, off and on, both day and night, through the long weekend. M 63 86 months
1/25/2009
 4  energy and depression When I started Provigil I immediately felt such an increased level of happiness, excitement, and energy. I am a flight attendant and I used it when I had to get up extremely early for flights. For awhile it seemed to be the best thing since sliced bread but then I noticed that it was making me more agitated as the day went on as well. I would get irritated at things that normally I would have been cool and collected about. But the main problem I found was that it increased my depression tremendously when I would stop taking it for a few days. I take paxil as well. I did enjoy the feeling it gave me for several hours after I took it. really decreases your appetite. M 53 3 months
1/25/2009
 5  excessive daytime sleepiness, fatig Mild headaches, slight nausea, tense jaw, dry/swollen eyes with large doses Has been a godsend, but PLEASE - YOU people who have posted about getting a rash while on Provigil - TELL YOUR DOCTOR. In rare cases this rash can be a serious problem. It is not a panacea - taking it too regularly diminishes the effects; you can build up tolerance; I find if I drink even a little bit of alcohol it dulls me much faster than if not taking provigil. Make sure you drink lots of water, stretch out, relax your jaw. Try taking the smallest dose you need at the time, then increase if you have to. Like others, I find it has changed my life positively - can do more work, stay awake while driving or in presentations/meetings - GREAT for museums where you tend to get tired! M 63 6 years
1/22/2009
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 4  MS fatigue none so far I just started to take it about 4 days ago and so far i have to say that i havent had any side effects yet, actually i kind of like it i wake up in the morning an take it and i notice that i have more energy through out the day i even started to go for walks during my lunch i just hope that i dont have side effect later down the line for a long term use of it. F 30 4 days
1/22/2009
 5  Brain fog from Hypothyroidism Bit over caffinated of I take more than half a tablet. Find I only need half a tablet every other day or so. BRILLIANT! I can concentrate and focus on work and even learn and remember stuff. Previously I would stare at the same page over and over without getting anywhere. Have found long term memory has recovered more than short term but still much better. I'm much less depressed and can cope much better. Still early days but I'm so relieved. F 44 3 weeks
1/19/2009
 5  Narcolepsy The only negative side effect I’ve had with Provigil are very mild, occasional headaches, but they are easily taken care of with some Tylenol. The positive side effects though are amazing! I was diagnosed with narcolepsy in my early 20’s…I had always felt like I was more tired than other people but I realized there was something really wrong when (even though I was sleeping 9-10 hours a night) I feel asleep in the middle of an air shift at a local radio station that I was working at! But since starting the drug about 3 years ago I can only think of once or twice where I have fallen asleep inappropriately...miles better than the every few hours I was falling asleep before! Something else I’ve found interesting is that the longer I have taken it, coupled with trying to stay on a pretty consistent sleep schedule, my sleep quality seems like it has gotten better. I used to have a lot of very vivid dreams and hypnotic hallucinations but they seem to happen much less One thing I’ve noticed (and I think I remember reading this in an article somewhere) is that Ibuprofen seems to interact with Provigil. For me it seems like it might speed up the metabolism of it…I’m not sure, but I know that if I take an Ibuprofen just a few hours after taking a dose of Provigil I feel like I’ve taken too much Provigil…I get that kinda weird, kind of hyper/nervous feeling, and then I’ll ‘crash’ a few hours later and be very tired. But I’ve used this to my advantage too a few times…if I start getting tired in the late afternoon (I just take 200mg in the AM) if I take an Ibuprofen it’s almost like I’ve taken another dose of Provigil but it wears off in plenty of time for me to go to bed. This has not happened when I’ve taken Tylenol. F 25 3 years
1/18/2009
 2  hypersomnolence The first day was great. I felt like I had a new lease on life. Second day was okay but not as good as the first. On the third day I noticed a slight rash on my lower legs. On my inner thighs there was a large area that was red and chapped looking. These symptoms would wax and wane. And they would intensify if I took an extra 100mg to get me through the day. The symptoms never got unbearable. But very close. I only took it for one month since it was nowhere near as effective as I expected, cost was $380 (not covered by insurance), and gave this side effect. Now one month later, I still have the same symptoms. If it works for you, great. But it turned out to be more of a hassle than it was worth. M 30 28 days
1/15/2009
 2  Fatigue/Medicine side effects Sweating, less of an appetite, brain fog, couldn't make decisions, felt like I couldn't talk, couldn't focus. I was on 100mg in am and 100mg in pm. The first day I took this I felt great! I had energy and was productive and felt awake. I thought it was going to be a miracle drug. Ha! Everyday after the first was hell. I felt mildly awake but asleep at the same time. It made me like a zombie. My husband would laugh at me because it would take me way too long to make simple decisions. Stopped taking it a week later. Switched to Methylphenidate and had similar side effects. Now on Adderall and it's too early to tell if this will work yet. Hope so! F 31 6 days
1/15/2009
 3  ADD inattentive type Initially, insomnia, but as the positive effects wore off so did the insomnia. My anxiety levels probably increased too. I have anxiety to begin with. I should note that I was taking both Provigil and the generic form of it, Modalert. Provigil seemed a little brighter, but I noticed the same trend: good concentration for the first 6 or 7 times I took it and then less and less positive effects. After taking both forms of modafinil, I would become more irritable. M 43 3 months
1/2/2009
 5  sleeping too much maybe a little high but nothing else M 57 1 years
1/1/2009
 3  idiopathic hypersomnia headaches, backache, some jitters, some nausea, "weird" feeling. side effects seem to be reducing as time goes on. 400 mg in the AM. helps a bit with tiredness, seems to wear off after 6-8 hours and then I'm more tired than usual. with tweaking this drug may help for those with hypersomnia. M 46 7 days
12/28/2008
 5  Shift Work Sleep Disorder Mild frontal lobe headache, strange smelling urine, insomnia if taken too late in the day. very helpful if taken 1 hour before my shift as a nurse 11pm-7am. I do not take it on my days off. I LOVE this med. It has been a lifesaver for me as I have worked nights for the last 9 years. F 33 8 months
12/27/2008
 1  Severe Fatigue anxiety, sweating spells for hours, severe shaking, crying all the time, paranoia, depression, INCREASED fatigue, headache, nausea My doctor prescribed this because I was experiencing severe fatigue related to some medical problems I was having. The first time I took it I felt increased energy, a little on edge, but not bad. Second day and each subsequent day (I only took it 7 days), my side effects got worse and worse. I would lay on the couch for hours shaking and sweating. I was crying ALL the time. I got extremely depressed to the point I was planning my suicide. I was constantly nervous. Luckily I live with my parents (due to my health problems) and my Mom noticed the changes happening to me and got me off of it. By the time I stopped I was almost psychotic. As a side note, I have no history of mental or mood problems, so this was way out of the norm for me. It took two weeks to feel back to normal. Everyone reacts differently to medications, a lot of people love Provigil, it just did not react well with my body. F 31 1 weeks
12/18/2008
 5  Shift work None - it is great I started out with 200mg - WAY too much. 100mg is perfect - I stay alert and don't feel "spacy", which I can't afford in my line of work. I only take it when I work though, which is 7P-7A 3 times a week. An answer to my prayers..... F 32 3 months
12/16/2008

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