PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Chronic Fatigue Syndrome/Narcolepsy Headaches. Absolutely, positively MUST start with a low dose. IF you have a headache -- your dose is too high -- reduce your dose for awhile. With time, I was able to increase my dosage. F 55 1 years
4/29/2008
 3  ADHD, Predominantly Inattentive Typ First day smelly urine and slight palpatations I just added it to my personal cocktail that I take for bipolar ll and anxiety. The complete mix includes, seroquel,lithium lamictal, buspar and now provigil for recently diagnosed adult adhd passive. It has not triggered bipolar cycling nor have there been any drug intereaction issues. I have been able to read the New York Times several days this weeks but I still don't know how effective this will be in the long run. F 54 13 days
4/28/2008
 1  Excess sleepiness DO NOT TAKE THIS DRUG! SORRY ABOUT THE "SHOUTING" BY CAPITALIZING BUT THIS REPORT DESERVES IT. I SUFFERED HALLUCINATIONS DUE TO HYPOXIA (LOW OXYGEN TO THE BRAIN), CARDIOGENIC SHOCK, ACUTE KIDNEY FAILURE AND HEART FAILURE. I WAS IN A COMA FOR NEARLY 2 WEEKS. I AM VERY, VERY LUCKY TO BE ALIVE. READ THE NEW WARNINGS FOR THIS DRUG, REQUIRED BY THE FDA AFTER DEATHS CAUSED BY MUTIPLE ORGAN FAILURE SUCH AS WHAT I EXPERIENCED. IT ALL STARTS WITH LOW BLOOD PRESSURE. IF YOU TAKE PROVIGIL AND START FEELING DIZZY WHEN YOU GET UP OR WALK AROUND, YOU ARE IN SEVERE DANGER. CONTACT ME AT [email protected] IF YOU EXPEREINCE THESE SYMPTOMS. THIS DRUG MUST BE TAKEN OFF THE MARKET. M 54 3 months
4/20/2008
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 2  narcolepsy dry mouth, constant headaches, jaw clinching, foul smelling urine The first day I took this drug I was so excited because of the energy I felt. The next morning when I woke, took my medication with no reaction. Up the dosage and had the same result. Great energy the first day, then no increase in energy. The positive side though was how I had more clarity in my thinking. Even though I didn't have energy back I was willing to stay on the drug to keep the fog out of my brain. I was hopeful the side effects would eventually go away. Instead they got worse. I stopped taking the drug two days ago and I am really glad. It's nice not to wake up with a headache after clinching my teeth all night. Good luck to those who are having success and happy hunting to those of us that are still searching. F 45 2 months
4/18/2008
 4  MS fatigue rubbing my tounge against my teeth. Rapid thoughts This is my 2nd being prescribed Provigil. The first time around,I nearly drove my family crazy with my talking and myself crazy trying to keep my rapid toughts to myself. I dont know if the drug has change or if it is becasue I have gained weight but this time I am not having those problems. I take 1/2 a pill every few days and have been doing wonderful on it. I still took a nap yesterday even with taking it, but I am more productive and can actually do stuff with my kids! F 31 2 weeks
4/14/2008
 2  EDS Dry mouth, slow reaction time, poor concentration, excessive sleepiness. I swear this drug made me more tired than before. F 42 7 days
4/7/2008
 4  adult add-cognitive slowing ringing in ears- initial sleep problems but resolved now as I only take AM-difficulty achieving erection during effective period during the day but OK at night-increased overall sexual desire- desire to smoke to which I succumbed occasionally-initial weight loss but good now Very effective for me. Helps to stay focused and on task and I am much more alert. I am prescribed 500 mg but usually take around 300 and I find modulating dosage increases effectiveness, taking a day or two off or taking less. Only worry is long term dependence. I've never taken more than prescribed and have no desire to. Not addictive in traditional sense but seems unnatural somehow even though it seems helpful. Very expensive but I prefer not to use other stimulants. M 54 1 years
4/6/2008
 3  chronic pain & med narcolepsy dry mouth, headaches, strange smelling/dark coloured urine, clinch jaw, magnified pain,severe abdominal pain. All side effects are slowly reduced or gone. Chronic pain & medication induced narcolepsy 3 yrs. First 2 days great! 3rd day only helped keep on task and clearer mind. I take 100 first thing, 100 late morning. Dr said this was the max. I printed some responses from this site for him to read to challange him on that. Maybe with an increase dosage provigil will work for me. F 45 2 months
4/1/2008
 3  CFIDS, Fibro,Lupus,Sleep Disorders First few days uncomfortable chest pressure. Mild shortness of breath. Mild Hyperactivity. Short-term depression. No deep sleep. Burning eyes. Swollen itchy eyes. Loss of appetite. Mild flushed face (butterfly flush from cheeks over nose). To begin with, I have been struggling with severe fatigue lately. The first few days of Provigil, I started with 200mg and had mild discomfort in the chest with a little shortness of breath. I had also experienced the mild hyperness with moderate depression. I decreased the dosage to 100mg and continued to experience the mild hyperness with no deep sleep at all. The depression lifted but was replaced with itchy, watery eyes. Today woke up with a swollen, itchy eye and a mild flush of a butterly shape over my cheeks and nose. I love the extra lift this gave me in the day, but, at the expense of these side effects, I am afraid to take more. F 43 2 weeks
3/31/2008
 4  Depression I'm prescribed 200mg/day, sometimes take 100. Started w/ 50. Difficult getting to sleep. Wake up too early. But not much negative effect from less sleep. Groggy upon waking. Jittery only when taken w/ caffeine. Slight blurred vision. Increased sex drive. Easily distracted. interrupted long-term memory (can't remember names of things like "Provigil") increased talking. Smelly urine, but who cares? A little more irritable. This REALLY helped. I didn't realize how chronically depressed I was. 15 years ago I was involved in everything w/ lots of hobbies and active tasks. Always upbeat, never bored, positive outlook. Until I started taking this, I had lost interest in most things, not wanting to do much (age and marriage may have some effect here). Some euphoria early on, but that has mostly abated, some declining effect over time.. When I drop back to 100mg, it sort of "resets" the effectiveness. Increased sex drive may be from not being depressed. I am concerned of brain altering drugs and about potential of dementia and parkinson's because of dopamine altering. M 53 1.5 years
3/28/2008
 5  Shiftwork sleepiness I really haven't had any. I work for a 911 center and it is VITIAL to be alert when on midnight shift. I was finding that no matter how I tried to adapt my sleep during the day I was never rested enough to make it through the night. I could sleep soundly anywhere from 5 to 9 hrs and nothing was ever enough. I started taking it a few months back and it has been a life saver... in more ways then just my own. I am alert (not wired like on meds but like im rested and awake) and able to make it through my shifts with no problem. I found that taking a whole 200mg tablet was just too much for me. It would keep me awake WAY more then I wanted to be. So a half a pill at the start of my shifts is just enough to get me through fine. I have recommened this to alot of people that work shift work and everyone says it is a great drug. F 25 2 months
3/26/2008
 5  PTSD, Depression, Sleepiness None whatsoever, which is unusual for me. I have severe PTSD with major depression/difficulty sleeping. I tried many anti-depressants and all were in-effective and/or worsened my condition. I decided to focus on talk therapy and nutritional support but sleep loss due to nightmares, low energy, and afternoon sleepiness limited my progress. After research I tried Provigil. I take 100mg upon waking and have improved energy, focus, mood, and mental clarity. Despite suspicions I have found no side effects. I skip taking Provigil periodically to check for dependence and see none. The greatest benefit is that it aids in keeping me in a frame of mind where I can put forth the maximum effort in therapy while at the same time deal with everyday issues. I want to be the best husband and step-father I can be and Provigil has proven to be an important addition to the other steps I take to achieve my goals. I'm still squeamish about relying on a pill and would rather not, but I have a lot of work to do to improve who I am and the Pr M 51 1 years
3/26/2008
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 2  Narcolepsy Minor itchy red rash. It's a miracle drug. It works great but unfortunately with warnings from the FDA concerning life-threatening rashes I think I better discontinue and try to find another solution. M 30 2 days
3/24/2008
 5  chronic fatigue, cognitive slowness I had insane headaches the firs two weeks and kind of a fake flu, but it went away. I stayed on it because the change in energy and mental wakefulness was amazing. I went from getting a BS in chemistry to keeping my address written down and w/me at all times. The provigil let me go back to school. I've been on it for 7 years w/a few small breaks. It's amazing. I can totally feel the difference w/out it. It helps stabalize my appetite too. I'm going down on my dosage right now so wish me luck. I'd recommend it completely. Can't wait for the generic! When ready to have children ladies, please talk to your OBGYN. I don't think this is good stuff to be on during the first trimester. F 33 7 years
3/23/2008
 3  Fatigue/Daytime sleepiness 100 mg no side effects/did not work 200 mg no side effects/did not work Just started 400 mg, its been 4 days of living in a fog with mild headaches. I can't seem to focus on the task at hand. I'm not tired anymore during the day, but I have to be focused at work. Has anyone else have problems like this starting out? Feed back greatly appreciated. M 39 2 months
3/20/2008
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 3  excessive sleep, no focus or drive jaw clenching, teeth grinding, tongue biting, loss of appetite, excessive thirst, jittery, desire to feel my teeth with tongue, foul odor in dark urine, frequent urination, increased my OCD awareness, lasts too long for my liking, strange "come down" Helps me focus on getting school work done in large amounts. Great study tool for me because my depression, though treated with other medications, causes loss in focus and procrastination. I'd rather nap for hours. F 18 10 times
3/17/2008
 5  Finals week/full time job&school My body still feels moderately fatigued and I have occasional bouts of fogginess. I was sick to start out with and now my illness is much worse. My lungs burn and I have a terrible cough. I hardly have a voice left and I attribute the worsening of these sx's to the Provigil... or maybe sleep deprivation? Also, something strange has been going on with my throat. Swallowing has become rather difficult, but I'm pretty sure it's because of this bug I have. I'm taking it to keep me awake for unreasonable lengths of time, so I suppose to the average person, this side effect would be insomnia. I'm taking it because I am super sick, have three huge essays due and three finals this week on top of working 45hrs weekly.I haven't slept in 48 hours and I am pretty sure that I can last until 8pm tonight when class gets out. I just took my last 200mg tab. I was taking 200mg twice daily. Wish me luck- time to pump out my last 10page essay... F 23 3 days
3/13/2008
 1  iwork midnights it did not work i was taking 600 mg at a time and it does nothing M 28 6 months
3/11/2008
 5  CFS A bit of euphoria! This has been a wonderful med. Of the many I take I applaud this one for it's effectiveness and lack of side effects. I have taken as little as 50mg a day up to 100mg in two parts. I feel well rested and not artificially alert. F 51 3 years
3/8/2008
 5  daytime sleepiness(mild narcolepsy) jaw clench, smelly urine, have to watch combining it with caffeine, can't take it after say about noon, if I want to sleep I posted 10/05 in this forum. I am still on 300-400mg daily. Taking it 5-6 years. Stopped for 4 months (insurnce company), experienced vivid nightmares where I would wake up screaming. I wouldfall asleep for a milisecond and be yanked awake with such intensity I would wake up screaming. This cycle could be repeated several times at the start of a night. It was horrible. Get sleepy, fall asleep, wham scream wake, sleepy, sleep, wham scream wake. Some nights, I sat up watching tv until my body just gave out and slept. I found it fascinating that taking provigil for daytime sleepiness improved the quality (no nightmares,scremaming) of my sleep. The nightmares were in blazing technicolor and almost seemed real. Thenak god they are gone. I have found no addictive properties to it. F 48 6 years
3/7/2008

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