PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Depression Extremely bad headache during the first week, odd urine smell, irritability, strange dreams, wooshing feeling, numbness Side-effects are kind of sucky, but overall benefits are worth taking it. More energy, ability to concentrate, not overeating. Actually, I now get so engrossed in what I'm doing that I forget to stop and eat. M 35 1 months
6/27/2008
 5  Daytime sleepiness Strong urine smell. Occasional shortness of breath. Does the trick - miracle drug if you ask me. For years was diagnosed as depressed even though I did not feel depressed - Doctors assumed so due to excessive sleepiness. Sad that I didn't know about this years ago. F 40 4 months
6/25/2008
 5  obstructive sleep apnea/hypopnea Slight headache first day towards end of day on the first day, None on second day. Will post more info at the end of the week I have always been sleepy during the day since I was in High School, but I never would have guessed that my excessive sleepiness was caused from OSA. I was a pretty smart kid but I could never stay awake in class and would often wear a hat so the teacher couldn't tell i was sleeping. I ended up dropping out of college because I fell asleep in every class causing me to miss material and fail exams. Soon after began working full time in an office only to get fired for falling asleep at my desk. After attending a polysomnography test at a sleep center I was prescribed a CPAP machine for Obstructive Sleep Apnea (OSA) which helped but still have fell asleep during most days. My doctor prescribed me the 7 day trial so I'm testing it out. So far so good. Been really alert and have not dosed off once. Also, got a lot done today M 26 2 days
6/16/2008
 2  fatigue, brain fog, sleepiness headache first two days, loose bowels,a growing feeling of anxiety as medication wore off I'm a chronic insomniac and obviously that is the biggest reason for my tiredness, but I always feel spacey and can't concentrate so my psychiatrist suggested Provigil. I am also on Lexapro 20mg for depression. Upon taking the first 200mg pill on day one, I felt okay - slightly energized, then by 5pm I had a massive headache that went on into the night. The next day - feeling ill from no sleep and headache I cut it in half to 100mg and felt okay. On day 3 my lower back started aching, but no headache, day 4 today I had loose bowels and could feel the medication wearing off around 4pm - just a crashing feeling of tiredness, and feel a lump of anxiety in my stomach that I've not felt before. I may stick with the 100mg to see if things improve, but so far the side effects are not worth the few hours of energy/concentration. F 30 4 days
6/16/2008
 3  sleep apnea treatment ineffective colored urine Odd how a drug can make you both alert and asleep at the same time. Perhaps it merely wakes me up enough to observe how far south I have gone. Better than nothing for uncorrectable sleep apnea M 55 4 months
6/14/2008
 4  ADD The first couple of weeks I had trouble sleeping. I seem to be more prone to sinus problems. More sensitive to caffeine. I had problems at work and read up on ADD and read how so many others have the same problems. Saw a Psychiatrist and asked him about it. He ordered a QEEG and came to the conclusion I had low histamine levels and put me on Provigil. I take 200mg in the morning and 100-200 in the afternoon on workdays depending on how busy I am. I have forgotten it before on numerous occasions, each time I was reminded how well it works. Overall I can't see where I have had any major side effects, I have always been a little sensitive to caffeine and this has increased that a bit but overall so long as I keep that in check and there are no other outside factors keeping me from sleeping no problems. I have also moved on to a new job where I am doing great, I still have to work to stay organized and I make errors but overall my experience has been great. I was diagnosed with ADD at 28. M 30 2 years
6/13/2008
 2  Chronic Fatigue Syndrome I have OCD as well as CFS. 100 mg dose did nothing for me. So I went up to 200 mg. After two days, my OCD symptoms (which had been under control) were much worse. The next day, before taking the Provigil, I had a horrible panic attack. My heart was racing and I had trouble breathing. I felt like I might die. However, I knew I was having a panic attack and so was able to ride it through. I have discontinued use of Provigil. I would recommend serious consideration before taking Provigil if you have any form of anxiety disorder. I would also recommend discussing the medication with a psychiatrist (not just your regular doctor) before starting treatment. F 29 5 days
6/13/2008
 4  hypersomnia increased energy, increased drive to get things done, occasional naseua after taking it, can concentrate a lot better, strong good mood after taking it, sometimes jittery after taking it I have hypersomnia and ADD, and this drug helped with both. Definitely do not take this with caffeine. I am on 200 mg a day of Provigil, and I once made the mistake of taking it with a Diet Coke. I was supposed to drive 2 hours back from a trip I was on, and I was too shaky and jittery to get behind the wheel. F 22
6/11/2008
 5  Fatigue, Atypical Depression Slight GI upset in the evening. Moderate dull frontal lobe headache and would sometimes feel like it was behind my eyes; not treated with Acetaminophen, Ibuprofen or Naprosyn. I would endure a near migraine headache and still take this drug. It has completely changed my life and did so in the first hour. I wake up early, go to bed easily and best of all....stay asleep as I used to wake up 4-6 times a night. QUESTION? WHat have people done to treat these headaches? I have tried all the normal things along with caffeine and no luck. Your help is greatly appreciated. M 32 7 days
6/10/2008
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 3  Disrupted Sleep Patterns Extreme Nausea day 8. Non-stop ringing in the ears day 11 and beyond. Thought I had a brain tumor due to the ringing and vertigo that was actually the nausea. I am nap free, but spending my old nap time trying to fight the stomach pain and annoying ringing ARG F 38 19 days
6/10/2008
 5  MS related fatigue Strong smelling first morning urine, racing thoughts, sometimes socially inappropriate comments I take 200mg twice a day. My life would be a mess (spent dragging around or sleeping) without this drug. I can have a day that is productive; my mind focuses better, and my speech is not choppy. I am just more "me". F 53 5 years
6/9/2008
 4  Chronic Fatigue Syndrome rapid thoughts, stong urine odor, difficult to go to sleep at night This drug is effective. I can think clearly, and it gives me the energy to accomplish tasks. I can focus on what needs to be done and not just lie around all day watching TV, wishing I had the energy to get up and go. I never take it after 12 noon, or it will not wear off in time for me to sleep. I do not take it every day, perhaps three times a week. But I need it everyday, just don't want to become resistant to its effectiveness. F 48 2 years
6/9/2008
 5  Fatigue/Eppstein-Barr Virus Increased energy, excellent concentration, appetite suppressed, clear mind, organized thoughts, more alert, overall feeling much better and more normal. After 15 years of doctors switching me from every antidepressant on the market, I demanded that they check into Chronic Fatigue Syndrome and allow me to at least try Provigil to see if it helped me. My doctor did some blood work and I left the office with a prescription for Provigil 200 mg. daily. I took my first dose, and in less than two hours, I was a new person. This IS my miracle drug and I feel normal again. Eppstein-Barr affects people differently and usually shows no signs. 95% of adults over 30 in the United States have this virus (contracted from being exposed or around someone with Mononucleosis during childhood or adulthood). Still taking 200 mg every morning. I forgot to take it one day and could not stay awake and could not stop eating, just like prior to starting Provigil. F 35 6 months
5/30/2008
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 3  Narcolepsy & Chronic Fatigue Strange sense of impending doom, anger & anxiety, headache, bad smelling urine, post nasal drip, fuzzy vision, muscle aches, and decreased appetite. This is my second time trying provigil. I am only taking 100 mg per day because I cannot handle the full 200mg. The first time I took it, I did not have the headaches, smelly urine, post nasal drip, fuzzy vision, or muscle aches. A word of advice is to make sure you eat while taking provigil. You will probably lose your appetite. When I was taking it regularly, I barely ate and went through rapid weight loss. Not eating enough calories screwed up my metabolism, so when I stopped taking the provigil, I rapidly gained all my weight back + 2 lbs and have not been able to lose the weight through exercise. (I took provigil for a duration of 1 year) F 27 5 days
5/29/2008
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 4  EDS due to OSA, fatigue due to meds First week some stomach discomfort, headaches but these went away after splitting my dose 100mg 2x day and taking with food. I feel truly functional for the 1st time in years. Each person reacts differently to meds. I've read every pamphlet/website/research study re: Provigil that I could find. There's risks with any meds and I'm willing to take them w/Provigil to get my life back. I log all side effects so that I have a record of how my body is reacting to the med and can discuss w/my Dr. if necessary. I'm very grateful for Provigil. It's worth it. F 39 1 months
5/28/2008
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 4  Multiple Sclerosis Fatigue & OSA Extremely Dry Mouth, Loose stools,stomach cramps, and butterfly shaped flush on my face like some others have said. This medication has raised my blood pressue ALOT ! Working with MD to find a combo of BP meds to allow me to keep taking this medication. I have been battling MS Fatigue to the point of almost thinking of quitting my job, but desparatly need the money. I can complete all tasks just like before diagnosis of MS. It is a little pricey even with insurance. Trouble convinving insurance co. to pay for it and MD had to call them herself. Had to cut the dose down from 200mg to 100mg sometimes 50 mg because I could not wind down for sleeping. Overall, I think I will keep taking it. F 33 4 months
5/27/2008
 5  Fibromyalgia and extreme fatigue Alertness, felt normal for a change, energy level high - first time i took it could not get to sleep, so I take it earlier in the day 200 mg. can't take it daily - have to skip a day here and there. Extreme dry mouth and painful tongue, small price to pay for normal. Like others, I forgot what normal felt like - love this med, but can't take it all the time; about 3 days and then off for a few or it will "backfire' and I will be exhausted - sleep for 15 hours straight. I couldn't believe the difference it made - me, who would never take even an aspirin! F 54 8 months
5/24/2008
 1  Stroke related sleep apnea Hallucinations, extreme sleeplessness, restless, overactive imagination This was prescribed for my aged father after a stroke - to "pump him up" for rehab, etc. This med caused hallucinations, repeatedly, and caused him to lose sleep and his imaginaton was "out of this world." As we began to wean him off this med, he could not sleep at all, for days on end. After the med was out of his system, the hallucinations and restless subsided or went away completely. M 77 2 months
5/23/2008
 1  Sleep Apnea Dry mouth, loss of appitite.Dizsy every time I got up. Bad headaches Started taking the drug on tuesday and by Thursday. I could not move at any time without the room spinning. It got so bad that I colapsed at work and had to go to ER. I was not able to talk and my jaw became heavy and swollen. After only three days it had this effect. It is a very dangerous drug! F 33 3 days
5/5/2008
 1  Sleep Apnea, effected performance At first, none. About 3 - 4 months in, numbing and tingling of extremeties, toes, esp fingers. Did not see that as a side effect listed? Took 100mg in AM and 100mg after lunch. A week ago 4/24, extreme high fever (thought it was the flu...stopped the Provigil to take night OTC cold meds, thinking it was the flu...) NO congestion though, never had flu been like this?? In two days 4/26, fever had subsided, however, body parts ached like crazy. I went back on Provigil 4/26 not thinking that it could be from it...Sunday, feeling better, but dilerious, not all there, so to speak. Monday 4/27, returned to work, took Provigil as usual, and by the end of the day...zappp, NO VOICE, my larnyx felt like there was someone choking me, laryngitis BIG TIME. Starting to get pretty scared, as there were moments where I felt gagged, I was having difficulty swallowing and at times, I thought breathing...needless to say, I could not sleep the entire night...not a wink...came to this site and saw It has been three days since being off PROVIGIL, pains in body subsiding, but rash is still there, laryngitis less (I can talk) still feel swelling to the larynx, like something is on it. The fingers feel like they are coming apart at the fingernails..strange, I can still type, but the tips of the index, and middle fingers are numb and tingly, PRAY FOR ME, THAT THIS THING GOES AWAY...IT LITERALLY CAME UPON ME...NO PROBLEMS FOR ABOUT A YEAR, I THOUGHT THE DRUG HAD CHANGED MY LIFE FOR THE GOOD...NOW I WONDER HOW MUCH OF MY INSIDES HAVE BEEN DAMAGED. IF YOU ARE NOT ON THIS DRUG DON'T START; IF YOU ARE GET OFF WHILE YOU CAN!! READ the new FDA Warnings which I had no clue of, read the leaflets that come along with the medicine, then hold on to your throat, YOU MAY BE NEXT... I am not out of the woods yet, everyday thought this withdrawal, something else happens...today I felt swelling of the face and eyes...DOES ANYONE KNOW ABOUT WITHDRAWAL?? I've read no prob to cold turkey...I'll let M 59 1 years
5/1/2008

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