PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  mental fatigue, depression Headache, loss of appetite, elevated BP, irritable & moody when I skip a day. I immediately experienced improved mental acuity and a brighter outlook. I used to be tired and dragging in the AM, but provigil helps get my day going early. I feel positive, more CONFIDENT and ready to face a long day. I used to remain quiet in meetings because I did not feel confident enough to express my opinion even when I had a good point in mind. I am no longer intimidated by meetings nor speaking up. The other positive effect is that I have a loss of appetite which allows me to eat less and stick to a reasonable diet without giving in to cravings. I noticed that I have to take the provigil on an empty stomach to experience best results. I also take CoQ10 for better cardiac health which improves energy levels. Provigil and CoQ10 are a good complement and are more effective when I've taken both. Not sure if that is true of others, but that is my observation. Note: I don't take provigil everyday, just on an as needed basis. That works out to be approximately 3 times F 42 4 months
5/8/2006
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 4  mental fatigue, depression Headache, loss of appetite, excessive talking, elevated BP, irritable & moody when I skip a day. I immediately experienced improved mental acuity and a brighter outlook. I used to be tired and dragging in the AM, but provigil helps get my day going early. I feel positive, more CONFIDENT and ready to face a long day. I used to remain quiet in meetings because I did not feel confident enough to express my opinion even when I had a good point in mind. I am no longer intimidated by meetings nor speaking up. The other positive effect is that I have a loss of appetite which allows me to eat less and stick to a reasonable diet without giving in to cravings. I noticed that I have to take the provigil on an empty stomach to experience best results. I also take CoQ10 for better cardiac health which improves energy levels. Provigil and CoQ10 are a good complement and are more effective when I've taken both. Not sure if that is true of others, but that is my observation. Note: I don't take provigil everyday, just on an as needed basis. That works out to be approximately 3 times F 42 4 months
5/8/2006
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 3  Trying to get a buzz, 2000mg Dry throat, sore forehead. I took 2000mg of Provigil trying to get a buzz. I bought it off the internet. It felt cool for about 5 minutes then my throat got really dry and congested. I had to go to the ER just to be safe. A week later I started having panic attacks. I had to go to the mental hospital. They said the Provigil unlocked all the stress I had from work/school. So now I'm on Celexa, Klonopin and Risperdal to prevent the panic attacks. M 26 1 days
4/30/2006
 4  Counteract tiredness of other drugs Minimal Hyperactivity, Insomnia if taken too late in the day This medication has helped me tremendously in functioning like a regular person every day. I take many drugs everyday for Treatment Resistant Bipolar Disorder and the main side effect of most of them is "tiredness". It gives me the energy I need to get out of bed and go out there and run my company and no one knows I am "sick" this way. I recently had a Vagus Nerve Stimulator (VNS) installed to try to put my BPD in remission. If it is successful, I won't have to take all of the drugs anymore, but for now, I am glad to have the Provigil to keep me awake while I still take them! F 32 8 months
4/18/2006
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 3  Sleepiness None to speak of, but tolerance is building up. 100mg was enough to help le stay awake from 7 a.m. to 8 p.m., now I fell sleepy much earlier (early afternoon). M 46 2 months
4/9/2006
 3  Narcolepsy first two days, I felt two feelings at once. speed and fatigue. Day 3 had to manage feelings of low thresh hold of agitation. same with day 4. Felt better as time went by. Easily dehydrated, needed to increase water consumption. diahrea, heart palpitations I am on 200mg in morning. It works slightly, just enough where before taking it, I'd not go out. This makes me reluctant to go out, but I do more now. The only major drawback is that when I am out, and it stops working around 11:00am to 1:00pm, I am caught where I am with major problems. I thought or hoped I would get more kick out of it. =-Drawback is that, My family says I look "out of it" more, and look more tired than before I took it. I feel genarally same, but a bit more alert I guess. F 37 3 weeks
3/24/2006
 4  Fatigue from unknown blood problem I clench my jaw like a madwoman! I've also noticed that I get headaches as well and there's the loss of appetite but that's a good thing since I could stand to lose a few...Problem I'm having now is that I seem to be developing a tolerance to it I'm good for a few hours before I start falling asleep at work. I love this stuff. I haven't been taking it for very long and I hope they can figure out what is wrong with my blood so I don't have to take it forever but for now it's worked great. I can handle the clenched jaw by keeping my tongue between my teeth and the headaches dim with ibuprofen. I do find that if I drink something with caffeine in it I do tend to get VERY drowsy and lightheaded so I guess it's back to sprite for me F 30 8 days
3/10/2006
 2  Adult ADD mild headache; tearful; irritable - everything seemed to either make me cry or really annoy me. Nice to not fall asleep at 7pm. Only took it for a few days before the crying and short temper seemed like they outweighed any advantages. F 53 3 days
3/3/2006
 4  depression related tiredness headaches I love this medicine, but my only concern is the tolerance I seem to be building. F 19 1 years
2/23/2006
 5  Chronic Fatigue, Fibromyalgia smelly urine, diareah I have been very productive at my job and more attentive to my family. I can now get through the day without 'juicing' on sugar and caffeine. My sexual desires have returned and I am actually getting out of my house when I am not working. F 34 1 years
2/18/2006
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 3  EDS, Mixed Sleep Apnea, PLMD, r/o N Prone to tears. Cried once for 4 hours - couldn't stop though nothing was wrong. Lifesaver for alertness, cognitive abilities restored. M 54 1.5 months
2/15/2006
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 5  Lupus, fibromyalgia etc The first few days felt very dark. Thats the only way to describe it. I felt a strangeness about myself, as if I was in a dark depression. My dr had told me that it was a side effect and it would pass. It did after about 4 or 5 days. For the past 4 years I have been in a constand slump. Unable to make it through the day without sleeping. I had to quit work, because I would be falling asleep at my desk. I tried everything. Nothing worked. Then I tried Provigil, and it works like a charm. I take 300mg per day and I don't know what I would do without it. I work again, 3 days a week, I actually put make up on again, something I hadnt done in 4 years. I spend time on my hair, I have energy to excersize when im not too sore from my other medical conditions. It makes me feel semi normal again, and for that im so so greatful. My insurance wont cover it because it's only covered for narcolepsy, so I get it from Canada, which works out a lot cheaper for me. I still have to pay, but no where near as much as self pay here in the states. And it's worth every penny. F 27 6 months
2/1/2006
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 4  EDS, Falling Asleep, Focus It's hard to know about side effects because of other meds that I know are causing side effects. I do notice the strong urine smell and I think that sometimes it causes me to stay up too late. However, it doesn't keep me awake. I am asleep within minutes of laying down. I take 300-400 mgs a day. It saved me having to quit my job. I can still take naps and go to sleep at night very easily. However, there are days when I still have sleep attacks. Although this has happened a couple of times in the afternoon, most of the time they are in the morning prior to 10:00 a.m. I take it at 7:00 a.m. It's like it takes that long to reach it's full effectiveness and alot of times I feel awake but still tired. If I don't take it for a day, I fall asleep all day long. I am discontinuing a couple of meds that contribute to my excessive sleepiness and I am anxious to see what happens after that. For the most part, I love this drug and consider it a lifesaver. Oh, and by the way, I tested negative for narcalepsy. F 47 8 months
1/27/2006
 2  sleepiness more sleepiness evidently it didn't work for me... it made me more tired! F 31 2 days
1/17/2006
 3  Lethargy from MDD Take 200 mg/day. If I have important event, will increase to 400/day. Severe ringing in ears. No physical cause found. Discovered Provigil as source by accident when I ran out of med. Ringing stopped then started again when med was resumed. Plan to DC if I can find good substitute. Generally think this is a good med. I have a history of poor sleep before taking Provigil. It helps with energy-just not enough for me. M 59 3 years
1/16/2006
 5  MS/depression-related sleepiness I've only been diagnosed in the last six months with MS, but I had been overcome with overwhelming exhaustion. After about two to three weeks taking Provigil, I started to finally feel like I had energy to do normal, every-day things. I haven't noticed any unpleasant side effects, except the strong urine odor, but I can deal with that. However, the best "side effect--if you can call it that--is that this has increased my libido unbelievably. I haven't felt like this since I was in my twenties. My husband wants me to thank my doctor for him for prescribing this medicine to me. However, he now thinks he'll have to get some Viagra from his doctor to keep up! lol I'm just worried that this "side effect" will wear off soon. F 45 6 weeks
1/13/2006
 4  sjogren's, fibromyalgia, At first I thought it was a miracle I was on 100mg because I could actually stay awake even go back to work, it even helped with depression, although one really bad side effect was that it made having an orgasm extremely difficult. I also was in the beginning of menapause and was still on the birth control pill which I still took religiously, and but got pregnant on Provigil, so I think women REALLY need to be warned about the fact that it does decrease the effects of some birth control. I miscarried the pregnancy. I have been on Provigil for at least 3 years I rarely require naps anymore and can stay awake a big miracle, I do not need as much Provigil as I used to. Sometimes now I feel like I have too many thoughts, or I can get more obsessive on Provigil. I have a feeling that it is connected to the Provigil but not entirely sure. I think Provigil is a great drug for people with fibromyalgia, sjogren's, and excessive day time sleepiness. I'm glad to see that doctors are treating some of these syndrome like I have with Provigil. For the most part it really has helped me. If it wasn't for the sexual side effects I would rate this drug higher. I have developed some IBS (the catch all phrase for the docs) a lot of stomach pain and wonder if anybody else has had problems in this way. I was hospitalized twice with extreme stomache pains. I wondered if anybody else has had "undiagnosed but problematic stomach problems since Provigil? It could just be an element of the sjogren's or fibro F 43 3 weeks
1/13/2006
 5  sleep apnea minor numbness of face/fingers; occasional headaches; minor nausea; urine odor (not too bad); diminished sexual appetite, but not a complete loss. ocassional tingling in torso area (chest) - not sure if its from medicine keeps me awake all day long; if tired, I will remain fatigued, but not necessarily sleepy; works especially well when I get 7-8 hours of sleep (using CPAP). can now read for hours (excellent benefit). M 38 2 weeks
12/30/2005
 1  Narcolepsy excessive dreaming,muscle twitches,still sleepy,occasional headaches,urine odor,no appetite,no sex drive,some nausea, dry nose,chest pains,hard time breathing i would not reccomend this medicine to anyone. my fiance has had nothing but problems since he's been on this drug. the only plus is he works third shift and it keeps him awake there and on the way home but as soon as he gets home he falls on the couch and goes to bed all day long. when he is up he treats everyone he comes in contact with like crap. we are going to try and find a natural remedy today. M 21 4 months
12/21/2005
 2  hypersomnia, EDS Headache, backache, tight throat, dry eyes and mouth, stuffy nose. Prescribed 200mgs, two times a day. First two days were great. I felt good for the first time in years. Not hyper, no energy "boost", just awake, alert and able to focus. However, I was so focused in my work that when I was distracted (phone, coworker, etc) that it would take me a few seconds to orientate myself. Somewhat surprised at how tired I looked, when I felt so awake. Noticed some back pain, slight headache and blurred vision, but thought it was due to the hours I spent at my desk working. I wasnt getting up as much as I normally do (moving around to stay awake). Coworkers asked if I was feeling ok as I was not as talkative as I normally am, again I attributed that to how focused I was on working. Didnt sleep well the first two nights (2 - 3 hrs at most) but woke up feeling good. By the afternoon of the third day, the first pill seemed to wear off and the second never kicked in. And it hasnt worked since. Headaches and backaches became worse, vision very blur F 51 11 days
12/15/2005

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