PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  day time sleepiness I take half a pill a day. A full pill and I can't sleep at all. It has changed my life. I can do things in the evenings that I could never do before. If you take it several days in a row it seems to have diminished effect. I dont know how I got along with out it. It also seems to keep me in a better mood. I am not jittery like adderal or Ritlin. But I also and not as focused. M 55 6 months
1/14/2007
 4  narcolepsy Well, I constantly slept. My parents would al ways get mad. I can actually stay awake all day. And accomplish things that I have been wanting to do. I still feel somewhat tired, but not tired enough to take a nap. I have not been taking Provigil that long but I already see a difference. F 14 2 days
1/9/2007
 5  narcolepsy some initial hyperactivity, light-headedness. Nothing severe. I was recently diagnosed with narcolepsy and started on provigil. The change has been incredible.. I can actually function as a normal person. F 24 3 months
12/27/2006
 4  Narcolepsy Nausea, light-headedness, scattered thoughts, inability to concentrate on one project for more than about 20 minutes without a "break"...but not picking it back up when I'm "rested" because I completely forget what I was doing. I get really moody, though and I have cought myself chewing my bottom lip off (literally layer by layer until it's bleeding), grinding my teeth, I'm WAY more talkative than I used to be. I guess it has it's good points and its bad because even though I'm stoked about being able to live through my day without wondering who I'm going to fall asleep in front of...I really could care less. Well, I don't fall asleep driving down the highway anymore. :) Or at the stoplights. OR in the doctor's office. OR at my desk at work. OR as soon as i walk through the door at home...especially if it's quiet. I would guess i could say it gave me part of my life back. But, even with that, if I slept through it I wouldn't know to care...but this is forcing me to "not" care because my body/brain won't allow me to care enough to process whatever it is I am allowed an opinion on. Then I have crazy stupid dreams...other than that, I suppose it's okay. F 29 2 months
12/27/2006
 3  SSRI Apathy and tiredness some chest pains, fluttery feeling, addictive feelings of "liking it too much", up and down portions of the day (i.e. when it wears off very tired, then back up on next dose). On lower doses I don't notice this as much but also don't get that great lift that comes with it. I read somewhere that the secret to this med is laying off for a couple of days (i.e. weekends). I think this is true. THere is a tolerance factor that develops that seems to make it less and less effective over time. I remember the first time I took it feeling quite happy and sort of buzzed in way that felt great. And took awhile to wear off. Now faster wear off and not as much of an energy burst. Potential for abuse and addiction is quite clear to me. Find myself looking to take it for important meetings and presentations where I need to be "on". So that feels a little like a developing dependancy and not as much of an adjuctive therapy.
12/26/2006
 5  Hypoxia due to brain injury side effects are strong urine odor and loss of appetite. i rarely feel hungry and have lost 35 lbs since I started taking it, insomnia Wonder drug gave me life back after hospital error which resulted in my getting 10x too much intrathecal med. developed hypoxia. i can finally drive and sit through church. no more embarassing moments of nodding of in inappropriate places. thank you God, F 53 2 years
12/22/2006
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 2  Narcalepsy / daytime sleepiness I have only been on it for one week. Im taking 200mg in the am and i feel nothing. I am sick by afternoon impossible to stay awake with constant headaches and nausea. One day I took 400mg in the am and felt like i had a huge rush for a couple hours. then i was left shaking and feeling sick. then a couple hours later i crashed. by 3 pm i was tired and misrable and in bed. I am not saying the headaches and nasea are from the medication because i feel sick every afternoon once i get so drained. Can anyone tell me if they have felt this way. i am desperate to feel better and enjoy life. anyone that feels like sharing please do. thanks. 26 7 days
12/14/2006
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 5  Fatigue from morphine painkillers Jumpiness, insomnia, ONLY when I take too much or take too late in the day. It's no different, really, than a strong cup of coffee - except that it's even LESS addictive. A wonderful drug for me, helping me overcome overwhelming fatigue that is a result of very serious painkillers I'm on that used to completely knock me out. I use Provigil only when I need to, and half - even a quarter - dose of 200mg helps get me through the day without any side effects. M 34 6 months
12/11/2006
 4  lupus didnt see affect for a few days, doesnt work as well as I had hoped. Most days it keeps me awake though. Side effects included, sudden severe mood swings (passed very quickly), excessive sweating, anxiousness, lack of concentration, overwhelming need for interpersonal contact/talking, teeth grinding, jitters. has similar side effects as a dose of adderal, just not as strong F 19 2.5 months
12/11/2006
 4  exhaustion, tired all the time I think I am experiencing nausea and stomach problems from this drug. It almost makes me need to eat even more though to stem off the nausea?? I didn't notice any difference at first, but I do think it has helped me be more alert/awake for at least the first half of the day. I have been taking 200 mgs or 100 mgs if Im concerned about the nausea. Has anyone else experienced these side effects? and if so have they subsided? I still may have lost weight even though I am constantly eating too! Please write for help/suggestions, I can't take the nausea! F 21 3 weeks
12/6/2006
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 4  apnea nausea and stomach pains The benefits have been tremendous! No more day sleeping, nodding off! I'm back into life again, EXCEPT...for the horrible stomach pains (like cutting class) and nausea-to the point I can't work- so I'm just as out of it with the side effects as I was with the sleepiness. Anyone else have this problem? Anything help? How long does it last?I'm a teacher so I have to be on my toes,and doubling over in pain, running to the Rest room, and burping and flatulence are not too cool. F 53 4 days
12/4/2006
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 1  ADHD / BiPolar Depressed / Fatigue If I feel any sort of hypomania or mania comin on, than I just take a provigil. Originally it was prescribed to combat the fatigue that came when I took Ritalin for ADHD. It has made the fatigue worse, and only makes me depressed. As I am typing this I am sitting here wondering why I am still taking this drug. F 31 1 years
12/4/2006
 5  Shift Work, daytime napping This is a weird side effect, and I didn't notice it until my sister came to visit, but she said I was driving her crazy with all the humming. And it's true that I hum all the time now, all kinds of songs from "elmo's world", to Mozart, to christmas carols. I used to hum from time to time but never like this. The upside of this is that apparently humming is good for sinuses. Has anyone else had this side effect? If so, please send me an e-mail about this. sleeping six hours during the day then 400mg at 9p when I went into work at 11p got me through my shifts as a night nurse and then 400 mg at 8a and 200 mg at noon helped me avoid naps on my days off, which was important because I have a two and a half year old now and have so much to do. When I was single I mostly stayed on a night schedule even on my days off. F 44 6 months
12/1/2006
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 5  ms/narcolepsy weight loss (15lb) in the first few weeks, jaw clenching, obsessive picking of scab................ Just did a sleep study without this wonderdrug - found I was unable to stay awake for even half an hour, This drug has given me my life back. F 40 5 months
11/30/2006
 5  narcolepsy Compulsion to push tongue against lower teeth, causing soreness. Slight loss of appetite. Somewhat depressed libido. I am taking 200 mg for mild narcoleptic seizures. I didn't actually fall asleep, but felt weird several times a day. These have been 95% eliminated, and I never feel drowsy during the workday. It seems to have an anti-depressant effect too. When I first started taking it, I had a compulsion to clean and organize the house, but that wore off. M 64 7 months
11/21/2006
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 5  Narcolepsy Mood Swings, No Desire to Eat, Irritable THANKS to everyone who has emailed me!!! I still have questions and want to know how everyone else feels about Provigil/Narcolepsy! EMAIL ME!! :) F 19 3 months
11/20/2006
 1  
11/18/2006
 1  Ehlers-Danlos (EDS), Insomnia, OSA Dizziness, hyperactive, talkativeness/talking very fast and mild euphoria during first two hours. Followed by progressive worsening of following side effects: chills, fever, dry mouth, headache, total loss of appetite, significant nausea, full body tremors (particularly bad in hands), tinglely feeling throughout body, worsened IBS, tachycardia (155bpm consistently throughout day), heart palpitations (pounding/fluttering heart) all day, some shortness of breath and a general unwell feeling. Worsened insomnia. I did not tolerate this medication well and had significant side effects, starting almost immediately, that lasted at least 20 hours after taking the medication. I was non-functional for the two days I was on it and several days after. Be extremely careful with this medication if you have any sort of heart problem, particular valve problems (even if not MVP), if you have or are suspected to have any type of ANS disorder like POTS, or if you've shown a sensitivity to other stimulants, even ones technically in a different class than Provigil. F 16 2 days
11/18/2006
 4  ADD Tiredness, dry mouth, Thirsty all the time (only in the first few days of taking it). Everything ok now. I am taking this for ADD and I noticed that the wired feeling I had all the time is gone after 20-30 min of taking it. Otherwise I feel calmer. My husband even said I can pay attention for more then 5 minutes! F 39 3 weeks
11/17/2006
 3  excessive tiredness and ms I take 2 200mg in am and 2 more in afternoon and im still very tired but not a bad as befor, If I forget I crash hard. Dark and smelly urin. A little OCD when I get in to things now they have to be perfect and my way or I cant let it go. I was never like that befor. Motor functions seem to be more jumpy since I started but that might be the ms more and just a quienq. All in all big diffrence but im thinking of trying somthing else. I take 800mg on an average day and I could still fall asleep if you show me a pillow. F 30 6 months
11/15/2006

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