PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  adult ADD - inattentive type Exhaustion, spaciness, tightness in joints, dehydration, headaches, nausea. I'll probably go back to dexedrine. I had high hopes for this med b/c i figured it was less harsh than amps... the first couple days I felt many of the above side effects, but felt really good about everything, liked everyone around me (similar to MDMA in that way). Another reason is I wanted to try it is that I thought this had lower abuse potential (I've been clean in recovery for 14 years). It seemed to help slightly with concentration at first, but the side effect are just too awful for me. M 39 7 days
5/11/2007
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 2  Chronic Low Grade Depression Headache for the first week. Loss of appetite. Soft bowels. Faster heart beat/chest fluttering at time and some loss of breath. Initially this drug seemed to work wonders for me. I started at 100mg a day and increased after a week to 200mg a day. I felt energized and my depression completely dissapeared. I was very motivated in a way I haven't been in a long time. However by the 4th week I began to crash in the afternoon. (I was taking the provigil in the AM) I would become overwhelmingly exhausted around 2-4pm regardless of how much sleep I had the night before. The fatigue was accompanied by a strong depression, much stronger then before I started taking the Provigil. I have had chronic low grade depression for years but it got much worse after 3 weeks of Provigil. I began to taper off about a week ago. I don't know what doctors are thinking when they say there are no withdrawl symptoms. I have been clumsy, forgetful, highly anxious (nervous tics) and very depressed since stopping the drug. I never have problems with clumsiness and forgetfulness so I know this is a result of withdrawl. But the thing that wo F 38 5 weeks
5/7/2007
 1  Excessive daytime sleepiness/ADD I got real tired about 30 min after taking 1st dose. The next morning I took it at 8 and went back to sleep at 11. Chills, fever, sore throat, felt like I smoked too many cigarettes. Dry mouth, Increased appetite, dark urine w/strange smell (like I was dehydrated). Clenching teeth and compulsive toungue/cheek chewing. Severe lack of concentration and forgetfulness This med made me feel worse than before I was on any stimulant. I had to drag myself around, felt crappy, like I was getting the flu. It was more like the opiate flu, the withdrawl symptoms of pain meds. I was hot. Took off sweater and I was cold. Felt like all the hairs on my body were standing up. All I wanted to do was sleep. Scattered thoughts, locked myself out of my apartment last night. Kept eating and eating, couldn't stop. These were mostly paradoxical effects, stoped after 1 day. Pharmacist didn't have any clue why I was reacting like this. F 28 1 days
5/5/2007
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 4  Shift Work Sleep DIsorder/Bipolar strange urge to smoke cigarettes. lot's of those half-way yawns. first few nights i had some crazy nightmares. i open a gym @ 5:30 am. after 2 months i was not able to adapt to that schedule. i would nap frequently for a few minutes at a time. always felt lethargic all day until id go back to sleep. as i would adjust weights in the gym id injure myself- even split my finger open and had to get stitches. i always got my full 7-8 hours so i was stumped. Provigil helped with these symptoms. i already take lamictal, celexa, and inderol. provigil affects birth control but i don't want to get off of it b/c my tits will shrink lol. F 27 4 months
4/29/2007
 5  Narcolepsy For approx. 10 days I experienced headaches but they have gone away. Taking Provigil has changed my life. For approx 7 years I was told I had depression, lupus, a form of migraines. Come to find out I had Narcolepsy which was causing my migraines. I was constantly falling asleep or just wanted to sleep. I had no energy or motivation. The older I got the worse it got. Since taking Provigil I have my life back!!!! I am a new person! Everyone around me has noticed the change. However on occasion I will have days of sleepiness and just wanting to sleep. F 33 2 months
4/28/2007
 5   Mild headache (infrequent), softer stools, excessive yawning I was diagnosed with Narcolepsy and began taking prescribed Provigil (100-200mg a day). The effects of the drug suppsedly last on average 8-10 hours. For me, it's more like 4-6 hours and split dosages work best (50-100 mg in a.m. and 100 mg in early afternoon). But it definitely does what it's supposed to. I will still get tired in afternoon but will no longer fall asleep. A lot of yawning though; and I usually feel the need to take deep breaths (an odd sensation in chest area) when succession of yawns occur (usually 8 to 10 separate yawns within a span of about ten to fifteen minutes). M 33 6 months
4/28/2007
 5  narcolepsy, EDS, OSA occasional dull headache, some minor increase in anxiety This is a wonder drug. I previously slept anywhere from 12-18 hours per day, and was still constantly sleepy. I was becoming dysfunctional and almost had several car accidents due to sleepiness. From Day One this stuff worked wonderfully - at first I became very euphoric, but that has worn off. I take it on an empty stomach, as taking it with food makes it not absorb as well for me. I typically take it in the morning and wait an hour or hour and a half before eating. This stuff has given me my life back. I can concentrate, think more clearly, drive safely, and cut back on my caffeine use! I am a pre-med student and thanks to Provigil I can get back on track. 200mg per day works just fine. Everything I've read indicates that higher doses are well tolerated, but do not produce additional benefit. It's expensive, and I had to get a pre-authorization - but all the trouble is WELL worth it. F 28 1 months
4/23/2007
 5  Fibromyalgia / Lupus Slight headache the first few days of starting the meds. A bit of a euphoric feeling, although not unreal. I think it was the added energy made feel good. I eat less, which is good for me. I have had fatigue for three years. This drug has saved my life. I have energy again, but not a nervous energy. I want to work, be with my family, begin and complete projects. This is really a revolutionary experience for me. I tried other meds and didn't like the Side Effects. I take 100 mg in the morning around 9 am. This lasts most of the day. I sleep well at night, sleep more soundly than I have in years and wake up ready to go. I also take an nsaid (non-steroid anti-inflammatory) for my muscle pain, but no other drugs. F 54 1 months
4/23/2007
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 2  Excessive daytime sleepiness Severe depression once eugoric side effects of Provigil (Modalert) wear off. I generally suffer from mild depression, but Provigil compounds this depression considerably and predictably turns this into a 'severe' form the evening or day after I take the medication. The manufacturer lists depression as a common side effect, so those who have a tendency toward depression should be aware of this before developing a psychological depedency on Provigil, which is quite easy to do. Aside from this, I did not have any physical side effects aside from, sometimes, a slight headache and decreased appetite. Perhaps muscle tension in my shoulders and back. Again, let me stress that the severe depression is clearly related to the Provigil withdrawal, and so I have stopped taking it altogether despite the temporary 'high' that I get for the few hours after I take it. Do not take alone as an anti-depressant, despite what you may have heard about its eugoric effects. For those who are mild to moderately depressed, Provigil withdraw may lead to suicidal ideation and severe depressive episodes that encourage a dependency with increased usage and dosage increases (tolerance develops rapidly), and so a dangerous cycle of psychological dependency can occur. It is great while it lasts, but so are many drugs. Use with caution. M 31 6 months
4/21/2007
 5  Excessive sleepiness None I take 100 mg in the morning around 8-9 am and it keeps me awake all day long until I'm ready for sleep around midnight or so. I had been falling asleep whenever I would sit down for longer than 20 minutes and being a chemistry student, this is not good on the GPA. I'm able to stay awake in class now and study for an extended period of time without wanting to sleep. I had gone on a week long vacation and had no withdrawal symptoms. I have not developed tolerance either. I like it because it keeps me awake without making me jittery like other stimulants and it's only a schedule 4 controlled substance. M 22 40 days
4/9/2007
 5  narcolepsy I have many "side effects but of what I'm not certain as I take a laundry list of medicines. Also, provigil does not remove the side effects of narcolepsy. It does allow me to be awake and with the help of an excellent sleep neurologist I'm gaining a faster wake-up, energy and drive. The provigil is the key to getting there. Incidentally, I use Alertec from Canada, manufactured under license, as it is considerably cheaper and is the same. I had to use it regularly for some time until I had the desired effect. I don't believe it's a "I need to stay up late tonight" drug. For me it's a miracle drug as I did not want to rely on amphetamines or ritalin. M 70 3.5 years
4/9/2007
 3  Narcolepsy The first two days it was wonderful! Then dizzy, cold chillz, real fast heart beat, pain in chest, and loss of all motor skills, Ima stop taking this stuff today before I get any more depressed! M 29 10 days
4/9/2007
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 3   Seem to have chest burning in the mid sternum area as well as chestpain in the nipple area. Anyone else relate to these side effects? M 4 months
4/1/2007
 5  Severe Sleep Deprivation/Apnea decreased appetite (good side effect for me) My wife calls this my happy pill, I take 200 mg at 6 am and 200 more at around 1 pm. It is wonderful! Has changed my life, I used to come home from work and just go to sleep in the chair, was constantly tired and no motivatin at all. Been on it a month and not one single nap since day 1. My wife calls me everyday at lunch to be sure I take my second dose, we actually talk again instead of her having to watch me sleep and nap in the chair. I actually look for things to do again. WONDERFUL!!! M 43 1 months
3/30/2007
 3  add not sure F 52 180 days
3/26/2007
 5  excess. daytime sleepiness I took this once before but I think I stopped because of its cost. I started it again today ,to replace adderall, which I have just discovered has been basically *giving* me ADD and OCD. As well as intense anxiety. Almost manic surges. Anyway--I will be able to describe provigil's effect in a few days. I'm writing now because many people have written here about jaw clenching, teeth grinding, and tongue biting as side effects. I have always had trouble with this, but after a horrific trauma, together with the adderall, I found myself biting my tongue at night to the point where I'd bitten at least halfway through on one side. I should go to a dentist and get a teeth guard to wear at night, I know. But meanwhile, I have completely stopped the tongue biting by working on the trigger points in and around my jaw. I accidentally came across "The Trigger Point Therapy Workbook" in a friend's house, and started perusing it. Later, when the jaw clenching became so bad, I bought th I wanted to respond to someone who wrote: "grinding and biting!! Any help?" See the section on side effects. F 39 1 days
3/23/2007
 4  narcolepsy Had insomnia the first night only. Have some ringing in the ears, but these are trivial annoyances compared to the great change this med has made in my life. I have only been on it a month, and I feel like I am truly awake after 20 years of sleep! I find at 200mg it wears off by 2pm, so I am going to ask my doctor to increase my dosage or let me take another 200mg at noon each day. This medicatiion has truly saved my life. F 49 1 months
3/21/2007
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 5  Escessive daytime sleepiness, depre None Provigil has really helped me a lot. Without any medication I tend to sleep 12-14 hours a day. Previously, I was on Adderal which worked well in keeping me awake and alert, but led to an increase in my blood pressure. Also I felt like I was always a little jumpy. The Provigil is great. I get the same benefit as with the adderal but it feels natural. No increase in blood pressure or jittery feelings. F 41 2 months
3/20/2007
 2  Severe Fatigue from Lupus and Depr. Within 1 hr of taking, felt more fatigued than I felt before. Almost fell asleep behind the wheel on my way to work. Trouble focusing and even speaking. Weird feeling. Felt very slow moving. Mild, constant headache. If I talked too fast or too much, I got winded and I felt funny. Sometimes I felt weird in my chest- can't really describe it. Slight diarrhea. Very clumsy. Sinus problems. Ok, all these symptoms are from day 1. I hope it gets better. Within 1 hour of taking this drug, I immediately wanted to go to sleep, and I was driving! The fatigue lasted all day and it was twice as bad as it normally was. I felt like I was on a downer all day. I am usually a fast mover and I moved like a snail all day long. I didn't even care though. If I tried to talk to someone, I would get winded and funny feeling (especially if I was talking fast). I am normally not clumsy and dropped everything all day long. Within 2 hrs of taking drug, I developed sinus issues. Hope this gets better, if not then this is def. not for me. Oh yeah, I also found myslef talking all day....to myself! Weird for me. I also couldn't focus when trying to do work and would forget what I was saying constantly. F 29 1 days
3/20/2007
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 5  multiple sclerosis Dry mouth only. Multiple sclerosis took my life away, and Provigil gave it back. I take 600 mg a day. I'm fine and I can still go to sleep at night. If I forget to take the medicine for more than a day, I feel like I'm in a coma. I've been on it for 2 years now. I don't no what I would have done if my doctor didn't prescribe it to me. What a life saver. F 36
3/18/2007

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