PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Extreme fatigue-only up 6 hrs daily @200mg to start stomach pain & nausea too much,but was super woman with speedy speech. Had to cut dose to 100mg & can tolerate. A little nap or rest around dinner,but this medicine has given me my life back. My stomach has been gurgling,but no pain. It causes me to smoke more due to being up & a little more hyper,but I will get a handle on,because I was in the process of quitting. My speech sometimes gets faster,but I think is leveling out some. Overall,this medicine has given me my life back. Hope a tolerance doesn't develop May try to increase back to 200 later only if my stomach will tolerate it,so that I won't poop out in the late afternoon. We'll see after another couple of weeks Hope this review helps you F 60 4 weeks
100 mg
1/22/2016
 2  Mental alertness & wakefulness Felt slightly more awake, Light niggling headache, Jaw clenching, Spacey at times, Foot tapping to average music, Foggy head, Staring off into space, Difficulty concentrating, Trouble focusing eyes. Day One: 200mg at 1700hrs before a 12 hr night shift, roughly 3 hours to feel noticeable effects. Felt slightly more awake, light niggling headache, jaw clenching (not cool for work), felt a bit spacey at times, foot tapping to average music. Was like all the undesirable affects of MDMA without the good if that makes sense. Day Two: 200mg at1600hrs before night shift, roughly 2 hours to feel effects though had less food in stomach. Initially felt more awake than previous night, very foggy head, light niggling headache, jaw clenching, foot tapping, staring off into space, difficulty concentrating, trouble focusing vision (again similar negative effects of MDMA) for those who have used. So far not overly impressed, don't get me wrong I wasn't expecting a limitless pill type effect but hoping for something like a Dextroamphetamine type experience with that kind of focus and mental drive. I have also read that taking too much can cause some of the foggy head side effects I experienced so I will try half dose next time and see how that goes. I also received some Armodafiinl in the sample pack so hoping that it works better for me....fingers crossed! M 33 2 days
200 1X day
10/13/2015
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 3  suspected narcolepsy, hypersomnia Restlessness, anxiety and sleep paralysis on the second day. No symptom happened again after that. Might stop working after a few weeks if taken daily. Ideal when taken intermittently; stopping (or taking less) before returning to the suggested dose usually fixes this. F 25 4 months
100mg 2X day
8/17/2015
 3  Mild Narcolepsy;TBI Hypersomnia; MS Increased wakefulness; increased concentration; improvement in cognitive function; improved memory; Severe headaches; anxiety (which can sometimes lead to feelings of parnoia); intermittent tachycardia episodes; tremors; occasional OCD episodes; increase in pain level--and/or reduced effectiveness from narcotic pain meds; increased muscle spasms, nausea My review is identical for Nuvigil and Provigil: The medication is very effective for drowsiness and improved cognitive functioning; standard treatment for narcolepsy. However I am unable to maintain a daily schedule due to side effects: terrible headaches, tremors, negativity, OCD, and anxiety--Sometimes feeling watched or that people are working against me--even when I KNOW this isn't true. The combination makes me very irritable and not very nice to be around With daily use and higher doses I've experienced OCD episodes and panic attacks--probably triggered by physical anxiety, which I've NEVER had before taking these meds. It's terribly disappointing as hypersomia is ruining my life--NO one can get anything done sleeping. Worse, when I take the nuvigil I either have to be selective as to when--so that my pain levels are relatively low--or up my narcotic due to increased pain and spasms. Nuvigil & Provigil do what they are supposed to do, but on balance the side effects are miserable, even after years. With dr's permission I take them PRN--but they aren't as effective; So I live like Rip Van Winkle, or suffer in pain and act like a nut, pushing everyone away. I can't take anything sedating which means going without certain treatments. Driving is out of the question. I'm lucky that the narcotics don't sedate me (when sleeping 36 hrs I'm not taking anything let alone pain meds). Or eat. Or drink..Or let my poor dog out...FYI: Adderall and amphetamine were not helpful F 59
1X day
8/1/2015
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 2  MS fatigue Took 3 weeks at 100mg before any noticeable effects. Upped dosage to 200mg at 4 weeks. Worked well for wakefulness, but had increased anxiety and extreme irritability. I'd rather be exhausted than awake and angry. M 35 4 months
200 mg
7/24/2015
 5  Study aid No trouble getting to sleep when I wanted to. I have never experienced such high levels of focus and concentration as when I have been taking modafinil. The confidence it gave me when revising made me feel like nothing could stop me getting the grade I wanted. I would be getting through a workload five times as big as I could without it and just reading, learning, understanding and applying everything so very easily. Incredible drug. No side effects. M 21 21 days
200/400mg 1X day
7/4/2015
 5  Narcolepsy Not much. Probably contributes to my clenching teeth. I have a rapid heartbeat, but I take Adderall too, so can't blame it on the Provigil alone. Provigil was a lifesaver. I initially started taking it due to sleepiness (they thought) from my Paxil. I had Tricare at the time so they covered it. After I divorced my military husband I got on a different insurance that required a pre-approval. That is when I had the sleep study and other testing and found I have narcolepsy. I actually take a combination of Provigil and Adderall. It is only 10mg of Adderall, but something about the 2 together works amazingly. F 44 10 years
200 1X day
7/3/2015
 5  Fatigue due to MS Inability to sleep if taken too late in the day. After needing to change MS medications, was faced with life altering fatigue. This medication had done wonders for my quality of life. Highly recommend. M 46 24 months
100mg 1X day
6/17/2015
 5  COPD helps my breathing Fast talking sometimes not each time I take one F 60 1 days
6/15/2015
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 5  Narcolepsy/Idiopathic Hypersomnia My first week of taking the drug I experienced headaches and loss of appetite. Those side effects faded and I have never had an issue with them again even going off and back on the drug. I talk a little fast which might be a side effect but could be normal. This drug is amazing for me. I am not jittery, I am not sleepy. I can stop taking it any time I want to and will skip doses when I am sick so I can sleep more. After careful discussion with my doctor I chose to continue taking it through my pregnancy and my son is perfectly healthy (I am not recommending this for everyone, just offering the data since there is almost no information out there. I would love to contribute my data to any research being done on this.). I used ritalin while breastfeeding and prefer provigil because I had no side effects with it. My biggest complaint is fighting my insurance every year. The prior-authorization required for a drug I have been on for 10 years is insane and they mis-process the authorization all the time which leaves me rationing my pills and stressing out and calling everyone trying to find out who messed up. I filed a grievance to see if I could get a waiver of the prior authorization requirement but they denied my request. F 33 11 years
400 1X day
4/10/2015
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 3  idiopathic hypersomnia Let me say to those out there that I had to fight w my insurance company all the way to a administrarive hearing level to get coverage. .. which I did In the beginning, and even still occasionally, I get the shakes along w a headache and rapid speech. A few time some mild anxiety. When I took provogil alone it did absolutely nothing. Still falling asleep at dinner table face first into my plate. Really. Dr. added adderall in late morning and a second dose around 2:30. Sometimes I glide right through the day with no problems; other days it seems I run from project to project and then back again, barely completing any of them, and then there are still other days that I feel as if the medication makes me more drowsy. For me it's a hit and miss. F 51 6 months
400 mg 2x
4/8/2015
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 1  Tired Terrible blood in urine, stomach pains, arthritis symptoms Horrible M 30 1 days
150
1/30/2015
 3  Lack of energy due to sleep pattern Non,BUT!!! I stopped taking it for about 5 months,over the winter,due to insurance non-coverage,and I lost 25 lbs,with absolutely NO effort.Went back on Provigil? I gained it all back in 3 months.Im rethinking Provigil now.Maybe it goes weird when its in your system for too long? Is 6 years too long? Its WONDERFUL at first.It starts very subtly,not like speed.It just seems like some ran a tab of estacy in a glass of water for like 3 seconds.But WONDERFUL! After 6 yers? I guess the thrill is gone.But ,Oh,what a six years it was!!! F 54 6 years
150 1X day
1/28/2015
 1  Extreme fatigue Rash, all over. Started about an hour after taking. I would rather be tired all the time than deal with this rash. Took a claritin to try and calm it down. Wish I would have read the risks before taking. Never again, no thanks. Looks like I'm going back to coffee and Red Bull. F 28 1 days
200mg 1X day
12/24/2014
 5  Bipolar Depression Slight headache (only twice), diminished appetite I have bipolar disorder and I used this while on Prozac. Prozac had got me out of the worst of a depressive episode, but I still felt flat and with a mood that was always just below normal. Modafinil made me feel slightly high, properly awake, and very motivated. In other words, it really worked for the depression, and there were no scary side effects - no mania, no anxiety, no risktaking behaviour, no agitation, no raised heartbeat or any 'speedy' effects. Also there was no sharp comedown - the effects just gradually wear off. The only negative effect a mild headache on two occasions and one paracetamol solved it. It makes you feel more mentally alert, but I did not notice any increase in physical energy. The effect started within half an hour of taking 100mg and reached a peak about 2 hours later. The effects last for at least 12 hours, so don't take it late in the day if you want to sleep. I took 200mg once and the effects were just a bit more intense and lasted at least 15 hours. After it wears off, appetite and sleep return to normal, and the next morning I felt normal. I don't take it every day, just when I feel I need it. I have not tried this when deeply depressed, only when I was coming out of a depression, so I can't say how it would work in that case. It certainly works in changing your mood from slightly low to slightly high. F 55 30 days
100 to 200 1X day
12/12/2014
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 4  Shift work disorder At first lethargy, headaches, feeling of living in a fog with little to no emotions. After the initial "trial" period I have enjoyed provigil. The only problem is if you take it daily with no breaks as with any other medicine the effectiveness diminishes dramatically and for some reason now the effects only help me for 4-6 hours after dosing but when I started I could take 100mg and be wired for 15+ hours. M 28 7 months
200mg
12/11/2014
Email
 3  sleep apnea, grad school This medication is very peculiar. I think diet affects it, because the side effects and overall efficiency change from day to day for me. I am definitely more alert, and when I "crash" at night, I fall asleep much more quickly. However, I feel more anxious and slightly depressed using this medication. Also, if I am very stressed (say, having a big paper due), the anxious side effects are hightened to the point I am physically shaking. On the whole, I am happy with the medication, I just dislike the frequency of the side effects. F 33 1 months
200mg
12/9/2014
 5  Sleep apnea, depression, tired all headache, stomach issues fantastic medication. I do NOT take daily. I take it in early am as needed. It keeps me awake and focused. It also gives me a sense of well being. M 60 10 months
100mg
12/7/2014
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 5  Ms fatigue Different every day - decreased appetite def runny nose, jittery a bit manic, muscle soreness , increased heart beat, constipation, high feeling half hour after taking After three weeks is working really well get tons done during day my house is spotless I've even cleaned the windows... I take 100mg have taken 200mg and def more manic I'll try 200 again soon initially lots of side effects but they are getting better F 46 3 weeks
100mg
11/8/2014
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 3  Sleep disorder / for concentration After two courses of 10 tables over 3 weeks: 1) improvement in concentration and focus (onset: 1-3 hrs after dose Duration: 6 - 8 hours) per 100mg tablet. 2) Could sleep right through nights without sleeping pills 3) strong metallic smelling urine 4) lost the euphoric feeling after exercise (endorphins affected?) 5) mood and thinking changes (more aggressive) unsatisfying thoughts 6) I am currently off the medication (about 7 days) and I think now my motivation is 25 - 30% worse then it was prior to taking the drug 7) loss of appetite whilst on the medication but my appetite has returned over the last few days. I am going to get another course and note the differences and reassess my intake. M 27 14 days
100mg 1X day
10/9/2014
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