PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  depression fatique, ADHD None Provigil is a MARACLE DRUG for me.It has changed my life completely! Before i started taking it, i couldn't even get off the couch. I had low self esteem and very depressed, lazy, and so severe social anxiety that I wouldn't even leave the house because of the fear and anxiety with interacting with people. Now I'm not tired or depressed anymore. I'm off the couch, going out of the house, doing things like hobbies, went out and got a job. I'm talking more like my old self. I've got the old me back. I feel great. Never better. I thought that i would always feel bad until I found provigil. I've been on every other ADHD medication and Antidepressants, and Tourette/OCD there are. And I finally it, the right combination of meds. I have ADHD, Tourettes, Social Anxiety, and OCD. The perfect combination of meds for me is Provigil, Risperdol, Cymbalta, and Xanax XR. Finally after 5 years of searching I've found the answer. It's wonderful. Progivil is the best thing thats ever happ M 19 3 weeks
9/10/2008
 2  To counteract the drowsiness None. It was like a placebo This drug may have well been a pill filled with flour. It did NOTHING for me. I still slept all the time and was constantly exhausted. It did not keep me awake whatsoever. Everyone praises this drug, but I don't get it, it didn't work for me. M 23 1 months
9/3/2008
 5  Alleviate sleepiness from Remeron I am taking 100 mg - 50mg in morning and 50 mg in afternoon. I had headaches the first few days and they went away when I took aspirin. I was proscribed Provigil to counteract Remeron, an antidepressant I am taking for anxiety. The Provigil not only made me less sleepy but also seemed to reduce my anxiety and depression. I have no side effects except very mild headache. I think this drug is great - expensive though, I hope it comes in generic soon. F 53 2 months
9/2/2008
 3  sleep apnea headaches, all over itching M 48 18 days
9/2/2008
 1  ADD, Lupus fatigue DANGEROUS!!! Temp. dropped to 95.6, then spiked to 103 in course of an hour. 24 hrs. of severe pain, then a week of weakness. I took Provigil for a week about a year ago, all fine, but I discontinued due to extreme cost. Still had a few samples left. Took three of them at different times and had severe reaction each time. Ended up in hospital once, very low oxygen saturation, dangerous drop in blood pressure. I thought it was flu and didn't connect it with the Provigil til the third time. Skin rash, aches & fatigue for week or more after each episode. I think it induces major lupus flares for me. BE CAREFUL with this drug. F 58 7 days
8/31/2008
 5  Nightmares Speedy heart rate, headaches, irritability, increase in OCD symptoms, panic attacks, delusions, shortness of breath. Severe long and short term memory loss. My doc prescribed Provigil to me when I stayed at a sleep clinic for a few days to determine the cause of night terrors. I hate pills and rarely took the sleep aids I was prescribed to I tried it out. It is supposed to "keep me up all day so that at night I crash and have deep sleep to prevent night terrors." Horrible headache at first and I was totally "speeding". My OCD symptoms came back...disappointing. Now I have panic attacks and an underlying feeling of dread. I still take it, otherwise I would be asleep at my desk every day. I do feel it is a greatly beneficial drug but you def must determine if the side effects are worth it. F 30 3 years
8/27/2008
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 3  MS RELATED FATIGUE Difficulty breathing (severe at times), loss of voice/hoarse voice M 180 days
8/16/2008
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 1  Narcolepsy Good side effects: More talkative (especially good for me given my problems with extreme shyness), Think more clearly (if experiencing exhaustion-induced brainfog), Increased creativity, Mild euphoria, ---Neutral side effects: Strange smell of urine, Altered sense of taste, Greatly increased thirst, Increased urination, Nausea, Increased heart rate, --Bad side effects: Sore, red eyes, Headache on sides of head, Strong "gut feeling" that I didn't want to take the 2nd dose (back when I first started taking it, I was following the label for dosing twice daily), Delayed sleep if I took the second dose, Occasional distorted thoughts, Increased sound sensitivity, Chest pain, Inability to concentrate on specific tasks, --Really bad side effects: Numbness in center of forehead, Feeling very sick and exhausted for a whole week after stopping previously, Strange, unnatural feelings, Feeling horrible if I allowed myself to nap while on Provigil Crashing a Let me just say that when I started taking it, the first week was Great. But after that, I took it on-and-off, and the effects were increasingly inconsistent. Sometimes it worked, and worked very well, other times I would be in a stupor for the entire day, even with the medicine. Days when my thoughts were completely distorted became more common, and there were weekends when I would be essentially crashed the entire time but I attributed it to the sleep disruptions at night. The side effects got worse through this time. Last night, I had another horrible crash. I started feeling horribly exhausted at around 10:00, and went to bed. I slept for one hour or less before waking up, feeling the most extreme version of a nightly crash that I had ever felt... except that I wasn't sleepy. The headache, the numbmess, the weirdness, hyper-sensitivity to the environment noise, all of the negative side effects were there... and I was wide awake. Not just awake, but WIRED. I had a completely te M 27 2 months
8/16/2008
 4  ADD/daytime sleepiness/depression On a dose of 200mg (once in the morning), jittery movement and rushed talking, extreme impatience with people, extremely decreased appetite, insomnia. However on a dose of 50mg in the morning and 50 mg in the afternoon, barely any negative side affects. When I was first prescribed Provigil, I was almost obsessed with it, and its "magic" to make me the person I wanted to be. More productive, and much more energy. But with 200 mg (or more) in the morning, I was constantly agitated, I started to pick fights with people (when I'm not normally like that), and I barely ate any food at all (which I liked, but wasn't healthy). At the time I was also taking Prozac and Wellbutrin XL, but started them a year before the Provigil. In March of last year, I had a drug induced psychosis after taking too much cough medicine. I know the main reason was the cough medicine, but I'm still convinced the excessive amounts of Provigil didn't help. For weeks before my psychosis, I wasn't sleeping or eating...and the addition of more drugs that didn't let me sleep or eat just pushed me over the edge. Today though, I take only 50 mg in the morning and 50 mg in the afternoon. I use it to get basic things done, and it does help me a lot in school wit F 19 2 years
8/14/2008
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 5  
8/7/2008
 5  Narcolepsey Felt slightly dizzy the first few days, otherwise I don't experience any noteworthy side effects. I started taking Provigil about 8 years ago after being diagnosed with Narcolepsey. I originally started out with 200-400 mg per day and now take 400 mg in the AM and 200 mg in the afternoon. This pill has been a sort of "miracle drug" for me - it allows me to function and not be a zombie, and I don't experience any highs or lows from taking it. There are still times that I feel the need to take a nap and can't stay up as late as most people, but I honestly don't know what I would do without it. F 24 8 years
8/7/2008
 4  sleep apnea, chronic fatigue headache, itching, anxiety, jaw clenching, smelly and dark urine, palpatations It really helped me stay awake and alert, it helped with mood and depression, I could stay awake all day without having to take a nap. It helped me to think clearly. F 29 4 weeks
8/7/2008
 5  sleeping too much europia M 56 3 weeks
8/6/2008
 5  shift work sleep disorder Excitablility. A miracle drug. I was prescribed this medication because of excessive sleepiness during my 10 pm to 6 am work shift and sleeplessness upon going to bed. Not only has is helped me regulate my sleep/wake cycle it has also helped cure my major depression. I suffered for most of my life from crippling depression. I have been mostly unresponsive to traditional drug treatments and conjunctive psychological therapies. I can’t say exactly how this drug did it but it did. I FEEL NORMAL (whatever that is) for the first time in my adult life. By feeling normal I have been able to change destructive thought patterns through counseling and SSRI drug treatment. M 30 2 years
7/28/2008
 1  unexplained sleepiness Near-death. I have already commented about how this drug nearly killed me. I have studied it more since. If you are like I was, when you read that a drug has killed or badly injured someone, you will say, "Well, for every drug there are a few people who cannot tolerate it. That's life." But Provigil is not one of THOSE drugs. Consider this: In its own testing, Cephalon, the company which makes Provigil, found that 2%, 1 out of every 50 people people who took Provigil developed low blood pressure, also called hypotension. Then look through this list of over 300 people. Count how many of these 350+ people reporting here say they developed hypotension after starting on Provigil. I count exactly one person. Yet if Cephalon's own statistics are true, then there should be closer to 7 people (1 out of 50) reporting low blood pressure. So why aren't there another 5 or 6 people on this list reporting low blood pressure? Well, the one person who DID report hypotension was me. And it was hypotensio M 5 weeks
7/28/2008
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 5  fibromyalgia slight trembling in fingers, butterflies in stomach This drug saved my life! Has not only improved "brain fog", but has alleviated my pain, which I've not heard other FM patients describe. I don't take any other meds for my FM, and can feel pain returning if am late with dosage. Take 200mg per day. Feel less pain, less fatigue and the brain fog has lifted! Is like being reunited with my old self! I encourage anyone to ask their Dr. about provigil. Am sure is not right for everyone, but for me, has been the BEST! Do not have insurance, my nice doctor gave me free samples...but will find a way to pay whatever I have to. The benefits are just too great! --- insurance pays for viagra, but not provigil?? We all need to start complaining and get our voices heard! F 42 10 days
7/26/2008
 5  Sleep Apnea occasional headaches, strong-smelling urine, slight anxiety, disrupts sleep schedule if taken too late, suppressed appetite (lost 20 pounds in the first 2 months of being on Provigil--but I needed to lose the weight), loose/soft stool This truly is an amazing drug. I'm taking 400mg every day; 200mg in the morning and 200mg in the afternoon. I'm currently using CPAP for "obstructive" sleep apnea, though my ENT doctor was unable to identify any obstruction, but I'm in the process of investigating thyroid issues potentially caused by a pituitary tumor--which may actually be causing my sleep apnea. In any event, CPAP isn't working too well for me, and I suffer from excessive daytime sleepiness, compounded by my recent thyroid problems, which make me feel more tired, as if this were even possible. Provigil's side effects were very noticeable for me at first, then became much milder after the first week or two. I'm able to stay awake and alert more easily during the day whereas I used to fall asleep in every single class during college (recent grad) and perform extremely poorly in classes early/late in the day. I wish I had started Provigil much earlier, because I've been exhausted my entire life, to the point w F 22 11 months
7/23/2008
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 4  Obstructive sleep apnea mouth ulcers, very sore tongue, metallic taste, change in smells, some difficulty swallowing Had more energy in the day time. It definitely helped. However, due to side effects, am not taking it now. Was taking 200 mg per day for about 6 weeks. Will try smaller doses and/or not taking it every day after side effects wear off. F 65 45 days
7/23/2008
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 3  Narcolepsy (mild) jaw clenching and teeth grinding, itchy skin w/ light rash, mild anxiety, headaches Seems to work ok, not great. Headaches annoying and not as bad after time but itchy skin worse after time. Not sure if the jaw clenching/tooth grinding is due to Provigil - have had this from stress in the past but it is much worse this time. Would be ok without the side effects. F 36 50 days
7/14/2008
 5  multiple schlerosis weight loss I started taking 100 mg of Provigil a year and a half ago. I am now up to 200 mg one time a day and I take it around 11am. My concern is my weight. I was 183 pounds, I am now 132 pounds. I have also mad dietary changes that includes a lot less carbs. Potatoes and breads to name a few. Not that they are 100% out of my diet, maybe 75% from my diet. People are starting to look at me as if I am not doing the right thing. I love that I have so much more energy to feel normal. F 39 18 months
7/5/2008
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