MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Restless Legs None I have had undiagnosed restless leg syndrome for years. The problem caused me to quit taking car trips, going to the movies and quit taking classes because I could not sit still for more than about 20-30 minutes. Some nights I would have to get out of bed and walk around the house for 30 minutes just to get relief. Back in November 2004, I had a sleep study done and I was diagnosed with SEVERE RLS and mild Sleep Apnea. I was put on a CPAP machine for the sleep apnea and prescribed .025 Mirapex for the RLS. Mirapex has really helped me, I no longer experience any of the symptoms that I once had. F 50 8 months
7/23/2005
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 3  RLS At first, none. After 5 years, major augmentation, daytime sleepiness, lack of ability to concentrate, swollen ankles/lower legs, pain in thighs, cramps in feet and calves, weight gain, fatigue, occasional episodes in arms. I started with 1 25mg pill before bed, and it worked great for about 3 years. Over the past 2 years, I gradually increased the Mirapex to 4 per day. I added Neurontin about a year ago, and am now up to 3 per day. Despite the amount of medication (or maybe because of it??) I am having symptoms throughout the day, and it's really tortuous at night. I'm only sleeping a few hours at a time on a good night, and on others I'm up every couple of hours to walk and stretch. F 41 5 years
7/20/2005
 5  rls sleepiness, increasing nausea lately, dizziness and confusion. symptoms vary but loss of appetite has made me lose 15 lbs recently. all that food and no interest in it! the miracle is that my rls symptoms vanish when I take 0.25mg about 2 hours before sleep. only good marijuana has had that effect before. M 67 2 years
7/19/2005
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 4  RLS none originally prescribed .50 mg at bedtime. I found that .75 mg works better than .50. Occasional relapse with RLS happens but is nowhere near the severity it was pre-Mirapex M 37 4 years
7/14/2005
 2  RLS; Insomnia Unexplained muscle twitching in my legs when sitting for any length of time (i.e., movie theatre). Increased dosage from 0.75 to 1 mg daily at bedtime. Still wake up very tired. Have dozed off while sitting in car at stop light. M 51 1 years
7/13/2005
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 5  RLS Steady weight gain with no explanation, severe edema, hands & feet spasms, muscle pain, extreme fatigue & low endurance & alarming reduction in lung capacity (never smoked). I initially loved Mirapex because RLS is torture & it really helped! Now all these problems! 2 years ago: inital dose of 25mg as needed (2 x week); then 25mg every night; then 25mg very specifically between 6pm & 7pm; & now twice a night, at 6pm & 10pm. The more I take the worse the problems! F 56 2.5 years
7/12/2005
 5  RLS No side effects. It seems to have cured my RLS. I now sleep at night! It is wonderful. M 51 21 days
6/30/2005
 4  EARLY PARKINSON'S SLEEPINESS IN EVENING M 63 5 months
6/14/2005
 3  Fibromyalgia, back & outer leg pain So far only very emotional and memorable dreams. I wake up in the morning feeling they were real which causes me to be upset. I've only taken .25mg for the first 5 nights and am working my way up to 2mg over an 8 week period. Not sure of the effects yet. I did want to make reference in regards to the people who had nausea & vomiting. My Dr. has prescribed me Nexium (heart burn medicine) to take 3 pills 1 hr before taking the Mirapex. Then slowly work down to 1 or none. This is to prevent the nausea & vomiting. Since I have taken the Nexium I haven't experienced this. Something to ask your Dr. about if wanting to still try the Mirapex again. F 31 5 days
6/4/2005
 4  RLS, tarsal tunnel syndrome I feel a little bit far away from my self. THe pain is better though. The first time I took it, I went to sleep and only jerked once. I actually slept GOOD and woke up feeling better without the pain in my legs that is almost constant normally without it. I also take neurontin and it helps some too. No nausea/vomiting at all. F 37 14 days
6/3/2005
 3  Restless leg syndrome I am not sure if any side effects. I do feel that my thought patterns have changed. I think I have more trouble focusing. It does seem to have helped with the rls and sleeping somewhat better. I have developed some sort of pain in wrist and arm - may be unrelated but noticed some have complained of joint pain. I definitely have increased joint pain. Doctor is increasing my dose incrementally to help with my poor sleep. I have been diagnosed with rls and moderate acid reflux. I am on medications for both as well as asthma and allergies. Wonder how all these drugs interact. F 44 8 months
5/25/2005
 3  PLMD Nausea, difficulty falling asleep I'm also being treated for pseudomembranous colitis which could be contributing to my nausea, I'm ramping down on Klonopin to Mirapex and so far so good except for the vomiting. F 34 7 days
5/23/2005
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 3  Parkinsons Minor hallucinations, insomnia, blurry vision for a period after waking, swollen ankles, weight gain (spare tire). On the positive side the drug seems to act as a mood elevator for me. People have commented that my disposition has improved. Mirapex has been somewhat helpful in reducing tremors, whereas Artane and Amantadine did nothing. I am not taking any other medication yet. I am now up to 1 mg 3 x day, but I am experimenting with lower dosage again to see if side effects can be reduced. M 65 8 months
5/20/2005
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 5  Fibromyalgia..RLS initially: nausea;extreme fatigue. Now: some insomnia, possibly some irritability & bit of obsessive behavior. F 58 8 months
5/4/2005
 5  Restless Legs Mirapex has been like a miracle for me as I have suffered from RLS for years butI have developed leg pain(outside of legs from hip to knee)which even pain killers don't relieve. This happens after several hours in bed.Am wondering if anyone else has had this effect. F 80 2 years
4/28/2005
 5  restless legs Nausea, loss of appetite Have been taking for 3 months at 1.25 prior to going to sleep. When I increased the dosage to 1.25, the nausea and loss of appetite started. F 53 3 months
4/20/2005
 2  RLS I've taken mirapex for about 4 weeks - I've had very memorable or emotion-laden dreams, my left leg and foot have had muscle spasms/cramps; I've been unable to get to sleep, I've felt increasingly anxious and depressed since I'm already taking other meds for depression, I can't sort out what is mirapex vs. non-mirapex; I don't know how bad the RLS is/was, but (IMHO) I feel worse than 'before' F 55 4 weeks
4/16/2005
 5  Fibromyalgia Slight daytime somnolence and loss of appetite. I have been dealing with fibromyalgia and associated conditions (TMJ, IBS, migraine, carpal tunnel, etc.) for 8+ years. This is the first medication to help and nearly eradicate all of my symptoms. I am currently taking 1 mg and working up to 2 mg. So far the results are amazing! F 38 4 weeks
4/14/2005
 4  Severe periodic limb movement disor severe nausea if I tak it on an empty stomach, or am sick with something else. tiredeness, but since I take it at night, this is actually beneficial as it only takes me 20 or so minutes to fall asleep instead of hours. sleep greatly improved, actually only need 8 hours now instead of the 12+ I had needed, and I wake up feeling refreshed and rested. in reference to an earlier comment, I was on effexor before starting mirapex, and was told that the effexor may be part of the reason I have periodic limb movement. Also before mirapex we tried requip, which made me very anxious and hyper, an uncommon side effect, so it's always important to keep an open mind, what effects one person one way, doesn't neccesarily effect someone else the samer way. F 21 8 months
3/29/2005
 3  RLS/PLMD/Sleep Apnea I am not aware of any side effects of this drug on me, except maybe making me a little sleepy but that is the point of taking them in the frist place :-) At first I was taking one .125mg a day, then I started taking 2 a day. After the first year and right now it is virtually impossible for me to sleep without Mirapex. I am now taking 1 or 2 by noon and 3 or 4 around 5 pm. It allows me to fall asleep, except when I do wake up, if even 2 hours later I will not be able to get back to sleep. M 49 2 years
3/10/2005

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