MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  restless legs Severe pain thought my entire body, every bone in my body hurts, stomach pain, hart palpitation, difficulty in walking, back pain, can't work or sit for any length of time. The restless legs symptoms are gone but the side affects are terrible. F 67 2 months
o.125 1X day
3/17/2016
 2  RLS and fibromyalgia Constant eye twitching, locked jaw, sore joints, binge eating, chain smoking, excessive spending It did help my RLS a bit. I had no nausea etc. Biggest help was change of diet and homeopathic remedies. Totally changed my life. I had systemic candiasis which is now gone and so are my RLS and fibromyalgia F 36 3 months
2/24/2016
 1   Mirapex made me extremely nauseous. Took it before bed and woke up power-puking, and was sick to my stomach all day - could barely get out of bed. This was not a 24-hr. flu. I did not feel at all sick. It was from the medicine. F 54
1X day
2/21/2016
 5  rls I have been taking this drug for many years and it has saved my life my legs are so bad I go crazy but with this drug I am hole sorry for the haters I have no side affects M 55 10 years
3mg
2/20/2016
Email
 1  RLS Compulsion, heightened sexuality, affected normal judgment. I have been away from Mirapex now for 5 years and want to offer perspectives from a distance. As you can read from the many comments below, this drug affects people very differently. It was very bad medication for me, even at low dose. It didn't perceptively help my restless legs. What I didn't like is that the drug taker doesn't realize the side effects. For me the side effects were impairment of judgment, non-gambling compulsiveness, and heightened sexuality. As to judgment, something about which I am normally praised, I describe the effect as juvenile - not caring about the results of actions. As to compulsiveness, my focus was a house remodel project, for which I was totally absorbed and spent way too much. As to sexuality, I just had a heightened sense of sex and got way too close to a fellow worker. That almost ruined my 35 year marriage, but my wife, a psychotherapist, knew something wasn't right and checked on Mirapex. It takes a long time to get Mirapex fully out of your body, for me at least 6 months. Mirapex could have been a disaster for me if I kept taking it and if I increased the dosage. My wife also found a potential connection between Mirapex and a family history of manic-depression, which my father had. My advice: if you take this medication, be very aware of your individual results and be very open with your caretaker about what is happening; the side effects can be very subtle. M 68 1.5 years
.5 MG 1X day
1/2/2016
 4  Head injury that gave me rls I stopped mirapex for requip but had bad withdraws from mirapex body locking up like my jaw and every joint on my body hurt I have now returned to taking mirapex M 55 10 years
3 mg
10/9/2015
 5  for rls Requip gave me severe nausea. I have had no side effects from Mirapex. F 60 1 months
o.50 mg
8/30/2015
 1  Rls I took the pill few hours before bed time. I immediately started vomiting it continued all night until eleven the next morning. I had terrible headache for two days felt extremely weak still had nausea after two days. I also had flu like symptoms and felt drugged. I don't know if the dose was to strong but I will be looking for something else. Would not recommend the drug.. F 66 1 days
1
8/13/2015
 2  Restless Legs Fatigue, loss of appetite, hiccups, mild nausea, mild upset stomach. So technically my restless legs stopped but all the side effects make me feel terrible! This is not worth it for me. I will be exploring other options. F 37 4 days
0.25
8/12/2015
 4  Parkinson's Dull headaches when I started the medication. Dull headaches subsided after 2-weeks. The tremor in my left hand is not as prevalent. The Mirapex has definitely improved the tremor significantly. I have the beginning stages of Parkinson's and I work full-time. The medication has not affected my memory or sleep. M 57 1 months
0.25 3X day
6/11/2015
 1  Fibromyalgia Immediate massive headache, muscle twitches, inability to sleep, and didn't feel like myself. I knew immediately that this drug was messing with my head and would do the same damage to my life that Ambien did. Not worth the side effects at all. F 46 1 days
.5mg
6/2/2015
 1  Restless Legs compulsive gambling, feel asleep while driving, helped with RLS but ruined my life! Mirapex caused me to become a compulsive gambler. It has put such a financial strain on my family. I also have become very depressed because of the person it turned me into. I've had a hard time forgiving myself for the things I have done and the pain I have caused my family. I had no idea Mirapex was the reason I had become this way. STAY AWAY!! F 39 1.5 years
1 1X day
5/21/2015
Email
 1  restless leg Lost money, jobs,divorce, alcohol abuse,and spending sprees F 45 7 years
25
3/25/2015
Email
 1  RLS Horrible nausea, vomiting M 49 1 days
.125
3/12/2015
 1  restless leg My father committed suicide. At the end of his very short letter he said "my mirapex has messed me up". M 64 1 days
3/11/2015
 5  rls Weight gain, memory loss, confusion, insomnia, anxiety, twisting and tightening of my muscles compulsively. In the first few yrs of taking mirapex, i was taking low dose and only when i needed it. Of course the rls beast continued to grow and i now cant go a day without mirapex. But now that i take it constantly and at much higher dosage, i am experiencing crazy side effects. Rls is a living hell, it really is. I have experimented with a few other meds like requip and they did nothing. Im terrified because the beadt is out doing the mirapex and my body is not handling the increase well. But the thought of having nothing to ease the hell is something i cannot even fathom. What am i supposed to do? F 50 5 years
1mg daily
1/24/2015
Email
 3  RLS No real side effects for 9 or so yrs, worked well but I steadily had to have dose increased from . 25 mg daily to present 2 mg daily as RLS rolled over the meds. Now I'm sure Mirapex has augmented since RLS NOW affects one or two legs at a time, going into thighs, happens anytime day or nite, can last 20 min. or all nite (lately all nite), have more and more leg jerks and my tricks (like hot water on my legs from shower or laying down for awhile) do not work. I've, of course, developed a horrible sleep pattern of absolutely no sleep or if I'm lucky 3-4 hours per day. Becoming scared to drive, afraid of nodding off like I have when talking with people. I'm being switched to Requip but am not expecting much. My sister takes Requip for mild RLS symptoms, nothing like mine. To finish up, I hate RLS with a passion ... It steadily gets worse and control is near to impossible the longer it goes on. Unless yr doctor has had personal experience with this condition, I don't think they ge F 72 11 years
1 mg 2X day
1/19/2015
 1  Restless leg syndrome Severe gambling addiction and shopping addiction I would not recommend this drug to anyone. It has ruined my life. I have lost everyone close to me. Since discontinuing this medication, I am no longer addicted to gambling I have suffered severely from taking this drug. Any comments from anybody else who also affected with an addiction from taking this drug or Its generic, Pramipexole, please don't hesitate to contact me. F 65 10 years
3 MG
1/4/2015
Email
 5  RLS Originally it made me somewhat nauseous and dopey. I stopped it, went back on Requip, quit that, and tried Mirapex again. Never had a problem after that. I was originally prescribed Requip for RLS, but found that it stopped working after a relatively brief period of time. Switched over to Mirapex and never looked back. Works like a charm. An added benefit is that is makes me drowsy. I take before bed so that's perfect. F 58 5 years
.50 1X day
12/21/2014
 3  Periodic Limb Movement Disorder Hallucinations when I took too much, none at my regular dose I got put on this for PLMD and for the first two months it worked great, but then it slowly lost efficacy to the point I had to double or even triple up on my dose to get relief. One night, I took five of them and had mild hallucinations. My doctor switched me to Flexeril after I told him it was no longer working and he told me this was common for this med. He said nearly all patients experienced a burnout on it and it completely stopped working for them and they had to switch to something else. M 29 5 months
0.25 1X day
12/17/2014
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