MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)Average Rating: 2.8 (431 Ratings)Filter ResultsCompare MIRAPEX with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 |
More on MIRAPEX: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR MIRAPEX | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 5 | RLS | Have had RLS for 45 years. Mirapex is great, but am concerned about weight gain and bloating. | I feel I sleep well but am exhausted during the day. I almost fall asleep while driving and have a hard time staying awake. Have gained alot of weight and feel bloated. Alot of gas and diahhrea. | F | 56 | 4 years | 9/28/2006 | 5 | RLS | None | Amazing! I've had RLS since I was a teenager and normally suffer with restless legs nightly, but since I've been taking Mirapex, I haven't had one episode! | F | 44 | 14 days | 9/20/2006 | 1 | Nervous leg | Dependency on the medication. I had alot of problems falling asleep. After 2 sleep studies I was told I had nervous leg. Never seemed to be a problem for me up til then but they are the doctors. So I started taking Mirapex. I now have nervous leg and the sensation of my legs falling asleep starting around 9:00pm every night. I take 1.5 tablets. It takes about 2+ hours for it to start working. Then everything is ok. If I do not take the medicine my legs are so bad that I have to stay awake all night. I do alot of walking. Even trying too back off the dose does not help. | My life is 10x worse since starting this medication. I don't belive that I had a problem to start with (nervous leg) and now I have a drug dependency. My doctor has no explanation. | M | 53 | 3 years | 9/17/2006 | 5 | Restless Legs | Severe nausea in the morning after taking the drug, combined with anxiety. I decreased the amount to .125, which works fine. The drug is well named--it has been a miracle for me. I sleep all night and wake up alive, for the first time. So far, I've even quit grinding my teeth. | I've had RLS all my life, before I could describe it and well before it had a name. For most of my life, doctors just looked at me funny when I tried to tell them how agonizing it was; finally I quit trying to tell them. If this drug ever goes off the market, I will be one of those pathetic characters trying to score it on the street. | F | 65 | 6 months | 9/12/2006 | 2 | Periodic Limb Movement Disorder | Helped me fall asleep quickly, but I would have disturbing dreams in which I felt paralyzed and as if I couldn't breathe and would die if I didn't awaken quickly. These dreams would happen once or twice nightly, and they were very lucid. Dr. has given me sample of Requip, which I am nervous about trying, as I don't want the dreams again. | M | 34 | 30 days | 9/11/2006 | 3 | PLMD | Mirapex most often allowx me to sleep, but before I discovered that taking more than my usual dose of 1 mg at bedtime makes me vomit the next day, I took 1/2 mg extra and each of the couple of times I did that, I ended up with vomiting for hours the next day. Every once in a while it doesn't work at all, and my legs jerk me awake over and over, of course preceded by the tortuous restless, wormy feeling, which is often in my arms also. I then decide to just get up and stay awake since I prefer that to falling asleep over and over only to be awakened in a few seconds by the leg jerking and the very uncomfortable feeing in my body that is difficult to describe. It is like falling and then abruptly being jerked. I guess that is the sleep onset, which is then abruptly jolted by some opposite, and intense brain process. That is the only way to describe it. I also wake up in the middle of the night and have to hope I can return to sleep. The awakening is not due to PLMD, I just awaken. I | I wonder if because I have taken it for year, if Mirapex is now required by my body, and I would not sleep for days if I tried to go off it. The day time sleepiness is a huge problem and I wonder sometimes if I will fall asleep at the wheel while driving. I come close to that. I do think it has antidepressant effects, but I also have over the past few years to develop what seems like a shopping disorder. That is new to me. Just today I read that mirapex is a suspect in compulsive gambling and other compulsions. I wonder if this is contributing to my need to buy new things. I also read about circulation problems in the legs and ankles either a concommitant condition or a side effect of RLD and PLMD. I worry that I may develop such a bad case of PLMD, that I won;t be able to stay asleep at all. | F | 62 | 3 years | 8/20/2006 | 1 | FMS related pain, RLS | Violent vomiting that lasted over 24 hours. It started 30-45 minutes after taking the drug. I lost one day entirely, I have no recollection of it at all. For another 24 hours, everything smelled rotten. It took several days for my cognitive function to return to normal, and to be able to eat solid food. | This was after one dose. When I discussed it with my pharmacist he told me vomiting was a frequent complaint he got from patients regarding this drug. Vomiting is not listed in any of my drug reference books as a possible side effect. I had no fever, body aches, diarrhea or other sign of a viral illness. | F | 55 | 1 days | 8/20/2006 | 5 | RLS/PMLD | Naseau in the morning, severe at first. Doctor told me to hang in there as well as other family members taking it. WELL WORTH IT. | best thing I could have ever done for myself. IT CHANGED MY LIFE! | F | 47 | 23 months | 7/31/2006 | 3 | Fibromyalgia | At first the only side effect was lessening of appetite, which helped me lose weight - a good thing. Seven months later began having severe muscle and joint pain, especially in shoulders, upper arms, wrists and hands. | Mirapex was a miracle drug for me. Before starting it, I was able to walk only a block or two at 1.5 mph and only with a cane. Within a couple of weeks I was using the treadmill at a speed of 2.4 mph, for distances of 1.5 - 2 miles at a time. My energy level went way up, I slept uninterrupted 6-7 hours at night, was able to put away the cane and overall felt great for the first time since 1988. Seven months later the side effects started suddenly. I thought it might be a bad bottle of the med, but a replacement with a different lot number made no difference. I cut back from .5 mg 3 x a day to .25 mg 2 x a day per doctor's suggestion. Side effects are still there, but less severe for now, but I may still have to go off it completely as the severity seems to be increasing again. | F | 63 | 7 months | 7/27/2006 | 4 | RLS | Loss of appetite,but have a lowered metabolism therefore I am having a difficult time lossing weight. I have started coughing and severe itching on bottoms of feet and palms of hands (no rash). | I have had RLS for for several years and wasn't diagnosed until 1 year ago. Initially started taking .25 mg/day and the dosage worked beautifully for about 3 months and then I had to increase my dosage to .25 mg. 2X/day. The itching and cough are a bit annoying,but it outweighs the discomfort of RLS. | F | 42 | 11 months | 7/24/2006 | 4 | Dystonia/Fibromyalgia | Lack of sleep. Average 2-3 hours per night. Muscles still in knots afer 70 days. First round using Mirapex ... compulsive shopping on the internet. I couldn't sleep and the shopping mall (internet) was open 24/7. | My first round with Mirapex started w/ a 1/2 mg and increased by 1 mg every week to a final dosage of 4 1/2 mg per day taken at night. Other med was 25-50 mg of Doxepen. I wasn't sleeping but strangely enough funtioning ok. I went off the Mirapex cold turkey and on to another per Neurologist's instructions and went into a flare up. Started the Mirapex again and have found by taking 1/2 mg early morning,1/2 mg late morning and 1/2 mg early afternoon is enough to help reduce the "all over body pain". I sleep average of 5-6 hours even though it's not continuous sleep. Be aware of behavior changes. I feel better now that I've found the right dosage and time of day to take this drug. Still don't know what to do about the bloating | F | 48 | 4 months | 7/22/2006 | 3 | Depression | Sharp increase in IBS--daily diarrhea. Some OCD on higer dose (.25); went away at half that dose. | F | 28 | 6 weeks | 7/18/2006 | 5 | Restless Legs | CAUTION. The first night I took Mirapex, I cut my 0.5 mg tablets in half, to be safe. That night was the first time in my entire life that I didn't have to deal with restless legs. Four hours later, I woke up and could feel them coming back,so I took the other half, which worked immediately. The next day, I thought I was dying--I seriously considered going to the ER because of the vomiting and overall feeling of anxiety and awfulness. I thought maybe I was having a serious reaction. It began slowly wearing off though, so I didn't go. I swore off the drug, but several days later the restlessness came back, and I knew what relief the drug could give, so I decided to try 1/4 of the pill, and no more. It worked, and the next day I had a small amount of nausea, but nothing overwhelming. The dose had just been too high. Since then, every 3 days or so, I take 1/4. A genuine miracle drug. | I'm concerned about long term use, because of the fact that it increases dopamine--it seems to me that getting off after a long time could be a real problem. But anyone with restless legs understands the trade-off. | F | 50 | 21 days | 7/12/2006 | 2 | fibromyalgia | Started off on very low dosage. When I got to 50mg, experienced increasingly frequent palpitations. Withdrawal made them worse for a few days along with very vivid dreams. | Seemed to help the fibromyalgia but not worth the side effects. | F | 60 | 2 months | 7/8/2006 | 1 | Parkinson's | gambling | The gambling and mirapex connection is real. It happened to me. Don't take mirapex unless you are absolutely sure you are not succeptible to addictive behavior. | M | 47 | 2 years | 7/5/2006 | 1 | Parkinson’s Disease | The popular prescription medication Mirapex used to control tremors associated with Parkinson’s Disease and Restless Leg Syndrome by millions of Americans has been linked to linked to serious side effects including gambling addiction and other unhealthy compulsive behaviors. | M | 29 | | 6/30/2006 | 5 | Dystonia and Parkinsonism | Slight nausea, constipation, vivid dreams. | I take .25 mg 1x Mirapex along with Sinement 4x daily and Sinemet CR 1x daily at bedtime. I started about three years ago with sever muscle spasms in my legs, these worked up to tremors in my right hand, shoulder muscle pain, rigidity, stiffness on my left side, cogwheel arms, and nocturnal myclonic movements (punched myself in the nose a few times). After increasing dosages of Sinemet, the Mirapex has been added. This is a miracle drug for me. Nearly all the symptoms are gone, and I can lead a near normal life. I can live with the vivid dreams and slight nausea. | M | 45 | 45 days | 6/23/2006 | 5 | Fibromyalgia | Slight nausea for the first few days. Swollen abdomen, gas, bloating, some weight gain after 2 weeks. | Worth every side effect. I'll take it. This has been like a miracle. I've been diagnosed with fibromyalgia for 9 years and I feel normal again, like I used to feel. I never thought I'd feel this way again. And it's only been 2 weeks. | F | 45 | 2 weeks | 6/4/2006 | 5 | Restless Leg and PLMD | No bad side effects worth mentioning. In fact, a VERY BENEFICIAL side effect for me has been a slight DECREASE in my appetite, and subsequent loss of a couple pounds. YES!!! This does not mean I feel nausea or dizziness. I still eat three healthy meals a day. But I feel full longer and don't need cookies or sweets after or between meals. WONDERFUL !! Thank You Mirapex. | For me Mirapex has been a MIRACLE ! The PLMD has tormented me for the last five years. The movements are comparable to having a strong bolt of electricity sent through the leg about every 45 seconds. I am usually awakened at least a dozen times a night. By 6 AM I was so exhausted I could sleep for an hour or so, before getting ready for work. I have actually fallen asleep in my chair at work from exhaustion. How embarrassing. I also believe my PLMD to be partially responsible for the loss of a wonderful relationship a few years ago. My constant fatigue and irritability resulted in me becoming aggressive and argumentative toward her. How sad. I had been on Requip (1mg) for the last couple years, which helped about 50% of the time. I found myself having to take more and more of it just to stay asleep, and noticed the ankle jerking getting worse as time progressed. I stopped taking the Requip entirely. I went back to the MD last week and suggested to him we give Mirapex a | M | 55 | 7 days | 5/29/2006 | 4 | RLS | I do not sleep well at night. Also have sleep apnea and hypopnia. Very tired and drowsy during the day. Difficulty concentrating. I do not have as much energy as I would like, and have a difficult time staying awake at work when I'm using my computer (ever nod off and type 1000 x's?) My mood seems to be down most of the time, some times I am just plain crabby. | Neurologist prescribed Mirapex starting at .25 mg but told me I could go as high as 1.5 mg per day. Currently take app. .75 mg at night. It works well if I take it before eating dinner. Usually find that it doesn't have much effect if I have had a meal first. My doctor put me on Celexa for anxiety and to help with my sleep disdorder. Seemed to work very well, until the insurance company switched me to generic Celexa. All benefits vanished, so I quit the generic. This may be part or all of the reason for the irritability, but loss of sleep and drowsiness must have a part, also. I have been thinking of trying ReQuip, but one of it's side effects is drowsiness. May not be a good idea. I also take 160 mg of Diovan for moderately high blood presssure. I have a CPAP, but rarely use it due to mask discomfort. If I could wear it regularly, it would probably help. | M | 52 | 4 years | 5/21/2006 |