MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  parkinsons disease I have had bouts of severe shaking as well as times where I have had difficulty speaking and incidents where I was falling down M 29 7 days
2/8/2005
 3  parkinsons disease I have had bouts of severe shaking as well as times where I have had difficulty speaking and incidents where I was falling down this medicine has some effect on controlling tremors but I still have some severe shaking during the day. I am very young and this has been very hard for me to deal with. Sometimes I do not know what to do with myself. Depression has been very bad. I lost my job do to this and It makes things so much more complicated because i now have to beg for medecine from the free clinic and charity. I would like some insight from some of you to tell me how to deal with this. M 29 7 days
2/8/2005
 2  Fibromyalgia neurological twitching I made 2 attempts to try Mirapex. Both were terminated within 48 hours due to severe side effects. During the early hours of the 2nd attempt, hives, itching and rash resulted in my needing to immediately discontinue using this medication. Mirapex did seem to lessen the constant twitching. Unfortunately, the side effects made it intorerable to continue taking this medication. F 53
2/8/2005
 4  RLS It helps with my RLS, but so far I've had increase the dose because of ineffectiveness after a period of time. F 49 17 months
1/25/2005
 5  Fibromyalgia Can't eat but taking them with food lessens the nausia. Periods of being very sleepy during the day. This has made a big change in my life. I am so much better after 7 weeks of taking Mirapex. Wish I had known about this medication earlier. I am sleeping longer, my TMJ pain is gone, my IBS is gone, and I am more active. I feel much better!!!! F 57 7 weeks
1/20/2005
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 1  RLS Abrupt awakening very early in the morning (usually around 4am) and then later more symptoms started that may have been due to Mirpex or may have been from lake of sleep; ankles, hands and fingers swelling; falling asleep during the day; clenching teeth at night; shortness of breath; weight gain Could not get a doctor to believe that my smptoms were related to Mirapex since everyone raves about it for RLS but finally a sleep doctor agreed to switch me to Requip and life has done a 180 for me! F 44 18 months
1/17/2005
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 1  RLS Extreme nausea and dizziness. I started taking .25 mg and it didn't seem to help me sleep any better. In fact, it kept me awake at night so I was still tired during the day and I was extremely sick to my stomache and dizzy. When my dosage was lowered I still was having the same problem. I was just taken off of it. I refused to take it! Now my doctor is going to try something else. F 32 3 weeks
1/11/2005
 3  RLS extreme drowsiness during the day I take 1mg mirapex prior to bed together with clonazepam and temazapam. I am trying to get off the latter 2 drugs. At the 1 mg dose, mirapex helps me sleep and eliminates pain from legs. Howev er, I wake up like a zombie. F 52 1 months
1/10/2005
 3  restless foot 42 2 months
12/23/2004
 5  Parkinson's / suspect Fibromyalgia Water retention / wieght gain / loss of consentration / falling asleep while driving / sleeplessness Mirapex was prescribed for Parkinson's. I had to stop taking Mirapex when side effects became worse. However, Fibromyalgia like symptoms became MUCH worse without Mirapex. I would really like to see more people try Mirapex for Fibromyalgia. F 50 8 years
12/8/2004
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 2  fibromyalgia Nausea and loss of appetite. Taking it with food seems to help the nausea, but not the appetite problem. Talk about a vicious cycle! Don't see much, if any, improvement with this med. I still hurt as much as ever and still have non-restorative sleep (and horrible fatigue). I am no longer sleeping all day and I'm sure it's the mirapex, but now I'm awake and in pain instead of being able to go sleep through it. I'll give it until the refills are gone and then go on to see what the next experiment will be. F 39 1 months
12/8/2004
 1  Parkinson's Hallucinations, agitation, insomnia F 70 2 days
12/7/2004
 1  RLS Exteme mausea and vomiting that kept me up all night when I increase dose from .125 to .5. Did not help my RLS at either dose and made me sicker than I have ever been F 52 1 weeks
11/24/2004
 3  PLMD Initially while adjusting my brain felt Took Sinemet several years. On Mirapex over a year. Couple months ago went for weeks sleeping 2-4 hours a nite. Has improved again, 4-5.5 hours is norm. Take 1.5 in late eve and another at bedtime. My PLMD has progressed to flailing wildly even when dozing or just relaxed. Reluctant to switch meds due to torment during transition. F 53
11/18/2004
 4  Parkinson's Disease Seeing yellow spots occasionally. Increased pain perception. Itching. Nose-bleeding Helps diminish l-dopa induced stiffness, thus lessens muscle pain F 49 12 months
11/15/2004
 3  parkinsons F 57 7 days
11/8/2004
 5  rls None so far rls episodic for 12 years or more- the first night I took mirapex I slept all night ( that was the first time in over 6 weeks) believe me I am in awe of the results just praying for continued good response F 59 5 days
10/29/2004
 3  RLS Initially, few side effects. After some time: insomnia, strange thought patterns, augmentation of symptoms, rebound of symptoms, being cold at night, It was great in the beginning. As time went by, I had to increase my dosage. Then the side effects started. Eventually it stopped working on the PLMs, even with an increased dose. Side effects after 2 years were too much and have stopped taking it. F 45 2 years
10/28/2004
 4  Motor control & cramping in feet None So far so good !! F 43 5 days
10/21/2004
 4  parkinsons none yet F 48 10 months
10/2/2004

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