MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  parkinson's disease It started off slowly, but my neurologist warned me that it could happen. I experienced severe hypersexuality, Manic depressive behavior, OCD, gambling, overeating, sex phone calls, paranoia .... My life is turned upside down. Things got so bad I considered committing suicide. I drank and smoked pot to try and feel better, but it only made things worse. If you are young and taking this drug for Parkinsons ( I took 8mg a day.) STOP NOW. It almost cost me my life, my wife, my family and my job. M 50 8 years
9/13/2008
 2  RLS Insomnia, running thoughts, brain fog This medication was very effective for the RLS but at the price of insomnia. Expiriencing 1-2 hours of sleep a night, running thoughts all night, morning fog and difficulty concentrating. I was hopeful the side effects would lessen once I was used to the medicine but it only got worse. M 42 10 days
9/11/2008
 2  RLS Very dizzy all day long. Just need to turn my head. Weight gain 20+ lbs in 3 months. Forgetfullness. Depression. Muscle aches. I thought that the dizziness was my only side effect and it drove me crazy all day long. Everytime I turned my head I could feel my eyeballs bouncing back and forth. My husband didn't want me to drive anymore which was an issue with me. But I had also been gaining weight very quickly but thought it was from a depression medication I was taking. But I still continued to gain after stoping that drug as well. I have also been very forgetful to the point that I felt like I was losing my mind. Had some very embarrasing situations where I couldn't hide my memory loss. I have been having muscle aches as well and Im not sure if its from the drug or not but have a hard time getting out of bed in the morning or when sitting for a while. I feel so much older than I am. I have chosen to stop the Mirapex to see if I lose the side effects. It didn't help all that much anyway so the side effects arn't worth it to me. F 42 3 months
9/9/2008
 5  RLS I have had no side effects from this medication. Mirapex has been a life saver. I previously took Requip which worked for about 6 months, then my physician gave me Mirapex... I am taking half of the .125 mg in the evening. It takes a couple of hours to start working but my legs are relaxed which ables me to get to sleep. F 53 3 months
9/8/2008
 5  Severe RLS Nausea, I was able to fall asleep quickly but was WIDE awake w/i a few hours. I became so sleep deprived that it started to effect everything,joint pain, sinus congestion, some depression.I have beentaking this med 2007.I have gained 52 lbsMy Dr. set me up for a sleep study that states that i breath just fine,But my heart range is 52 up to123. and that i sit up quite a few times an hour. I probaly woul'nt had to do th sleep study if I knew about all of reactions. I too am starting to gamble. I have neverbefore I does a great job of controlling my severe RLS F 44 2 years
9/8/2008
 2  RLS Had trouble sleeping, felt bloated all the time, constipated, headaches and it didn’t help the burning, tingling pain at all. Took .25 for 7 days then increased to 2 pills at night. Have not had more side effects but still have the ones listed above. And yet still no relief. I just am glad I didnt have some of the really bad side effects that I read about on this site. F 45 10 days
9/7/2008
 5  Tremors Impulse Control Worked a wonder on my familiar tremor... however I became very obsessive compulsive. M 32 4 months
8/31/2008
 5  Restless Legs Syndrome None that I can directly attribute to Mirapex It is sad to read all the negative reactions, because Mirapex has been nothing short of a miracle for me. I have very severe RLS, (everyday, many times during the day/night, causing sleeplessness every night, most of the night). I take .125 mg (the minimum dosage), at about 8 p.m. and it continues to be effective, taking about 2 hours to "kick in." When I am going somewhere requiring me to sit (concert, movie, etc.), I take it about an hour before the event so that I know I will be able to sit through most of it. F 60 5 years
8/23/2008
 4  Restless Legs Pain in legs and feet, Obsessive Thoughts, Obsessive eating, extreme lethargy, morning hangover, Sleep is all I think about. Completely stopped severe RLS symptoms, complete lethargy not worth it though. M 39 30 days
8/15/2008
 4  Parkinson's,Dystonia,RLS Mirapex works well for my symptoms -tremors,dystonia,stiffness,etc. My main complaint is the weight gain of 35lbs in 2 years. If I sit down, I am ready to fall asleep, but at night, I am wide awake. I generally sleep from 3am to 7am. I tend to be foggy, but it may be sleep deprevation. I make sure to take it with food. I don't eat much during the day, but binge after midnight. I also am compulsive about computer-games/research and shopping at Thrift stores. I have managed to fill up most of my horizontal surfaces with vintage pottery. It works well for me, but I may have to switch drugs due to the weight gain. Works great for me. F 56 3 years
8/15/2008
 1  Restless legs Hives, itching, poor sleep, but the worst thing was the deep depression with paralyzing sadness and a feeling that my heart was breaking. I am so glad I figured out that it was the Mirapex causing my depression. I was almost ready to go back on Effexor when I decided to just stop the Mirapex instead. I felt better in one day and, after two day off of it, I feel fantastic. I still have the RLS, although it has gotten better as I get my ferritin level up. In the case of Mirapex for RLS, the medicine is worse than the disease. At least with RLS, once I get to sleep, I sleep well. With Mirapex, you wake feeling like you haven't really slept, which might be what causes the depression. Lack of sleep shrinks the amygdala, the part of the brain that processes emotion, and small amygdalas are linked with depression. F 51 5 weeks
8/9/2008
 3  RLS Have been taking Mirapex for approx. 2 years. I thought I was crazy until I read these comments and I see so many similarities. I have severe muscle pain and weakness, the sensation of something brushing against my arms and legs, tapping my teeth, constantly moving my toes,neck pain, inability to sleep, nausea, increased interest in shopping although not excessive. It has definitely helped the RLS but I am going to find an alternative treatment. F 60 2 years
7/31/2008
 1  Parkinson's disease Manic behavior, compulsive gambling, binge eating, swollen legs and feet, insomenia--this drug has ruined many, many lives. Be very careful! I know of a doctor, several attorneys, a nun, ministers, bankers, policemen--all of whom have had their lives ruined by this drug and the manic, compulsive behavior it causes. It is time for Boehrilnger Ingleheim to do the right thing by these people whose lives have been devastated. These people's suffering has spared someone else from enduring the hell that Miarpex can cause. Beware! I never thought it could happen to me, but it did. Remember that this is a medicine that affects your brain! M 61 5 years
7/27/2008
 3  RLS Anxiety, lethargic, low energy especially in the AM,paranoia, a need to go back to bed after being up in the AM for an extra 20-30 minutes,memory loss, weight loss, dry mouth,ankle & hands swelling, lower motivation. AM hangovers. The side affects took time to develop and became much worse the second year. My sleep has become deeper and slightly longer, 5.5 to 6 hours. Minimal S/S of restless legs in the evening. Falling asleep early in the evening. M 70 2 years
7/19/2008
 2  restless leg syndrome intense, weird dreams; increase in anxiety, morning 'hangover', constipation, profuse perspiration and night sweats It certainly fixed the itchy-twitchies in my legs but the dreams were disturbing. I take a low dose of Zoloft for pre-menstrual dysphoria and this drug seemed to work against the beneficial anti-anxiety properties of the Zoloft. All in all I'd rather have itchy legs - will try homeopathic remedies, up the iron intake. This drug just made me feel too weird! F 48 15 days
7/14/2008
 3  RLS Has radically altered my sleep patterns. Before taking Mirapex my lifelong sleep pattern was difficulty falling asleep (often 2-3 hours), but then sleeping through the night afterwards. On Mirapex, I can fall asleep very quickly at night (as well as during church, in meetings, watching TV or in Movie Theatre), but generally wake up at 3-4am and can't go back to sleep. Have also had a lot of sticky phlegm in throat that stated about the same time as starting mirapex, that contributes to snoring and waking frequently at times. Have also seemed to have struggled more with some compulsive behaviors (primarily eating) that may be related. Mostly controls RLS symptoms. M 45 18 months
7/10/2008
 3  RLS Nausea, sleeplessness I'm taking .125 (I think) as needed. It does knock down the twitching, although not completely. The nausea the next day ruins it for me though. Since I don't take it regularly (perhaps once a month or even less), I don't suffer from the other side effects mentioned. M 45 2 years
7/7/2008
 5  Parkinson's Disease Vivid dreams, occasional brain fog I have had Parkinson's Disease for 7 years. Including DBS, Mirapex (1 mg. 3 x day) is the first drug that has stopped the tremor and given me back a mostly "normal" life. I take it in combination with Amantadine. I was shocked to read the reports in this column. My experience has been positive. F 60 1 days
6/28/2008
 5   Nasal stuffiness withing 30 minutes of taking it. Sleepyiness after taking it, plus need to sleep about 2-3 hours extra a night. Possibly loss of focus during the day. It has truly been a miracle for me. It has given me my life back. I had severe RLS for 25 years and suffered about 12-15 hours a day. F 44 12 months
6/27/2008
 5  RLS Insomnia I had terrible pain and discomfort every night from RLS, I would even have leg shaking during the day. Mirapex has been a wonder drug for me. I tried both Mirapex and Requip and I found Mirapex to be much more effective. F 43 6 months
6/20/2008

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