MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Full body nerve pain and fatigue Unfortunate increase in spending for my favorite pastime, designing and selling jewelery. Manic behavior; force myself to go to bed at 3:30AM. Weight gain due to being awake 20 hours a day. Family mad at me all the time, would rather bead and shop than keep house and cook (go figure) Taking it over 2 years, can't stand to quit due to return of intolerable fatique (too tired to breathe...head injury as a child) Would like to hear from anyone learning how to deal with changes in their personality. I enjoy the creative part of my brain being more productive but in this economy I need to sell more of what I produce in order to pay for the urge to design all the time...which, of course, requires supplies. I feel so much better that even 4 or 5 hours of sleep, which causes a different, common kind of fatique, is not enough to get me to go off of it. I could, it is not adictive in the usual sense. F 63 900 days
1/16/2009
 5  rls None that I can identify I can finally sleep, am on lowest dose and take about 2 hours before bed....been on for 5 months and at last I am sleeping...after 12 years of struggling....does not work as well if one has alcohol in the evening or at dinner...but I am only concerned that after awhile the dose will have to be increased...I started by cutting pill in half and now need the whole pill..... F 68 5 months
1/12/2009
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 4  rls none noted F 56 3 days
1/6/2009
 1  Restless Legs Sydrome I started taking this drug in August 2004 weighing 140 lbs (5'8"). It worked miracles for my RLS symptoms. I experienced some augmentation, but was willing to live with it. By April 2004 I weighed 148 lbs, but didn't think to attribute the gain to Mirapex. By January 2006 I weiged 160 and in January 2007 173 lbs. That's a 33 lb gain in 2 1/2 years. I work out a lot and watch my weight, but still it's extremely hard to lose the weight. I have also had weird "spells" that neurologists think are partial seizures, but I think these are not seizures but altered consciousness from Mirapex. I also have developed a terrible short-term memory. I have a Ph.D. in philosophy. I've written three books and I'm very accomplished, so I couldn't understand how all this is happening to me. Now I think it's the Mirapex. The only other drug I take is synthroid, but only for the past few months. I'd like to find some good alternatives to deal with the symptoms of RLS. Next I'll explore acupuncture. F 48 4.5 years
1/5/2009
 4  RLS & PLMD I experienced absolutely no negative side effects from taking this medication. I am currently taking .25 mg/day in the early evening of Mirapex. When I first started taking Mirapex, the first week was phenominal. All RLS / PLMD symptoms disappeared immediately, and I never slept so well in my life. However, like most RLS / PLMD medications, over time they tend to lose their strength, and it seems as if the RLS / PLMD symptoms find a way around the medication. I have currently been taking Mirapex for 6 months. Although it still does provide me with the benefit of lessening my symptoms and the rate of occurrence, my RLS and PLMD has found a way to fight through the medication. I have gone from no symtoms of RLS at the beginning of taking Mirapex to about 4 episodes per week now while still on Mirapex. It isn't the solution drug, but in my opinion, it does have a benefit. M 38 6 months
12/15/2008
 2  PLMD clinically documented constipation, severe unrelenting temper tantrums, OCD type behavior, sensory issues, difficult to wake up in morning, possible visual hallucinations It was definitely causing terrible tantrums over trivial things, i.e. her pants didn't fit right or we were out of peanut butter. She had a terrifying hallucination this morning even though she has been off of it for a week. I could not take this drug myself, but have no memory of the time in which I took it. I definitely do not recommend this drug for people with mood disorders, either potential or diagnosed. F 7 21 days
12/7/2008
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 2   Severe weight gain, compulsive eating, twitching, fragmented sleep, waking up after several hours of sleep, nearly impossible to drive during the day works ok for the restless leg, but I am now pushing 300 pounds, and can't seem to stop eating. F 34 2 years
11/24/2008
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 3  p.d sleepless nights get stressed easy short tempered F 60 7 months
11/15/2008
 1  RLS RLS After the second night of taking Mirapex, my legs quit aching and I thought it was a miracle drug. Around the 3rd month, I developed a sudden extreme pain in my kbee, It felt like a knife had stabbed my knee. I cyt the dosage in half, and the pain stopped as suddenly as it has started. A week later, the pain was back with a vengenance, I no longer take the Mirapex, but my knee pain remains. Sometimes it is so bad I just want to scream. I no longer sleep at night- the pain keeps waking me up. The last couple of weeks I have had to move from the bed to the recliner halfway through the night to extend my leg to relieve the pain, My husband just rolls his eyes when I tell him I know the Mirapex caused these problems. I know in my heart that the nedication is to blame F 52 3 days
11/14/2008
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 1  RSL Have taken for two months. Have gained 5 pounds due to complusive eating due to being constantly hunger; have very vivid dreams that seem real when I wake up. Very disturbing. I stopped taking the drug yesterday. Will write back in a month to report how my legs are doing. F 59 60 days
11/9/2008
 1  RLS Mirapex initially worked, but overtime it exasperated my symptoms of RLS, thus my dosage was gradually increased over 10 years along w/the severity of the RLS symptoms. While on Mirapex, I had increased & chronic headaches, weight gain, edema, OCD, manic-depressive disorders, memory loss, unable to stay on task, impaired normal thought process and reasonable decision making process, restricted learning capabilities, obsessive spending on Ebay, and poor behavioral habits. I am convinced that while on Mirapex this drug cost me friendships, job promotions, respect in the workplace, and reduced my quality of life to a point of wanting to take it. This drug almost cost me my job and a very loving family, thank God I did not. After learning of the side effects associated w/ Mirapex, I stopped using this drug. Initially my RLS symptoms were extreme & server, after about 4 weeks, these symptoms subsided and now my RLS symptoms or very minimal and controllable. The side effects that I was experiencing have drastically subsided or gone completely. It is my hopes that this drug will be taken off the market, and for no one else to have to endure this fate. M 49 10 years
10/29/2008
 1  RLS I was saddled with headaches, foggy brain, and weight gain, while the Mirapex did not help my RLS. Upon quitting use, my headaches are gone, my head is clear, and I am once again losing weight! M 48 4 months
10/24/2008
 1  Fibromyalgia I started having severe twitching/spasming of legs & arms. At night, I would just be falling asleep and my whole body would spasm and wake me up. I also became obsessed with a game that was on my cellphone. I became paranoid and I had bizarre, vivid dreams. It has been 3 - 4 years since I took Mirapex and I still have the twitching going on - though not as severely. Once I got off the drug, the desire to play games on my phone vanished. (I have never been a video game player.) This is a scary drug that impacts cognition. I'm amazed it is still on the market. F 55 30 days
10/14/2008
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 1  parkinsons At first, it worked well, I could sign my name again and the tremors stopped. However, I had nausea, vomiting and fatigue, which I hoped would clear up in time. Instead, these symptoms intensified over the next 5 months. I was also experiencing increase depression and anxiety. I was napping 3 times a day and still sleeping all night. The first day I went off, I had amazing energy, no upset stomach and could eat chocolate again. The second day off, I did have some withdraw symptoms, like muscles aches and fatigue. These past. For me Miraplex goes on my list of evil drugs, along with Effextor. For weeks my husband told me the problems were due to the Miraplex. I couldn't believe him. I think the drug clouded my thinking ability. F 49 6 months
9/29/2008
 3  Fibromyalgia I talked to my Doctor about taking Mirapex after reading up on the pro's and con's of the drug. I wanted to get off soma and ANSID's that don't agree well with me. I am on a low dose right now. Since the first day I started the drug I have a very hard time falling and staying alseep. my eyelids twitch and wake up with an upset stomace. I haven't had wieght gain this far. I hope it stays that way. My PCP recommeded Lyrica and I didn't want to go on it for that reason. I do how ever believe I am getting a bladder infection. and do have a racing heart through out the day. I have been sweating. For the most part I rather be on this then other alternitives ask me in a month to see if i still feel this way. I don't want to increase the drug anymore, but I rather not be in pain. i am currently in school for medical assisting and I do also find it hard to get my words out since i began this drug, it's not bad enough to upset my GPA to much this far. But... i will let you know if i find it do F 23 3 weeks
9/28/2008
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 5  RLS At first, some nausea and vivid dreams, dopiness after it kicks in (which is good because I can sleep!). Twice at the beginning, I suddenly almost fell asleep driving. That scared me but passed quickly. Hugely effective. I used to wake up once an hour all night, now only once or twice. It worries me that after a month, I had to triple my dosage--suddenly when it wore off, my restless legs were 100x worse than ever before, could hardly sit down, arms just like RLS too. Is there a rebound effect? Will I need to keep increasing the dosage as I get used to it? F 47 60 days
9/18/2008
 1  restless leg syndrome I vomited after about two hours and the medicine did absolutely nothing for my restless legs. I have severe RLS. It occurs every time I lie down. Klonopin has not worked and the only meds that have worked are Hydrocodone. I'm about to try Requip. F 51 1 days
9/18/2008
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 2  RLS Relieved the RLS but started making me jittery at night, as if I'd had an entire pot of coffee before bed. Also had "hot flashes" during the day. Interfered with my sleep worse than the RLS did. For about a day it was ideal between relief from RLS and any of the side effects but after the third day of the higher dose in the sample pack I had to stop. Starter dose didn't do anything. Will be trying Requip next. If the side effects weren't so bad, I'd stay on it but the main reason I need the relief is the RLS interfering with sleep. Daytime RLS symptoms are tolerable for now. M 44 7 days
9/16/2008
 5  restless legs unsure since I am taking other medications such a blood pressure.Tremblings?/overall weakness? M
9/13/2008
 1  Parkinson's This drug causes compulsive sexual behavior. Twice it has cost me time in jail! Under un-watchward physician care and mostly from the use of this drug that was prescribed to me my my doctors. It has cost me two felony charges and 9 months in jail! It has cost me a small fortune, and my life has been nearly ruined. I can't recommend its use. Avoid it! I feel that the company has been more than negligent in not warning the public or physicians properly of its dire effects on people, especially with a high suceptability to the adverse effects of oral medications. I was prescribed this drug twice by doctors(neurologists-so called), and twice in a very short time unbeknownst to me I began behaving in compulsive sexual way hughly untypical of myself. I ended up breaking the law and spent time in jail and lost virturally all I owned! I was living in a place where there were few people whom knew me well enough to properly detect that something was very wrong and that and inept "doctoring" and the very compounded effects of a very dangerous drug, -specifically MYRAPEX- I found myself in jail and a having become so compulsive in my behavior from the side effects of this drug that I became criminal in my lifesyle and mental state of mind. This drug is dangerous. The makers of MIRAPEX owe me big time! They taken no steps to comp M 52 2 times
9/13/2008

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