MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22


RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  rls I have bad compulsive disorder for gambling. I need to change mirapex to something that wont cause complusiveness.but it must work for my rls thank you 69 1 days
60 mg day
11/7/2014
 5   After 40 yrs on all types of medication for depression mirapex has finally helped me with my depression. Only side effects are swollen ankles and stiff lower legs ( arthritis like) to the point that I have trouble moving after being in any sitting position and begin to walk. When walking notice some stumbling and stiffness in writing. M 68 3 months
.25 MG 1X day
10/10/2014
 1  rls after 1 month started getting rls10x worse..during the day...in other parts of my body...twitching in the face, legs all over horrible...tried to taper off and had terrible withdrawal spent all night pacing for 3 days before giving up.. F 60 4 months
.125
7/24/2014
 1  RLS Addiction to gay porn, spent all day sleeping as dreams were so much better than my real life, started smoking, scratch cards, short term memory problems, lying, erectile dysfunction, compulsions, two pulmonary embolisms pretty much screwed up my entire life. Still get no enjoyment from anything just waiting to die. Still erectile dysfunction although addictions have gone but short term memory rubbish. Wish I had never seen the news article and asked my doctor for it. Cured my RLS on day one with half dose, but side effects, and on-going side effects are life changing. Probably worth it for Parkinson's patient as they are going to die anyway. Cured RLS by taking 30mg Codine Phosphate Hemilhydrate/ Paracetamol 500mg (called solpadol) before bed, no side effects as yet. M 40 2 years
.5mg 1X day
1/13/2014
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 5  RLS I had RLS so bad. My Dr prescribed Mirapex, 0.25 at first and now I'm taking 0.50 every night. I'm really amazed that Mirapex has helped me this much. I have not had any symptoms of RLS since day one. I have had no side effects. I've actually lost almost 30 pounds in 4 months. F 42 4 months
0.50
12/13/2013
 4  RLS constant fatigue..memory loss, compulsive gambling, depression it worked very well at the beginning, now if I'm late taking it I suffer for hours until the drug takes effect. I realize that it's just not working as well anymore and hope that there's some thing else I can try. I'm very upset about the gambling side effects.... totally irresponsible and uncontrolable.... it just not me! F 61 10 days
50mg 2X day
11/15/2013
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 1  Restless Leg Syndrome Severe paranoia and paranoid delusions including shooting at neighbors believed to be hurting me; compulsive behavior in terms of shopping, hoarding, eating; impulsive behavior such as acting without thinking of the consequences; lost career; was arrested for the first time for a felony in my 60s; detached retina; had pneumonia including hospitalization about 9 times; was hospitalized three times for syncope; experienced excessive sleepiness during the day and had difficulty driving and staying awake; herniated disk (L4-L5); stenosis; curved spine; problems breathing and weezing that mimicked asthma; Mirapex pretty much ruined my life over the course of 11 years and the doctor failed to recognize that the Mirapex was causing problems. The symptoms of Mirapex resulted in countless misdiagnoses of other conditions such as narcolepsy and asthma, and it did untold amounts of damage to my eyes and teeth. I had a detached retina in which I lost half of the sight in my eye; I had three tooth I believe it is criminal for doctors to prescribe a dangerous drug like Mirapex for a relatively benign condition like restless legs. The drug companies involved have made out like bandits by extending their patent to restless legs when the patent for its use with Parnkinson's was about to expire. F 61 11 years
2 MG 1X day
9/10/2013
 1  Parkinson's Disease I lost myself, I began telling stories that were not true and getting deeper into a fantasy world created in my mind. Became easily agitated and aggressive. The stories didn't need to be told and I had no desire to make up a story but here I am telling this story without the ability to stop. Grandiosity became a real issue with me. Even if you're an intelligent person, this drug doesn't care, it will make you do the things you know you have no business doing and would never have done before. M 56 8 years
1.5 1X day
8/13/2013
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 1  rls took this drug 1 night for rls and woke up with severe stomach pain, then proceeded to throw up for 12 hours, also had a bad headache. after reading other peoples problems with this drug i am glad it happened on the first night. will have to figure out how to control rls by myself F 53 1 days
1.5 1X day
8/2/2013
 1  Parkinson D I could not stay awake, I had double vision and could not at times focus my eyes to save my self and a increasing RAGE that made me almost kill myself more than once I am not sure which was worse the drug or the PD but I am off of it now and after a month on my new meds I feel more like my old carefree self and am beginning to regain my hippie like self again YEAH for me I would never tell some one to take this drug ever F 52 3 years
.75 3X day
4/9/2013
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 1  RLS I would never recommend this drug to my worst enemy. It worked really well for a few years, but then I began augmenting, had horrible RLS, and had to quit cold turkey. 3 weeks of pure hell...now I know what it is to go through withdrawal from a powerful addicting drug. Stay away. F 62 10 years
1 3X day
3/14/2013
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 1  RLS I took my 1st dose of Mirapex last night and it made my symptoms worse. Not only was I constantly moving my legs, but my feet were burning and the skin on my feet were so sensitive it hurt for the sheets to touch them. I didn't get any sleep last night. I am so tired of this. I'm sitting at work now and only slept in about 15-20 minutes spurts for about a total of 1.5 hours. My body is getting wore down. I just want to be able to sleep and for the past 4 months I haven't gotten any sleep. Last night was by far the worse though. I don't know if I should take the Mirapex again tonight or not. I called the doctor and he said to take 2 tonight instead of the one. I don't know what to do. F 28 1 days
0.125mg 1X day
2/12/2013
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 4  Restless Leg Syndrome Compulsion to purchase items in general but I can control it. I have severe RLS so that without drugs I stay up 24 hours a day and spend most the time pacing because I cannot even sit down. With Mirapex taken at night and other medications during the day I am able to lead a normal life. Without sleep I cannot work or enjoy life at all. Mirapex has been the only drug that allows me to live a good life. I probably should give it a 5 but I am giving it a 4 because of the fact that it gives some people compulsions such as I have with it. M 57
.50 mg 1X day
12/16/2012
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 1  restless legs on this several yrs, Doc.s increasing the drug, and # of times he was taking it, with NO CONSERN.looking back, urine prob, falling alsleep while driving. memory, depression, ocd, shopping, gambling, 70,000. to 100, 000. gone. more if adding the shopping, paying for sex, tried to kill self, ended up in mental hosptial. was also beginning to drink, and smoke again, even with copd. horrible drug, been trying to get help from Dr.s for most of this yr. zip! began running tests with neuro dr. when he bought a gun, and tried to kill himself. this is a good, hard working, honest, loyal, husband before this and have watched him become "someone else" Possible his water retintion problems, are also all/part caused by this as, since off it and home 2 weeks, he is having no problems at all. breathing is better too. no OCD, just feeling very guilty and trying to deal with what he has done. This should be taken OFF the market. I am reporting to FDA, and going to see about legal rights Had 2 drug changes, one in Hosptital, that was not holding the RL. 2nd drug is new! Horizon ??? or something that makes me think of that. 3 nights of horrible, uncontrolable shakes, kicks, twitches of whole body. huge workout, of all muscles, sweat pouring off. fell, 2nd time. tried massages, with different things, hot bath, heatpad, cold, muscle relaxers. took 3 days and nights, before we got any sleep. then started getting better. not perfect, but good. M 69
1X AN
12/6/2012
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 4  RLS Initial nausea at first. The first morning I thought I had the flu. I reduced my intake to a quarter of a pill and gradually worked my way up to half a pill a day. Nausea subsided with no other side affects. My doctor prescribed Mirapex after I developed minor anaphylaxis to Ultram. The withdrawal from Ultram was excruciating. Mirapex has been a lifesaver for me and has practically eliminated my RLS. I haven't developed any of the other side affects to include gambling or compulsion. I think these person specific. Everyone reacts differently to medications. M 41 2 months
,25 MG 1X day
11/22/2012
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 5  MS induced RLS I am not aware of any side effects. Very surprized reading all the bad reactions - I guess I am VERY lucky. Mirapex has been a godsend for me. I don't think I could function without it. Started 5 yrs ago taking as needed but now increased to daily. Of all the meds I take, I think Mirapex would be the last one I would give up. F 60 5 years
0.50 mg 1X day
11/13/2012
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 1  rls Unable to function,confusion,flu like symtoms. you now have rls in your intire body.This drug is not for rls. It did nothing to help only made rls symtoms worse,.I took the extended release.What a mistake.It takes a long time to leave you system. This is a terrible drug.You are home bound and ready to lose you mind while waiting for this med to leave your body.What ever you experience from rls is nothing compared to what this drug does to you. Please don't try it. AND IT DID NOTHING TO HELP RLS. F 69 1 days
.375 1X day
11/13/2012
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 2  Restless legs It doesn't stop my restless legs, even though my doctor said to take it with Sinement 25/100mg, it still doesn't help me.My doctor told me this week when I'm finished with the script. to not take it anymore, when something isn't helping me there's no reason to continue taking it.So - when I finish the bottle of mirapex, I won't renew the script,& try something else. I haven't been able to sleep more than 1 to 3 hours nightly, & that's not good for me. Sorry it just doesn't work. Goodbye F 85 6 months
1.5
9/9/2012
 1  pk Such a terrible drug. Extreme halutionations. Panic. Overwhelming themes, such as, lumber being stolen to be processed, visions of imaginary men 14' tall. Confusion. Sleeplessness. Not eating. Obsessed with images and themes that seem so real. M 62 10 days
5mg
8/21/2012
 1  Parkinsons My mother has been taking Levodopa for 4 years, but since she was given also Mirapex, in April 2011, experienced extreme fatigue, too much sleep even during the day, personality changes, vivid dreams, allucinations. Now she's trying to come off it, following a neuro doc's advice and is going through hell, she cannot sleep at all, she's got panic attacks and is very much distressed. Angry with the GP who prescribed it to her saying it would help... Awful medicine due to side effects and extreme difficulty to stop it: no benefits for the patient, as far as I could see. I hope it will be removed from the market. Wonder why the doctors keep on prescribing it, without warning of what kind of medicine is this: highly addictive and with no evident improvement for the Parkinsons' sufferer. F 89 14 months
1X day
8/12/2012
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