MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  parkinson's Very mild nausea as I titrated on. Now at 1 mg, 3X daily. Some daytime sleepiness if already short on sleep. Occasionally feel mentally "foggy", but not if I take ginkgo biloba (1 cap) in AM. BIGGEST SIDE EFFECT--DRAMATICALLY INCREASED LIBIDO!! (Not considered a problem!) Mirapex definitely works for me! Neuro doc charts decrease in all symptoms. F 48 7 months
2/4/2007
 1  parkinson hallucinations....seeing things memory lost completing this about my mother....drug is dangerous F 79 2 years
2/1/2007
 4  RLS & severe PLMD On 0.25 mg, I had nausea, dizziness, unsteady gait and horrific violent nightmares. On lower dose, I don't have any side effects and experience great relief. At first, the higher dose caused intolerable side effects, so I lowered the dose. Now, I take either 1 of the 0.125mg pills or sometimes, I'll take 1 1/2 pills. Both have been quite effective. I didn't know just how well Mirapex was working until I was switched to Requip....that was horrible!! On Mirapex, I'm usually symptom-free and along with a C-Pap machine (for sleep apnea), I'm actually sleeping well and feeling rested in the morning!! Also, I no longer kick my husband in my sleep!! F 46 6 months
1/24/2007
 3  Parkinson's Mild occasional nervousness, dizziness and hillucinations, mild nausea at the beginning, insomnia occasionally, I suspect it has increased episodes of irregular heartbeat I've been experiencing lately. Has helped with pain, flexibility and general mood but tremors actually seem to have worsened. M 61 3 months
1/13/2007
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 4  RLS No apparent side effects I am taking 0.25 mg. My wife reports that my RLS is reduced, but not eliminated. I notice a significant improvement in my sleep. Also have OSA and have used CPAP for 6 years. Between CPAP and Mirapex I have slept better in the last year than I have for decades. M 49 1 years
1/7/2007
 5  to hope it would stop aching legs Only brief nausea the first week of starting on mirapex. I have been taking mirapex for over 10 years. For me it was a life saver. With a very ill husband and maybe three hours sleep a night I was living in a sleepless daze. I was reading everything on line and in magazines when I ran across an article about mirapex helping rls. My arthritis dr. had received information from Mayo Clinic and prescribed it for me and it has helped me from day one. I never take it during the day and drive because of falling asleep side effects. So far it has helped me during the day until late in the afternoon and may have to increase to four .125mg pills instead of three .125mg in the evening two hours before bedtime. I now know I have had fibromyalgia since childhood and never had restless legs. I moved my legs because they ached not because of a creepy crawly feeling. F 79 10 years
1/4/2007
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 4  Parkinson's Disease Abnormal eating behavior(high appetite for food), Shakeyness and small hand writing have disappeared. Balance and walking is better and I have more energy. F 36 8 days
1/2/2007
 4  PLMD; severe sleep apnea Serious problems when I tried to cut down on the dosage -- went into severe convulsive spasms almost non-stop around the clock except when I was standing upright and walking. This lasted about 10-12 days until my physician ordered me to return to the mirapex three times a day (.0125 mg.) Like magic! The violent convulsions stopped immediately. This stuff is scarey but it works so well for PLMDs that I am willing to take it anyway. WARNING: do not decrease dosage without doctor's involvement. Other side effects, I suspect a shopping compulsion (few months duration, twice) plus I wonder about my slow and steady weight gain without increase in caloric intake. Never mind, I'll deal with it just so that I can sleep and live a normal working life. It works! It works! I can sleep! I can go through the day without snapping my head violently or twitching my torso so hard that I lose my balance. I can sit in church for a full hour and not look like a crazy person. I can keep my job. Never mind the few minor side effects, like augmentation and increased side effects when I tried to cut down the dosage.... I'll deal with that. F 68 17 months
12/31/2006
 4  RLS Vivid nightmares, compulsive shopping, inexplicable bloating and steady weight gain. The relief from RLS symptoms is wonderful; the other side effects are not. Catch-22. F 43 3 years
12/29/2006
 1  RLS uncontrolable mood variations; falling asleep without any warning, day or night; acting as tho the person was "high" The patient was my 17 year old daughter. She was suspended from school because the school had suspected that she was "high" off of weed...when in fact, she never smoked it. She lost her relationship with her boyfriend of 1 1/2 years. She doesn't even act like herself anymore. The doctor said to discontinue use of Meripex IMMEDIATELY!! F 17 5 days
11/29/2006
 5  RLS No side effects noted I take a lot of medications so it would be hard to single mirapex out. this medication has been a blessing sent to me. I just love night time now because I know that I am going to get sleep, and not be miserable with that crawling feeling in my legs. Be sure to get a ferritin level done. This also is a cause for RLS. Mine was low and along with Mirapex this helped. F 56 4 months
11/1/2006
 5  RLS No side effects noted I take a lot of medications so it would be hard to single mirapex out. this medication has been a blessing sent to me. I just love night time now because I know that I am going to get sleep, and not be miserable with that crawling feeling in my legs. Be sure to get a ferritin level done. This also is a cause for RLS. Mine was low and along with Mirapex this helped. F 56 4 months
11/1/2006
 5  RLS NO SIDE EFFECTS. It is absolutely wonderful to get a good nights sleep without having an attack of RLS. I can now go on trips without worrying if I was going to disturb others in the house with me walking the floors. It is a new lease on life for me. F 56 3 days
11/1/2006
 2  Parkinsons Horrific nightmares during the first 3-4 months (now rare, but still occur). Sleep disorder. Regardless of when I go to bed, rarely sleep beyond 0330. Am on only 1.5 mg/day. So far, don't think it's helped much. Right hand/arm/shoulder shake like a leaf in the wind when chilled or fatigued. M 66
11/1/2006
 5  rls a miracle indeed. taking the lowest dose 0.125 plus 5mgs of ambien and my life has totally turned around. no side effects at all! i wish everyone who is suffering without hope or professional assistance could find a way to try it. where we live, a prescription isn't required, so we read these posts and gave it a try. good luck to one and all and good sleep!!!!!! M 70 2 months
10/28/2006
 5  RLS Some nervousness, gas, weight gain. I used to consider myself lucky if I got 2 or more hours of sleep a night. I would be dragging myself around all day and sleep all weekend to catch up. I started the mirapex 3 months ago and now can sleep 6 or more hours a night. not quite perfect but I'll take it. The twitches in my legs are pretty much gone, but I do feel nervous and anxious when I try to sleep and that does keep me up a little. F 27 3 months
10/19/2006
 5  RLS After four years of taking the medication, I have just ow began to experience Nausea with a very high dose. Other than that, I can not say that I have experienced any other side effects that I know of. One piece of advice, never, ever take Benadryl or Phenergan without taking Mirapex if you have RLS. Both of these medications can increase RLS s/s to the most severe degree... This medication has changed my life. I began having very severe RLS s/s when I was in college. could not date, go to movies, or anything that was associated with night time activities. I worked as a night shift nurse for a few years to try to stem off the terrible feelings by moving around all night long. My doctor finally prescribed Sinemet and it worked for about 6 months and then augmented the symptoms of RLS to my arms as well as my legs. I was worse than ever. I tried Requip and had a very weird reaction to it called a dystonic reaction....Then they tried me on Mirapex. Now I can not live without it. I can sleep and if I forget the drug I am miserable. I don't mind the nausea at all, it is nothing compared to the misery of RLS. F 29 5 years
10/15/2006
 1  RLS I experienced great relief from the drug, but am now battling serious gambling issues, which are causing excessive stress in my family. I started out when a doctor FINALLY decided to treat me for RLS amost five yrs ago. None of the other doctors believed what I was telling them as symptoms. They continually gave me "pain killers" to put me to sleep. I finally got Mirapex two yrs ago. I started with one .25mg prior to bed, but have now worked my way up to 3/4 .50mg pills prior to bed to ease the twitching. The torture of the foot pain and lack of sleep has gotten much better, but I have now had to refinance my home to pay off all the credit cards I max'd out for cash advances to buy scratch tickets and lotto tickets. I tell myself how foolish it is, but then find myself at the counter buying them. I have even lied to my wife about my gambling. THIS IS NOT A DRUG TO BE TAKEN LIGHTLY!!!!!!! I am working with my primary now to get off of this and find a replacement drug. DO NOT TAKE THIS DRUG!!! THE SIDE EFFECTS ARE NOT WORTH IT!!! M 58 1 years
10/9/2006
 3  RLS Muscle aches and soreness in legs and upper arms similar to flu like symptoms. Daytime drowsiness. Nasal congestion. Ocassional weird dreams, I started taking .25 mg of Mirapex which worked fine for a month and started to notice the day after taking Mirapex I experienced muscle pains similar to having the flu. I cut back the dosage to .125 mg and it is effective in controlling the restless legs but I still feel the muscle aches and pains. My neurologist says Mirapex should not cause muscle pains. I was taking Requip before switching to Mirapex. Requip was effective for about six months and then I started getting severe augmentation so the doctor started the Mirapex. I sleep through the night but feelsleepy, achy and sore most of the next day. I take Mirapex about every other night and the day after I do not take it I do not experience the muscle aches and pains. M 53 4 months
10/8/2006
 4  RLS works well for my RLS---I'm now sleeping most of the night for the first time in my life! One major side effect though, I am developing joint pain in my ankles, arms and especially my wrists and fingers---seems similar to arthritis pain. The pain seems to be getting progressively worse. Since I am a songwriter and guitar player by trade this side effect is very worrisome. Anyone having the same problems with this side effect? And if so does it get better with time or worse? M 57 6 months
10/5/2006
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