FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  infertility severe head aches, sudden tiredness, severe mood swings, anxiety, very server depression, suisidle thoughts even, neck ache, feeling like I'm gaining weight, fluid retention, very sore breasts, heavier than normal periods, teeth grinding and clenched. I am a fitness instructor but since taking this medication I've lost my drive to workout completely. I wake with head aches every day even when in not on the meds (I take it for 5 days a month) my moods are horrible I have gotten more and more depressed and feeling quite sad. I'm giving it this last go this month and seeing a new fertility dr next month to review. hate this medication. only good thing is it has helped with my ovulation. F 38 3 months
low
10/31/2014
 3  Breast Cancer Stage 1 Arthritis, weight gain 30 pounds, sleeplessness, brain fog (at times), stiffness in joints, back hurts.....all joints really. I just came off Femara 4 days ago. Can't to see what goes back to normal and of course the weight loss. Now that I am off Femara I having having hot flashes off and on all day and night. Googled this and found "many" who are having the same experience. Hopefully this will fade away with time. F 62 5 years
2.5 1X day
10/11/2014
Email
 1  stage 2 breast cancer 1 days
9/22/2014
 2  breastfeeding cancer Hot flashes, feet and hand pain. Joint and muscle pain F 57 1 days
30mg
9/20/2014
 3  Estrogen Blocker for Breast Cancer I have joint and bone pain in the mornings when I get up but it subsides as I start walking around and doing things. I have had a lot of itching and itchy bumps on my elbows, rash or hives on my back, But it could be because I was mixing organic coconut oil in with a new lotion I got at Whole Foods. I have since stopped using them both and I will see if the itching goes away. I have intense vaginal itching at night and it wakes me up, probably from the dryness associated with taking the Letrozole. I used all kinds of non-itch creams for that area, but it is still there. I am taking the generic Femara from CVS. I am wondering if there might be a difference in the Letrozole from Walgreens as someone mentioned one time. I do on occasion get very angry with my spouse for the least little things, and thankfully he is very patient with me. Other than that, I guess I am doing great. {Thank you Lord} Could people start adding which pharmacy they are using? I am wondering if some of the Letrozole is different at each pharmacy??? F 61 2 months
2.5 mg 1X day
9/15/2014
Email
 1  breast cancer Immediately, I had mood swings and body aches. Later, there was fatigue and depression. My onc took me off for a month and eased in the doses over another month. Meanwhile, my internist put me on cymbalta, which also helped the body aches. Over the past couple years my concentration has decreased and now, four years after starting, I'm having dental problems. I'm pretty sure it's Femara's effect on my bones that is causing the problems although the docs won't admit it. F 60 4 years
9/14/2014
Email
 2  Stage 1 er+pr+,her2 neu NEVER had issues w/ joints until taking this med. Daily pain predominantly in knees, shoulders, feet, and hands. Pain is significant enough to warrant taking tramadol and flexeril at night. Fatigue. Sitting for any length of time worsens the symptoms in the knees and hips. Mental fogginess and forgetfulness. Vaginal dryness and pain with intercourse. Had stopped regular exercise (used to run) because of the pronounced pain in the muscles and bones I would experience the next day. Have been doing research and am seriously contemplating stopping this medication due to the known side effects of osteoporosis and heart disease. Did Adjuvant Online with my doctor prior to decision to start femara and my risk is very low - it is difficult to make a decision when everyone acts like you will die if you stop. F 47 6 months
2.5mg 1X day
9/10/2014
Email
 4  breast cancer stage II stiff hands upon waking, mild "warm flushes" So many of you have experienced unfortunate, dramatic side effects. I just want to be on record for those thinking about starting any of these meds that may become worried after reading such upsetting stories. Many of us do well, with minimal adverse reactions. For those that suffer, please work with your prescriber to find a solution. Try a drug holiday, change to a different AI, begin an antidepressant and BE SURE TO EXERCISE DAILY! F 56 6 months
2.5mg 1X day
9/7/2014
Email
 3  breast cancer Joint and breast pain stiffness F 64 5 years
2.5
8/11/2014
 1  Breast cancer Right away I had terrible back pain.I dismissed the pain thinking it was a pulled muscle.Pain also in joints and breast pain. The worse side effect is a severe rash ,on my neck,face wrists and the breast that was operated on. On steroids now to try and get rid of the rash . Will not take anymore drugs. F 58 2 weeks
2.5mg
8/9/2014
Email
 2  Breast cancer grade 2 mastectomy Vaginal atrophy,joint stiffness, extreme fatigue and tiredness , hot flushes, insomnia Vaginal atrophy almost immediately. Over the last 12 months insomnia ,lethargy,and extreme tiredness. I have lost me! Will continue with the drug at present but it seems to me that the cure is worse than the disease. Feeling quite depressed. Rads no Chemo. F 64 12 months
2.50 1X day
8/6/2014
 2  Hormone positive breast cancer joint, muscle and bone pain, high cholesterol, thinning hair, diarrhea, extreme vaginal atrophy, loss of sex drive, arthythmia, blood clotting issues, extreme stiffness, tiredness, horrible back pain and virtually non-stop hot flashes and night sweats every night, insomnia, anxiety, itching, and breathlessness!!! For me, this drug is a quality of life REDUCER. I do not believe we have sufficient information about FEMARA or other aromatase inhibitors. And I have read many times that FEMARA and other AIs don't enhance life expectancy, mainly due to their contribution to heart problems. So, if the cancer doesn't get you, your heart will ... !!! F 51 3 years
2.5 1X day
8/6/2014
 5  post Ca breast Swollen, painful and stiff fingers and feet, which are worse in the mornings. Dreadful mood swings......I can be so nasty at times to my partner. Palpitations. Cry easily. Poor concentration. Poor memory. Loss of libido. F 54 2 years
30 1X day
7/28/2014
Email
 5  Breast Cancer 2B Insomnia. Mild hot flashes. No sex drive. F 54 1 years
7/25/2014
 1  Breast cancer Really bad hot flashes Headache Painful joints Insomnia F 66 2 weeks
Once a day
7/5/2014
 1  stage l estrogen positive Insominia, hot flashes, chills, nausea, increased blood sugar, increased blood pressure, tired, racing heart and constant pain. Decided to ask doctor to stop taking letrozole. Fingers in both thumbs were in pain. Got a cortizone shot for the left trigger finger but it helped only for one week. Still in pain. F 70 10 days
2.5 1X day
6/26/2014
 1  breast cancer, earl stage gradual worsening of hand stiffness, ankle stiffness, tendonitis thumb, fingers stiff, quality of life going down hill wondering if this medication is making my tendons and joints age fast, am off it for 1 month, considering switching to tamoxifen F 62 2 years
2.5 mg 1X day
6/14/2014
 5  Breast cancer Initially no side effects. after six years I blamed my weight gain on this med. I had become lethargic and down-hearted.Cancer responded well to this and other chemotherapy: cancer numbers receding. Taken off Femara three months ago. Energy level and general disposition are improving. F 68 7 years
30 1X day
6/10/2014
Email
 2  Stage 1 invasive lobular breast ca I started Arimadex 8/2012. Could hardly walk by 12/13. Horrible joint pain and sweating/hot flashes. Wanted to try femara, wanted one of the above to go away. Right away my joint pain was better, and still is better than with arimadex. Still sweating a lot, but not quite as much as with arimadex. But these muscle spasms in my ribs and back are terrible. It spreads across my chest and hurts like crazy. It is beginning to affect my work. My hands are getting stiffer as time goes on. I'm not sure what to do, go back on the other?? Or go back and forth?? Vaginal atrophy is really a problem too. F 59 4 months
2.5 mg 1X day
5/6/2014
Email
 3  to reduce estrogen production Hot flashes, thinning hair, muscle pain, joint stiffness, fatigue, inability to lose weight (although I work out 6 days a week and have reduced my caloric intake), mood changes (depression), difficulty in sleeping through the night. I would really like to stop taking this drug but cannot risk the return of breast cancer. I am trying to convince myself that my mood changes are not due to this drug but am convinced that Femara is the culprit. I was so positive and upbeat before but now I seem to alternate between a constant desire to cry, hide in my house or hit something. BUT I have committed to not giving up or giving in to depresssion - thank God for prayer! The physical exercise does help - especially my 4 mile walks but I'd sure like to see some results from all the working out. I'll be discussing my mood with my Oncologist at next visit though - I can't survive with my mood in the dumps all the time - life is too precious and I want to savor each moment. F 53 9 months
2.5 1X day
4/12/2014
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