FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Breast cancer Though having joint pain this drug at least helps me to survive F 50 3 years
2.5mg
10/21/2012
 1  Breast cancer Terrible hot flushes, joint pain, sleeplessness, crying, ageing, tiredness. Lost use of ring finger on right hand and rest of fingers and thumbs affected and very painful. Mornings are the worst. Was meant to be on it for five years only lasted five months. F 64 5 months
2.5 1X day
10/13/2012
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 4  stage 2 breast cancer Had started with femara four years ago. Switched to generic letrozole. Wake up stiff in morning. By time I get downstairs stiffness gone. Stiff when I get up from chair. Excessive weight gain but my tumid markers have gone down. Hopefully this medication will prevent reoccurence. F 59
2.5mg 1X day
10/8/2012
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 3  Endomtrial Stromal Sarcoma Stage 2b Stiffness, joint and bone pain. Burning sensation in hands and feet. High cholesterol, high blood calcium level. Hot/cold flashes and night sweats. Dry skin, change in hair texture. Dizziness. Loss of appetite. Fatigue. The first three months on Femara the only side effects were hot/cold flashes, night sweats, loss of appetite and dizziness. At the three month mark the joint and bone pain started and has some days been very painful. I also found out I now have high cholesterol and high calcium. I read an article the other day that says if a patient takes Femara and experiences new hot flashes and night sweats along with joint pain within the first three months of taking Femara that their cancer is less likely to recur. I sure hope that's correct and the benefits out way the risks. Will reevaluate at the 6 month mark if I want to stay on this drug. F 50 4 months
2.5 mg 1X day
10/7/2012
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 2  Fertility Issues Ever since I started Femara I haven't been feeling well. I've had really bad abdominal and vaginal pain. I've also had hair loss, upset stomach, acne, and hot flashes. I don't think I will take this medication again. It's made me feel horrible. F 23 5 days
1X day
9/22/2012
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 3  Breast Cancer Stage1 been taking this pill for 4 years and 9 months - suppose to take for another 3 months - but i cannot do it - i am so beat up with this pill - i just can't take another day with it - hope everyone has better luck with the side effects than i have had with it. have had pain in joints - horrible pain in stomach - and list goes on. F 68 4 years
2.5 1X day
9/15/2012
 1  Breast cancer Depression lump in throat joy flashes night sweats joint pain tired F 59 4 months
2,5
9/11/2012
 4  Stage III BC with 5/7 lymph nodes+ I have many of the same side effects that everyone else has, but mainly the joint pain, hot flashes, insomnia and weight gain. I want to add that in addition to the turmeric/curcumin supplement, cinammon is also a natural anti-inflammatory. I actually take a teaspoon of cinammon mixed with a small amount of water and agave nectar every morning, and have much less joint pain with this supplementation. I also take a turmeric supplement but I was not aware that black pepper was necessary to fully complete the benefit of the turmeric. I will also add that, even though it is very hard to do, exercise actually help control the joint pain. It doesn't feel like it when you hurt while exercising, but having had to give it up for several weeks, the pain was much greater. I would very much appreciate the person who posted before me to give me the link to the turmeric supplement that you are taking, please. F 57 2.5 years
2.5 1X day
8/27/2012
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 2  Breast& lymph node cancer,brac gene Side effects- increasing over time...hand, feet, knee, & jaw pain...exhausted but can't sleep...can't focus or remember things...nauseous & dizzy...and I'm overly emotional. The hot flashes have decreased over time. Fast weight gain over a short period was actually the final red flag that my side effects weren't menopause or stress. (i gained 25-30 pounds in 3-4 months) I figured out all my symptoms were due to the letrizole...especially after I found this website & saw how many women are going through the same exact thing. I MAY HAVE FOUND A SOLUTION TO MY SYMPTOMS THAT COULD HELP YOU TOO!!!!! My boyfriend is a doctor & he did a ton of research to come up with two things to help me naturally (I refuse to take another drug to fix the original drug). Vitamin b has helped with my energy & a Tumeric supplement with black pepper (for easier absorption) has done wonders for me with literally everything else. Look up the benefits online & you will be floored that you didn't know about it sooner. Pharmaceutical companies are coming up with a synthetic form of tumeric for cancer patients very soon...they don't want you to know what a miracle herb it is in its natural form. I feel like I'm getting my life back ...and I've only been on it one week and seeing improvement with ALL of my problems. I am floored that no one told me about this. Please do yourself a favor & look into it...via Internet...your doctor...other patients. I hate to see anyone suffer another day when relief can be so simple. Lastly...revisit the do & don't eat list for cancer foods...they make a big difference too. May god bless each of you...I admire all you have overcome...you are strong women!!! F 44 2 years
2.5 1X day
8/26/2012
 2  post breast cancer & elective BSO Aching muscles & joints all over body. Particularly severe plantar fascitis. I am 49 and feel like 99. Finding it very painful to walk, get up off a seat, climb stairs, get out of the car. Take the aches & pains of the worst flu you can imagine and quadruple it! Also too much weight gain & no energy. Can anyone comment as to whether the side effects disappear when you cease taking Femara? Currently trying to weigh up if this current poor quality of life is worth it and whether to continue this treatment. F 49 2 months
2.5 mg 1X day
8/18/2012
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 1  BC Stage 1 This is follow-Up to 1-24-2012 post. Although better, still having back pain/knee pain every day. I know this was Femara that caused.Never a problem prior to taking Femara. Only took for 90 days before ditching this poison, but now 8 months later and still having pain problems. Stay away from this! So far my BC check-ups are good. But will I ever recover from this horrible drug??? F 64 90 days
1X day
8/16/2012
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 1  Breast a cancer caused by HRT Hot flashes, insomnia, weight gain, arthritis in my hands & feet but worst of all vaginal bleeding. I just had a D&C &will have the results this week. If It comes back benign I'm going to be very upset. All this as a result of HRT& Femara. We're stupid to trust the drug companies, they want to keep us sick. We should turn to alternative medicine. F 66 4 years
2.5 1X day
8/12/2012
 4  breast cancer stage 1 hot flashes, pain in joints especially thumbs, memory loss pain in feet , shoulders I have had one vacation from Femara for two weeks and i felt like a new person. My quality of life is miserable but i keep telling myself it could have been worse. The over all pain in joints and muscles can bring me to tears. I have to use a cane quite often but will do my best to get through the next four years. Had carpel tunnel surgery on both wrists three months ago which came out of the blue and i attribute to Femara. F 71 14 months
2.5 1X day
8/2/2012
 4  adenosarcoma in endometreosis Severe joint, bone pain, headaches, nausea, nightsweats, blurred vision, insomnia, chills to roasting in matter of minutes, tiredness, etc I have a rare form of cancer as my endometriosis is outside of the uterus. Had hysterectomy/ooperectomy 20 yrs prior to cancer diagnosis. I have had numerous surgeries for endometreosis I have gone as long as 8.5 yrs in between. Thus far I've gotten by for 7.5yrs. I'm on this med for life but am at the point of deciding if quality of life that I'm currently experiencing is worth taking it. M 56 7.5 years
2.5mg 1X day
7/13/2012
 4  Breast Cancer Stage 1 bad stomach pains after eating - includes pain in back - ribs - collar bone - jaw - pain in legs and ankles at night when laying down - very hard to get out of a chair - move real slow - best of luck to everyone - Blessings F 68 4 years
2.5 1X day
6/29/2012
 1  Breast cancer stage 3 Where do I begin. This drug has changed my life and not in a good way. I used to be very active but now I have to force myself to walk around the block. Pain is everywhere with sharp stabbing pains in my feet and hands. I usually get that in the evening when I am sitting or laying on the couch. I have had carpal tunnel surgery on my right hand (and I am left handed. What does that tell you.) and the left hand is being done aug.2nd. I too am considering quality of life vs this horrible drug. F 62 14 months
1X day
6/29/2012
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 3  Metastatic Breast Cancer (Bone) The first week I began taking this drug I experienced hot flashes, depression, loss of appetite and unbelievable aching plus stiffness in my joints and muscles. My hips being the worse. This drug was worse than the 12 weeks of chemo. But I found help. I came upon this forum and read a couple of suggestions of taking collagen, specifically NeoCell Collagen+C from Costco and Glucosamine. I had relief within 24 hours. My nutritional oncologist suggested HMC Hesperidin for the hot flashes. Rhodiola Rosea for mental clarity and depression. I feel so much better. Yes I still have hot flashes but nearly as many. She also suggested Phenylalanine-D for the pain. All of this has helped. Also, keep moving. Yes it's difficult especially in the morning or after sitting for a while, but my dr. agreed it's important to force yourself. I had good response to the chemo and my oncologist feels this drug can keep the cancer at bay. I gave this a 3 rating based on the short time I have taken this. F 57 45 days
2.5 1X day
6/19/2012
 5  Ductal carcinoma some joint pain... taking letrozole - generic joint pain.. other aging issues... and maybe some chemo damage. but very well tolerated... Primary Physician prescribed Arthrotec for joint pain... worked majic... moderate discomfort not worth the risk of not taking... F 62 3 years
2.5 mg 1X day
6/7/2012
Email
 1  post breast cancer chemo/radiation My comment regarding this drug is posted in April of 2010. At that time I was going to tell my Oncologist that I was going to discontinue taking Femara as "quality of life" was as important, if not more so, than living with extreme pain this drug was giving me that virtually gave me no productive life. Since that time, after discontinuing Femara, my joint pain has gradually disappeared, though I still have hip pain that radiates into my legs which is a combination of degenerative changes and I firmly believe, as a result of this medication. Prior to taking Femara and even after chemo and radiation, I did not experience pain until Femara came into my life. So far, by the Grace of God, I am still "cancer free" and feeling like I have a life once more. I still read comments about this drug and my heart goes out to those of you who are experiencing the debilitating effects of this drug. F 64 3 months
20 mg. 1X day
6/5/2012
 1  Breast cancer severe aches and pains and chronic sleeplessness F 63 5 days
30mg 1X day
6/3/2012
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