FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  breast cancer Almost immediately I had joint aches, especially in hands and feet. I quickly developed hammer toes, baby toe and 4th toe, particularly. Bone density loss in hips was 9 percent in one year. Femara is prescribed for five years following tamoxifin. Hopefully, the insult to bone and tendon will be mitigated by a cancer-free future. So far, no problems w/ BCA, and I'm almost 10 years out. F 63 4 years
3/1/2009
 3  Infertility initially through day 5-9 mild headaches (don't usually get) after day 9 bloating, joint pain in knee and elbow don't feel like working out which I usually do daily at 0520 for 30 min two weeks later- back pains (don't usually get)and fatigue follicles responding really well to 5 mg femera F 37 3 months
2/21/2009
 3  1st stage breast cancer Bad hip pain & stiffness - hard to get up from a chair - going up stairs is a nightmare. I get really sleepy once I sit down to relax after work. I started taking Femara in May 2008 after chemo, radiation, & Herceptin. The hip pain was not too bad at first, but has gotten worse the last few months. There is also a feeling of achiness like the flu. I have tried Tylenol and Motrin, but do not see any difference. I have been taking the Femara in the morning, but I think I am going to try taking it before bed to see if that helps. The hip pain & stiffness is mostly when I try to get out of a sitting position or do the stairs. I push myself to keep going - I work fulltime and have a husband, 2 children, & 4 grandchildren - so I keep busy. Seems I am tired early in the evening, but sometimes when bedtime comes, I am wide awake - go figure. I felt great while having chemo & radiation - not many bad effects. I have spoke to a couple of ladies that are on Femara and they all say the same thing about the joint pain, achiness, & tiredness. They need to make a medicine to counteract the side-effects. I hope th 55 9 months
2/17/2009
 1  prevent breast cancer bad joint pain, hair loss, nausea,fatigue F 58 7 months
2/15/2009
 1  Stage II Invasive BC daily shoulder, upper and lower arm, elbow, wrist, finger, hip, knee, and general roaming joint muscle pain; insomnia; possibly depression (aggravation of). On a scale of 1-10, I would say that in general, the level of pain was between 4.5 to 6. I have been taking for 22 months. The pain that I experienced was horrible. There were times when I had pain in every joint in my body. I am a yoga practitioner and teacher in training and became so discouraged with the pain that I quit taking it on Weds, Feb 12. This experience was like a slow painful death. Within 5 days of my discontinuing it, the pain is almost gone. I find myself bracing to sit down, pick up my grandchildren, and stand up after sitting for any length of time. Today, I was able to sit down in church after standing for about 4 minutes, without pain. Praise God. My doc recommended 5 years of taking this med. I could not imagine living with the pain one more day, let alone another 3 years. Life is too short. F 54 22 months
2/15/2009
 3  Breast Cancer 3 Stiff and swollen fingers and knees, legs are swollen every night, low labido, slow motion, memory, weight gain! Is there anything to help the stiffness and swollen joints, I do Curves, walking and try to watch what I eat. I am on my feet all day long for work. Had Radical massectomy, chemo, and radiation. F 49 9 months
2/8/2009
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 4  bc 11-yr remission Weight gain has been difficult to cope with, trouble walking but may be due to adhesions from reconstruction. Going off Fermara now as I've reached the protocol limits. Ongoing study not finished so keep praying and enjoy every day. Know anyone that went off of it? F 65 2.5 years
2/6/2009
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 1   painful muscles and joints, day and night sweats, no concentration, memory loss, can't stand or walk for very long, hands and wrists very painful I went off this drug a week ago cold turkey, have not told my dr. yet. My husband agreed with me that quality of life is important. Had lumpectomy in 1992 and masectomy in 2007 with chemo - same side. Took chemo and radiation first time. F 65 14 months
1/31/2009
 2  As a follow after breast cancer severe pain in the lower calf of the foot F 75
1/28/2009
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 5  ESS I had to go off because of the joint pain and tendonitis. I am wondering how long the pain stays with you after you stop taking it? I was told 3 to 6 months. Anybody? Like to hear comments on how long it took to get back to normal and for pain to recede. I am off it close to 3 months and still have pain. Nothing seems to help it, only time. It worked perfectly well and did what it was supposed to do, suppress the estrogen in my body and keep me stable which it has done for over 5 years. Anyone taking it more than 5 years with mets that are stable? F 70 6 years
1/26/2009
 2  Stage 1 Breast Cancer Each and every morning I wake up with joint pain. I find it hard to walk and my fingers ache. I can usually walk the pain off within a few minutes. Also later in the day if I sit at my desk at work for too long I get the same discomfort, again able t walk it off. I also have gain some weight and I hope that does not continue. After reading other posts, now I think there are more other issues I have not addressed. I had stage 1 breast cancer and it was hormone receptor positive. I was diagnosed in April of 2007 and initially took Tamoxifen until my hysterectomy in August of 2007. After that I switched from Tamoxifen to Arimidex. I had joint pain and weakness in my arms and switched to Femara in April 2008. I was hoping that switching to Femara would ease my pains and it did not help. In discussions with my doctor I guess I have another 3 1/2 years to put up with the side effects. F 49 8 months
1/25/2009
 3  Breast cancer Hip and leg pain especially at night. Difficulty moving from sitting to standing, foot pain when standing a long time and thigh pain when walking. I have found that ultrasound done by a PT helped ease the hip pain as does sleeping with a pillow between my knees when sleeping on my side and under my knees when sleeping on my back. F 70 30 months
1/23/2009
 5  Infertility No side effects except pregnancy:) Clomid and Glucophage didn't work after 4 cycles so my OB switched me to Femara and I became pregnant after the 2nd month. Now I am 16 weeks along and everything is great so far. I was taking 5mg on days 3-7 of my cycle. I ended up ovulating on day 21 of my cycle and could tell thanks to the home ovulation kits. I also took Mucinex during my ovulation time to make my all of my fluids thinner so it is easier for sperm to travel. F 27 10 days
1/21/2009
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 1  Breast Cancer Stage 1 Severe joint, muscle and bone pain. Tired. Feel like a 80 year old when I am 48. Hard to get up and move in the morning. My doctor took me off and told me that the side effects would go away. He wanted me to start Aromedix after a 30 day hiatus. The severe pain has not gone away. Has anyone experienced continuing pain after going off Femara. Has anyone had issues with Aromedix. I am at the point of not taking anything if it impacts my quality of life. F 48 7 months
1/21/2009
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 1  br ca joint pain, stiffness, swelling trigger finger "pseudo" gout knees F 60 1 years
1/17/2009
 3  to prevent recurrence of cancer Low libido, vaginal dryness, mild hot flashes. I'm also having some other mild problems such as a sore jaw and knee pain, but I had pre-existing arthritis, so I don't know whether any of these problems were caused by Femara. I won't know whether Femara is preventing a recurrence of cancer until it hasn't recurred for many years. F 67 4 months
1/10/2009
 3  Stage 2 breast cancer WEIGHT GAIN - WEIGHT GAIN - WEIGHT GAIN. I CAN PUT UP WITH THE OTHER SIDE EFFECTS SUCH AS JOINT PAIN AND DEPRESSION, BUT I AM FINDING IT HARD TO COPE WITH THE WEIGHT GAIN. F 55 13 months
1/9/2009
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 3  Breast Cancer Stage 2 Continued from entry on 1/06/2009 Went off femara for about 6 months after being on for 3 1/2 years. I was really afraid I was going to feel that way forever. I just wanted everyone to know the pain does eventually subside which was becoming a big concern of mine. I decided to finish my 5 years on femara as I am now reassured the pain is just "temporary". I can suck it up for another year and a half. I've been back on for 4 days and I can already feel it all coming back. Don't know if I'll make it but I am going to try. F 50 3.5 years
1/9/2009
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 4  Breast Cancer I have been on Femera for about a year. I did not realize it was Femara that had caused me severe drowsiness. I had a hard time stay up at work every afternoon and struggled to get up every morning. I experienced bad pains in the hips, foot and other joints of the body. I started taking 1200 mg Caltrates and 1000 IU Vitamin E daily. This has helped me with joint pains. I also started taking Femara with a full stomach at night daily. I discovered that helped reduced my drowsiness for the following day. I also excercise 3 times per week and found YOGA to be most helpful to reduce joint pain. I am on a diet with most vegetables, beans, fruits, nuts and less than 20% of meat daily. With all efforts above, I have been able to maintain my weight with minimum joint pain and reduced drowsiness. I have no depression and no insomnia. I still wish I do not have to take Femara and imagin what my life would be like without it. I guess I have a few years to wait. Till then, I will continue my fight against breastcancer. F 45 10 months
1/8/2009
 4  Breast Cancer Joint pain, especially in my back and legs. Weight gain. Feel like an 80 yr old woman most days. Had depression as a result of chemo putting me through menopause, but am taking Paxil to deal with that...and is working very well. 5 years cancer free!!! Had two lumpectomies, chemo and radiation in 2003. Menopaused from chemo. Took Tamoxifen for 3 yrs and have been on Femara the last 2 years. Thought I would be done with Femara, but oncologist advises me that I should take it for another 5 years. Tamoxifen was a piece of cake compared to Femara. I really hate the side effects of Femara, but believe the drug is working the way it should as I've had no recurrence. F 47 2 years
1/7/2009
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