FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55


RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Stage 4 Breast Cancer Almost everything described by others. Wanted to commit suicide. Most side effects have gone away entirely since I started to eat Oatmeal and Buckwheat 30 min. prior to taking Femara. I am also taking B12 vitamins. F 70 6 months
6/12/2008
 2  breast ca-stgI,ER-/PR+/HER2-/BRCA1+ Joint pain especially in thumbs and wrists (hard to carry things), achy all over, stiff when I get up, general fatigue I am considering going off due to quality of life. I've had a bi-lateral mastectomy, oophorectomy, no chemo, and scared to not take something for prevention. Interested in any others experiences. F 50 6 months
6/7/2008
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 4  Infertility Irrational Anger, but only while taking it and not after like other medications I am taking 5mg cd3-7 to encourage ovulation and follicle stimulation. I couldn't take Clomid due to emotional rollercoaster for a whole month after taking it. At least with this it is only for the 5 days I am taking it since it is out of your system in 5 days. We have yet to see how my ovaries react in full. Last month was a sit out month and I had an ultra sound at cd6, but too early to tell how many or the follies we saw would mature. We are very hopeful! F 32 5 days
5/6/2008
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 3  Infertility Major debilitating headaches that would bring me to tears! I cried uncontrollably. This happened as the meds were wearing off. Had a sonogram today to see how my ovaries were responding. So far so good. We'll see how it goes I guess. I've heard from someone else who used Femara and they got PG the first month of treatment. F 37 5 days
5/5/2008
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 4  Breast Cancer in 1999 PROGRESSION HISTORY -- sprinkle with chronic type fatigue for the whole misery picture: Bottom of feet extreme pain to walk; Nasty scalp eruption; Weird urinary infection; Mean ankle muscle problem; Overall body crippling stiffness w/’flu-like’ pain; reaction to NSAIDs--swelling ankles; The “Brickwall impact” that’s taken all balance out of my life; Daughter told me to check Internet and I found this site. Has anyone else’s muscles/joints/nerves ‘pure pain’ NOT stopped after coming off FEMARA? Mine didn’t. Since I’m stuck with pain that’s not going away and can’t get any worse, I requested the Oncologist last week to ok resuming an anti-cancer drug for that protection against cancer. Request refused. Last night I ordered an herb blend to replace that drug – I’m desperate -- told Rheumatologist first and he said it wouldn’t affect current meds. F 75 21 months
5/2/2008
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 3  b/c Weight gain, join paint, terrible weakness in my back to the point if I go to a store, have to use a cart even if I don't need one just to hold onto to help me walk. Has gotten worse as time has gone on. I work full time and have managed, but it's getting harder. Better in a.m. By 4 p.m. barely can make it to the mailbox 50 ft away. Has impacted in a very negative way on my quality of life. Have a call into my onc. Supposed to go off Femara in Oct after 3 yrs but may ask if I can quit sooner. When you can't walk with your grandchildren or husband, what kind of life is that? F 65 3 years
5/1/2008
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 5  Infertility/Ovulation Induction pregnancy After one successful pg w/Clomid & Metformin, the combo was not working this time and was causing side effects after 4 months, so I was switched to Femara. It worked the first month. No side effects. Healthy full-term pregnancy. F 34 5 days
4/29/2008
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 2  Stage III Metastic IBC severe stiffness and joint pain in ankles/feet. Weight gain. Hot flashes. 50,000 icu Vitamin D, hot spa tub for fee/ankles, requip for RLS, Effexor for hot flashes, STAY ACTIVE! 48 6 months
4/28/2008
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 3  AVOID BC RECURRENCE Nothing for almost three months then stiff joints(especially fingers and neck), muscle pain and weakness (especially arms), bottoms of feet ache, extreme vaginal dryness. Very stiff all over in the morning and great difficulty getting up from a chair. Aches when I toss and turn at night. But no depression and move well so long as I am up and walking (unless pain in the soles of my feet kicks in) so I keep thinking I can tolerate it and another drug might be worse. My greatest fear is that the side effects are permanent and won't go away when I stop the drug. I take a multivitamin, vitamin D, red yeast rice (managing cholesterol level), glucosamine (easing joint stiffness), three ibuprofen three times a day for aches and pains, a stool softener and, most nights, Ambien. When I travel I need a separate bag for the medications and supplements. Considering getting a softer mattress. F 63 8 months
4/27/2008
 3  breast cancer calf, ankle, foot, and toes cramped - both sides - very severe - couldnt raise my feet from the floor to walk. this just happened and i'm not sure what to do. i go to the onc. in about a month so i will ask then. this scared me. How do we know if it is working to keep the cancer away? F 54 1 years
4/24/2008
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 4  Stage 2 Breast Cancer Hair thinning, bone and muscle pain, weight gain Gained 15 pounds - can't lose it. Never been an exerciser but started aqua-therapy which has all but eliminated muscle and joint pain. The key is range of motion and water therapy does the trick. The temptation is to slow down because of pain but exercise has made a difference for me. I take 2 advil at bedtime. I'm staying on femara until my oncologist says to stop. F 62 2 days
4/23/2008
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 1  breast cancer Severe joint pain, to the point of being an invalid. Took it for 21 days. My oncologist thought it was in my head so I changed oncologists and the new doctor, my hero, put me on Evista instead. It's the latest drug for bc prevention. The only side effect I've had is occasional hot flashes. Thank you, Dr. Robertson, for listening and helping me!! F 63 21 days
4/22/2008
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 2  prevent reccurence of breast cancer leg pain, joint pain, muscle weakness, extreme fatigue, moodiness, increasing dizziness, muddled head I have a med check Friday....I do not want to feel like this every day of my life....the difference in getting cancer again or not for me is femara decreases my chances by 8%...is that enough to go off it? I HATE how it makes me feel...I am only 50, but feel like 80....can hardly stand up at night or walk. I did tamoxifen for 5 years with little to no side effects. F 50 3 months
4/20/2008
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 1  Breast Cancer Most side effects have subsided or gone away entirely since I stopped taking femara six weeks ago. My oncologist suggested taking anti depressants to combat the side effects I was experiencing with Femara. I asked why would I want to get addicted to a drug....I am not depressed. My body has rid itself of most of the side effects except for foggy brain, and arthritic fingers. AM debating...to go back on Femara for two more years or not.....feel so much more human when not taking it. F 45 2 years
4/18/2008
 2  breast cancer Joint pain-ankles, knees, elbows, hands.Shortness of breath coming up stairs or running. Raised cholesterol. Hair falling out. Rapidly ageing skin. Loss of libido.All this in one year and I have an extremely healthy diet-lots of fruit and vegetables, whole grains, little meat etc, the perfect weight for my height and have always exercised daily.I feel as if I have aged ten years. Yesterday I decided to stop taking Femara as I feel that I have a greater risk of having heart disease or a stroke and of being disabled by arthritis if I continue, than of getting cancer.(No lymph nodes were affected and I had a mastectomy) I wish I had found this site sooner, it would have persuaded me stop taking it sooner. F 57 13 months
4/15/2008
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 3  recurrant breast cancer Joint aches, hip pain, neuropathy, weight gain,heart palpitations, and did I say joint pain, I mean extreme joint pain. I was on Tamoxifen for 5 yrs, went off and 2 mo. later had a chest wall recurrance, this time had chemo and radiation, and am now on Femara. Was told I would have to be on it for life. Which I hope is a long time. But could just cry sometimes with the pain and discomfort. Would appreciate any suggestions for the pain and wt gain. 57 1 days
4/11/2008
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 3  breast cancer/double mastectomy arthritic pain in shoulders, neck, back hands, wrists and feet. extreme vaginal dryness, loss of libido. fatigue. insomnia. so many have mentioned foot pain. the only shoes i can wear are called 'crocs'. if i try to go barefoot, i cannot walk more that four steps without flinching. these shoes are a godsend. however, they don't look good with dresses!!! but, at this point, who cares? i take one vicodin in the morning as well as meloxicam, an anti-inflammatory med.; folic acid with b vitamins rid the migraines. i take one tylenol-3 at night for foot pain, as well as one extra strength tylenol, plus 100mg trazadone and 1/2 benedryl to help me sleep. on 12/28/10 i plan to take my last femara. i fervently hope that these side effects will go away on that day. if not, will the doctors tell me that it's all a result of post menopause? will this continue till i die? i don't know if this medicine is working or not. perhaps the fact that i haven't had a recurrance means it is working. F 60 2 years
4/10/2008
 1  breast cancer pain in about all joints, hot flashes, constipation, cannot sleep. weight gain. Hungry all the time. Dizziness and moody. I was a stage one grade three with an onco test score of 18. I opted out of chemo and did the 33 radiations. Went on arimidex first of Dec. was switched to femara 2 weeks ago. Does anyone know how much protection a person gets from these drugs. I have gained 25 pounds feel like I am 90 and cannot even walk a block without severe pain. Have thought about quitting. I can handle all of this but the pain and when you cannot function because of the pain it is scary. F 59 14 days
4/7/2008
 2  IIA, N-neg ER/PR+/HER-2+ breast ca Joint pain - shoulders, arms, wrists,fingers,knees and hips. Muscle weakness. Occasional hot flashes. Low libido. Arimidex was prescribed after chemotherapy and Herceptin treatment. The side effects of Arimidex became intolerable (muscle weakness and pain, joint pain, hot flashes, low libido, low energy). I told the doctor I would not take Arimidex because my quality of life was so threatened. She discontinued Arimidex for 10 days. Within 3 days, all pain went away and I started feeling human again. Then started Femara. I have been on Femara since October 2007. At first everything was fine, but then I started experiencing similar side effects. On Arimidex, muscle weakness and pain was in my legs and pelvis. On Femara, most of weakness and pain is in my upper body - shoulders excruciating, carpel-tunnel like pain in arms, thumbs, fingers. This pain is especially severe at night. I am beginning to have leg and knee pain, as well. I will be seeing oncologist in April and will discuss discontinuing Femara. I am almost 2 years since diagnosis, s/p bilateral mastectomy, Adriamycin, Cytoxin an F 56 6 months
3/30/2008
 2  prevent reoccurance of bc pain in my hips, shoulders, now traveling down my arms. numbness in my right hand (I thought maybe it was carpel tunnel) tiredness. I have had an increase in cholosterol and blood pressure. I'm now thinking maybe it's all the femara, not just that I'm getting old! Took Tamoxifin for 5 years after bc surgery/chemo.(12 years ago) then went on Evista (raloxifene) for about 5 years (no problems) then swithced to femara last May. Thought my hip pain was coming from walking so much (trained for BC 3 day walk).So glad to have found this site. Will call my oncologist and see what can be done about coming off and possibly awitching back to Evista. F 54 9 months
3/27/2008
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