FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Prevent BC recurrence Hair losss, weight gain (due to a good appetite and eating more), minor lower back pains, which would go away once I moved around. I took it for five years and in general have not had too many problems with it. My oncologist just took me off the drug as he doesn't feel continuing it would add more value. F 57 5 years
7/25/2006
 2  Breast Cancer I have taken femara for the past 4 1/2 years. Within one month of starting , I developed severe hand and foot pain - getting to the bathroom in the morning was terrible. The pain has gradually improved in my extremities, but knee pain is bad when going up and down stairs. I feel like an old lady. No libido at all. Weight gain of 20 lbs. Can't wait till I reach the 5 year mark - when I will stop.There has to be a better way to combat recurrences. F 50 4 days
7/25/2006
 3  Breast cancer have been on it for about 8 months. The joint pain is getting worse, particularly in the mornings and particularly my ankles. I think my hair has thinned a little and I have put on a bit of weight. Libido is minimal. I will keep taking it because the trial seemed so successful and i have young kids and would do anything to stop a recurrence but the side effects are slowly getting me down to the pint where I may have to reconsider the benefits v's the side effecst. F 52 8 months
7/11/2006
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 5  recurrent breast CA w/bone mets Fatigue, bone pain, joint pain, depression, loss of sex drive and vaginal dryness. Inability to concentrate and make decisions. I have taken Tamoxifen, Arimidex, and Aromisin. So far this is the only drug that has reduced tumor size. The side effects are awful and have a negative effect on my quality of life but thankfully with this drug I still have a life. I guess it is worth it to some extent. F 36 7 months
7/2/2006
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 3  her2neu stage 3 I have experienced overall body aches. Pain in the arm bone and have very stiff and painful hand with frozen thumb and ringfinger. F 49 10 months
6/26/2006
 3  recurrent breast cancer 2 months taken hair loss, pain that makes me feel 90 years old, especially in lower back. Nausea, Migraine with Vomiting and diarrhea UGH!!! Is it worth it? 2 years of surgery ,radiation , chemotherapy and Arimidex which failed to keep cancer away. Now on Femara which is getting worse instead of better. Why isn't quality of life a factor ? F 56 2 months
6/22/2006
 3  prevent breast cancer reacurrance weight gain, some hair loss,major hot flashes and sweating,trouble sleeping,aching joints especially upon waking in the morning. Can hardly walk down the stairs. Pain mainly in my lower back and hips especially after sitting for awhile. Have to wear shoes all the time otherwise my feet hurt when I stand or walk on them. I completed 5 years of tomoxifen with no problems. I recently had a hysterectomy that included the removal of my ovaries as a preventative measure. I felt great after surgery prior to taking Femara. I have only been on Femara for two months and I don't like the way I feel. I feel 20 years older and can barely get around without being in some pain. I have heard some many good things about this drug but I question myself as to whether its really worth it. F 44 2 months
6/21/2006
 2  breast cancer treatment painful joints, especially knees, carpal tunnel w/numbness and tingling in fingers I had been taking this med (along with Actonel) for almost a year before these side effects began to make me miserable. I was unable to walk and carry on normal daily activities. Taking Celebrex helped, but my Dr. advised discontinuing Femara and trying Aromasin (with Boniva). Since stopping Femara I have improved. Have not taken the Boniva yet. F 43 1 years
6/13/2006
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 1  High risk according to my doctor fractured hip, degenerative arthritis, fractured foot, achilles tendon separation, very painful joints all over. Weak wrists and all joints. Weight gain. No libido. Swollen legs. Elevated parathyroid levels. Bone density fine. all lab work came back normal after stopping med. On it only 4 months 1 year ago and still suffering a lot of pain. Going to physical therapy and pain clinic. My breast cancer was 20 YEARS AGO!!!!! No chemo, no radiation, just mastectomy. Why started med now is a mystery to me. F 55 4 months
6/12/2006
 4  Breast Cancer Initially very severe hot flashes both during the day and night; would wake up at night just soaked. Have been on Femara for about 1 1/2 years. Hot flashes have decreased, now only an occurrence a couple of times a week. Joint pain, pain in hands and pain in calves is very problematic at times. Very difficult to get up out of chair or to walk down stairs. Especially painful to get up after sitting in car for about 30 minutes. Aleve helps to some extent to modify the pain. Have never taken Tamoxifen; willing to continue with Femara as long as results are good. Recent mammogram and bone density test this week... everything fine Despite the side effects, I'm glad my oncologist recommended Femara which some say is the best drug on the market to inhibit estrogen production. F 61 1 years
6/9/2006
 5  breast cancer 1 lymph nod effected slight hair loss, lost lybido, vaginal dryness, pain in joints, osteoperosis,lost 5 centemeters height, slight weight gain Got relief for most of the side effects by taking Glucosamin, Chondroitin, MSM pills for joints and it helped greatly. Am taking Replens and Ovestin cream for vaginal dryness,and have succeeded in having a sex life, even though less exciting. I have taken Femara for a year and a half after five years of Tamoxifen. No recurrence of Cancer, worth everything. F 74 2 days
5/28/2006
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 4  br cancer with lymph node involved Feet and legs hurt all the time. Difficult to sleep. Hate to take tylenol everyday but that is all that helps. Have not had recurrence. Is it worth it? F 55 1 years
5/28/2006
 4  Recurrence of breast cancer stage 4 Horrific pain in joints especially hips and shoulders. Some pain in back as well. Knees sound like bubble wrap. Can't get out of chair after sitting. Stairs are killers. Must use rail to support most of my weight. 15 pound weight gain. The tumor markers have dropped significantly. Recently researched joint pain on the internet and came across apple cider vinegar. Doc says it's OK to take, so I've been on it about 2 weeks now. What a MIRACLE!!! As long as I take it faithfully, the pain is minor and sometimes not noticable. I'm still a little stiff getting up after sitting for long periods, but stairs are a breeze now! I have also lost 7 pounds. 1 tablespoon in a small glass of water 3 times daily. (start lower and work up to avoid intestinal problems) Be sure to rinse your teeth afterwards. Acid is hard on enamel. F 47 9 months
5/23/2006
 4  breast cancer hot flashes, severe joint pain, loosing hair, depression using it before surgery and it works shrinking the tumor F 57 5 months
5/22/2006
 3  STAGE 1 BREAST CANCER HAD BEEN ON TAMOXIFEN FOR ABOUT A YEAR, THEN HAD TO HAVE ENDOMETRIAL ABLATION BECAUSE OF TAMOXIFEN CAUSING ENDOMETRIAL CELLS. WAS SWITCHED TO FEMARA WHICH HAS CAUSED JOINT PAIN IN KNEES AND BACK, NOT TO MENTION THE HOT FLASHES, SO FAR CANCER FREE, THANKS BE TO GOD. SO I GUESS IT WORKS. M 66 90 days
5/15/2006
 4  breast cancer with bone mets "warm flashes" not hot flashes, vaginal dryness I love being able to take a hormonal drug vs. chemotherapy. F 55 6 months
5/12/2006
 1  breast ca Following Tamoxifen,for 3+ years, switched to Femara. Had lumpectomy, one week later modified mastectomy w/20 sent nodes removed. Chemo, radiation, then advised I could not have reconstruction. Femara was over $300.00/month. I am disabled with no insurance. Have developed trigger fingers (needing surgery) in the right had with Dupretren's contracture in dominant left hand. (No family history) Now have chronic neck, left arm, left knee and swollen joint first ray of right foot. I have zero energy, lethargic most of the time. O sex drive, hair loss and extremely dry skin. I was without Femara for almost a month when I finally had Medicare Rx pick up this prescription. Had hot flashes (status post total hysterectomy for ca) and became extremely depressed,without Femara. I will stay on it as I've been offered no alternative My sister just had her breast removed. I am almost 6 years out. Today I was told that I have severe osteoporosis in my hips. Until I read these other ratin Please find something equal without such discouraging side effects, or address a protocol to lessen them. There seems to be enough similarity in symptoms to generate a serious study. F 57
5/12/2006
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 4  breast cancer met's to liver pain in joints, difficulty getting up from chair, stiffness ,mostly when getting out of bed,most pain in hands knees.does not disturb sleep at this time. i have been on famera for 7 months.i feel i have good quality of life.i am greatfull for this medication,even with it's side affects.It is the only treatment i have been on since diognosis.i had mastomectomy. cancer spred to liver at diognosis.had mri after taking famera for 4 month.3 small liver lesions gone,and the one that was 2 and a half cm. has shurnk to 1 and a half cm.i am very happy . so far side affects are worth it. F 62 7 months
5/7/2006
 3  BC Post tamoxifen 4.5 yrs Joint pain, primarily in hip/pelvic area after about 5 months on the drug. Getting up in the morning or after sitting is very painful - feel like an old woman. Recent dexa scan showed some bone loss, but investigating other causes I was on tamoxifen for 4.5 years, oncologists switched me to femara. Had bad side effects with tamoxifen (weight gain, leg pain all the time, fluid retention). Femara has been much better, but the joint pain/bone loss troubles me. I see my onc in a couple of months and will discuss pros/cons of staying on. I exercise regularly - femara has not affected my ability to do that F 55 15 months
5/1/2006
 1  2nd Cancer-Tamoxifen 4-1/2 years. SWEATING, back and hip pain, tingling in fingers, skin problems-fingers peeling, fatigue, MORE SWEATING (not to be confused with hot flashes) upon ANY exertion I would like an answer about POST-FEMARA effects. I took it for four months after 4-1/2 years on Tamoxifen. The sweats upon any exertion(not to be confused with hot flashes) were so bad that I had no quality of life....dripping from my hair actually, fatigue,night sweats, joint pain. Doc said to stop it. SINCE THEN, the sweating stopped, but my scalp became very oily and itchy, and breaks out so much that I have trouble brushing my hair sometimes---my skin itches all over, and I have gained 15 POUNDS. WHY? M 75 4 months
5/1/2006
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