FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  prevent recurrence of BC swollen feet and hands in the morning, sore joints, acid reflux, hot flashes. Although none of the pain is chronic, every day I feel pain somewhere else: the elbow, the wrist, my hips, my knees. My oncologist told me the symptons usually fade after 6 months but comments from other patients make me think otherwise. F 46 4 months
25 1X day
4/8/2010
Patient History
 5  Stage 4 metastatic BC/bone mets Still having bone pain, especially lower back and pelvis area, but that's also where I had radiation due to mets. All other symptoms have receded, or have become more easy to handle. Have actually been on 8 and half years. Hi Folks! Just wanted to continue to encourage those of you who are still on Femara. You will find my previous comments from a year ago here--dated 4/24/09. Still in complete remission! Yahoo! Most of the side-effects are due to Femara actually working. It's not the drug that's the problem, it's the lack of estrogen. Catch-22 still, I'm sorry to say. Still rating it a 5! Continued Best Wishes to All in our common struggle for survival! XOXO F 55 8 years
25mg 1X day
4/2/2010
Email
 2  BREAST CANCER I FEEL HORRID. WISH I COULD TAKE SOMETHING TO HELP BUT WITH HAVING LUPUS AND A BLOOD CLOTTING DISORDER THERE SEEMS TO BE NOTHING I CAN DO TO HELP MYSELF. SO GLAD I FOUND THIS SITE. I HAVE ALL THE SIDE EFFECTS EXCEPT THE TRIGGER FINGER SOME TALK ABOUT.GOING TO CALL THE FEMARA NUMBER AND TELL THEM HOW BAD I FEEL.1 800- FDA-1088 F 53 4 months
2.5 1X day
4/1/2010
Email
 3  stage 1 breast cancer All of the side effects that others have described--Am now off of it--hope my life will return--The one thing no has talked about is having your hormones checked. I have had it done, paid by me, and found that they are truely suppressed. Therefore, the likelyhood of cancer returning was small. Now I'm off the femara, and I hope to lead a normal life. I, too, was grateful for the drug, however, at what price? I could have cried when I read of other women having the same experience that I have had with the side effects. I, too used every alternative healing I could do. I became a Reiki Master, and I believe with Reiki and alot of mental work, I survived the 5 years on this drug. I'm 67 years old. Joy to all women who are on this drug. Hopeful, someday no woman will have to take it as there will be a cure. F 67 5 years
2.5 mg 1X day
3/25/2010
 2  (stage1) left breast,nodes clear. Memory loss and mental confusion: Vaginal Dryness:Nervous disposition, lack confidence. Some Insomnia:Weakness,(no energy)tire quickly.Depression.Dry eyes; Would like to stop taking this drug but Oncologist insists that a re-occurrence of a cancer tumor would be fatal, this is a catch 22 situation.Continue the drug and be a long time walking dead or stop the drug, live a little, and be dead sooner.Tough decision but I'm considering it! Got to wonder where the years of billions of charity dollar donations for research have gone, to finish up with these miserable results. F 79 30 months
30 MG 1X day
3/23/2010
 2  Early stage BC with bilateral mast I experience very stiff joints at the present time. Hands, knees, hips, feet...I started exercising after my last surgery 12/29/09. It doesn't seem to ease the pain at all. I am also experiencing some memory loss, loss of sex drive, hot flashes and night sweats. I haven't spoken to my Oncologist about the side effects yet I have been fortunate enough to receive sample prescriptions, and not have to come out of pocket, however, I would caution anyone else who does this, there is a registration and when your prescription is filled, it is noted as a registered user of Femara. Make sure you are telling your Oncologist if you are receiving samples. F 47 2.5 months
30mg 1X day
3/10/2010
 4  Stage II - lymph nodes clear No side effects first 5 mos. Then left hand middle finger started popping and hurting when waking. 1 yr in general stiffness upon waking but can walk it off. 1 yr 6 mos in left wrist at base of thumb started aching. 5 days ago woke up with low back muscle spasms for no reason. 3 days ago started taking Aleve and it helps. I adore my oncologist but she is clueless when it comes to openly discussing the side effects of Femara. She just knows that her patients who take it have lower reoccurence rates. I'm thankful for medical advances for obvious reasons. For me, proper nutrition and exercise help and I will continue the Femara with no reservation. F 51 2 years
2.5 mg 1X day
3/7/2010
 3  Stage II Breast Cancer yr 2000 Pain in ankles when getting up in the morning; hard getting up after sitting for 20 minutes or more; lower back pain comes & goes but has been worse the last 3 weeks; can hardly get up; and can't remember things; some bone loss; bad vaginal dryness After taking Femara for 5 years, will the side effects go away when the drug is stopped??????? If someone has been off for 6 months or more please comment. Thank you. F 62 4 years
2.5 1X day
3/3/2010
 2  breast cancer with matastasized bon depression,stomach nausea,joint pain in body,anxiety,depression,rashes,hot flashes F 49 3 months
2.5 1X day
2/26/2010
Email
 2  bc reoccurence (bone mets) headache, insomnia, hot flashes, dry eyes, acid reflux, dizziness, trouble concentrating, memory loss I've only taken it a month, but I miss the Tamoxifen I used to take for two years (unfortunately I'm resistant to Tamoxifen so I had a hysterectomy and now the Femara). I hope the s/e get better as I go along, but I'm ready to jump ship on the Femara! F 34 1 months
1X day
2/24/2010
Email
 3  Breast cancer, mastectomy Nausea, joint pain, sleeplessness, dizziness, chest pain, tired, weakness on my entire right side, severe memory loss Side effects began immediately, and the pain has increased. Memory loss is very scary. I have developed lymphedema, and just checked the 'side effect' information again. Fluid retention is on the list. I have worked my way off of Celexa, which is presribed to help you deal with the pain. I was referred to a Certified Lymphedema therapist, and have been working with him for 6 months now. The diet changes he recommended included taking cod liver oil, it relieves the joint pain; taking vitamin C; and removing dairy products from my diet. It helps. I needed to add exercise to try to regain some strength in my body. I just began Qigong, a form of Tai Chi. This is a another step on the giant learning curve I've been on for 2 years now. I will become an active participant in getting well, no more passive patient. I will reduce the number of drugs going into my body. My oncologist just looks at me when I tell her what I am going through; my GP has admitted that doctors prescribe meds. That's their job. I am going to stop taking this drug. I agree with so many who commented before me, there has to be quality of life. Look at the holistic alternatives, seek advice. God Bless. F 57 19 months
2.5 1X day
2/21/2010
Email
 3  Breast cancer difficulty sleeping, severe hair loss, joint pain, lower back pain, mood swings and memory loss F 59 3.5 years
2.5 mg 1X day
2/21/2010
 4  Stage 2 breast cancer 3 years ago Joint pain at first but it subsided. Slightly thinning hair. Maybe some weight gain, but not a lot. I have been fortunate in taking this drug, but I also take numerous supplements to counteract known side effects. I did have osteopenia in my hips but took Life Extension Bone Restore and KoAct, and last bone density showed no osteopenia. I also take super curcumin, lots of vitamin D3 and other supplements. I hardly feel the effects of Femera. Am hoping it is as successful at preventing a recurrance as advertised. F 63 2.5 years
2.5 mg 1X day
2/20/2010
 3  Early breast cancer Hot flushes, progressive pain/stiffness in hands and feet (hands worse early morning - feet if i am off them etc), loss libido, low energy, memory retention and recall bad. Feel I have aged so much, has affected my life significantly in areas but trying to be positive as do not like possible alternative of return of cancer. No chemo other than Herceptin, radiation and femara. My feet and hands feel like they have fluid build up at times and as well as the joint pain and stiffness. F 52 9 months
2.5mg 1X day
2/12/2010
 2  Breast Cancer Eyebrows almost gone, hair seems thinner,the worst is my hands swell up and it hurts to bend my fingers. My feet feel like wedges are being driven between the bones, so walking for exercise is out. Hot flashes, mostly at night, and numbness in my arms while trying to sleep. I can't live like this for five years. My oncologist said I have to take it and that tamoxifen will give me blood clots. She is very unsympathetic but I think I will have to threaten to stop taking it to see if she will come up with something else. Chemo was awful, but at least I knew it was going to end! I'm afraid this will do permanent damage to my joints and I feel like I'm 90 years old now. What's the point of living longer if you feel miserable the whole time? F 57 5 months
2.5 mg 1X day
2/12/2010
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 3  prev breast cancer recurrence heart pounding, newly diagnosed high blood pressure, joint pain in hips, legs, shoulders and hands/fingers, fatigue, general weakness/tiredness, drenching night sweats, liver counts are now being watched..ALT&AST counts rise every month and now iron count is very high.... F 44 3 months
2.5mg 1X day
2/11/2010
Email
 3  breast cancer severe insomnia,depression, anxiety, fatigue, memory and thinking problems, sex impossible due to dryness....general loss of quality of life I cannot fathom another 5 years on this drug. What would be the point of living? F 70 4 years
2.5 mg 1X day
2/10/2010
Email
 2  breast cancer My major complaint is joint pain, especially in my hands. Thumbs began to get nodes on them. Went to orthopaedic doctor who said I have arthritis. No family members ever had it. On occasion, have awoken to find that my hands are clenched. I also have flushing on my face that comes and goes. What is troubling now is that my cardiologist told me that I have thickening of my heart wall. During the last month I have had pounding sound ( heart beat sound) in both ears. HAS ANYONE ELSE EXPERIENCED CHANGES TO THE HEART OR POUNDING IN EARS? I decided to take a week off from femara to see if the ear problem stops. I am struggling to weigh whether the benefits outweigh the known risks and more importantly the unknown risks. F 56 9 months
30 mg 1X day
2/10/2010
Email
 2  Breast Cancer During course of Femara, experienced soreness in fingers and toes, curled toes, etc. After stopping, toes have started to uncurl, but I've experienced general body weakness. Climbing stairs is more of an effort now. What long term effects does Femara have on the body? I have far less energy post Femara than before. I'm hoping never to have cancer again and that the Femara has indeed helped in that quest. F 63 5 years
30 mg? 1X day
2/9/2010
 3  prevent recurrence of brst cancer severe aching of joints, especially knees and hips, acid reflux, trigger thumb, extreme vaginal dryness (inside and out), lack of libido, hair loss, insomnia, hot flashes I have torn both rotator cuffs in 2 mos., but don't guess this is related, is it ? I haven't had a recurrence of cancer yet, so I am hoping that this means it's working... F 55 10 months
2.5 mg 1X day
2/6/2010
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