FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  stage 3 breast cancer Right thigh muscle pain, left upper back muscle spasm and bone pain. Keeping cancer away I assume so keep taking it. Feel tired all the time. F 60 3 years
30mg
3/24/2015
 4  Stage IV with mets to bone Bone/joint pain like most everyone else. Starting to experience blurred vision, mind fuzziness and dry/itchy skin. I've been on this medicine for a long time and doctor wants me on until it stops working. Currently, I'm still able to go to work everyday, but some days are harder than others. This drug can cause numerous side effects. Most of them are manageable, but some can be brutal. Each person handles things differently. Several years ago, there wasn't as many options out there. Until they find something better, I guess this is what I have to do. F 60 6 years
2.5 1X day
2/13/2015
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Patient History
 4  Stage IV breast cancer, liver mets Hot flashes, complete loss of libido, weight gain, extreme fatigue, muscle stiffness, cramping in legs and feet, hair thinning, neuapathy in hands. Tried Femara five years ago when I was only a stage 2 breast cancer. Couldn't tolerate it and refused it. Now I am a stage IV w/liver mets! Ladies, if it is working please try anything you can to tolerate it. After my first couple days of Femara the second time around I thought I couldn't stand the muscle stiffness but read to take magnesium to help with the muscle stiffness and it has helped! So does exercise even though you don't think it would help, stretching really helps! I will say the side effects seem to get worse the longer I am on it but it sure beats the alternative! F 54 10 months
30mg 1X day
2/6/2015
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 2  breast cancer - stage 1 Severe bone/joint pain; arthritis and increased wear in joints. Pain in feet upon rising feels like walking barefoot on sharp rocks. Insomnia is shredding my quality of life - it's getting harder to function every day. The only way I get at least 3 hrs sleep is to take a sleeping pill which I try to limit to 3 -4 nights a week. I've become good at faking life, except I can't hide the stiffness/joint cracking and difficulty. Libido is at zero. I'm afraid to stop taking this drug because the cancer might come back, but I'm afraid to keep taking it too. I wish there were more options. F 57 2 years
1x day
1/25/2015
 3  Breast cancer Bone pain, legs, feet and back. Trigger thumb, recently feels like tendinitis in left forearm , symptoms seem to last about 6 months before it mores to another body part Hate it, but want to keep cancer away Will stop at 5 yr mark F 56 3 years
2.5 mg
1/15/2015
 1  LEFT BREAST CANCER severe joint pains, lately blood clot in left leg forgetfulness, cramps in all fingers, I have ceased taking this medication in the hope I can get a more normal and less painful life back again. F 60 2 days
5mg 1X day
1/14/2015
 1  Stage 1 breast cancer Severe joint pain especially fingers, back, knees. Fatigue,mood changes, sleep problems, I stopped the drug. I have lost myself . I don't feel human anymore. 5 weeks
1X day
1/6/2015
 2  Post breast cancer. Stage 4 Very tired. Extreme muscle and joint pain. Vaginal dryness and hot flashes. I thought these would all get better but getting worse, but don't want cancer to return. F 54 5 years
2.5 1X day
12/30/2014
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 4  endometriosis hot/cold flashes, vaginal dryness, low libido, weight gain, easier to fatigue - this has impacted my workout and running abilities. I'm taking this in combination with norethindrone (a progesterone) and calcium suppliments to reduce the risk of bone density problems. I no longer have periods, my ovaries aren't producing painful cysts anymore, and all of the endo pain has vanished. The pain relief is so amazing, that I'm working through ways to handle the side effects which is mainly more exercise despite not feeling like it. Exercising regularly has been the #1 thing that's helped keep the other effects at a minimum.. The hardest thing to deal with has been the hot/cold flashes. I don't know what to do about that - exercise doesn't seem to make a difference (except that the hot flashes DURING exercise are no fun). F 39 3 months
2.5mg 1X day
12/20/2014
 1  Stage 1 Breast Ca This stuff is POISON. With 2 days felt nausea, mood swings, heart palpitations, headache. I kept hoping the effects would level out, but they got worse!! Depression, relentless inferno hot flashes insomnia and feeling hopeless. No energy or drive to to do ANYTHING!! Brain fog... Then I came upon this website and realized how unbelievably dangerous this med is. Thank God I didn't take it long enough to have permanent damage to my bones, heart and who knows what else I WILL NOT take Femara or any other Estrogen blocking drugs! Would rather die from the cancer than be debilitated from meds like this! Pay attention ladies!!!! F 57 1 months
2.5
12/20/2014
 3  Estrogen positive breast cancer I had a mini stroke 1 month after starting femara. Even though Docs could find no reason for it, my onc wouldn't admit it could be the meds. I had trigger finger in both hands and couldn't make a fist but that went away after about 9 months. I have tendinitis in feet, wrists, and elbows. I have had a stiff neck for 6 months hoping it will resolve soon, massage, hot & cold therapy have helped some. NO sex drive and terrible vaginal dryness. Oncologist just blows my complaints off so don't even mention them any more. Ever since taking this I hurt everywhere. Hope I can quit taking it in two more years! My tumor was oncotyped and it was very aggressive even though it was stage one. I am afraid to quit taking lettizole and I can function day to day. I walk about 3-4 miles at least 5 days a week and do yoga to help with the muscle pain. I had my ovaries removed, no issues but just didn't want to take any chances. Don't need those puppies anyway. Some out there have had horrible side effects, I have been blessed that mine are manageable so I will continue taking this medicine as long as my oncologist tells me to and shout hurrah when I can stop. F 66 3 years
2.5
12/15/2014
 1  breast mets Extreme weakness and cannot even get up. Extreme bone pain in shoulder and arms. Very depressed F 62 4 weeks
one a day
12/7/2014
 1  BC stage 1 Depression. Headaches, bone pain, vaginal dryness, trigger finger, bloating, weight gain around middle, fatigue, insomnia, nausea. I have lost my zest for doing anything because I am too tired and brain stays foggy! Going back to alternative estrogen blockers! This is the second time I've tried this med. I had hoped to react better. Feel great when not on it. Too many great natural treatments out there to continue suffering like this Get Christine Horner's book, Waking the Warrior Goddess. Christiane Northrup's book on menopause and Dr John Lees book What your Doctor won't Tell you About Progesterone. Awful drug F 64 6 months
11/28/2014
 4   Sore feet,insomnia I am stage 1V breast ca with lung and brain mets! Had full brain rad! I am just so grateful for something that work, regardles of aches and pain! F 58 4 months
11/27/2014
 3  breast cancer stage 4 mets to femur Depression, sleepless nights, sudden fatigue, aches and pain in legs and lower back pain and hot flashes. Just hope it works.... I can handle it. I hear women with breast cancer do well with estrogen positive. F 34 7 weeks
11/25/2014
 1  breast cancer stage 2 Severe joint pain in knees, feet, and back. Fatigue and depression. Weight gain and severe hot flashes. F 63 1 years
2.5 mg
11/23/2014
 1  Breast Cancer Severe back and body pain, depression, irriation, get angry very easily, higher colesterol, mood swings, anxiety, tired and weakness in legs, risk pain, this drugs is horrible, cannot continue taking this drug will push me off the edge. Not living a normal life This is a bad drug not good for human consumption. It is a suicide drug. F 60 2 months
2.5mg 1X day
11/21/2014
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 2  Estrogen Fed Breast Cancer Had a bilateral masectomy and chemotherapy. After 30 days on this drug I have had a few hot flashes but really bothered by the sleepless nights! I am so tired more so then when I was doing chemo. I also have a little bit of back pain . Some days I wake up feeling sad :-( My Dr. said to stop the med for 10 days and we will try drug #2. I knew there would be side effects but what I hate the most is being awake ALL night and feeling tired. I am hopeful I will find something I can live with for the next 10 yrs plus. This drug is different for everyone so it is really finding what works for you. Discuss with your Dr. and together you will find something! F 55 1 months
2.5
11/19/2014
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 4  Breast cancer Stage 1 EP+ HER2- Inferno flashes, back pain, joint pain, high LDL Gained 10 pounds. Now developed a twitch in left thumb Right breast mastectomy. Hoping that it keeps a return of breast cancer away although side effects are not fun. I keep walking daily and pray. F 60 2 years
2.5
11/16/2014
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 3  breast ca x 2 was on aromasin and arimidex in past this is better than them but only because am so used to constant pain and aches I don't remember what normal is. Vag dryness is issue but have discharge beige sometimes pinkish terrible odor??? Any one else experience this??? F 63 2 days
1X day
11/13/2014
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