FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Stage IIIC Breast Cancer, Grade 3 Absolutely no joint pain, bone pain, arthritis, etc. I lost 45 lbs. and took up running after I finished treatment and feel like I'm 30 again. Only noticeable side effect is hair loss. I've been receiving 4 mg. infusions of Zometa every 6 mos. for 2 1/2 years to prevent recurrence, so my bones are in great shape. No side effects from Zometa at all. I just celebrated 4 years survival since my diagnosis and am now confident I'll see my son graduate from HS 6 mos. from now. F 57 3.5 years
2.5 1X day
10/15/2010
 4  Stage IIIC Breast CA Bone and joint paint, muscle pain and spasms, muscles sore to touch, peripheral neuropathy, difficulty getting up after sitting, or going up/down stairs. Fatigue. Word loss, feeling vague. I had mild to moderate symptoms until about a year on Femara, but they do seem to be worsening. I dont care, it's tolerable with Advil or Ultram on the worst days. If it keeps the cancer away, I will take it and CRAWL to my childrens' graduations! F 43 18 months
2.5 1X day
10/10/2010
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 3  breast cancer, 2 nodes, her+ daily like I'm getting the flu (muscle & joint aching - esp legs, arms & feet, verge of sore throat, fatigue, hair very slow returning and coming in very thin, vaginal dryness. It's early, but past 12 days no/little muscle & joint pain! Wanted to share, drinking liquid glucosamine from Walmart (Elations, 6 pack for $7) & walla! Much better than taking 8+ Ibuprofen/d. I did 1st day 1 bottle, then 1/2 bottle/day, mixing with cran-raspberry. also for vaginal dryness try KY LiquiBeads(a moisturizer), now to work on fatigue & thin hair - maybe life can be somewhat normal for the next 4 yrs on this stuff F 60 13 months
2.5 mg 1X day
10/3/2010
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 2  Br cancer stg 2 (lobular & ductal) I've had all the symptoms described here: joint pain, hot flashes, memory loss (names in particular; I'm a college teacher, so this side effect impacts my ability to work), thinning hair, and a low white blood cell count, which is apparently unusual (my oncologist said she'd never heard of that side effect, but I did read about it on the company's website). I'm hoping that I can last 5 years on this, as I've only been on it for 3 months. I tried Tamoxifen briefly, but since I had already had abnormal biopsies, my doctor recommended (and I got) a hysterectomy. And I thought the hot flashes from Tamoxifen were bad! I'm hoping this is worth it.... F 51 3 months
2.5 1X day
9/30/2010
 5  Breast Cancer Stage IIIC My last post I designated the rating as 1 which was a mistake..I meant to say 5 as it has helped a great deal, however not without major side effects. which are listed on my previous post....Thank you. F 56
2.5 1X day
9/28/2010
Patient History
 3  Breast cancer Stage 1 Extreme fatigue, short-term memory loss, thinning hair, mild joint pain, mood swings, hot flashes, sweating, elevated cholesterol, increased bone loss All of these side effects are tolerable but they do wear on me. Biggest issue is fatigue and short-term memory loss. That is scary -- is it Femara or is it Alzheimers, sort of thing. Will see my onc next month re: fatigue. Hang in there -- one day at a time. F 58 9 months
2.5 mg 1X day
9/26/2010
 5  Breast Cancer - 1 Mastectomy Thinning hair; weight gain. Overall good health & energetic. Was on ARIMADEX 6 mo. but had extreme joint pain with crippling effect; then TAMOXIFIN 4-1/2yrs happy/pain free. At 5yr mark Dr chose FEMARA for 5yrs/ended 6mo ago. Last 3 yrs on ZOMETA annual iv for bone loss; was switched to Reclast for bone because 10 yrs. in cancer remission & Reclast used for preventing bone loss. Now having bone & joint pain & tiredness, light-headed, these are side effects from RECLAST. I've always been very energetic happy person who is thought to be 10-15 yrs younger. God has granted me these 10yrs in cancer remission & I attribute much credit to FEMARA for this & to the care of a great Oncologist in St. Louis Mo. I was sorry my Dr stopped my Femara when I reached 10 yr. mark on combined drugs. Dr said effectiveness after 10 yrs hasn't been proven. I exercise daily at gym; do lots of volunteer work to keep active. Femara was a very good cancer-fighting drug for me. All drugs have side effects. I try not to read them. F 76 5 years
2.5 mg 1X day
9/22/2010
 1  Breast Cancer Terrible pain in bones/legs and right arm..had broken arm, when I was 29.....and had no pain after healing....I am now 75 and the arm hurts as if I just broke it. My doctor recommended that I try Femara again...this time, (in 2008) I took the pill for 2 days and on the third day, I could not get up from my chair for over two hours. I never took the pill again...and, the doctor agreed with me. I recommend this pill for all enemies of the free world. This would tell them, that, we mean business in our search for peace. This pill is more devasting than a roadside bomb...at least when you're gone, you're out of misery. But, having to have pain every day is something you'd wish on your worst enemy. My doctor yielded to my discomfort (a mild word) and, I did not take this pill from Hell, again but, it's still rendering terrible pain. I realize, it's probably out of my system, but, the havoc it has caused is still with me. I have contacted the makers of this Hell-Pill to no avail. F 75 12 days
1X day
9/22/2010
 1  Stage 1 breast cander I'm just curious if anyone taking Femara has had frozen shoulder (adhesive capsulitis). I took Femara 3 mos. but was unable to continue because I could not tolerate the side effects. I had ALL known side effects to the medication. About two months into it, I developed frozen shoulder, which is the most painful thing I've endured since my diagnosis. And I have severe loss of range of motion of my shoulder/arm. Anyone one else develop that? My radiation oncologist thought it was triggered by Femara. I've now had frozen shoulder for 4 mos. M 50 3 months
1X day
9/22/2010
 3  breast cancer...stage 2 pain in extremeties Had been on Arimidex. Couldn't stand the bone pain from that after about 4 months. Switched to Femara and had been much better, but over time, the pain and swelling in hands/feet got worse. By the 9th month nearly unbearable to get up in the morning...almost falling over. Stairs were a challenge. At 11 months, asked oncologist and I went off Femara hoping to get relief. On the 15th day w/out Femara, the pain lifted. Still have some swelling and achiness, but the PAIN is gone. At least it was not permanent. Not sure what to do now, possibly try Aromisin? Seems like that is last possible AI to take? F 55 11 months
2.5mg 1X day
9/21/2010
 4  Stage III breast cancer Slight weight gain, generalized aching helped by Glucosamine/Chondroiton triple strength 2 daily, flax-seed oil for increased cholesterol, am having difficulty right now with extremity pain, unexplained injuries to bone and cartilage. Am using tylenol arthritis for aches and pains, developed pre-ulcer condition with NDSAIDS. I intend to keep taking it: if it helps extend my life, I will put up with the thorns. F 59 2 years
2.5 1X day
9/19/2010
 2  Stage 4 Met. Breast Cancer More bone pain. Have had difficulty exercising because it is easy to injure cartiledge or muscle. Not fun. F 54 50 days
2.5 mg 1X day
9/18/2010
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Patient History
 4  Metastatic breast cancer to bone Extreme joint and muscular pain esp. in hands, hips, and knees. Was also on Zometa and have been off for 3 months but pain has not subsided. Insomnia, stiffness and pain comes and goes but is more prominent about four hours after taking meds at night. Hip pain limits movement, walking becomes difficult, steps are hard both down and up. Within 12 months CA27.29 tumor count went from 743 to 53. MRI and CT's initially showed several areas in lumbar with cancer . After 12 months MRI does not show any signs of cancer. Was told I would have to stay on Femara indefinitely as tests are not 100%. F 62 13 months
2.5Mg 1X day
9/16/2010
Email
 4  Stage 1 breast cancer hormone rec + Knee stiffness and moderate pain, swollen, stiff fingers in AM, Swollen feet all day. Having hot flashes - but I was having hot flashes before all this started.I feel 85% better than when I was on Arimidex which made me feel absolutely terrible - all the terrible side effects similar to the postings for Femara . After being off Arimidex for 1 week and starting on the Femara (thanks to my onc who was looking out for me and suggested trying the switch to Femara before letting me give up) I had 50% less side effects. After being on Femara for 45 days I feel about 85% better - I hope it continues Fewer side effects than Arimidex. I am taking COD LIVER OIL 3x a day for hotflashes - It has really helped cut down the frequency, duration and intensity. I hope you all can find the relief I have - it is great to have most of my life back and still know I am doing the most I can to keep this disease from coming back. F 59 45 days
2.5 mg 1X day
9/10/2010
 4  Hormonal induced breast cancer Very tired, arthritic type aches, swollen joints, if sitting for a while, when I get up it takes a few seconds to move properly. Low libido and very dry vargina, due to estrogen being drastically reduced in the body. Hair is very slow at growing and is very thin. F 60 365 days
1X day
9/8/2010
 4  stage 3 breast cancer Has anyone have dental problems. Went to dentist and was told I am having cavities at the root level, sore muscles, not sleeping very good F 72 18 months
2.5 mg 1X day
9/8/2010
Email
 2  br ca stage IIB, er+pr+her2+grade 3 Sore throat, fatigue, memory problems, lethargy. Wanted everyone who's on this to know about Novartis' $10 per month Femara cost for prescription for one year. You can get a one-year free Femara discount card from Novartis Pharmaceutical and pay $10.00 a month. F 55 15 days
2.5 mg 1X day
9/6/2010
Email
 4  Breast cancer joint pain, hair loss, insomnia, sweating, weight gain,gerd,high cholesterol,bone loss, dizziness, fatigue hated taking it, made me feel 90 years old. difficult to get up and start moving. But, I am still NED after almost 10 years. F 57 7 years
2.5 mg 1X day
9/2/2010
 4  Bi-lateral Breast Cancer Severe Fatigue, mild high cholestrol,severe joint pain in knees, hips, elbows, hands & feet. Blurry vision, focus issues, forget full, very difficult to work. To manage my chronic pain & neuropathy in my feet I am on an extended release 5.0 mg of a mild pain pill called Tramadol.I have been taking this for about 8 months & it has given me back my life. I am able to do most things without pain. F 53 29 months
2.5 MG 1X day
9/2/2010
 3  breast cancer I've had trigger finger surgery on 4 fingers, carpol tunnel surgery, fingers are swollen and stiff in the morning, when I've been sitting a long time I have trouble standing and walking. I also have a cough. My doctor doesn't think it is the femara. I have 2 more years to take it. F 62 3 years
2.5 mg 1X day
9/2/2010

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