GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  high blood sugar none noted. hard to tell due to the girth of other meds due to brain tumor. Metformin does not work yet Glucophage does. M 61 10 years
5/3/2009
 5  pre diabetes sometimes a little acid stomach which is remedied by eating a small protein snack, nuts or something. Loose bowels once in awhile, no big deal. Smellier gas, but so what. My glucose readings have improved a great deal. I have lost no weight despite eating little and exercising regularly. But having better readings is great. So far haven't experienced hair thinning. Have been on it for about 6 weeks, 500mg extended release. F 63 6 weeks
5/1/2009
 5  Type II Diabetes Mild nausea starting dose was 500 and I also take synthroid for hypothroidism and between both health issues I was having difficulty losing any weight. I work out 3-5 times a week at a high intensity and nothing changed. Doc upped dosage to 2000 a day and so far so good, no side effects and I'm losing weight F 45 1 years
4/22/2009
 3  Type II Diabetes none so far Just started taking metformin today..starting to feel bubble guts but no diaherra..was diagnosed yesterday and my a1c number was 12.8..i guess that's really bad..all this is new to me..also my blood sugar was 235 after only eating a sandwich and a couple vitamin water bottles..i need all the advice i can get M 31 1 days
4/21/2009
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 3  Diabetes type 2 Doc started me on 1000mg Glucophage x 2 a day, i.e. 2,000mg a day. Within a week my blood glucose (on a low-carb, almost no-carb diet) started dropping to almost normal levels. But also, then came the gastro-int. effects everyone mentions -- and then I noticed the hair loss. This was devastating as I have babyfine hair. I lost 12 kg which was really enough. I cut back to 1 x 500mg tablet per day. The GI symptoms went away, my bs went up! The hair loss, after taking $$$$ of supplements, slightly reversed itself after 12 months!!! But my bs went up. Unfortunately, because my last A1C came back as 6.1% (on the edge of normal) I decided to add back another 500g Glucophage ... One tab in the morning, one at night. I've been back, therefore, on 1000mg a day -- and after 5 days my blood glucose has dropped ... and so is my hair: falling out again!!! I'm between a rock and a hard place: either I risk the higher blood sugar, or I keep my hair. I'm a woman. The choice is simple: I'd rather keep my hair, which is thin and soft enough. Yikes. (By the way, I am now on the XR (extended release) tablets. There seems to be no diff. between the 2 types). F 67 15 months
4/12/2009
 2  I.R. I am haveing alot of bathroom problems..i always always have to know where one is or my chances of haveing an accident are high. I feel constantly sick to my tum. Before I started taking this med. i had regular periods...but now mine is missing?? I dont know if this is a normal side effect or not? F 25 2 weeks
4/7/2009
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 1  Type 2 diabetes Diarrhea. Don't believe anyone who tells you that you might experience episodes of diarrhea which will go away as "your body adjusts" to this drug. In my case, it was the opposite -- no problems at first but gradually over a period of many months I started experiencing episodes of diarrhea. Eventually it became almost a continuous ocurrence -- I had to always be aware of where the bathroom was everywhere I went. It got so bad that I even ended up taking Immodium as a precautionary measure every time I got on a plane or took a long car trip. I began to wonder if I had Chron's disease or IBS. Never related it to the Metformin since I hadn't had problems to begin with. Then I saw a gastroenterologist who suggested I try stopping Metformin. Within 48 hours I was totally cured! And have been normal ever since. This is a horrible drug. M 60 2 years
4/1/2009
 5  insulin resistant really bad gas...and occasional diarrhea....other then that this pill is a miracle!!! where do i begin...after not having a period for 3 months i went to my doc for some blood work and found out i was insulin resistant so she prescribed metformin. i take 500 mg twice a day with meals...i have totally changed my eating habits and along with walking every other day i have lost 20 pounds in 3 months! and not to mention my periods are regular again. i have so much more energy...and it has also cleared my acne....its a miracle pill!!!!! F 22 3 months
3/27/2009
 2  High A!C and Dysautonomia Gained 15 pounds first 30 days. A1C dropped first 6 months then increased to highest ever next 6 months (2 full points from 6.0 to 8.0) F 65 1 years
3/17/2009
 5  newly diagnosed type 2 diabetic The first day I took the meds I had explosive episodes in the bathroom. I went to the bathroom 14 times in one day with bad cramping and well, you know. If I did not get to the toliet in .98 seconds, I was in trouble. I had read all the posts prior to taking the meds to prepare myself and thought to myself, oh boy I am in for a ride with these meds. HOWEVER, the next day I had NO side effects and I have not had any side effects whatsoever since that first day ( I am using the time release XR version) It's been 16 days and I am very thankful and pleased to report that I guess the drug does not produce severe side effects in everyone. My sugar level has come down very nicely together with radically changing my diet and incorporating excersise into my life. Over all I have no complaints and would encourage you not to get overwhelmed by the various reactions because it may not affect YOU the same way. M 39 16 days
3/13/2009
 4  PCOS QUESTION: I have taken two of these pills, yesterday at three and this morning at eight and I don't have side effects yet. Can any of you tell me when you first started having the SE's? Thanks! QUESTION: I have taken two of these pills, yesterday at three and this morning at eight and I don't have side effects yet. Can any of you tell me when you first started having the SE's? Thanks! F 27 2 days
3/12/2009
 5  P.C.O lol @ farts, Glucophage has what I call trigger foods, certain foods will add to the um smell or amount of em. You learn to kinda play with when to take it (ex. dont take it right before eating pizza lol, you'll regret it, well ok the ppl in the room will lol) Not sure if ask a patient will allow this link, but this was a story they did on my weight loss with glucophage in our local paper AJC. Glucophage / Metformin can be a pain in the butt to get use to but Trust me yall, its worth it !!!! www.ajc.com/services/content/health/stories/2009/03/02/weight_loss_success_Powell.html?cxtype=rss&cxsvc=7&cxcat=9 F 31 2 years
3/11/2009
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 5  Type 2 Diabetes Diarrhea the first few days; other than that, no side effects This has been a wonderful medication for me! In addition to losing 28 pounds with very little effort, I have much more energy now than I did before taking metformin. F 50 120 days
3/3/2009
 4  Diabetes Mellitus Severe diarrhea and some cramps that do not subside over time. I also have moderate hair loss. Sometimes I feel lightheaded. Still it is the only drug that works better for me. I take 1000mg twice a day with Amaryl 4mg I used to take the XR but the reaction was too bad and now take the regular pill. The drug also made me loose weight I had gained when taking Avandia, it was a dramatic change in very short time. M 58 2 years
3/3/2009
 4  PCOS w/IR I presently feel really good. I have only experienced 2 negative side effects- 1 being gas that is more prevelant approx. and up to 9 hours after taking. I fill a little bloated but nothing that is effecting my clothing. 2nd would be becoming extremely hungry if I don't eat something around every 2 hours. The further away I get from taking the pill the less prevelant it is, which I assume is because the meds are working out of the body. On a happy note this is day 4 and show a 5 pd weight loss already. I am overall pleased with my bodies response to 500 mg once a day. My dose will go up after 7 days then again after 14 days. I only have one concern and that is how quickly the weight is coming off. I have noticed a lack of desire to eat sugary or starchy foods. I don't have a problem eating meals I am just making healhy choices when I do. I did loose weight from 2002-2004 (60 pds) but it was the hardest thing I have ever done in my life. I worked hard labor and exercised a minimum of 1 hour a night with a 1200 cal strick diet. I am now praticing 1500-1700 cals a day low fat healthy carbs little to no sugar. I haven't started exercising yet and will add slowly so I don't overwhelm myself. F 31 4 days
2/27/2009
 5  PCOS The Usual GI symptoms listed in the other ratings IE. Farting, Diarrhea, cramps In spite of the Loud Gross Farting (My Husband asked if we were living in FARTVILLE)LOL, Diarrhea and cramps...I must say this is worth it for PCOS. Anyone have tips for the embarrassing/stinky Flatulence? I have never farted so much in my entire life! Still worth it though! F 32 3 months
2/26/2009
 5  t2 diabetes first 2 weeks experienced diarrhea no cramps it then subsided over a 1 week period I take 500mg 2x a day it has done wonders for my blood sugar and my 6mnth a1c is now a steady 4.5 - 5.0 down from a 7 when i first started taking it 2 yrs ago. I see people with positive experiences on here saying keep on taking it even though it makes you wish you were dead. Um not so much. What good is living if the meds you take make you feel really really bad, or worse. My doctor has always told me if a cure makes you feel worse than the condition, then we need to find a different cure. you and the doctor should be on the same team (team you). You and the doctor should actively participate in your recovery not just the doctor. If you feel this is not the case you should change doctors or become more active in your recovery if your not already. Just my opinion. M 39 720 days
2/23/2009
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 3  PCOS & Insulin Resistance Hair loss, Diarrhea, Thyroid Issues. Explosive diarrhea, Loss of appetite, weight loss, nausea, hair loss, no real change in blood sugar levels even on a strick diet. Occasionally get extremly tired after taking metformin. My thyroid levels have been abnormal since taking this medication. Not sure if it's from the medication or not. I also noticed that I wake up with dry mouth and tend to be thirsty more. F 40 180 days
2/22/2009
 4  PCOS A little bit of loss of apitite and I am drinking more water than I used to (but I drink a lot of water already) This is my second time starting this medicine. The first time was a year ago and it was the extended release version. I quit after 1 month because of the stomach cramping. After my sister who also has PCOS got pregnant using it I decided to give it another try. This time around I am on the non extended release at 500mg 2x a day. When I went on it the first I had done a lot of research before ever taking it so I knew what kind of side effects the medicine has. With both times starting out I also took it along with and anti-diarrhea pill. This combination keep me from the dreaded diarrhea side effect. This second time around my doctor gave me and anti-nausea pill to take the first two weeks until I get used to the medicine. The combination of the three medicines has keep me side effect free. F 33 7 days
2/20/2009
 5  insulin resistance I have had none of the side effects described here. None of the intestinal problems, headaches, nothing. In fact, I have more energy and feel better than I have in a long time. The best thing is that my appetite has decreased, and I have lost ten pounds since I started taking metformin. Also, my cholesterol dropped by 11 points. I take 1000 mg. a day. One in the morning, and one in the evening. I can't say enough good things about this drug. For me, it has been a miracle. F 50 2 months
2/10/2009

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