GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  PCOS nausea,gas,tired,felt like i was unbalanced I have lost 8 pounds and I'm starting to see less of a brake out on my face. Acne and My weight gain has trouble me for 3 years after the birth of my 3 child. If there are any websites for better communication I love to join! F 38 2 weeks
12/7/2006
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 4  insulin resistance I had absolutely no GI effects. Instead I felt "high" the first month or two I took the drug. I took the XR form, so I took it at night. About three hours before my next dose was due, as the drug wore off I would feel a nervous "itchy and scratchy" feeling. Also, for the first month or so, my thyroid needed less supplementation and my temperature ran higher than usual during the day (99.2). Now I am experiencing the opposite - hypothyroidism and sleepiness that is like I am taking nothing for my thyroid! I have a great endocrinologist, and he said he had never heard of this happening. Please email me if you have an explanation or have had similar results. It helped me lose 15 extra pounds, but the weird thyroid effects and anxiety that nobody seems to understand are troublesome. F 49 3 months
12/6/2006
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 5  insulin resistance and pcos gas, bloating and loose stools. I have been taking the generic form of Glucophage, Metformin for 6 days and already have lost 5 lbs. I am so excited about this drug. I was always a thin person, but started rapidly gaining weight in the last 4 yrs. I am 5'9 and 229lbs. Hope to lose about 75-85 lbs and get back to my old size. F 29 6 days
12/5/2006
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 5  PCOS Nausea I've been taking met for 3 weeks now. 500mg 1st week rising to 1500mg in the 3rd week. I got a period in the second week for the first time in nearly a year. I've also lost 8lbs. F 34 3 weeks
12/4/2006
 3  PCOS I started taking a low-dose four months ago and at first noticed a drop in energy and generally feeling unwell with sore muscles. Vomited first month with other stomach upset. Never had a problem with weight but noticed an improvement in my waist-line and improvemnt with excess hair growth and pms. However I have lost alot of hair on my head which I never had a problem with before taking this drug. My doctors don't see why this would be causing it. It is in a male-pattern so may be from pcos. I constantly have a salty coppery taste in my mouth with extreme dehydration and the contant need to pee. Seen a doctor about this too. Stopped taking this drug four days ago as the hairloss is getting worse, I have constant migraines, bruising, and all over itchiness. Itchiness, feeling of acid reflux, and dehydration gone away. Enery improving. Hoping my hair will grow back. F 24 4.5 months
11/27/2006
 3  PCOS/Insulin Resistance increased tiredness, constipation, headaches, low energy After a brief upsurge of energy at the start (first week), I am more tired than ever (third week). Also, this medication is like a sleeping pill for me. Within 30 minutes of taking it, I cannot keep my eyes open. I am taking 1000mg of Fortamet at night and am leery of adding the second dose to my schedule because of the severe fatigue. F 36 3.5 weeks
11/22/2006
 5  PCOS / Insulin Resistance When I first started taking this medicine (500mg) I would get a slight headache and experience some nausea nothing to bad. I have been on glucophage about a 2-3 weeks now and my dosage has been increased to 1500 mg. I am nervous about that but I am feeling okay. Since I have started I have went from 175.5 to 165. I am thrilled about the weight loss and I am hoping to lose 25 more pounds. I read some thoughts about the diarrehea and I hope that doesn't happen to me. F 21 3 weeks
11/21/2006
 5  PCOS/Infertility No side effects We tried 4 months to get pregnant with no luck. Started glucophage (metformin) and got pregnant the next cycle. The doc advised I stay on the drug throughout the pregnancy to prevent miscarriage (though its not FDA approved yet for such use.) I just started taking it again, hoping to conceive child #2. I feel like I have the flu. I don't know if its the drug or not. I'm shaking, have a headache, feel achy..can't keep warm. Motrin fixed these symptoms however. F 40 9 months
11/20/2006
 5  Insulin Resistance Syndrome After starting metformin, she did have the abd side effects on and off (abd pain, diarrhea) for about 2 weeks, then they decreased sharply. I am a mother of a 6 year old girl, who was 4'6" and weighed 111 pounds. Being a nurse, I noted that she started gaining weight awfully fast and eating constantly. I took her to a Pediatric Endocrinologist and after testing she was diagnosed with insulin resistance syndrome in May 2006. She started on 1000mg with breakfast and dinner. She is now on 500 mg twice a day and, 4"7" and 93 pounds, without any diet change. Her appetite was cut almost from dose one and she is a totally different child, energy for days and eats a serving of food and does not ask for seconds or thirds. This has been a blessing for us. F 35 6 months
11/18/2006
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 5  Type II Diabetes Gas, cramping first couple of weeks. Dizziness, muscle cramps and HAIR LOSS. Periods returned despite previously having an endometrial ablation. Take 500 mg twice a day. ACH1 was over 10, now 5.4. Have lost 64 lbs (90 total) since taking this drug, however, I am on a rigorous diet and exercise program. I don't think it is a "magical" weight loss drug. Hair problems could be due to the tremendous weight loss since this has happened before when I've lost weight, it just seems really excessive. The return of periods is disappointing, but it's nowhere near the severity of pre-ablation. Dealing with it since the good outweighs the bad at this point. F 44 5 months
11/18/2006
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 4  Type 2 Diabetes Gas, Stomach bloating (even after 1 yr.) It does work, but I sometimes miss taking one of the 500mg. doses/day. My blood sugar level has really gone down over the last year. F 49 1 years
11/16/2006
 4  Type II Diabetes some diarrhea in the morning, not as dramatic as others describe. after increasing to 1000 mg 2x day, along with Januvia, had some pain in lower left leg during the night - not sure if this is related? am a little concerned about this as it was a different pain then a leg cramp. been on metformin for ~ 6 months as actoplus, first at 500 mg them 850 mg. Just started it alone at 1000 mg 2x per day, along with Januvia once a day. HBA1c was down to 6.6 before beginning the 1000 mg so I expect it to go even lower now. F 54 6 months
11/12/2006
 3  PCOS tiredness, yawning fits, headaches, extreme hunger Been taking for a month (500mg 3 times a day) and have noticed no improvement or symptoms or weight loss yet. F 35 1 months
11/7/2006
 5  ? Insulin Resistance/Weight Loss Knock on wood, but I have been taking for 2 1/2 months. I take 500 mg q day with breakfast. I experienced no abdominal type side effects. I have had some success. I have lost 16 lbs (176-160lbs) taking Metformin and sticking to a lower carbohydrate diet. During this time I haven't even excercised much, but I need to pick it up again. Before taking Metformin I had a pretty similar diet, and was excercsing, but the pounds weren't coming off t quickly. F 32 2.5 weeks
10/20/2006
 5  Weight , High Insulin level (PCOs?) Stomach upset,Diarrhea and constipation alternatively,Nausea and dizziness for the first few days,Stomach disorder continues... Currently,I have lost 7 pounds in 1 and half months.However I have previously taken this med.I have a history of two pregnancy wastages.My OB prescribed Glucophage after that.My periods were always normal.I was 76KG(167.2pounds)then.I lost 13 pounds,and I stopped the med after taking it for 9 months.But I was not mentally prepared to think of another pregnancy at that time.Meanwhile I again gained weight and this time my insulin(PP) level was really high(138mU/l)but fasting level is within normal range.My doc again prescribed Glucophage.I want to get pregnant again,but will have to lose a lot of weight before that.I am exercising and trying to eat less calories.with the 7 pounds weight loss I am hopefull.I have got a lot of hope from your posts,particularly those who gave birth to their children after being on this med.Wish me luck too. F 30 52 days
10/19/2006
 3  PCOS None I have not lost any weight yet, but heard it would be a few months...still no period which I don't mind, but I guess I have to have one. I am starting to wonder if I do not have a strong enough dosage or if its because im on the 750 XR tablet. Anyone else not seeing anything happen? F 23 2 months
10/12/2006
 3  PCOS I started taking one 500mg pill a day and I started having headaches, bloating, and I was nauseated and experienced vomiting often. I have been on Glucophage for a year and I have lost about 70 pds. I weighed 104 and had gained 80 pds. when they realized I had PCOS after several tests. I am very pleased with how I feel and the weight loss. I have the side effects about every two weeks. F 20 1 years
10/12/2006
 5  PCOS Bloating, Stomach Ache, Using the bathroom constantly. I have lost some weight...Hoping I get pregnant. Weight loss is great too!!! Hope it continues F 29 1 weeks
10/10/2006
 3  PCOS Nausea, severe acid reflux, weight GAIN, bloating (severe) headaches, lowered blood sugar, diarrhea, sudden "emergency" trips to the bathroom. I started on 750 mg and fought the GI side effects for a month or more. They finally disapated with only a few random recurrences. After I gained weight over six months on a strict diet and exercise program, the doc doubled my dose, which I've been on for five days now. All of the GI symptoms have returned full force minus the acid reflux. I am no longer spiking (blood sugar) after meals so I am happy about that. F 26 6 months
10/10/2006
 2  PCOS and Infertility Horrible gastro-intestinal side effects that didn't subside after gradually increasing medication to 1500 mg and staying on it for almost 4 months. I also noticed my progesterone decreased and for the first time I had to take progesterone suppositories. I would not recommend this medication if you have IBS. It really aggravated it. I've been off of Metformin for 2 months and I'm still having problems. F 28 4 months
9/30/2006

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