GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Insulin Resistance Tiredness, headaches, gas, loose stools. Thirsty all the time. And yay it took my sweet tooth away! 500mg Glucophage XR - Glad it has cured my unhealthy sweet and fizzy drink addiction, when willpower alone could not do it. Still waiting to see the scales move though. Watch this space. F 36 18 days
500mg 1X day
9/2/2011
 4  To treat PCOS Horrible nausea, excessive gas, stomach pain, frequent restroom breaks I was prescribed Metformin after I was diagnosed with PCOS. Over the course of 4 weeks I will go from one pill a day to four a day (500 mg each). I'm currently at day 9. The side effects aren't anything unbearable. I've definitely been through worse. The 2nd day of taking this medication, I was in the restroom 4 times, so if you're about to start taking it, be prepared! I was started at a lower dosage because the side effects would be more harsh if I started out at the 2000 mg. I was told by my Dr. that many people can't tolerate the full 2000 mg a day and they have to decrease it to 1500 mg due to the person constantly being sick. Within the first 5 days of using Metformin I lost 6 pounds. F 26 9 days
500-2000MG 1X day
8/9/2011
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 3  PCOS Flu-like aches and fatigue for first 3 days I had relatively few side effects - only mild aching for the first couple days, which could have possibly just been some kind of cold. I'm taking it for insulin resistance caused by PCOS. My periods are still absent and I still have a small amount of facial hair. It hasn't helped those things, but hopefully it's keeping my pancreas from having to work so hard at producing insulin. No real side effects so I can't complain, and it's dirt cheap - $4 at walmart F 22 4 months
500 2X day
6/10/2011
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 5  PCOS Diarrhea & stomach cramps over the 4 weeks buiding up to the full dose (+500mg per week util I reached 2000mg)...but symptoms were eased with a low carb diet It has worked wonders for me, after a few weeks my periods were every 33-35 days (rather than every 3-9 months)...I have lost weight (12 kg to date) but through a low carb diet & gentle exercise rather than the Metformin alone (I think if I upped the cardio & cut back further on the food the results would be more drastic)...I am more energetic and am sure the facial hair is less noticeable....It has transformed my life (and will hopefully enable us to create one in the near future) xxx F 37 7 months
1000mg 2X day
6/9/2011
 3  help with PCOS Doctor increased my dosage from 1000 to 2000 mg of metformin daily... no real side effects except unbelievable diarrhea... thinking of asking the doctor to reduce the dosage F 44 6 months
1000 2X day
6/9/2011
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 2  PCOS The brain fog was terribe. It made me feel like I had the flu. F 30 7 days
500 3X day
4/22/2011
 3  PCOS Severe, emergency diarrhea, nausea, gas, heartburn, acid ingestion. I'm taking it for PCOS. Have been trying to get pregnant for over a year now. I've been on 2 times before and suffered terrible diarrhea both times. This time I'm willing to give it more time. I'll keep you posted. F 33 2 days
500mg 2X day
4/21/2011
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 4  PCOS Diarrhea, nausea, vomiting, bloating, sleepiness, headaches. I experienced terrible diarrhea, nausea, vomiting from this drug, however, if you give it the chance, stick with it for a few weeks, and get through the side effects, they subside, and the results are- for me- ovulation and weight loss. This is very important because not only are my chances of pregnancy increased greatly, but my chances for diabetes and gestational diabetes are decreased because of the weight loss. I suggest it- but you must be patient with the drug. These are KNOWN side effects. If you must, increase more slowly. For me- it was worth it just to increase more quickly because every increase gave me more side effects, so better to feel terrible for 2-3 weeks and be done with it. Than to feel terrible for a week and a half three times for each increase. I suppose it depends on what you are willing to deal with.... F 25 6 months
500mg 2X day
4/7/2011
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 1  PCOS Nausea, loose stools, headaches I took metformin for my PCOS and never lost any weight. I never had elevated blood sugar levels. I am now unable to eat any meat products due to the nausea, and am suffering from a severe vitamin b12 deficiency. Since I quit taking to metformin, I can at least eat what little I can without running to the bathroom. Not sure if this drug caused all my problems, but beware ob/gyns who think this is the answer to PCOS. Now I can't even touch my hair without if falling out or breaking. F 36 7 years
850 2X day
3/21/2011
 4  PCOS/insulin resistance Diarrhea alternating with slight constipation, cramps, stomach gurgling, headaches, bursts of energy I was on this med about 5 years ago. Had similar side effects, except for these weird bursts of energy! It definitely helps with weight loss (the first time I was on it, I lost about 45 lbs along with diet and moderate exercise), which in turn will help lower my chances of diabetes. And that's pretty awesome because I HATE needles. It's worth some of the discomfort to me. F 25 1.5 years
up to 1500 1X day
3/20/2011
 4  early stage of diabetes Slight headache and nausea, frequest bowl movements, slight stomach cramp. Thankful I found this forum, because I was concerned about the symptoms I was experiencing and comforted by the fact they seem to be very common. F 66 2 days
500 1X day
3/12/2011
 4  Insulin resistant/PCOS Loose stool, felt out of breath a bit - this has subsided, sleepiness - subsided, belly bloat - subsided. I take with meals morning and night. I have had no nausea or vomiting. I have had some loose stools, more like regularity. My face has cleared up some. I have noticed that sex is not as intense :( I am not sure about weight loss since it has only been a month. My period has not appeared as of yet. My moods have improved and I don't have that terrible shakiness if I don't eat anymore. My blood sugar (not fasting) was 140 before and now it runs 120 (not fasting). I am going to stick with this for another month or so to see what happens. M 37 1 months
500 mg 2X day
3/6/2011
 5  type 2 diabetes A bit of nausia and loss of appetite until I lost about 30 pounds. I'm sure the weight loss helped me a lot. I am off medication now, but I stuggle to keep my blood sugar normal. Type 2 diabetes is reversable. M 57 9 years
500Mg 3X day
3/5/2011
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 5  Insulin resistance Nausea the first few days, "buzzed" feeling but focused and energized, appetite decrease, less obsession with food, totally turned off by carbs Didn't experience too much of the gastro side effects (I think) because I have been eating minimally processed / paleo / whole foods for several years before starting Metformin. I'm sleeping better and stopped snoring 3 days after starting. I know I've lost a few pounds but haven't stepped on a scale in a while so don't have exact numbers. I do get pretty hungry when it's time to eat but it is a physical hunger. I'm not suffering fogginess or confusion from highs and lows of blood sugar. I am very hopeful. Nothing else has helped me lose this abdominal fat. Will keep you posted. M 47 1 weeks
500mg 3X day
2/25/2011
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 3  Pre-diabetic Almost daily diarrhea and indigestion I have been wondering why I have been having so much diarrhea. I have had problems with it since I have gotten a little older anyway, but it is getting worse. For the last few months I have not been exercising or dieting and eating whatever I want. I think I have finally realized reading these posts that I must cut my carb consumption. I am going to try that and see if I lose some weight and the side effects diminish. I'll let you know! F 50 1 years
500 mg 1X day
2/22/2011
 5  PCOS F 23
1500 XR 1X day
2/19/2011
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Patient History
 3  PCOS/Insulin Resistance/TTC severe diarrhea, occasional constipation, changes in appetite, I can be starving one minute and then completely turned off by food the next, gas, bloating, stomach gurgling, stomach cramps Taking the extended release version of Metformin has really helped with my side effects. Also, taking the medication at night between dinner and bedtime helped me. Originally my side effects were so bad I considered going off the drug. All I can say is stick with it, it will get better. I still experience the side effects, but no where near as severe. I have lost about 8-10 pounds in the last 6 months while taking Metformin (without exercise and without changing my diet). This medication has reduced my cycle length from 45-70 days to 33-36 days. However, I have not ovulated on my own. F 30 6 months
1500 mg 1X day
1/29/2011
 4  PCOS The 1st week I was taking 1 tablet in the evening before bed. I felt dreadful. Tired, dazed, bloated. I didn't have too many stomach issues though. Just felt like I had flu symptoms. Then I upped the dose by 1 more pill in the afternoon and had no side effects. After 1.5 weeks of taking the medication, I felt back to normal. I am taking this medication for infertility. I'm very slim so had no idea I might be insulin intolerant, anyhow, after 2 months all my cysts have disappeared and I'm therefore hoping I'll fall pregnant soon. F 31 2 months
500 2X day
1/26/2011
 3  Insullin resistance Gas, bloating, flatulence, diarrea, occassional naussea and recently intermittent anxiety or feelings of dread. Started taking 500mg a day for two weeks then 1000mg for one month then went up to 2000mg in the morning after breakfast. I noticed that the symptoms of upset stomach decreased quit a bit when I cut out or limit my carb intake to one serving of carb per/ meal. Recently I noticed that the anxiety comes on when the meds peak (around mid-day). It has helped to lower sugar levels but I have to watch my carb intake for it to work. F 41 5 months
2000mg 1X day
1/6/2011
 3  PCOS/IR diarrhea, but also constipation...mostly have subdued but every few days it still happens so i know this is for a review but please please if anyone could answer a question, so i've been excerising at least an hour every single day without fault some days over 2hrs and trying to stay under 1200cal/aday but im not loosing weight? when i get to 2000mg/a day is that when everyone noticed weight loss i feel crazy excerising so much and not eating everything i want when im not loosing weight. Please email me with advice or when u noticed weight loss what your dosage was? F 18 2 weeks
500mg 2X day
12/26/2010
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