GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  PCOS related Insulin Resistance pro: more energy, more focused, BG stable (last tolerance test was 212 after 1hr/ 74 3 hrs later) con: alternating diarrhea and constipation Reading the comments I see that I will have to keep a food diary to see what I'm eating that may cause the GI probs. I lost both my ovaries to cycsts (13 and 16 years ago) but since PCOS is not a problem with my ovaries but rather a metabolic disorder - I still have the impaired glucose tolerance. Lucky for me I had my girls at 18 and 21 - before my ovaries went into severe cyst formation. Both of them have PCOS... thank goodness they've got better solutions for them than ovary removal! F 39 21 days
3/10/2008
 4  PCOS A little bit of diarrhea, but nothing too bad. I feel much better and am more 'clear headed'. I have only been on it for a week, but have lost 3 pounds, which 6 weeks of exercising 5x a week couldn't do. I am very pleased so far. I have more energy and am going to keep taking it. F 27 7 days
2/28/2008
 3  type 2 diabetes Metallic taste in mouth, complete lack of interest in drinking water (I was at 2 gallons a day w/ workouts!!!), some nausea, but the worst by far is the diarrhea w/ cramping. I will give it one more week buts thats it-I can't leave the bathroom to go to work. M 48 5 weeks
2/26/2008
 3  PCOS-related insulin resistance Stomach cramps, diarrhea, thinning hair and hair loss similar to male-pattern balding. Taking Metformin (500 mg x 2) helps ovulate monthly and keeps blood levels under 120... however, a decision needs to be made... period or wig? Searching for a solution that may help with the hair loss. F 41 270 days
2/26/2008
 2  Metabolic Syndrome Nausea, unpredictable and forceful diarrhea, extreme drowsiness and cold right after taking, hungrier. No change in side effects even after a year. They are STILL BAD!!! I've been taking this for over a year. I'm supposed to take one pill in the morning and one at night, but I can't take the morning one or I will have to spend my entire morning running to the bathroom. The diarrhea comes on suddenly and forcefully. If I'm not really close to a bathroom, I'm in trouble. As a teacher, I can't run to the bathroom any time I feel like it so I can't take it at all in the morning. I have been constantly sick to my stomach and much hungrier since I've been taking it. About a half hour after I take it, I get so drowsy I have to sleep. I'm also very cold then too. F 48 1 years
2/22/2008
 2   F 21
2/14/2008
 5  PCOS only good side effects , loss of appetite and weight loss, also return of menses and successful pregnancy! F 28 1 years
2/11/2008
 3  misdiagnosis of PCOS Nausea, loss of appetite, dierriah for weeks, loss of libido, very painful stomach cramps, blood in stools. It helped me ovulate each month, but I had to stop it because of the blood in the stools. As it turns out I didn't even have PCOS and was later diagnosed with endometriosis. F 29 3 months
1/30/2008
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 3  type 2 diabetes Gas, bloating, burping and thinning hair It has helped with my numbers somewhat but not without having to endure some side effects. I am really curious about the hair loss. I realize there are other things that can cause this but I'm reading that there are other people on glucophage that are also complaining of hair loss. My doctor said it is not listed as a side effect. Would love to know if it really does cause this! F 50 3 years
1/29/2008
 3  PCOS , Diabetes Type II Extreme thirst , stomach cramps , metallic taste. Alternating bouts of constipation and diarrhea. Sometimes so horrible either way I feel as if I'm literally dying. Headaches and tiredness. My glucose levels have been running pretty normal. Most times around 90-160 depending on if I am fasting or after I have eaten etc. Since being put on Metformin 5oo mgs 2x daily. I have had reoccuring bouts of painful constipation and extreme diarrhea. Extreme diarrhea meaning 6-8 times in a day. Of the "explosive" form at times. Most times leaving my rectum feeling as if someone has yanked my intestines out through it.. Yikes ! A lot of inconveniences , as I have to stay near a bathroom at all times. I have watched what I have eaten , and it doesn't really seem to matter most times. I know my husband was on it and he had the diarrhea frequently as well. BUT when he had those episodes his sugar levels were higher. Like around 200 and up. Mine I can have the diarrhea and my level is only 100. So it is unpredictable at best. F 36 41 days
1/15/2008
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 4  Type II Diabetes Minor cramping in hands (thinking it's elevated lactic acid). Gas city.... holy cow.... great way to clear out a house, but then again that could be my new ultra fiber rich diet, as well as eating just sugar substitutes like sugar-alcohols. Blood Glucose was in 300 range just one month ago. It's now in low 100 range. Combined with good diet, excersise, this drug 'buys' me 'headroom' at the dinner table. It's not a magic drug, rather it's an extract from the French Lilac weed. So, in a way it's a natural Sugar reducer. For a Type II that means it's a lifesaver. Sure there's some discomforts, but other than injecting insulin it's one of the few drugs to lower BG levels. It does not increase insulin production, rather it tells the liver to quit manufacturing glucose. M 51 30 days
1/9/2008
 3  diabetes Some cramping and loose stools the 1st and 2nd day. Then I felt fine. I got sick the following week and vomited so the doctor discontinued the meds. F 37 7 days
1/9/2008
 5  PCOS/infertility First 2 weeks, nausea, loose stool and extreme stools if you eat something the pills didn't like! I am taking 2000mg a day. I take a pill with each meal and then one before bed. I now do not have any issues with loose stools but I am much more regular then I ever have been. I have lost 10lbs, my energy levels are getting better every week and I'm very hopeful that I will be getting pregnant soon since my cycles are now to 33 days! F 30 3 months
1/3/2008
 4  PCOS/Insulin Resistant/pre-diabetic Nausea - to help decrease side effects, take AFTER a meal! If I do that, I don't have any side effects. My doctor slowly increased my dosage, which helped me deal with the side effects: I did 500mg 1x/day for 2 weeks, then 2x a day, I now up to 3x a day. I usually have nausea for a few days when I increase my dosage, but by the end of 2 weeks, I'm fine. I've lost almost ten pounds in the 6 weeks with NO diet changes on metformin/glucophage. My period hasn't come back yet, but I'm hoping that with continued weight loss, it will. F 38 6 weeks
12/30/2007
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 1  Type II diabetes Very bad - explosive - diarrhea and all the discomfort that goes with that. Dehydration as a result. Initial dosage was 2 x 500mg per day. Very angry that the doctor didn't mention the potential side effect. Information on the drug is confusing - it's considered very safe and widely prescribed, yet has bad side effects and is very hard on the liver and kidneys. M 51 4 days
12/26/2007
 2  PCOS nausea, severe thirst, very bad lower back pain(same as during period), haven't noticed any hair, weight, or period changes yet. I am usually, very laid back, but I have had severe bouts of moodiness since I started taking it over 3 weeks ago (may be unrelated). The constipation and stabbing lower abdominal pains are the worst! I also noticed a great increase in hunger. I hope these all get better soon. F 24 25 days
12/5/2007
 4  PCOS/trying to conceive Some headaches and diarrhea.Has eased tremendously since starting 5 months ago. I have been on Glucophage since June 1st. My period regulated to 35 day cycles.I added my first round of Clomid last month and I am now 6 weeks pregnant.My last post on this website was on 7/17/07. Again, if there are any questions,please feel free to email me. Good luck to all of you. F 34 5 months
11/20/2007
 3  Type 2 diabetes Switched from Metformin to Glucophage SR about three months ago because of diarrhea. All was OK for a while but now I experience severe bouts of explosive diarrhea and like one other post a lack of libido. Erections are not as they used to be and they can disappear quite rapidly. It is curious that this happens to coincide with taking Glucophage. All was well before I stared taking it. I will ask my doctor to change the medication to see if things improve. It is not just the fact that the erection is not strong any more -- the desire has waned also! Most upsetting. Please post or email if you too have noticed this. M 63 3 months
11/18/2007
 5  PCOS/Infertility diarrhea, upset stomach, gas, nausea and weight loss. Currently taking 1000mg per day after dinner and 150mg of Clomid. Not diabetic or insulin resistant, but I need to loose 20 lbs. So far I've dropped 3 lbs in the last few days. Too early to tell, but I hope this does the trick. F 30 7 days
11/14/2007
 4  Pcos, infertility When I first started taking Metformin 500mg it caused major GI tract issues for the first 2 days. As I have increased my dosage (now up to 1500mg per day) the GI issues have become much better. Just be careful about what you eat. Not too much food or too much fat. F 31 1 months
11/2/2007

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