GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  PCOS I have been taking Metformin for a total of two weeks now, and I have seen a lot of different side effects. I first noticed the diarrhea right after I ate. I have also noticed that I use the restroom more often than normal. Loss of appetite and definitely a metal taste in my mouth...Especially when drinking water. I have also gotten sick and vomitted a few times as well. Starting today, I will be doubling my dosage to 1000 MG a day. Overall, this seems to be a great drug. So far so good on Metformin. It's not very expensive for the 3 month supply, and it seems to be working!!!! So, that's always a plus. I have lost 10 lbs in 2 weeks, but I'm thinking that is due to me having diarrhea pretty much everyday...and getting sick a few times. I'm very curious to see how my body will react to another 500MG per day. I shall keep you posted. F 24 2 weeks
1000 MG 2X day
4/7/2010
 4  PCOS/IR/Weight Loss diarrhea 1st night only. dull headache some days. More energy, 10lbs lost so far. Will get numbers checked again in 2 weeks. F 30 2 weeks
500mg 1X day
3/17/2010
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 2  pcos Increased gas, soft stool, loss of appetite. I've taken glucophage before but do not recall the extreme fatigue I feel now. It's unbelievable! I have such low energy and almost feel depressed. Have been sleeping 10 to 12 hours each day since building up to 2 tablets per day. Am trying to make it to 3 per day but am struggling with the fatigue. May go down to 1 pill per day to see if this helps. F 36 21 days
500 3X day
3/17/2010
 5  PCOS Diarrhea, nausea, dizziness, decreased appetite Side effects only last about three weeks each time I started (twice now). This was prescribed by my OB/GYN to get pregnant, and it worked! My daughter is now 14 months old and we're back on the medication to get pregnant with baby #2. F 29 3 years
850mg 2X day
3/5/2010
 2  Type II Diabetes and elevated BS Did fairly well without problems when on 500 mgm twice a day, however my BS stayed high so my Endocrinologist increased it to 1000 twice a day. This caused stomach distress, diarrhea and nausea. As I am also on HIV meds I took a vacation from both but now have definately associated the symptoms with the increase in Glucophage. I will cut back to 500 and see if that improves things after speaking with the MD. That said, I am not sure that the benefits outweigh the side effects at this point as I am keeping the folks who make Pepto-Bismol in business M 64 5 months
1000 2X day
2/27/2010
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 5  Diabetes, Type 2 EARLY ONSET OF CRAZY DIARREAH WITHIN THE FIRST TWO WEEKS. NOW I AM CONSTIPATED MOST OF THE TIME. NO OTHER NOTABLE SYMPTOMS. I SEE SOME PEOPLE SAY THEY ARE NOT HUNGRY ALL THE TIME ANYMORE - I AM THE DIRECT OPPOSITE, ALL I WANT TO DO IS EAT! MY BLOOD SUGARS ARE TEXTBOOK AND FOR THAT I CAN'T COMPLAIN! I DROPPED 12LBS WITHIN THE FIRST 2 WEEKS, THE LAST 4 WEEKS I HAVE GAINED BACK 3 LBS OF IT AND NOT LOST ANYMORE WEIGHT. IN FACT I AM NOTICING THAT I AM ALWAYS HUGNRY NOW. I HAVE NO OTHER SYMPTOMS AND FEEL OKAY, NOT MUCH DIFFERENT FROM BEFORE. I NOTICED IT AFFECTED ME MUCH MORE IN THE FIRST FEW WEEKS NOW I DON'T EVEN NOTICE I AM ON IT. I'D LIKE TO GO BACK TO LOSING WEIGHT! DOCTOR WANTS ME ON IT FOR 6 MONTHS THEN I GO BACK FOR FOLLOW UP BECAUSE MY NUMBERS HAVE BEEN SO GOOD. F 31 6 weeks
500mg 2X day
2/18/2010
 4  PCOS When I took 2 500mg tablets per day, I had constant anxiety -- that feeling in the pit of your stomach when something bad is about to happen. Not a listed side effect, but absolutely linked to Metformin for me. Mild stomach upset when I first started taking it, but none now. I dropped down to 1 tablet/day and the anxiety went away. F 34 8 months
500 1X day
2/17/2010
 5   Softer bowels at times. Nothing inconvenient. I consider Glucophage a miracle drug. It lowers the glucose level, reduces appetite, allows you to lose pounds rapidly. I highly recommend it. F 49
1X day
2/13/2010
 2  PCOS/Weight Loss Stomach pains, gas and extreme mood swings. I would not recommend this for anyone looking to help PCOS, the side effects are not worth it. F 27 6 months
500mg 1X day
2/7/2010
 4  pcos gas, loose stools, tingling in legs at night Taking it for pcos and excess testosterone. I've been on it ten days. First few days caused embarrassing gas/diarrhea that led to 2 accidents. All i'm saying is: resist the urge to fart until you can get to a toilet!! Then I realized you have to take it right after a meal not before, and avoid dairy. No new acne yet..this is the most wonderful news..i'm keeping my fingers crossed that it stays this way as nothing else has worked for me..my chin hair growth has slowed noticably in the last couple days...also i have lost about 2 lbs:)...oh and my cycle-related breast pain/swelling-which has been getting worse lately totally went away after four days on this drug. also i noticed a return of vaginal moisture and secretions almost immediately, (i used to be dry all of the time.) i did start my period 4 days early today. i am used to it only being 3 days long but i hope it returns to 5-7 days. the last side effect i wanted to mention is at night my legs feel tingly, like they are floating, and then i end up jerking them to get rid of the sensation. not sure what thats about, but i think i remember from nursing school that it indicates an electrolyte problem. not on any other meds but multi vitamins. F 30 10 days
500mg qd 1X day
2/6/2010
 3  TYPE 2 DIABETES DIARREAH, BUT NOT AS BAD AS MOST DESCRIBE.."GURGLY STOMACH" GAS, I FEEL TIRED AND HUNGRY.. BUT NOT SURE IF IT IS RELATED SINCE IT IS STILL VERY EARLY ON THE MEDS I'VE ONLY BEEN TAKING IT FOR 2 DAYS, BUT MY BLOOD SUGARS ARE STILL VERY HIGH. I HAVE HAD BOUTS OF A "GURGLY" STOMACH, BUT MOSTLY FLATULANCE AND DIARREAH COMES ABOUT 5 HOURS AFTER TAKING THE PILL. I'M ON 500MG 2X A DAY. ANYONE KNOW HOW LONG IT TAKES TO SEE BENEFITS? F 31 2 days
1/25/2010
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 4  Insulin Resistance & PCOS somewhat loose bowels, weight loss, decreased appetite I've struggled with PCOS for years and was recently diagnosed with Insulin Resistance. Started taking Metformin 4 days ago and have lost 5 pounds. I've had somewhat loose bowels, but no diarrhea. I've struggled to eat over 1000 calories in a day. I've lost all cravings for sweets and carbs :) F 28 4 days
1/23/2010
 5  PCOS and Insulin Resistance Metallic taste in mouth and mild nausea when taking with an empty stomach. I first started taking this medication when I was 16. I weighed in at 170lbs. The first week was icky but not unbearable. I had no bowel symptoms just a metallic taste and nausea when I took it on an empty stomach. Six months later on a low-carb diet (Allowing a Saturday splurge - though most cravings had vanished) and a 30minute work out once a week I was down to 125. Being a foolish teenager and considering myself cured I went off the medication only to regain the weight and fall into the same slump I had been at 16. 8 years later I'm back on the medication and aside from the metallic taste (Which I know will go away in about a week.) I'm feeling fabulous but mourning the fact I no longer care for chocolate! F 24 2 weeks
1/20/2010
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 3  High Sugar/Pre-Diabetes I have experienced Diarrhea.on a fairly regular basis. http://diabetes.webmd.com/tc/prediabetes-medications [We MD] is a good reference. Obiously, we all know that diet and exercise is a critical component of controlling diabetes. Be your own advocate, do research about any medication, and then ask your doctor. Wikipedia at http://en.wikipedia.org/wiki/Metformin is a good quick reference. The Diabetes Self-Management site at http://www.diabetesselfmanagement.com/Blog/Amy-Campbell/metformin_and_risk_for_vitamin_b12_deficiency/ notes that Metformin may cause a vitamin B12 deficiency and to ask your doctor if this is the case with you. Side effects of B12 deficiency are numbness, pain, or tingling in your hands or feet. Metformin/Glucophage may cause kidney problems, so I also take Dandelion. Web MD also has a homeopathic article on Milk Thistle, but use caution if you also opt for this additional homeopathic option: "Some herbal/diet supplement products have been found to F 54 1 years
1/14/2010
 2  Diabetes type 2 General 'not well' feeling, abdominal pains, intense hunger, nasty bowel movements I take 500 mg twice daily. It has lowered my blood sugar about 40 or so points, but the side effects are quite bothersome. I suspect my Doctor will want to increase it the next time I see her and am anticipating that the side effects will be even worse. Thay have not decreased since I began taking it. M 52 2 months
1/13/2010
 5  PCOS diarrhea for the first two weeks that now is gone. tiredness that also went away. I lost 13 lbs on this drug without effort (from 127 to 114), my sugar cravings and binges simply went away. I still eat some candy, but I eat a couple pieces and that's enough where as before, since I was insulin resistent, I was craving sugar non stop. I also now have much more regular periods which is a blessing. I also see a decrease in my acne (actually don't need creams any more). This drug literally changed my life. F 29 6 months
1/11/2010
 4  PCOS I have been on this med once before and couldnt handle the diaherrea. Now back on started at 250m now up to 1500m a day. Had some diahrrea the first few weeks with nausea and stomache pain but now am doing better. Me and my Husband decided to do this to try for baby #2. I finally got my period after several months without. Now I am 10d post period and am having light spotting. Does anyone know what this could be from? I have never had this problem and am a little nervous. F 25 4 weeks
1/9/2010
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 3  PCOS/ Infertility I'm taking Glucophage 1500mg XR. I had diarrhea the first day, and now I alternate b/t loose stool and constipation depending on what I eat. It's not too bad. I gradually increased my dosage and I think this helped minimize my symptoms. BUT I've always had very regular periods and now my period is late (only 4 days, but strange for a drug that's supposed to "regulate" periods.) Has anyone had a similar experience??? My RE put me on this medication because my blood work came back with abnormal hormonal levels suggesting PCOS...and a vaginal ultrasound confirmed multiple cysts in my left ovary only. I have NO OTHER SYMPTOMS of PCOS. I've always had regular periods, I ovulate regularly, I am underweight if anything, I don't have acne, and don't have hirsutism. I still have a hard time believing I really have PCOS, but after 4 years ttc I am willing to try anything. Additionally, despite always having regular 28-day cycles, my first month on Glucophage I am 4 days late for my period. What gives? Has anyone had a similar experience??? F 30 30 days
1/7/2010
Email
 4  type II diabetes M 76 10 years
1/4/2010
 4  High Insulin Initially diarrhea for the first 2 days, but nothing else since then. I was really scared after reading some of the posts but I finally tried it and was very surprised that my body got used to it so quickly. My insulin is now in normal levels and I have also lost weight along with a low fat/good carb diet. I do not crave sweets, pasta, breads, etc. AMAZING! M 51 2 months
1/2/2010

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