GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  PCOS I haven't started taking it yet, but I'm reading all the other reviews and I'm really scared about the side effects. Sorry this isn't a review, but a question - I'm hoping someone will know the answer... I know that you are not supposed to take this medicine and drink alcohol. I don't drink often, but there will be occasional nights here and there where I'd really like to drink at parties or bars with friends. Do you recommend just skipping the dose of the medicine for that day, or is there a better solution to get around this? I'm scared of that acid reaction! I'll check back often for any responses, or please shoot me an email! Your response is much appreciated. F 22 0 days
6/27/2008
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 5  Type 2 Diabetes No Side Effects I have been on 500mg Extended Release (Eon Labs)for about 45 days now. I was afraid to take the medication after reading about the side effects listed on this forum. I decided to stay home for a couple of days when I started taking the meds, just to be sure I didn't have explosive diarrhea like so many others had. I was pleasantly surprised when nothing happened. I haven't lost any weight, but I haven't been glued to the toilet either. My blood sugar levels are now doing fine. M 53 45 days
6/25/2008
 4  Insulin Resistance + suspected PCOS Until I switched after 3 months from regular to TIME RELEASE, I had very bad stomach pains, fatigue, and general weakness unless I was ridiculously careful about eating (like a bite of fruit every 10 minutes). Once I was on the time release, I then experienced the same symptoms from time to time along with what I eventually associated as hunger. I've been on it 10 years and I'm thinking about getting off. My hair follicles have become finer and less dense, though only noticeable to me. I have trouble keeping weight off without the pills, but on days I forget to take them, I feel like a million bucks. I'm sure it's the best RX for me and my condition, but I want to try treating it without the medicine as I think my liver and kidneys are paying for it. I just don't feel right. F 24 10 years
6/23/2008
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 3  Type II Diabetes Diarrhea, nausea for the first two weeks, taking 1000 mg of Metfromin twice daily. Also lethargy, although that may have been due to changing to a low-carb diet. Six weeks into it,am having diarrhea 1 or 2 times a week. BG is running 150 to 200, but I would like to do better. Have lost 9 lbs eating low carb. Energy a little better. F 46 45 days
6/19/2008
 4  Type 2 Diabetes I had no side effects at first. However I have been on this for one year now and am starting to have bad bloating, gas, and nausea. I have lost 40 pounds and all blood tests coming back are really good now. F 33 1 years
6/18/2008
 3  Type 2 Diabetes I am taking Metformin 500mgx2. I started 8/29/06 and started having daily diarrhea especially in the morning. I did not suspect Metformin in the beginning and the doctor did not mention this side-effect even when I complained about it. The blood sugar is fine I eliminated some medications but not the Metformin and the diarrhea got worse and worse. Finally I read this blog and found out that other people have the same symptoms. I was also taking the blood thinner Plavix. Yesterday I got a serious scare when during one of my bouts with diarrhea I found blood in the stool. I stopped the Plavix. I stopped the Metformin as of 6/17/08 (today) and will watch my blood sugar for this period. I will notify my doctor. Today has been the first day off Metformin. I will see what happens. M 68 45 months
6/17/2008
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 4  PCOS Taking 850mg twice a day. Brief but FIERCE nausea and diarrhea. I frequently went from feeling just fine to wanting to lie in bed or over the toilet and just cry. After two days, it became much better, but I am still having nausea/diarrhea if I overeat or eat too much fat. This page has helped me so much that I just had to leave a comment. I hope to add updates as time goes one. I've had PCOS since I was 13, and have taken Metformin since then. However, because I'm stubborn or just don't like to admit I have a condition, I always stop after a few years. Well, this time I stopped and gained 40 pounds, so now I'm back for another round. So far, so good. Some horrible nausea and diarrhea, but my appetite is back under control and I've lost weight already. Plus I have more energy to get through the day. F 25 7 days
6/10/2008
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 3  PCOS-Insulin Resistance My hair fell out! I recently spoke with my doctor and he claims that hair loss is not a side effect for this medicine. I was stressed and I did put permanent color in my hair. But it was a drastic loss of hair and I have just been prescribed the extended release, yet I am still scared to take it as my hair still hasn't grown back. However, I did start this past weekend and thus far a lil stomach irritability is all. Major weight loss. I lost 11 pounds. However, due to the weight loss I used the medicine on a very inconsistent basis. As a result, when I stopped taking it the weight came right back. F 24 1 years
5/5/2008
 2  105 fasting glucose stomach rumblings and gas Doctor thought that I should take this drug to lower fasting glucose -- I didn't think the number warranted drugs but some doctors are more cautious than others -- I've limited sugar consumption -- haven't lost weight -- suspect it's allr related to menopause F 51 30 days
5/3/2008
 4  insolin resistence nosia, headache for the first week only. Great medicine, helped me loose weight as well F 31 40 days
5/2/2008
 2  Rule Out Metabloic Syndrome, fatigue, muscle weakness, diarreah, flu like feeling of weakness. My doctor suspected insulin resistence but blood work was negative. She suggested this could be very early Metabloic Syndrome because of weight gain, and being so tired despite my work out level. We tried the Glucophage. Started at 500 mg with the goal of titraing up to 1500mg. I has some diarrheh at the lower dose but by the time I got to 1000mg I felt like I had been run over by a truck. I could not even get up out of bed. At first I thought i had the flu but it was after 2 weeks of this my husband suggested it was the drug. I stopped the medicine and the next day felt better. I did give it a second try under doctors advice and again could not tolerate it at all. I hope I never develop Type II diabetes and have to take the drug but for now will just try changing my diet and workouts. I feel sorry for any of you that have to take this medication for diabetes. F 44 2 months
4/19/2008
 4  Type 2 Diabetes haven't noticed any negatives I've used brand Glucophage and generics by Ivax, Teva, Andrx, Zydus. I've found that the generic by Zydus available at CVS works better than the Glucophage brand. VERY noticeable decrease in BG over Glucophage. There IS a difference between generics, if you're having a side effect, change to another generic. Ask your MD to write a scrip for Zydus brand and pharmacy must order it. I've had this with other drugs as well. M 49 2.5 years
4/14/2008
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 4  PCOS, insulin resistance At first - Hunger, nausea and dizziness if I didn't get enough cals or at the right time. Stopped after a month, tried balancing progesterone and thyroid. Once they were in balance, I still couldn't lose weight. Now at 500 - 1000 a day, for the last three weeks, I have lost 14 pounds. After only gaining for the last 8 years, I am VERY HAPPY. I now have more energy and plan to ease into more excercise. I am glad I gave it another chance. I do feel more energetic- even a little wired at times. After having been nearly comatose at the end of a workday, this is a blessing. F 35 25 days
4/9/2008
 3  Elevated insulin level...maybe PCOS i havent started the medication yet hey everyone, i am going to be starting glucophage soon, and i am really nervous about it, so do any of you have any advice for me? like how to reduce the diahreah and constipation and just general nausea?? if you could let me know, that would be great F 18
4/9/2008
 5  Insulin resistence slight abd problems in the beginning, head aches as well. I have been taking this for almost three months now. 500mg before bed, may it's not enough I am still starving to death and feel like I need to eat more and finis my meals with something sweet. I have gained 25lbs in the last 6 months and can't stop eating.....I think I might add cinnamon pills. F 29 3 months
4/7/2008
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 4  type 2 diabetes First three weeks had horrible cramping, gi problems, headaches, overall nausea....dosage was increased gradually, but it didn't really help. Felt horrible for those three weeks. Has definitely helped with blood sugar levels.....if you can make it through the initial side effects F 35 4 months
4/7/2008
 4  Insulin resistance/rising BG My mother and grandmother died of complications from Diabetes. When I was 40, I suddenly started gaining lots of weight -- over 100 pounds in 5 years -- all docs said "to lose weight" and that I was insulin resistant. I am now 57. Been holding off diabetes just barely as my BG has been climbing. I read about metformin and asked my GP to put me on it. Only taken for 12 days. 500 am; 500 pm. Sides are same as others -- lots of diarrhea. BG has gone from 120-130 in am to LESS THAN 110 already. No weight loss as yet, but I sure hope that this helps as I eat very well -- low carb, small portions -- but have not been able to lose weight in 20 years unless I do a complete fast. Primary thing, however, is to prevent diabetes, and I will be very happy if this does so and hopefully the side effects will lessen. F 57 12 days
4/6/2008
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 5  
4/1/2008
 4  Type II diabetes For the first time on this page I could compare my experiences with those of other patients. I was a bit nauseous in the beginning, but that passed. What does bother me is that the intestinal effects are unpredictable and range from diarrhea to constipation -- and don't take a magnesium supplement at night with your pill!! Oh boy ... you're off to the bathroom 3, 4 times from about 3am. Explosive. Not nice at all. I also seem to tire far too quickly and I am often sleepy -- side-effects? It would seem so after reading other comments here! I take 1000 mg twice a day, with meals. I put myself on a high-protein diet and I certainly don't do low-fat anything. My diet is a bit of a problem during the day -- one gets an awful desire for carbs. But my A1C test after 3 months was 5.4%. (It was 6.8% when diagnosed) It does work. But I also take AntaGolin (a South African product, not medicine, helps with insulin levels) as well as cinnamon capsules. I am, however, VERY WORRIED about the hair loss complaints. I have the impression I'm losing too much hair and wondered why. My hair is baby soft and thin -- can't afford to lose hair! I'd like to cut down on the Glucophage but I don't want to mess up my blood glucose. I've lost 10 kg (about 22 lbs) in less than 3 months and although I'm pleased with that, I can hardly afford to lose more. Yet I don't have much of an appetite. I should add that I do drink wine with dinner, and my pills get swallowed with wine!! Wine seems to help my numbers. F 66 2 months
3/25/2008
 3  diabetes type 2 slight headaches, tired, no GI effects though Can someone tell me how long this drug takes to consistantly lower blood sugar?? Mine is fluctuaing and my doc said after a week I would notice numbers coming down, but they are still mainly above 200. The only time my BG numbers go to near normal is right after I excersise, so not sure if it's the glucophage working or if it's just the exercise. I am taking 500mg twice daily and wondering if I need an increase the dose M 34 14 days
3/17/2008

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