GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Type 2 Diabetes nausea and EXTREME diarrhea Started 250 mg 1 x per day, then 2 x per day, then 3 x per day, then 4 x per day. Changed each dose every two weeks. Diarrhea has never stopped. Seems to be worse if I eat light and healthy. After 1-1/2 years, I dropped my own dose to 2 x per day 3 months ago. Diarrhea improved somewhat. Went on healthy eating program again...EXTREME diarrhea started up again. I'm going to stop taking it. I've told my doctor many times that it's unbearable, but she keeps saying to hang in with it. I'm done. Glucose levels did drop. (Still over 7.0, though.) Energy level improved. Experienced weight loss of about 15 lbs. F 47 1.5 years
9/22/2006
 4  Slight PCOS Nasua, slight stomch pains, decreased appetite i have been taking metformin for about 2 1/2 weeks now starting on 500 mg and have now worked up to 1500 mg/day. I hoped to loose some weight on this pill, but I have not lost any yet...is there still a possibility of weight loss? F 22 17 days
9/18/2006
 5  type II cramping, gas, diarrhea - these were frequent at first, but increased dose gradually and now only have cramping & diarrhea once very week or two. Lost of appetite, weight loss, metallic taste in mouth - very common to start but now very manageable the lower blood sugar is definitely worth the side-effects. M 49 2 years
9/17/2006
 3  Pre-Diabetes I have only taken 2 doses so far, but I am already having serious spontaneous runs. I feel a little edgy and my heart seems to be pounding. My energy seems better though. Not so draggy. Also, metallic taste in mouth. Water retention seems to be less severe. My stomach so far hasn't felt nauteous, but I feel like I'm on speed. Recently diagnosed with diabetes. I suspect I have been pre-diabetic for a couple of years, but nobody thought to test me. I have had a sudden dry skin/rash spell that has lasted over a year and nobody thought to test me for diabetes (apparently that is one of the first physical symptoms of the disease). Feel free to email me. I would enjoy hearing from others taking this drug. M 41 2 days
9/15/2006
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 2  
9/8/2006
 5  UPDATE weight loss & tons of energy This was a update to my earlier post. I went to the dr the other day and I hadnt said a word to them about my weight loss and outa curisty asked them my weight from when I was there last lol. Their last weight was 256 or so. Now Im down to 213 Ü Yehhh. She kinda did a double take and said wow uve lost alot of weight lol... Nice to go to the dr for the first time and not be gripped at about not losing or gaining more. F 28 2.5 months
9/7/2006
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 5  pre-diabetes - weight lose Stomach cramps the first day and frequent trips to the restroom - no time to question if you need to go -YOU GO!!! Ramping up to 1000 mg twice daily (1)morning (1)night My dosage seems higher than other ratings. I hope this works. Unsure how I feel at this point - still lack energy - but alot of weight to loose. Current weight 270 goal 180. Wish me luck F 39 1 weeks
9/4/2006
 3  insulin resistance/PCOS OMG, nausea and some frequency in bowel movements (sorry), reduced appetite, weight loss. WEIGHT LOSS - woohoo After visiting an endocrinologist who did every test under the sun except for PCOS despite having 6 out of 7 presentations including central obesity and gestational diabetes, my GP put me on glocphage. I like it, apart from the nausea. I lost about 7 pounds in two weeks, my appetite is reduced and I have made lifestyle changes but my main area of treatment is insulin resistance and pre-diabetes cos my Dad is diabetic and I have high cholesterol treated with lipitor and I also take xenical for weight loss and it works. The nausea was averted by taking my metformin in the middle of my meal, so I am good to go. I am scared to gain the weight once off the metformin whioch might be recommende3d when my hormones regularise. Hmmmm F 42 2 weeks
8/15/2006
 4  PCOS I experienced diarrea for the first couple of months,nausea every night,just an all over sick feeling I lost about 15lb. the first month, I've lost 5 more pounds since then, I've started exercising more to see if I can lose any more weight. The good thing is that I've kept the weight off, before metformin I would have gained it back right away. I do not notice any difference w/ facial hair. May have get on another medication to stop the facial hair growth. The sick feeling still continues mainly at night, but it is not as often as it was when I first started. Was getting major lower stomach pains before starting the med. 2wks after my period ended. Thought this med. would help, but I still get the pains. If anybody has any opinions on the pains, please email me. I don't know what to do about them, I have to take vicodin for them, and don't want to become dependant on it. I have talked to my doctor, she told me to just stick w/ the med. that it may take awhile for the pcos symptoms to go away. F 25 5 days
8/9/2006
 3  PCOS/Infertility I have experienced very little side effects, slightly less appetite I concieved last January and miscarried at 11 weeks. OB then put me on clomid for two months and it did not work. Then was refered to a fertility specialist that diagnosed me with PCOS after doing an ultrasound that showed my ovaries were full of cysts. I started taking glucophage 4 weeks ago and I am hoping this regulates my periods and then in turn allows my body to ovulate. I go back to the fertility doctor on Aug. 8th to talk about ovulation induction possibilites. Feel free to email me if you have been through a similar situation. F 30 4 weeks
8/3/2006
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 2  PCOS Severe tiredness, bloating, constipation Started taking 500mg 1x/day SLOW RELEASE version and had minimal side affects. After two weeks moved up to 500 mg 2x/day and just started tiredness and constipation. Hoping it will regulate cycle (went 120 days without period this year) so we can get pg...am concerned it won't work since I haven't had a period in the month I've been on it. Any thoughts??? F 30 4 weeks
8/2/2006
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 5  P.C.O Dont wait to go to the bathroom.... Or youll be washing some clothes next lol Amazing pill. After a few days I started noticing I had energy to do everything I wanted Plus more. I have lost about 33 lbs in 1 and a half months. (I have a hard time remembering to take pills, when I do stay on track the weight is flying off) My periods are almost clock work again. Hair on my face I still havnt really noticed a change yet, but the hair on my legs has slowed down to nothing now. My complextion is clearing up amazling to. (acne) Glucophage is the only current meds I am taking for P.C.O. F 28 1.5 months
7/28/2006
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 3  To loose weight Diarrhea, naseau, not to much but when it happens it's bad Ive been taking it for 2 weeks and ive lost 3 pounds, not what i hoped for but i'll keep taking it and see F 24 2 weeks
7/16/2006
 3  To loose weight/ insulin resistant Diarrhea, naseau, not to much but when it happens it's bad Ive been taking it for 2 weeks and ive lost 3 pounds, not what i hoped for but i'll keep taking it and see F 24 2 weeks
7/16/2006
 3  Type II Gas (belching and flatulence) for the first couple of weeks My doctor put me on this to lower my sugars and help with weight loss. I haven't seen either of these happen. But, when I stopped taking the medicine for 3 weeks (I ran out), my sugar was a bit higher than it normally is. I don't have the side effects that many talk about, but that could be the low dosd I'm taking at 500mg/day. It did not decrease my appetite. In fact, I think it increased it for a time. Interestingly, it did regulate my menstrual cycle. F 40 3 months
7/12/2006
 2  Insulin resistance Severely swollen ankles that felt like they were going to burst. Burning feeling on the soles of the feet. I had to stop taking this after five days--the symptoms were that bad. F 44 5 days
7/12/2006
 5  pre-diabetes, lack of energy maybe some nausea at first.. still experience frequent constipation & the drug totally changed my bowel habits (sorry..eww) I'm using Metformin 500 (twice/day) in combination with Wellbutrin XL 300 (anti-depressant), and now I have much more energy, lost 15 pounds without changing food habits, now I've lost a total of 36 pounds with the drugs & food plan. I have more motivation, and I don't feel like I have to eat all day. Before Metformin, I'd graze on snacks because I felt tired all of the time.. not anymore! No more lazy couch potato days! F 27 1.5 times
7/9/2006
 5  pre-diabetes, lack of energy sorry.. I posted the previous comment.. I meant to put I've been taking Metformin 1.5 YEARS. F 27 1.5 years
7/9/2006
 5  pcos definitely had upset stomach/diarrhea for the first two weeks, plus no appetite the first time i started taking glucophage i lost 29 pounds, which was a miracle, usually im like a compulsive eater but it made me have no appetite to the point that i COULDNT eat, i stopped taking it in college cause i couldnt drink on it and have gained atleast the thirty pounds back, i have no been on it again for a week and all the side effects are the same (so i hope the weight comes off again too!) F 22 1 weeks
7/6/2006
 3  pcos-IR i have only had it for 3 days and my mouth tastes bad and loss of energy i am on 500mg a day- mild stomach upset, i dont know what the next few days will bring F 33 3 days
7/6/2006
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