GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  PCOS Occasional cramping and diarrhea, mostly after eating fatty foods. Decrease in appetite. A few episodes of mild heartburn. I was very nervous to start this drug because of all the side effects I had read about. I'm terrified of vomiting (emetophobic) so the fear of side effects was quite strong. Overall, though, it's not too bad, and I'm relieved. The cramping and diarrhea can be inconvenient, and there have been a couple of times that I've stayed home or come home early to be in my own bathroom. One great thing is that I find that I'm not craving chocolate anymore, and don't really feel like snacking. My advice? Don't be scared by others' side effects, and give it a try. F 32 16 days
250mg 2X day
12/22/2010
 5  PCOS stomache cramps and diarrhea after that, loose stools, tiredness so I take it at night As soon as I started taking it, my period that had gone on for 60 days just stopped. My energy level has improved significantly in the past 2 weeks, and my mood has been elevated a lot. I feel like this drug is going to change my life for the better. No weight loss, but I have the energy to get to the gym and really feel I can do things of my own volition now! F 22 14 days
500mg 1X day
12/14/2010
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 4  pre-diabetic Constipation. Condition did not change with XR. Interestingly, when it was taken in the night (before sleeping) instead of morning with breakfast - no side effects, no constipation! Go figure. M 52 4 years
500 Mg 1X day
12/6/2010
 5  PCOS and insulin resistance I have occasional headaches and stomaches. Most days I have explosive diarrhea but other days it is regular. The smell is awful. I have very painful cramps before the explosive kind. I have to stop what I am doing because of the pain. I have lost more than 50 pounds while on this medication. I have less body hair and I have a lot more energy. I had a loss of appetite. It also regulated my periods. The pain was worth it, I feel great! F 21 2.5 years
750 2X day
12/1/2010
 5  PCOS/Insulin Resistant First night mild cramping, soft stools and nausea I have already notice an increase in my energy level. Thanks metformin, i'm so excited about our future relationship together.. lol.. im hoping to get pregnant in the near future, no rush but i am so happy because there is "HOPE" thats what i have been praying for. F 28
500mg 2X day
11/18/2010
 4  PCOS I literally had no side effect;just that I got extreme hunger pangs for the first two days and a bit of nausea. The side effects lasted for just 2-3 days after I started the medicine. I lost 2 kilos in one month without working out at all. My ovary size (which were bulky otherwise)went down drastically in this one month too. M 29 1.5 months
500mg 3X day
11/13/2010
 4  PCOS slight nausea at times and some diarrhea (once a week at most), 5-10 lbs weight loss I have been taking metformin for 6 months now to try to treat PCOS as my first attempt at treating infertility. Although this medication did not help regulate my cycle, I don't mind being on it. I feel as though it has regulated my blood sugar, I have lost a few pounds without trying (always good, right?) and the side effects have been fairly sporadic and minimal. If only it had worked to treat my PCOS! F 33 6 months
500 MG 3X day
10/22/2010
 3  Dr. prescribed it for Type 11 Diab. SWOLLEN BELLY AND CAN'T SMELL OR TASTE F 75 10 days
1000 2X day
10/20/2010
 3  PCOS loose stool it seems just on the days I up the dose then I am firne, some stomach discomfort at times. Started takeing Met about 2 months ago for PCOS. I started out with the 500xr and got up to 1500xr a day.I had no side effects at theat time. I did some research and found Met good for weightloss too! I asked my doc to take me off the XR as I read it's less effective for the weightloss part and put me on the regular. She did, now I am taking 1000 in the morning and 1000 at night but I have had no decrease in appitite at all. I only have stomach problems on the day I up the dose then I am fine. Right now I am trying to play with the dosages and take them at different times to see if that helps. Anyone have any insight on the appitite decrease? F 38 2 months
1000 2X day
10/10/2010
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 4  Insulin Resistant/Weight Loss Constipation, gas, bloating, upset stomach, loose stools I started this medication slowly with 500mg for 1 month then moved to 1000mg for 2 months. During this time I have experience slight appetite decrease and actually had some constipation. With my follow up Dr appt she has increased my dosage from 1000mg to 2000mg. I have only been taking this for 2 days now but have experienced looser stools but only in the morning so it doesn't affect my daily routines. F 34 3 months
2000 mg 1X day
9/29/2010
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 4  PCOS Gurgling stomach, loose digestion, fatigue, and decreased appetite. It is a relief to have a medicine that helps fertility that does not make you gain weight! I have been on metformin leading into assisted conception and first trimester of a successful pregnancy. I am back on now for pcos hoping for another successful pregnancy. I am happy to take the bad with the good that comes from this medicine. F 40 7 months
850mg 2X day
9/28/2010
 4  PCOS + Diabetess type 2 occasional loose stool, tiredness, headache (bad) Yesterday my sugar level was 125 in the evening (past reading 235+)- YAYYYY!!! It definitely takes time to work. With diet you can control diarrhea/constipation. I have really bad headaches on the top of my head :-( Any ideas what to avoid or help with that? I will start writing down what I eat because not every day is bad... Hoping for a baby next year! F 31 8 days
500 2X day
9/21/2010
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 5  insulin resistance/to help wt loss none lasting. started slowly at MD suggestion, 500 mg then up to 1000 in one week My NP offered this to me to aid weight loss. I had excellent results - 296 to 215 in about 10 months and have kept it off. I was aware going in that I would only lose about 60% of what I needed to lose to be of normal weight, but was willing to give anything a try. I watched my portion size and carbs, but essentially the weight fell off. F 55 2 years
1000mg 1X day
9/4/2010
 1  type 2 diabetes @500MG had some stomach pains and diarreah.@1000MG had severe fatigue and chest pain.I had pains in my stomach with diarreah.left side of chest had numb deep pain. Kept explaining this to my doctor he was no help for months.I just finally told him I refuse to take it any more.I was so sick I thought I had cancer or something.I kept working and was in so much pain I thought I would have to quit my job because of the physical pain I was in. M 39 4 months
500 mg 2X day
9/3/2010
 3  Insulin Resistance/Weight Gain Loss of Appetite (initially), nausea, tiredness, acne worsened, bloating 2 hour insulin test was high, although blood glucose was normal. I'm in that peri-menopausal phase and had weight gain around the middle that I could not lose, despite strict diet & exercise. Diagnosed as insulin resistant. Started on 500mg and went to 1,000mg after two weeks. Then tried 1,500mg but could not tolerate. Initially lost eight pounds, but plateaued after that. It made my irregular periods very regular, but unfortunately, made my acne alot worse. Med makes me feel very bloated with alot of water weight gain. Tired all the time, even though I take Vitamin B Complex/B12. I take generic and pills smell disgustingly fishy...yuck! I am slowly discovering this med may not be for me in the long run. F 41 5 months
500 mg 2X day
8/27/2010
 3  PCOS NONE JUST SLEEPINESS I WAS HOPING TO LOSE A FEW POUNDS ON THIS MED, SO FAR ITS BEEN ONE DAY I TOOK 1500 MG, AND NO SIDE EFFECTS. DOES THIS MEAN ITS NOT WORKING?? :/ F 25 1 days
500 MG 3X day
8/19/2010
 1  Weight loss to counteract gain Constant liquid diarrhea. Horrible stomach cramps. Sometimes if I eat a banana it helps, but not every time. Can't go anywhere unless it has bathroom. It has limited my life and my families lives incredibly. I would NEVER recommend this to anyone! F 36 1 months
500mg 2X day
8/14/2010
 3  PCOS, insulin resist, cycle regulat severe diarrhea, metallic/bloody taste (esp.after water), EXTREME breast tenderness, cycle went from 35-37 days-first month, no change in weight-less hungry but less activity & EXTREME fatigue, sore muscles-esp. ankles & shoulders, all pre-diabetic symptoms/numbing hands & sweet cravings gone, some anxiety, nausea & heartburn at night, headaches first thing in morning and at night, dizzy when i work out or increase activity. started taking metformin to regulate periods, stop cyst growth, maintain pregnancy & regulate cycles after 2 miscarriages. all the doctors told me that my loss of feeling in my hands was due to carpal tunnel syndrome that developed during last pregnancy. it never went away and despite a history of diabetes in family, they would not test for it. i was always fit until after the pregnancies, then i gained A LOT of weight (80lbs in less than a year) and cant lose the weight no matter what. after taking metformin 1 week, the diabetic symptoms were gone. my cycle has gone from erratic/long to 27 days in the first month, im nauseous & have heartburn at night, and the diarrhea never seems to go away. very sore muscles in morning and night and im TIRED ALL THE TIME! F 39 1 months
1000mg 1X day
8/3/2010
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Patient History
 3  metformin nausea, mild headaches, loose/soft stools, dry mouth and loss of appitite I was diagnosed with PCOS and have gained weight in my belly. My periods come when they feel like it and my husband and I have been unable to concieve since our last child 6yrs ago. I started out taking this drug once a week for a week and just started twice a day. I had nausea and loose stools and still do but not as bad. I can't speak on the area of helping regulate my cycles yet but I have lost 5lbs since taking and hoping to loose more as well as concieve more children. F 24 2 weeks
500 2X day
7/27/2010
 3  PCOS Sleepy so I usually take it at night. In the beginning abdominal pain. Headache if I take it during the day. I'm taking this to regulate my cycle from PCOS. Not diabetic and no other health problems. I don't really belive I have PCOS because I only have had two cysts and they were large, not small and many like PCOS sufferers. That being said my cycles are way off and I keep gaining weight in my stomach. I haven't lost any weight so far but it does help with hunger. F 31 3 weeks
500 1X day
7/21/2010

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