GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  infertility extremely thirsty all the time, light-headed if I don't snack throughout the day I've been taking this at 1000mg a month for 10 months after 2 years of trying to conceive. So far, not pregnant. Metformin has regulated the length of my cycles to 32 days rather than ranging from 28-35. That's the best I can say for it. F 33 10 months
8/9/2007
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 3  Type II diabetes explosive watery diarrhea many times a day I have taken this drug for 2 years, although when it was titrated to 500 mgs 2x a day (AM and PM), I get diarrhea about 2-3 hours after taking it in the morning and have about 3-6 bouts of diarrhea the rest of the day. And then I get it in the AM once I get up, about 1x. A lot of times I don't take it in the morning if I have somewhere to go that afternoon and can't readily get to a bathroom. I have, however, lost 20 lbs, and am still losing. My doc said she would change the med, but I like the weight loss and will hang in there as long as I can. As for the diabetes, I am not very compliant, but my A1-C has been relatively near normal. F 56 2 years
8/7/2007
 4  PCOS / Trying To Conceive Diarrhea / Very Minor Dizziness On Occasion / More Energy Each Day I'm On It I currently taking 500mg twice a day, both with a meal (one around lunchtime and a second about six hours later with the evening meal). I only have a loose bowel or maybe one bout of diarrhea if I eat higher carb foods....but if I eat anything greasy (even two thin slices of pepperoni), I get the sudden bouts of diarrhea. I think there is a definite correspondence with oily / greasy foods and the diarrhea. I have been on it for five days now and have already lost about six pounds. I expect that that will probably slow down. The diarrhea is also decreasing now that I'm recognizing what I can and what I cannot eat. I will stick with it, in hopes of becomming pregnant. We have been trying to conceive since I was eighteen, and Clomid didn't work. So we're doing the Glucophage in addition to a double dosage of Clomid to see if that will help any. F 25 5 days
7/29/2007
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 4  type 2 diabetes nausea and occasional reflux between 1.5 and 3 hrs after taking, also never go to bed within 4 hours of evening dose.. Effects gradually worsened for maybe 8 months but have now greatly reduced at about 20 months. Also energy very low for same period; no reduction. Seems to control sugar fine. M 54 20 months
7/28/2007
 1  PCOS Insomnia, foggy-headed feeling, gastrointestinal effects If you take this med and start to experience insomnia, stop taking it immediately. This drug almost destroyed me. Insomnia is not listed as a side effect, but I wrote to the FDA about it, in hopes to save someone else. The insomnia did not reverse once I stopped taking it. F 31 21 days
7/28/2007
 4  Pre-diabetes/TypeII-Dx in flux Loose stools; GI pain, gas & bloating; Fatigue Worked up to 1500 mg over 3 weeks. GI discomfort at first w/extreme fatigue upon each increase in dose. Added B12 vitamin & Citrical -seems to have helped w/energy level. BG levels have been great from the beginning. Decreased appetite. Worth sticking it out through adjustment period. F 33 4 weeks
7/27/2007
 2  Diabetes type 2 Stomache pain,nausea, bloating, flatulence, metallic taste and very dry mouth - everything tastes rubbish, headaches, dizziness (almost a hypo feeling) WEIGHT GAIN, CONSTIPATION AND HAIR LOSS, HAIR LOSS!!!! Have been taking for 10 months. Blood sugars have reduced somewhat but not as much as I had hoped considering all the side effects I am having to cope with. I was taking 3 x 500 and had to reduce to 2 x 500 due to bad stomache pains etc. Still feeling most side effects, some days feeling really grotty. Was told things would get better but I'm still waiting. Worst visible effects are HAIR LOSS and weight gain - I am aready 50lb + overweight and really disappointed when everybody else seems to be losing weight on Glucophage. I would love to exercise but unable due to very arthritic back and awaiting knee joint replacement surgery. __________________________________________________ >>>>>Type 1 Diabetic 3/12/2007: says she is the only "actual diabetic". Well, excuse me, but I must point out that Type 2 are as diabetic as Type 1 in that we are unfortunately just as likely to have serious complications<<<<< F 73 10 months
7/27/2007
 5  PCOS Diarreaha.....occasional upset stomach Lost 20 lbs and have a peroid....even though only for 2 days F 33 2 years
7/25/2007
 2  PCOS/ Pre-Diabetes Bloating, abdominal discomfort, gas, nausea, extreme headaches, hot and cold flashes I began taking in 8 months ago at 500mg once a day and now take 500mg twice a day once in the morning and once at night. I have not experienced any weight loss, energy, or decrease in facial hair growth. I am scheduled to go back to the endocrinologist in 4 days and hope he has something better to suggest. The benefits are not worth the side effects to me. F 30 8 months
7/20/2007
 3  PCOS, hoping to also lose weight I just started this med yesterday, So still new to it.I have gained lots of weight over past 2 yrs and I have children and not having more,I had a baby last year and it seems this pcos just developed after having him.My doctor ran blood work to determint the pcos. My biggest concernis the the weight as well as hoping to regulate my periods back to normal.At this point I am hopeful and would be willing to deal with the upset stomach side effects if some of the weight comes off. Does anyone have any feedback about how long it took for the weight to come off and how long before periods were normal? I know I need to give it time to work but I am anxious for results.I really can't rate this med untill more time on it.I am looking for others that have had positive effects from this med. F 27 2 days
7/19/2007
 3  PCOS/ Trying to conceive Diarrhea,Headaches,Mild Fatigue When I became pregnant with my son 4 years ago, it happened quickly.This time it's taking alot longer. I was diagnosed with PCOS in June when I decided to visit the doctor after not having a period since March 27th.An ultrasound done on my ovaries confirmed that it was PCOS. I have obviously had this along time because a "normal" period for me would come every 8-10 weeks ( when I wasn't on the pill).My girlfriend who also has PCOS told me about Glucophage so when I seen my doctor, I was well informed.She said she was pregnant in 6 weeks. Since taking this, I've had some diarrhea, headaches and a little fatigue. Within the last week, my breast are sore and I my fatigue has increased.....fingers crossed! I'm hoping to get pregnant soon with my 2nd and last child. If anyone has any feedback with success or advice, I welcome it! F 34 6 weeks
7/17/2007
 3  PCOS I just started taking this medicine today i'm kindof young (17) but i've never had my period and was diagnosed with PCOS. I really hope this makes me regular reduce hair and lose weight i hope i can handle the side effects any one like me can email me or just to talk about it would be nice F 17 1 days
7/17/2007
 3  PCOS/Infertility/Reccurrent Misc. Cramping, nausea, vomiting, diarea, I am highly suspiscious that it will work. I have PCOS but am not overweight, excercise regularly and eat a low GI diet. Nonetheless, after multiple miscarriages - I am willing to try anything, so am on this and Clomid and then Progesterone when we get pregnant. Good luck to us all. F 34 4 days
7/16/2007
 5  PCOS, Insulin Resistance nausea, diarrhea, lots of gas and burping! :-) They eventually went away, thankfully. I lost 40.5 pounds the first year. I've now been on 1.5 years. I tried to step down this year and began rapidly gaining weight again. I have now gone back up a dosage and my weight has seemed to stablize. In the final outcome I've now gone from taking 4 500mg tables per day to taking 3 500mg tablets per day. I am hoping that additional weight loss will make me healthy enough to step down further on the medications. I do a cardio workout 4 to 5 times per week. And, I've now added strength training three times per week through Curves for Women. F 47 1.5 years
7/7/2007
 1  type 2 Heart palpitations, pain in middle of stomach just under the sternum, felt like tennis ball, cramps and diarhea. My reading has not exceeded 130 (14 day avg 113) After stopping the medication, have not seen increase but have started exercise and diet regime. M 62 25 days
7/7/2007
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 5  primarily insulin resistance, PCOS Some gas and diarrhea for the first month while on 1000mg per day. After reading this site, I cut my pill in half and took 500mg in morning and 500mg at night - that seemed to help a little. Guess I knew that there would be these side effects, so I was already determined to stick it out. I did lose about 3 lbs in the first month. When I increased up to 2000mg per day (1000mg in am & 1000mg in pm), I had a little of the loose stools come back but that did not last as long as the first time (maybe only a week for my body to get used to this higher dosage). I started Metformin at 1000mg in February. I read on sites like this that some women didn't experience benefits until they went up to 1500mg, 2000mg, or even 2500mg. I also saw a study that showed the same thing - that 1000mg and less didn't produce enough substantial benefits for weight loss and/or PCOS. Called my endo the first of March and asked that he move me to 2000mg per day (1000mg in morning & 1000mg at night). Only then did I really noticed benefits. In fact, before that I almost stopped taking Metformin thinking it wasn't doing anything except giving me the urge to go to the bathroom. Only when I went up to 2000mg did I notice a great reduction in sugar cravings and even decreased hunger overall. Had to actually make sure I ate frequently enough so I wouldn't get too low of blood sugar. Prior to this I was a sugar freak addict my whole life. I could go through a whole bowl (or pint!) of ice cream and it wouldn't even register with my body or mind. Now, I put th F 38 5 months
7/5/2007
 4  PCOS and Diabetes The same GI problems listed here. But I've found that the intensity of abdominal pain is caused by the sheer amount of carbs I've eaten. Over-indulgence leads to pain. I no longer have a problem taking the drug. I've also experienced decreased appetite and carb-craving. I've been taking metformin for 7 years. I've lost 70 pounds (still 280) and I have a regular period every month. I never used to have one at all without forcing the issue with drugs. I can no longer control my blood sugar with metformin alone though. F 38 7 years
7/1/2007
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 2  PCOS Nausea, diarrhea, headache, fatigue, lack of appetite I've only been on this medication for a few days so I'm unsure about whether or not I'm satisfied with it. I cannot eat anything I USED to eat. Now, I eat just to keep from feeling sick. I've had irregular bleeding for months straight and this medication seems to make the bleeding a bit heavier. I feel completely drained and sleep most of the day. I can't eat anything with sugar to boost my energy level as it only makes me more sick. I'm hoping the weight loss will be worth it but at this point, I'm thinking about how much happier I was when I felt good and could eat the things I want. F 24 4 days
6/30/2007
 5  Type II Diabetes Diarrhea, dizziness This drug made me lose 50 pounds in six months. Then I went off it and gained back all the weight eventually. F 25 1 years
6/27/2007
 4  PCOS/infertility diarrhea I took metformin four years ago and then again two years ago, resulting in two successful pregnancies after being unable to get pregnant. Now I am taking it again to help with insulin resistance and weight loss, but I am having a harder time with my body adjusting to the diarrhea. I had my gall bladder removed after my second pregnancy, and so I wonder if that has something to do with the bigger problem with diarrhea? F 36 3 weeks
6/26/2007

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