GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Diabetes Type 2 I started taking it 2 years ago. Initially I experienced diarrhea but I was losing weight so I put up with the diarrhea, eventually it went away. I have lost 40 lbs. over the past 2 years since I started taking Glucophage. My A1C is now normal. F 55
12/10/2008
 3  pcos I have been on this for 4 months now at first i was getting diaerha a lot then i read up on the insulin resistance diet (kinda like low carbs) and it has subsided a great deal. i am gassy still sometimes though. I have not lost any weight but i have not gained any either. i was dissy a lot. i talked to my aunt that is a rn and she said i need to check my blood surgar because it is most likly low if i am getting nausa and dizzy. so now i make sure i have some hard candy with me all the time. i was taking Glucopauge and another drug i can't remeber how to spell it something like sprolatine (waterpill) to get my acne and hair growth under control. since ttc i have stoped taking the spro. and just metiformin but i have not had a period since taking them. I now have to take provera to get that started. i am not sure if the metformin is doing the job that ob/gyns want it to do for me and hlep make me ovulate. seeing i have not had a period i am not ovulating. but i will see what happens now that i have stoped taking the other drug. we will see in three months. F 24 4 months
12/10/2008
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 3  PCOS and Insulin Resistance More Hungry, sligth body malaise, hair loss, sweaty I am taking the medicine for two weeks now and I noticed that I grew more hungry than before (I wonder why cause it should suppress you to eat more right?) I feel more tired and some gas is there after eating rice/bread/potato. I wonder why is this happening. Hair loss became worst and I feel tired and I feel that I lack sleep even though I sleep for 10-12 hours. F 27 2 weeks
12/8/2008
 5  pcos a little diarrhea and gas the first few days, a little difficulty concentrating, but that was all for some reason, it helped me loose weight. i began it 9/6/08, and have lost 14 pounds. it also helped me regulate my hormones, which helped anxiety, but unsure why. F 36 3 months
12/7/2008
 3  to reduce belly fat gas, diarrhea, but no nausea. type II diabetes in my family, so wanted to prevent onset; waiting for benefits; waistline of pants looser after just 2 days! M 48 4 days
12/7/2008
 4  Diabetes Type II, PCOS I instantly felt very lethargic and needed over 12 hours of sleep. In the first week, I had body ache all over, slight diaarhea if I ate fried foods, Feeling queasy all the time, & bloating. The good side : it drastically improved my sugar level from 300 down to 99-108, under a week of being on the medicine. Weight went down 2kg under 2 weeks, with no excercise at all. Recommended! F 37 12 days
12/3/2008
 2  diabetes didn't help blood sugar that much F 77 3 months
12/2/2008
 2  PCOS Explosive Diarrhea and nausea. So far having extreme hunger as well. I was on this off and a few years ago for over a year. 2 different doctor's put me on it. It made me so sick and miserable, especially each time they increased my dosage, that I quit taking it for the past few years. I also never lost any weight on it. My OBGYN put me on it yesterday, so I could give it another try. I have been losing my hair since I was 15 and have always had trouble with my weight. I was able to lose 40 lbs off of the meds and kept it off for over 2 years, but have gained almost all of it back in a very short amount of time... despite training for half marathon during this time. I took it for the first time again last night and was up from 3am until 7am with massive cramping and diarrhea. I am starting out just 1 500mg tab a day and then add each week. I hope I don't have to go through this for a long time again. It's unbearable for any length of time. Most of the posts I've read said that they lost hair, but all of my endocrinologists said it would help me get some M 29 1 days
11/20/2008
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 5  PCOS diarrhea first week, slight stomach pain Taking 500 mg 2x daily...got my period back within one week of starting the medicine...have already lost weight and seen my pants get looser. Only downside is not able to drink and fatty foods upset stomach. Keep to a low carb, healthier diet and will work great! F 20 1 weeks
11/16/2008
 2  Type 2 Diabetes extreme nausea and diarreha and some head aches and heartburn I was put on metformen for Type 2 Diabetes becuase I am insulane resistant. I hope this passes because I can't keep going with this nausea every day. F 38 5 days
11/11/2008
 1  borderline diabetes Depression within a week of taking metformin. Doc said that was very unusual, but to stop taking it. Then a friend of mine told me that it suppresses TSH (thyroid stimulating hormone). I have no idea if that is correct, but I am hypothyroid. If it suppresses TSH, I would think that the doctors would know that and not prescribe it for someone like me. Has anyone else ever heard this or had this experience? F 62 1 weeks
11/4/2008
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 1  PCOS My hair started to come out in chunks! I had thinning all over and lost a great deal of hair at the temples. I had really thick, beautiful waist-length hair and I am devastated. I was prescribe 1000mg per day for PCOS. After 6 weeks I started to see lots of hair loss from all over my head. In particular my hair has now receded at the temples by about 2 or 3 cm. I stopped taking the drug about a month ago and the hair loss has stopped all over but I am left with the receding hairline at the temples. I am hoping it will grow back, but it doesn't for men when they have male pattern baldness. F 33 60 days
11/3/2008
 1  Diabetes Type II I had no side effects at a low dose, but as the dosage was increased to bring down my blood sugar, I developed chronic diarrhea! I lost 12 pounds in six weeks and couldn't leave the house without taking a dose of iodium. I was planning my daughter's wedding during this mess! I was very angry with the doctors for not believing me when I said it was the glucophage causing the diarrhea! THey made me take stool sample and other tests for three weeks before everything came back negative for intestinal bleeding, worms, or other infections. As soon as I went off the glucophage, it all stopped! Proof enough for me. Apparently this is a very rare side effect. I know my body and it told me something was very wrong. F 56 7 months
11/3/2008
 3  PCOS/ Insulin Resistance consitpation originally then an increase in bowel movements along with occasional nausea feeling better overall, only been on it a short while, despite numerous discussions with both GP and endocrinologist. we shall see how it goes, i reamian optimistic F 38 5 days
10/27/2008
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 2  insulin resistance more frequent bowel movements slight decrease in BS increased liver function I have been disappointed that I have not seen any weight loss at 2000mg dosage. I have not had any discomfort or really negative side effects so far, but after 6 months I expected to see some more positive effects, especially with my 1200-1500 calorie low carb diet, and 40 min workouts 4-5x a week. I also have bilateral lymphedema and am concerned that the met may be negatively effecting that and the lymphedema may be limiting the positive effects of the met. Like most MDs, my endo appears to know little or nothing about lymphedema. F 59 7 months
10/26/2008
 5  PCOS loose stools/GI symptoms during first 2 months Weight loss This is a miracle drug for me. Gained lots of weight over 4-5 months due to PCOS. First 3 months on metformin and I lost about 25lbs :) I was already on a controlled diet (1400-1500 calories) and working out (1-1.5hrs 5xweek). It's like metformin just helped make those efforts actually count for something. Yes, it was uncomfortable when I first started taking it. Stick with it. You'll be happy in the end. I take 1000mg 2x day now, but started with just 500mg 1x week and ramped up over a 4-5week period. This greatly reduced symptoms. Initially, i was given the xr version at 1500mg a day (straight off) and couldn't handle it at all--threw it right back up. Careful introduction of the regular (non xr) version has been great F 25 1 years
10/24/2008
 3  PCOS & insulin resistance Diarrhea, pain in muscles, joints, gut. I had some success fighting the diarrhea with fiber (psyllium husk) supplementation. I just stopped using glucophage because I got scared reading about lactic acidosis because I have been a heavy drinker and now am moderate, still working on cutting it out altogether. However, I think my symptoms were common and not related to lactic acidosis. I take a heaping tablespoon of PSYLLIUM HUSK twice a day mixed in water. It was difficult at first, until I purchased a $20.00 little milk frother (it has a motorized mini wire whisk and is battery operated) at Linens & Things (like Bed & Bath) and it mixes the fiber and water FAST so I can chug it before it gets all lumpy and nauseating (think drinking ground unflavored oatmeal). Increasing your fiber reduces all the stuff I'm working on: obesity, diabetes, high blood cholesterol, cardiovascular disease, gastrointestinal disorders. http://en.wikipedia.org/wiki/Dietary_fiber Let me know via posting if it helps. F 42
10/18/2008
 1  Type 2 diabetes No side effects on 500 x 2 other than weight gain and it worked just fine with keeping my blood glucose in check BUT ------- you people need to be aware that this medication will affect your kidneys. I have now been taken off this med due to problems with my kidneys and started on Januvia (which is doing absolutely nothing for the blood glucose levels). Make sure you have labs drawn at least every 6 months to check kidney function (3 months would be better). F 69 3 years
9/28/2008
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 5  Impaired Glucose Intolerance Slight headache the first day. No other side effects so far. No problem with diarrhea or abdominal pain. Decreased appetite. I noticed that my appetite has decreased. I couldn't finish a sandwich. I have alot more energy. I didn't have to take a nap today. I had energy to exercise 30 minutes on the elliptical. I was able to keep up with my 7 year old son..usually he wears me out and I have to lay down. Now he is sleep and I am up. If appetite reduction and energy stay the same then I can see why so many people lose weight. I need to lose 40 lbs. I will post again with further results. F 41 2 days
9/27/2008
 4  Weightloss/PCOD No serious side effects, only a little diarrhea. I am only taking 500mg per day. I feel like I have more energy, also, I feel full very quickly and do not eat more than I need as a result. F 50 14 days
9/25/2008

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