GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  PCOS I experienced stomach aches when initially taking it and still do occassionally if I don't eat enough food before taking it. It seems to help if I eat half of my meal, take the medicine, and then eat the rest. I started taking Metformin at the beginning on January to help with my PCOS. I am taking 1000mg twice a day. I still haven't had a period and was wondering how long it takes to regulate? I have taken pregnancy tests and they are negative. Any suggestions? F 27 1 months
2/4/2009
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 4  PCOS Nausea, Light-headedness, stomach cramps follwed by diarreha that comes on very quickly within minutes of cramps. When I first started taking it I felt horrible for the first few weeks. I would feel fine and then would have to lay down and close my eyes due to the light headedness and nausea. Just felt sick. Dr. recommended taking entire dose at night after a good dinner which worked well. I still get light-headed and am dealing with the cramps/diarreha. My periods are still not regular, my cholestrol has come down significantly. I have lost 30 pounds and do experience severe light-headedness if I miss a meal. M 34 1.5 years
1/28/2009
 5  P.C.O. {polycystic ovary syndrome } Update of a update lol. Ive came here a couple times over the years. So far 130 pounds weight loss, regular periods. I still swear by glucophage / metformin. It has helped me with P.C.O so much. I still ever so often get the lose bowels or constipation but not no where near as often when you first get on it. I take 1,000 mg x 2 a day. Your welcome to email me any questions. There isn't anything I haven't experienced or been thru on it that I get ashamed to talk about lol. I wish this site had been around years ago when I started lol F 31 2 years
1/27/2009
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 3  PCOS loss of appetite, nausea, light headedness (if I go too long without eating) Hoping it will regulate my cycles, reduce facial hair growth, and help with fertility later on. Still no sign of my period, so I'm hoping it'll eventually help with that. Taking 500mg 2x a day right now. Need to get updated hormone levels this week to see if I need to increase dosage. F 30 4 weeks
1/27/2009
 4  Type 2 Diabetes Explosive diarrhea 15 minutes after taking-Was on 1000mg 2x day but now better with lower dose of Metformin XR. Have lost 26 pds.Bloodd sugars are normal. F 54 3 years
1/26/2009
 5  Diabetes Mellitus Type 2 for the first week of taking metformin i had bouts of diarhea. but that faded with continued usage. Apparently i'm very responsive to this drug. Blood sugars are averaging out to 102 in the am and 87 in the pm. Its working great. Especially once the initial side effect of diarrhea wore off. M 36 25 days
1/24/2009
 4  Possible PCOS, Insulin resistance Stomach upset (with sugar), flatulence, some nausea, and loose stools (depending on the amout of sugar I've ingested). This is a great medication as long as I control the amout of sugar I take in. I've been on it since August '08, however taking it consistantly since the end of Novemver. I've lost 15lbs since November. I've noticed I'm not quite as hungry. i take 2 500mg twice daily. F 25 6 months
1/23/2009
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 3  Insulin resistance & PCOS HAIR LOSS, HAIR LOSS, HAIR LOSS! I experienced the same side effects as everyone else, but over time, the hair loss worsens. My 2nd month on Met-It worked wonderfully for my PCOS & my period resume the 1st month I was on Met. The side effects has lessen but weight loss stopped (I lost 14 pounds in 1st month,with no excercise) Hair loss is very evident now. F 37 2 months
1/20/2009
 5  PCOS Embarrassing Fart Attacks, smelly GI attacks, etc. Hello Everyone-This has done the trick to help out my PCOS. However, I have experienced the horrific Flatulance. My goodness you would think I'm some nasty old man :-( Overall I am pleased with the results for PCOS...Just need some perfume for my stinky butt! F 32 3 months
1/19/2009
 2  PCOS Diarrhea,loss of libido,severe PMS,mood swings I have been taking Metformin for about a year now and I have had pretty much the same side effects as everyone else.I have also noticed that I have severe acid reflux recently. I still have horrible diarrhea and I have to urinate constantly. I just do not feel emotionally like myself. As for my periods they are better than before but they are still not regular. I already have two wonderful children and we are not trying for more so I am not taking for any other reason that to help with my hormones. I am going to get my yearly liver, kidney, and hormonal tests done and depending on what the tests say I will more than likely quit taking it. I feel I have given it a fair chance and all the side effects are not worth it for me. F 29 1 years
1/19/2009
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 5  PCOS F 31 3 months
1/16/2009
 2  PCOS, weight loss Bad gas, rumbling stomach, vicious diarrhea, tiredness, headache, dizziness I just started taking the drug yesterday, and after three doses (500mg each) and reading this board, I think I'm going to have to stop. Right after I took the first pill I got bad gas, and then had insane diarrhea when I got home. I'm already on a high protein, low carb no sugar diet, so I don't know what else I can do on that end. I feel like crap. And I've already got thin hair -- don't need to lose it. :( F 28 2 days
1/14/2009
 2  Type 2 Extremely tender and inflamed joints, also muscle pain At 750 mil/day, it was enough to drop my sugar from 124 to 103, however, the side effects were unacceptable. Although others claim a weight loss, I actually gained 15 pounds in the four months that I was using it. I could have lived with this, but the joint pain in my knees and hips was so severe that it even hurt when I was trying to lay in bed at night and I could no longer exercise in the morning. I dropped the dose to 250 mil/day and most side effects have disappeared with sugar now at about 115. This is about as close as I can compromise. M 56 4 months
1/12/2009
 5  Type 2 Diabetes weight loss, Loose BMs & Excessive flatulence Let me say that overall I am very please with this drug. it brought blood sugar levels down for my doctor to be happy. MAKE SURE you buy some Febreeze,GLADE, or AirWick Deodorizer though. I FART like crazy and it stinks BAD!!! It's embarrassing at times, because I think of myself as a proper lady, but the med has been worth it for my diabetes F 27 4 months
1/6/2009
 5  PCOS; insulin resistance a little loose bowels at first; subsided, with no other symptoms. Miracle.... an answer to my prayers. I lost weight, gained energy, and started having a regular period. All the symptoms of the PCOS cleared up... amazing. I take a fairly high dose (1000 mg, 2 x a day), yet I have no problems. Severely insulin resistant; glucophage is the only thing that has ever tackled it. It does upset the stomach in the beginning, start out slowly, build up as needed. I would suggest, for those who have major gastro issues, there is a possibility one's diet interacts with this medicine; the more sugar and carbs one takes in, the more likely, I think, one may have some continued gastro grief. It makes sense, this med does modify food. F 33 9.5 years
1/2/2009
 5  Diabetes Flatulence, Nausea, diarrhea This medicine has greatly helped with my diabetic condition. However, I have Explosive FARTING spells. The flatulance is much stinkier than normal which is embarrassing for a woman my age. I have an understanding boyfriend though.... F 28 1 months
12/30/2008
 3  PCOS Very acute nausea, acidity, diarrhoea and after taking it for 8 months i realised that my hair has thinned down to 1/3rd of what they used to be. In the earlier 6 month period i did lose 8 pounds but gained back after i stopped. Started again after a period of 2 months but not lost any weight this time around. I am on 1500mg everyday for past 8 months...After taking it for 6 months initially my cysts cleared however they appeared again after a break of two months so i was on metformin again...same dose.However, i have noticed a great deal of hair loss and i am wondering whether it is any way related to metformin though i have read that there is no proved linkage scientifically. but hair loss is more pronounced now and it is making me very anxious.This medicine does work for PCOS. F 26 240 days
12/28/2008
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 5  Diabetes Type II, PCOS, Insulin Res I rated 4 weeks ago abt Met-I started off on met on 22 Nov & everything stabilises by 25 Dec & my period showed up today! Am trilled as my period are rare & Met helped greatly! I dont feel well the first 2.5 weeks until it kicked in. The nausea feel are always there but it showed results and improvements. My weight dropped 14 lbs in 5 weeks and my health got better. Anyone who felt ill on Met, dont give up! Just hang in there!! F 37 4 weeks
12/25/2008
 1  Type 2 diabetes sudden and urgent need to have bowel movements; nausea, stomach cramps--felt increasingly unwell. When dosage increased, symptoms increased, and occurred daily, and often several times a day--was afraid to go anywhere...didn't realize just how sick it was making me, until a wellness nurse suggested I contact physician, and ask to discontinue...was completely back to normal and feeling so much better in days!!! F 52 2 years
12/22/2008
 5  diabetes type 2 for XR: excessive farting, stinkier flatulence, mild nausea (~2 weeks), mild diarrhea for non-XR (1.5 weeks and counting): nausea, bit of soreness, loss of appetite, extremely smelly flatulence, diarrhea The XR I started off at 500 mg/day in the evening and had initial flatulence and nausea and would improve after 2 weeks until I cranked up the dosage again up to 2000 mg/day. The flatulence then got to the point where it was extremely embarrassing even though my glucose control was pretty good as long as I was reasonably disciplined (ie, usually stayed below 160 as long as I didn't decide to eat a whole bowl of udon noodles or a big chunk of cake). Then I went off Metformin and tried Januvia, which allowed people around me to breathe easier but sent my A1C up to 7.6 (got my A1C to around 6.5 or so in a few months from a 9+ on the Metformin originally) Now I'm on JanuMet with the non-XR Metformin for a week and a half and feels like the side effects are worse this time around but I've heard that the XR is a lot easier to tolerate. So far I'm back to 115ish fasting instead of the "please let my fasting be below 140" ritual with Januvia. Let's hope my digestive system get F 29 10 months
12/18/2008
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