Average Rating: 2.9 (276 Ratings)

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Compare TRINTELLIX with similar:

 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

 3  Depression Slight nausea, took at night, didn't last long. THE COST IS OUTRAGEOUS, DISGUSTING AND SHOULD BE ILLEGAL. Discontinued use because insurance wouldn't cover it. F 50 4 days
5 mg 1X D
 5  Depression No side effects on 10mg. So far happy with Trintellix M 56 1 months
10mg 1X D
 5  Anxiety & Depression I had been on Trintellix about 5-6 years ago with excellent response to my depression. I didn't experience weight gain or the sexual side effects I'd experienced on other meds. This time however there were sexual side effects and I've gained 6-8 lbs since the start of Trintellix. I was on it about 5 months. This upset me enough to discontinue the drug. I think it may affect a person differently at different stages in their lives - such as perimenopause. F 49 100 days
10 1X D
 4  Anxiety depression Extreme upset stomach and nausea with mild headache after taking with or without food. Has changed my mood and thinking. Amazing. But the upset stomach is brutal. I dread taking it every morning knowing what's coming and lasting for two hours. F 59 2 months
5 1X D
 5  Anxiety and depression Caused nightmares if I took it at night or upset stomach if I took it without food. As long as you take it with food during the day youíre good Life changing. I was a wreck before this med. Iíve tried every antidepressant out there. This worked the quickest and has the least amount of side effects. F 24 2 years
 1  General anxiety Severe nausea, vomiting, diarrhea, dizziness, tinnitus, headache, severe insomnia Horrible. Made me very sick and unwell mentally. Would never recommend F 40 5 days
20mg 1X D
 2  Anxiety. Mild depression Nausea, sedation, low energy, lack of interest, cannot exercise as well, slight balance problems Good sleep! Partial decrease in anxiety, but overall feeling of being inhibited . Can't wait for it to wear off! M 54 18 days
5 MG 1X D
 1  Depression I started at 5 mg while weaning off my Cymbalta. I experienced a noticeable increase in irritability and had trouble falling asleep, but it worked to elevate my mood during the day a little. When the doctor increased my dose to 10 mg I experienced severe nausea, vomiting and diarrhea. Anxiety increased a lot. I do not normally experience any stomach issues with medication but this reminded me of taking pregnancy vitamins on an empty stomach. F 57 3 weeks
10 mg 1X D
 1  Anxiety, depression Nausea, worsening depression, anxiety, constipation, lowered sex drive, irritability/anger, restlessness does almost nothing for anxiety F 4 months
20mg 1X D
 3  Anxiety/depression/obsessive though No sexual side effects. Restless and hard to sleep. It helped me with my depression. Seemed to give me energy and motivation. However, I just felt restless and didn't sleep well while taking it. Did not help my anxiety, although it did improve my mood. I would recommend trying it for depression especially if you want something without sexual side effects. M 41 28 days
 3  MDD First three weeks fine. Then itchiness, extreme bloating and feeling more anxious and confused. Very expensive. F 62 60 days
10 1X D
 1  Depression Extreme nausea when dose increased from 5 to 10mg. Anxiety, itching, dizziness several times a day, increased migraine episodes after 4 month taking brintellix and no improvement at all in my situation. I feel my head is always confuse, experienced several panic attacks and I fear the future. Weight gain was also a side effect after 3 month treatment. I must quit this drug ASAP F 45 5 months
10mg 1X D
 1  Major Depression Irritability, leg pain, suicidal thoughts, weird and sometimes disturbing dreams. At first it seemed like a miracle. Suicidal ideation I'd been having disappeared within several hours of first dose, I was thinking more clearly and for 3 days was floating with happiness. Then, with no change in dose, I experienced worsened depression, anger and irritability and more severe suicidal ideation than before I started. Cutting down to 5mg did not alleviate the negative side effects. I've gone back to Cipramil (Celexa) which I went off to try Trintellix. It could be a wonder drug for some, but it was a nightmare for me after a promising start. On the plus it seemed relatively easy to stop ie no SSRI withdrawal syndrome. F 53 2 weeks
10mg 1X D
 1  Anxiety Insomnia , bloating ,gas ,lack of appetite weird tingly sensation Abnormal dreams, sexual dysfunction It's an absolute nightmare to withdraw off M 47 34 days
5mg 1X D
 3  MDD and GAD Nausea, dizziness, extreme tiredness in the evenings, itchiness Helped my mood, motivation and mental clarity in the morning. The fatigue later in the day is a big problem however- need o get it addressed. F 45 2 months
15 1X D
 4  Depression Itching some bad dreams reasonable for me although still some flashbacks of traumatic incident M 58 2 years
15 1X D
 4  Mild anxiety and depression No side effects at all. Felt better, less anxious, more focused and generally happier and in a better mood. M 46 1 years
15mg 1X D
 1  Depression Fatigue - bad dreams - diarriea - Anxiety -mood more depressed Started taking brintellex 5 mg for the first one week. Then continued 3 weeks with 10mg . I feel more depressed with fatigue all day and dizziness . Had many bad dreams non stop while sleeping . I am deciding to stop this medication after seeing my doctor . I don't recommend brintellex F 45 1 months
15mg 1X D
 5  anxiety, severe panic attacs when i first start taking it a bit of weight gain and sexual disfunction(not severe like with SSRI) managable. now i take it with 300 wellbutrin and i have incrased libido, no weight gain for now . great combo! M 27 35 days
5mg 1X D
 5  Generalized anxiety disorder Mild nausea initially and some emotional blunting and reduced cognition at higher doses which resolved with lowering the dose. Very fast onset of effect. By far the best tolerated antidepressant I tried. M 67
5mg 1X D

BRINTELLIX  (VORTIOXETINE HYDROBROMIDE):  This medication is used to treat depression. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Vortioxetine is an SSRI (selective serotonin reuptake inhibitor) and serotonin receptor modulator. This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.   (Sources: U.S. Centers for Medicare Services, FDA)