TRINTELLIX Reviews (VORTIOXETINE HYDROBROMIDE)

Average Rating: 2.8 (307 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

BRINTELLIX  (VORTIOXETINE HYDROBROMIDE):  This medication is used to treat depression. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Vortioxetine is an SSRI (selective serotonin reuptake inhibitor) and serotonin receptor modulator. This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.   FDA Approval Date: 2013-09-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR TRINTELLIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Borderline personality disorder Switching to Brintellix from Celexa due to untenable and rapid weight gain from SSRI's. Tapering down on Celexa and slowly introducing Brintellix I have noticed extreme irritability like I want to yell at someone and have very little patience. Not sure if this is because of decreasing Celexa or the Brintellix. I really hope it will help with my anxiety and depression. I have out on weight wth almost every anti-depressant out there: Celexa, lexapro, Effexor, pristiq, ability, Zoloft, Prozac made me crazy I had to get off of it. Even put on weight with Wellbutrin. A check swap analysis reports I will not metabolize Brintellix well but new psychiatrist wants to try it. Have lost a lot of hair on Lamictal but did not gain weight. Not sure if I can tolerate it and no idea where to go next. F 42 1 days
5mg
10/18/2015
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 4  Anxiety, depression bi-poler I've taken about every ssri and snri available. This one is pretty good. Doesn't do as much for my anxiety as I would like. I also take a light dose of trileptil and klonopin. Brintellix made me pretty sick at first and it took me some time to get stabilized. I won't switch, this is the best I've tried. . F 45 1 days
20 mg
10/10/2015
 2  Depression/Anxiety Loss of appetite,abdominal discomfort,fatigue,increased depression,constipation. Stopped 3 weeks ago,symptoms worse. M 58 3 weeks
10
9/27/2015
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 4  MDD and Anxiety Nausea, Itching, Diarrhea (all symptoms disappeared within 3-4 weeks) I am a young African American woman who has been living with depression and anxiety for 5 years. I've tried many many different medications with no relief. In November 2014 I started taking 10mg of Brintellix and noticed a difference in my depression within weeks. Usually during the fall and winter months I would be severely depressed, not leaving my house and many times not even leaving the bed for days at a time but since starting Brintellix that has greatly changed. In the summer of 2015 I started having panic attacks 1-2 days a week which I was told was due to my body getting use to the dose I was on. My dosage has since been increased to 20mg and I'm continuing to get relief from my depression. F 32 10 months
20 mg
9/23/2015
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 1  Depression and anxiety Horrible, horrible experience with this drug! Could not sleep; anxiety increased ten fold and I became irratible, nervous, emotional and light headed. I had to stop taking the medication. M 49 3 weeks
10 mg
9/19/2015
 4  Anxiety Bloating and excessive gas after eating for the first week. No constipation. GI symptoms went away after about a week and a half. Feeling normal now, anxiety is under control. Hoping I can lose weight on this medicine as Effexor caused a 25lb weight gain in two months. M 24 3 weeks
5 mg
9/16/2015
 3  Anxiety Massive weight gain and I exercise more and cannot lose weight. Has helped with anxiety but gaining all this weight has now made me depressed. Don't know what to do I do not want to try another medicine and go through all that. M 40 1 months
5mg
9/15/2015
 5  Anxiety and Depression None Has Greatly reduced anxiety and depression F 53 14 days
10 mg 1X day
9/13/2015
 2  Major depression, General Anxiety This is an update of my initial review from July 2015. I had only been on the med a week at that point. I first found this to be very promising. Side effects were manageable and I had a very brief period of clarity and motivation which led my doc and I to decide to bump up to 10mg. Well, I'm not sure how that went because I was asleep 90% of the time. I could not stay awake. Generally, I have issues with insomnia. This was like 2 or 3 naps per day and sleeping through the night and into the afternoon. No good. Back to 5mg. I haven't noticed any more "up" days but what I've finally realized is the ridiculous amount of sweating that I've been concerned about, complaining about, disgusted about, is more than likely from this med. It has become such an embarrassing problem that my anxiety is increased. I literally am dripping sweat from my hairline and back and the rest of my skin is clammy. It's unbearable now. I thought I'd see if it would subside like some of the other side ef I've been on many SSRIs and SNRIs and have never experienced the excessive (REALLY excessive) sweating as with this medication. It has been mortifying and uncomfortable and there is no way that I can continue like this. I wasn't seeing much, if any, improvement anyway, so I'll be glad to get rid of this one. F 41 2 months
5 MG 1X day
9/10/2015
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 2  Major Depression Nausea for weeks that finally stopped, muscle aches and pains Seemed to make depression worse. Constant fatigue and no motivation, apathy. F 46 6 months
10 mg
9/10/2015
 1  Anxiety w/ some Depression Nausea, dizziness, headaches, anger, fear, teeth grinding, jaw jittering Awful. Felt like I was on speed. No improvement of symptoms, in fact anxiety was increased. F 32 6 months
10
9/8/2015
 2  MDD GAD Switched off lexapro due to excessive bruising and my psych dr gave me samples of this and deplin because I have trouble converting folate. First day of brintellix I didn't notice anything, second day I took it with my birth control and ended up vomiting. Called my md , said to cut it in half and if it's worse to take Dramamine or pepto. So I went two days without anything and tried again, first night I was fine and then tonight I threw up again. Not sure if food is making it worse or not but my dr said to take it at night, which I have been. I can't tell a difference yet with the medicine. I've only been focused on the nausea and vomiting. It's bad. F 28 1 days
5mg
9/6/2015
 4  depression Nausea the first week. I feel chilled out and happier. I'm enjoying the smaller things in life now. My sadness and agitation has gone. The only thing I HATE is my INCREASED appetite. I have been gaining weight. I'm wondering if my doctor can prescribe me something for appetite or weight loss.. idk F 24 1 months
10 mg
8/11/2015
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 1  depression Horrible swollen feet. So bad that I cannot walk. Stopped taking it for four days and feet still extremely swollen. Had a metabolic panel done today. F 50 7 days
20 mg
8/10/2015
 4  MDD GAD Mild headaches first week. Brain zaps due likely to coming off cymbalta (which was no good). Some insomnia but when you feel good you don't really mind. Not up all night but sometimes an hour or two later than normal. So far it has helped a lot with my depression and my anxiety which was horrible with cymbalta. Prior to cymbalta had been on Lexapro for 10 years until it pooped out. This will sound odd but am somehow more focused, almost smarter on Brintelli. I'm a professional and was reasonably intelligent before, but find my self talking smoother and saying all the right things at work. M 43 1 months
10
8/7/2015
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 4  Depression and anxiety Just concerned that my flu symptoms may be from the Brintellix Brintellix has stabilized my mood. I`m less agitated with my husband and I have less social anxiety however; I am worried that my consistent flulike symptoms are being caused by the Brintellix. I would appreciate any comments from others if you are experiencing this as well. Good luck and thanks for reading my comments. F 2 months
10mg 1X day
8/6/2015
 3  Anxiety and ADD Itching. Everywhere. Great coverage of my symptoms, can't stand the itching. F 41 5 days
20 mgs
8/3/2015
 5  OCD, general anxiety disorder, MDD None!! Miracle drug for me. Halfway through the first day of taking it, I stopped and realized that I hadn't really worried about anything that day. The same feeling continues today! I can think more clearly on this drug as well! F 27 1 months
10mg 1X day
8/1/2015
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 4  Major depression, General Anxiety First day or two, very sleepy after morning dose, but that has subsided. Headache for almost a week, somewhere between mild and wake-me-out-of-sleep agony. Also seems to be subsiding. Biggest problem has been major acid reflux and not remembering or wanting to eat, totally put off most foods. This is another effect that seems to be getting better. Also noticed a lot of very brief "flashbacks" throughout the day today (day 7) during which i get a one to two second flash of what I think is a dream I had but I can't quite grasp anything substantial or recall anything immediately after. It's weird and frustrating, but not painful or scary. Had been at a very low point of a depressive episode and felt relief within two days. Have been on most every SSRI at some point. I take this with Wellbutrin at the moment, not sure if that will be continued. I feel better than I have in a while and it's only been a week. I have everything crossed that the benefits will continue while the side effects subside. F 41 7 days
5 MG 1X day
7/20/2015
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 5  Anxiety and depression None Finally!!!! I love it!!!!!! F 57 5 days
10mg
7/18/2015

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