TRINTELLIX Reviews (VORTIOXETINE HYDROBROMIDE)

Average Rating: 2.8 (307 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

BRINTELLIX  (VORTIOXETINE HYDROBROMIDE):  This medication is used to treat depression. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Vortioxetine is an SSRI (selective serotonin reuptake inhibitor) and serotonin receptor modulator. This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.   FDA Approval Date: 2013-09-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR TRINTELLIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  bipolar manic depression, anxiety Extreme dizziness, nausea, muscle weakness, back of neck stiff and tight, pain behind eyes, non stop diarrhea, made acid reflux worse, made anxiety worse I am a veteran when it comes to psychiatric medications. Due to poor care over the years, I've become med resistant which is scary and overwhelming. Please remember that everyone responds to these medications different. Also keep in mind when you are doing research that these medications take at least 30+ days to get in your system. I tried to battle out the side effects and today made the decision that the bad outweighs the good. The dizziness and muscle fatigue was terrible for me. The nausea was getting better and I found that taking it at night helped. I noticed that it killed my sex drive but oddly I had some of the best orgasams. Weird! I also felt like this med was trying to work but would fade followed by extreme anxiety. I also take depakote, adderall, ativan and saphris to sleep. After 2 months and still scary low, I'm considering going off. My Dr bumped me up to 10 mg yesterday but I'm finding it hard to come up with the fight to continue a med that causes me so many side effects. Best of luck to everyone in search for their right combination. F 37 2 months
10mg
2/27/2015
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 2  Depression Nausea, headaches, blurred vision, trouble concentrating, anxiety At 5 mg the nausea was barely noticeable, but within a few days of increasing to 10 mg it was very bad. The headaches at 5 mg subsided after going up to 10 mg. I've had very brief instances of feeling better, but they fade quickly. From what I was told by my pdoc this is a medicine that will either work for you, work for a few weeks then stop, or you'll never experience any benefit from it. I had hoped that the SRI and 5-HT1A agonist effects would help my GAD/panic attacks, but I've only experienced increased anxiety at 10 mg so far. M 34 2 weeks
10 1X day
2/24/2015
 1  depression, anxiety increased anxiety, increased blood pressure was 110/70 with diovan immediately went up to 130/85, then 140/90 no real benefit, except less sleep, back to normal 8.5 hours vs almost 10 hours on lexapro and effexor F 59 14 days
10mg 1X day
2/19/2015
 3  Anxiety depression Itching, headaches, swelling in hands and feet. Very tired all the time. Easily aggitated F 31 10 months
5
2/5/2015
 3  Anxiety & Mild OCD No weight gain like with Lexapro, however, I don't have the calm, level feeling I had with Lexapro. I still have OCD "checking" of locks, stove knobs, kids breathing while asleep at night, whereas with Lexapro it was minimal. Due to $70 per month copay with our insurance I stopped cold turkey 4 days ago and haven't noticed any side effects. When I got off Lexapro I weaned myself off VERY slowly but still felt like a walking explosion waiting to happen. I have had NO itching like others commented. Sleep normally at night. F 43 7 months
20mg
2/3/2015
 5  MDD after about three weeks began to feel better. Has made a great deal of difference improving my mood, energy level and wanting to do things. added D3 after 2 months and that really helped too. finally some relief after years, I mean at least 10 years of being depressed. M 57 3 months
20mg
1/31/2015
 1  Depression Nausea, fatigue, constipation, no sex drive, irritability, itchiness. I really had high hopes for this medication. The first couple of days I experienced tiredness and nausea, but I decided to stick it out for a while. Day three my anxiety was gone, but the fatigue remained so I started to take it at night. Days went by and the symptoms just kept coming and getting worse. I ended up becoming irritable, and uncomfortably itchy. My house is a mess. I have zero energy! No anxiety, but all I want to do is sleep all day long. F 29 2 weeks
10 mg
1/26/2015
 5  MDD Nausea, stomach pain, night sweats, constipation. Side effects are not severe, unpleasant but tolerable. F 30 3 months
10
1/20/2015
 3  Severe depression Intense itching all over my body but mostly in my scalp. Also developed rashes on my arms, neck and face. This drug really worked on improving my depression. Also, it did not make me gain any weight like Lexapro. But I can't tolerate the rash and itching. So Unfortunately I have to get off of this medication. F 45 65 days
5mg 1X day
1/10/2015
 5  major depression, suicidal thoughts I was having nausea at first but my doctor told me to take it after dinner/before bed and that cured it. He told me I would feel better after taking it for 2 weeks, good after 4 weeks, and WONDERFUL at 6 weeks. I wanted him to write that statement down because I was so depressed and doubtful anything could get me out of the pit. Well, at 8 weeks I was a completely different person. I have energy, I am not prone to the ups and downs, I am finally getting my life back. I've tried many other anti-depressants (Zoloft, Effexor, Cymbalta, and a few others over the past 15 years) and Brintellix quite simply saved my life. My only issue is with my PMS induced rage, which this med doesn't seem to cure. My doctor just started me on 10mg of Prozac so we'll see if that helps. I also take Lamictal for BPD, Adderrall, Wellbutrin, Phosphatidyl-Serine, and n-acetylcysteine. Thank you, Brintellix... Now if it wasn't so expensive, even with insurance I asked the company for assistance and was denied because I have insurance...sent the follow up letter and never heard back. F 45 7 months
20 mg 1X day
1/9/2015
 1  Depression / Bipolar Ended up in ER for heart problem ....went home and a few days later woke up with my whole right side numb..right eye blurry. Went to the ER again...Seem to have nerve damage on the right side. Working with a cardiac doctor and have to see a neurologist now. I cannot drive or walk by myself when out in public due to the weakness, and messed up motor skills. My memory is not right either. DO NOT TAKE THIS MEDICATION. RESEARCH BEFORE TRYING NEW DRUGS...WISH I DID NOW F 40 3 weeks
5 mg
12/31/2014
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 4  Bipolar Depression/MDD I threw up for two weeks straight, then I started taking it at lunch instead of breakfast and that helped stop the vomiting AND nausea. Takes 30 days to feel effects...but I still have very few moments when I cry...other times I want to cry but can't F 31 3 months
10 mg QD
12/26/2014
 2  Depression/Anxiety Didn't work M 40 14 days
20 1X day
12/18/2014
 1  anti depressant Itching all over my body. I've had to itch my ears and head all the way down to the bottom of my legs. My arms, legs, and stomach are the worst! I have been itching non stop for 2 days now. Benadryl won't even help with it!! Someone at work asked me if something has changed because I was acting hyper. Having a hard time falling asleep. F 36 3 days
40 mg 1X day
12/18/2014
 1  Major depressive disorder The first two weeks taking this medication I was on 10 mg's and I felt much better it seemed, now that I am on 20 mgs my depression, anxiety, agoraphobia and feeling of over all depression has increased greatly, very bad medication for me. F 47 4 months
20 mg 1X day
12/17/2014
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 3  Depression and anxiety I cannot stop eating and it is tough to get out of bed. Weight gain, obviously. minor itching. It has helped my anxiety and depression. I am beginning to take half a pill and that has reduced the symptoms. F 59 3 weeks
10 mg 1X day
12/16/2014
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 3  Major Depressive Disorder/bi polar Has helped with overall daily depressive state, but if I get upset, it's like the world is ending - except that I wouldn't even care. Anxiety/OCD seems to be worsening now that I'm at three months. Have an irritable disposition anyway, but now worse, sometimes very bad. (also take lamictil for 3 years now). Unsure what I'm going to do w/the med moving forward. F 43 3 months
10 1X day
12/9/2014
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 3  Major Depressive Disorder Worsening Anxiety Brintellix helped me get out of bed, but over time made my anxiety worse. Upped to 10mg after 3 mths. But dropped back to 5mg. Due to anxiety. Just went off of it a few days ago. F 43 4 months
5 1X day
12/6/2014
 2  For Depression Itching, sudden outburst of crying and a total feeling of tiredness. Lack of energy. F 50 14 days
10 MG 1X day
12/1/2014
 1  anxiety Did not help anxiety at all...actually made it worse...on day 10 had my first true panic attack ever...felt like I was dying...have not taken it since. This medication did help very much with irritability I felt toward people and I was very disappointed that the anxiety worsening caused me to discontinue it. F 57 10 days
10 mg
12/1/2014

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