TRINTELLIX Reviews (VORTIOXETINE HYDROBROMIDE)

Average Rating: 2.8 (306 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

BRINTELLIX  (VORTIOXETINE HYDROBROMIDE):  This medication is used to treat depression. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Vortioxetine is an SSRI (selective serotonin reuptake inhibitor) and serotonin receptor modulator. This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.   FDA Approval Date: 2013-09-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR TRINTELLIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Major depressive disorder Muscle aches, headaches, runny nose, feeling flat, decreased motivation, nightmares, itching, diminished sex drive I no longer feel suicidal but the side effects are too much. Tapering off now and feel like I have a mild case of the flu. F 40 7 weeks
10 mg
7/5/2016
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 1  Severe anxiety & depression I couldnt lose weight, gained slightly, and was so incredibly edgy. I felt constant anger, anxiety and self-hatred. After trying about 6 different meds to treat my anxiety and depression, i despised this one the most. I fought with family constantly and couldnt control my emotions AT ALL. And felt more depressed because i started gaining weight. I would recommend you stay as far away from this medication as possible. F 20 3 months
30
7/3/2016
 3   Upset stomach M 58 2 months
1,0
7/1/2016
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 3  generalized anxiety and depression dizziness and nausea Disorder, generalized anxiety and major depression. After three months failed treatment with escitalopram 20 mg and 3.5 mg lorazepam specialist values ​​change to vortioxetina (brintellix) starting with 10 mg, the first days mild side effects with dizziness and nausea. After three weeks of treatment with no apparent improvement in my state the specialist assesses the dose up to 15 mg not noticing significant improvement till the ninth week of treatment with brintellix. The most appreciable it has been on my anxiety disorder improvement not so much in what refers to depression although this also appreciate a slight improvement though still modest. Discomfort as anhedonia and tiredness even though I continue to notice some improvement at the cognitive level. Also appreciably increased appetite although without gaining weight. Currently I have managed to lower the dose of 3.5 mg lorazepam 2.5 mg thanks to lower my anxiety levels. waiting next valuation specialist to continue giving an opportunity to brintellix. regards M 40 9 weeks
15 mg
6/27/2016
 5  Anxiety/severe panic attacks Intermittent Dizziness. Annoying,but tolerable. Anxiety went from a 9 to a 1.5-2. Very very satisfied. Best medication for panic and GAD, in my opinion. Took effectorXR for 7 yrs and this year anxiety was the worst it's ever been. Brintellix saved my life. F 35 6 months
10mg
6/23/2016
 5  Anxiety Little dizziness first few months, but that is also a side effect of anxiety. Took about 7 different medicines for anxiety two of them I ended up in hospital over them, brintellix was my last hope.And it has worked wonders for me. F 61 2 years
10
6/23/2016
 3  Depression & anxiety Horrible nausea, rapid weight gain. It helped, tremendously, with the anxiety. F 38 3 months
10mg
6/23/2016
 1  Depression and Anxiety Terrible weight gain F 39 2 weeks
10mg
6/22/2016
 1  Manic depression Migraine headaches very bad. Itching and severe nausea then vomiting so no appetite. Want to stay in bed terrible drug Waiting for doctor return call to hopefully get off this F 59 3 days
20
6/9/2016
 4  PTSD, MDD, PANIC ATTACKS, GAD I tried this med last year but due to extreme constipation switched. Back on it now because other than constipation it's the best I have ever tried. Since I was on 40mg Prozac 2 weeks ago and could not wean before starting brintellix I am only on 5mg right now. Prozac can take several weeks to leave the body and increase brintellix effects by 2 times. When I try to increase my dosage right now I have symptoms of serotonin syndrome for about 1 hour (heart racing, sweating, shaking, shivering, anxiety, nausea), so I am waiting another week to increase to maybe 7.5. Cutting the pills is difficult (shape), but it can be done. First few days I experienced a metal taste in my mouth, feeling of warmness, and a little bit of jitters about 1 hour after taking it. Only lasted 5 to 10 minutes. Now I have night sweats, feel little motivation, and sleepy, but it has helped with my anxiety a lot. Anxiety feels physical so I don't freak out. Last time I was on 10mg I felt pretty good all around. Feel more logical and in charge of my life, less emotional and out of control. I'm expecting to feel better as I will slowly increase to 10mg over the next few weeks. Do not recommend transitioning from Prozac because of long half life and increase of brintellix plasma makes transitioning extremely difficult. Other side effects right now are sometimes upset stomach, soft stools, little moodiness. F 46 2 weeks
5mg
6/3/2016
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 5  Mdd No major side effects. Seem more on an even keel. Helps with my anxiety. Had fewer panic attacks. F 44 8 months
5/27/2016
 1  Major depression Paranoia, agitation, thought people were plotting to kill me. Extreme anxiety. Feeling of "losing it". F 47 45 days
10mg 1X day
5/21/2016
 5   A little nasuea after a couple of days but gone within the first week Thinking clearly and feeling great! Anxiety issues are gone as well. M 44 6 days
10 MG
5/19/2016
 4  MDD(major depressive disorder) Anxiousness, I have to take sleeping pills to sleep otherwise id be up all night restless. This medicine is GREAT for major extreme depression, like I can't move or get out of bed depression. It gives you energy, motivation, but too much of it can make you feel kind of just Ughh blah ya know. So stick with the dose whatever makes you happy and have energy. Brintellix is the boss over any ssri out there. M 24 4 weeks
10
5/17/2016
 2  Depression Strange neurological symptoms I had heard great things about Brintellix so I was excited to try it and was extremely disappointed when I had an adverse reaction. My face went numb, lips tingly, I was slurring my words, and my whole body was twitching. It was some kind of strange migraine/seizure-like neurological thing so I had to stop taking the med. Luckily none of the bad effects lingered after the Brintellix was out of my system. F 22 3 days
5 mg
5/17/2016
 5  Depression/Anxiety/Toxicomania Visual hallucinations, nausea, morning insomnia (wake up at 5 am but refreshed), dizziness, irritability. Side effects are mild and subsides after 1 week. Better tolerance, than with tricyclics and SSRIs/SSNRIs. Brintellix is a serotonin modulator and stimulator that has a different mode of action and also stimulates norepinephrine and acétylcholine release in the brain. I was a methamphetamine drug addict, and I tried all the antidepressants available including tricyclics. Anafranil was excellent but I had some annoying side effects. Since I take Brintellix, the brain fog disappeared and I have more energy, more motivation, a better quality of life and I don't suffer from social anxiety anymore. My quality of sleep is better. I didn't gain any weight. I have a more concentration and it helps my ADHD. I use in combination with Vyvanse 40 mg, Lamictal 100 mg and Wellbutrin SR 100 mg BID. People that didn't try for at least 4 to 8 weeks shouldn't put ratings on drugs. M 37 2 weeks
10 1X day
5/16/2016
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 5  Depression Jaw clenching! It has been fantastic for me. I've had no serious side effects such as nausea, diarrhea etc. I feel more focused and on top of things. F 52 6 months
10 1X day
5/15/2016
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 3  Major Depressive Disorder hyper anxiety, nausea with coffee, compulsive eating, unusual dreams, i do think it has helped the depression, but has kicked the anxiety into overdrive. F 44 2 months
10MG
5/11/2016
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 3  Major Depressive Disorder First couple of days on this medication I was knocked on my butt. Very fuzzy, tired and dizzy. I definitely experience nausea on this medication but nothing I cannot handle by now. If I do not eat with it, that's when I experience most of the nausea. Also, if I do not eat with it I will experience diarrhea. I have a great doc who put me on the brat diet until the symptoms were tolerable. Organic apple juice, toast, rice, crackers and light chicken soups. Other than that, I have not had anything bothersome other than insomnia which I take benedryl to help relieve. I'm very sensitive when it comes to medication. So instead of switching me, my doctor helped me work my way through the side effects. 10 mg pulled me out of a depressed fog. I suspect I'll end up on 20 mg for full relief. No high blood pressure, no weight gain, no food cravings....it's worth a shot if you can get through the first few weeks. F 36 3 weeks
10 mg
5/11/2016
 5  Major Depressive Disorder Decreased sex drive (as with all antidepressants I've taken) Brintellix cured me of MDD. I have been on antidepressants for 7 years and this is the only medication that helped me. I was on Celexa, Zoloft, and Effexor before I took this and the previous medications all failed. I took Brintellix for 2 years and I'm now in my final days of weaning off the medication. F 25 2 years
10mg 1X day
5/4/2016

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