TRINTELLIX Reviews (VORTIOXETINE HYDROBROMIDE)

Average Rating: 2.8 (306 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

BRINTELLIX  (VORTIOXETINE HYDROBROMIDE):  This medication is used to treat depression. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Vortioxetine is an SSRI (selective serotonin reuptake inhibitor) and serotonin receptor modulator. This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.   FDA Approval Date: 2013-09-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR TRINTELLIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Depression No motivation Pure crap 44 6 weeks
15
2/21/2018
 2  MMD ptsd Headaches feeling sick no energy sexual dysfunction uncontrollable appetite weight gain brain fog no motivation Helped depression F 57 3 months
5 10 15 1X day
1/8/2018
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 1  Depression Pancreatitis I had previously given Trintellix a rave review on another site. Since that time, I have been suffering with pancreatitis, which the doctors could only attribute to Trintellix, as I had no other contributing factors, AND pancreatitis is a known side effect of the drug. Trust me - you NEVER want pancreatitis! This is something you would only wish on your worst enemies. From now on I will look at the side effects of every medication before even trying them. F 47 2 years
5 mg 1X day
1/8/2018
 5  Clinical depression Nausea in the beginning even on the 5 mg. As I have continued some days the ankles swell. Doctor recommended compression knee highs; which work when I wear them. The itching can get aggravating some days (1-3 x a week). I use a benedryl spray. It stops the itch of my R thumb, R knee, both forearms ( only itchy in 1 place at a time). Depression seems to be gone completely. Considering talking to doctor about 5 mg a day. Previous meds in order since 1996: Effexor (gained 90# in 7 mos.!!!); Wellbutrin(wonderful and stopped for awhile); Cymbalta (long term, low dose); then Abilify (run from this!) with Cymbalta(these 2 for 7 months b4 Trintellix). Trintellix is expensive; yet I have good health insurance coverage. I pay a higher co-pay for this drug. Will stay on this until I think I am past depression...with consultation with doctor. I wonder how to get brain to produce enough serotonin after 21 years in low doses of anti-depressants. Puzzled. F 71 2 years
10 mg
12/5/2017
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 4  Anxiety and depression Starting out on the medication :Nausea, headaches, dizzy spells. During: lower libido, plateau of emotions. Decreased creativity and drive. Coming off the medication: hot flushes, insomnia, panic attacks, acid reflux, very oily then very dry skin fluctuations. Off the medication: Suffering from very bad Acid reflux due to the prolonged usage of the medication. Brintellix helped me over the 4 years I took it but if I had known about the severity of the side effects I would have thought twice about taking it. F 26 4 years
10
10/6/2017
 5  Depression and A lot of Anxiety Nothing really but I have had a really sore lower back. I didn't think anything of it until I looked up the side effects just to see what people have encountered. Honestly this has been the easiest and best anti-depressant I have ever taken. No headaches, no nausea, no increase in hunger, no decrease in libido. Nothing but a sore back that has gone away. I am really happy and surprised how much this has helped me with my intense anxiety and depression. It has helped out majorly and I am glad I am taking it. Everyone is different, but I think majority of people don't leave a review if they have nothing to complain about. This has been a life saver, thank you doctors! F 37 2 weeks
10mg 1X day
9/18/2017
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 3  depression mild nausea, diarrhea, fatigue, feeling achy, neck stiffness, jaw cramping, and shakiness. Also lost ten pounds.. worked great for the depression, but I am physically too sick to carry on my normal activities. Am going to quit taking and see my psychiatrist this coming week. If no relief of symptoms will go to gastro doc, as my regular physician suggested. F 70 2 months
10mg 1X day
7/30/2017
 1  Anxiety & depression Mine is called Trintellix I have been taking 5 mg for 13 days and week two had terrible neck pain couldn't even turn my head it hurt so much aching all over in the am. Also got a migraine headache with a bad sore throat and stomach pain bye-bye Trintellix calling my doctor tomorrow made me feel worse than ever so tired too F 61 13 days
5
7/23/2017
 1  Major depression Major nausea, fatigue, dizziness, itchiness, burping, sleepiness, rage. This drug made me so sick I couldn't stay on it, and I tried for just over a week and a half. It made my depression worse, I itched all over, the nausea was so bad I threw up. I can usually handle side effects ok, but not on this poison. My doctor said most of her patients had bad reactions to it and won't prescribe it anymore. Stay away. F 37 2 weeks
7/1/2017
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 4  Anxiety and depression I felt amazing and tons of energy and enjoyed life to the max. The only horrible thing was I couldn't sleep at night. F 65 3 days
5 1X day
6/24/2017
 2  depression, anxiety, ED nausea for first few days (could barely eat), elevated mood and optimism followed by worsened mood, felt stoned, cotton in ears, felt numb, emotional flattening, decreased libido Decided to go off it rather than wait out the side effects due to high cost of the drug. F 28 8 days
? 1X day
6/21/2017
 1  Anxiety Generalized itching is making me crazy! Can't even sleep I'm so itchy Stopping immediately even if bad effects from it F 57 6 days
5 mg
6/8/2017
 2  Anxiety and depression Strange dreams Indigestion Aggitation Crying Vomiting Diarrhea I was worse on it than off it F 41 1 months
5/28/2017
 2  Severe Depression and Anxiety Nausea and taste changed. (Made a lot of things I normally eat/drink sweet.) I started on 5 MG for two weeks, everything was fine, moved up to 10 afterwards, I still get depressed, but other than that, the only good thing this has done for me is helped me lose weight according to other people. F 19 4 weeks
10 MG 1X day
5/6/2017
 4  Depression Started on 5mg for 1 week with no side effects and felt my depression lift significantly. Upped the dose to 10 mg per my doctor's orders and experienced horrific nausea and stomach pain for a week. Called Dr and was advised to go back to 5mg and have done so for the last two days and so far no nausea and mood is improved. Will stay on 5mg for a longer period of time as there may not be the need to go any higher. F 60 3 weeks
5mg
4/19/2017
 1  Anxiety Made me impotent the first week of taking it, upon which there has been no remission of this side effect. I am still impotent. It's as if it switched off something in my brain. Absolutely be very careful if you take this medication. Horrible drug. M 32 3 months
5
4/8/2017
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 5  Major depressive disorder and anxie I was first on trenilix but men should not use it so when over to brintellix 5mg for 6 days on the 7th day 10mg when I was on 5mg it works amazing for me but when o took 10mg today I thought I'm going to die stomach pains felt nauseous dizzy and had a hot fever I'm not quiting brintellix just going back to 5mg where I feel safe I could even smell chemicals of brintellix in my nose 10mg is not meant for me It's work just get the right dosage for you start low and then move up in mg if need be but I'm still only in my second week but besides what happen today this stuff works M 32 2 weeks
10mg
3/14/2017
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 5  Major depressive disorder and anxie I was first on trenilix but men should not use it so when over to brintellix 5mg for 6 days on the 7th day 10mg when I was on 5mg it works amazing for me but when o took 10mg today I thought I'm going to die stomach pains felt nauseous dizzy and had a hot fever I'm not quiting brintellix just going back to 5mg where I feel safe I could even smell chemicals of brintellix in my nose 10mg is not meant for me It's work just get the right dosage for you start low and then move up in mg if need be but I'm still only in my second week but besides what happen today this stuff works M 32 2 weeks
10mg
3/14/2017
Email
 5  Depresja, stany lękowe Lekkie nudności,poczatkowo brak apetytu, dziwne sny Lek cud! Szybko zadzialal.Uspokojenie,wyciszenie bez stepienia emocji i uczucia sennosci,ogólnego zmeczenia.Nie zaburza libido.Szybka poprawa samopoczucia. F 40 10 days
10 mg
3/11/2017
 3  Clinical depression & anxiety Itching, slight nausea, headaches and dizziness I started Brintellix after a non-responsive treatment on lexapro, After 1 week I was feeling extremely overwhelmed by things that wouldn't usually phase me, very depressed and anxious. In week two I was feeling so down I resorted to drinking (which I hadn't done in months) and self harmed whilst hysterically crying all night, this was the lowest point I had felt on the medication. Coming into week three i'm feeling extremely optimistic about life, I have more energy and am able to focus well on work. I read ample reviews on this drug when I first started this medication and spent hours on this site tossing up if it were the right thing for me. I think sticking through the rough patch was the best thing I did.. It's still early days but after time things are becoming clear again and i'm starting to feel as though i'm not stuck in a hole with no way out. Fingers crossed it stays this way and everyone else has a similar experience going forward! F 22 3 weeks
10 1X day
3/6/2017

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