TRINTELLIX Reviews (VORTIOXETINE HYDROBROMIDE)

Average Rating: 2.8 (306 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

BRINTELLIX  (VORTIOXETINE HYDROBROMIDE):  This medication is used to treat depression. It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Vortioxetine is an SSRI (selective serotonin reuptake inhibitor) and serotonin receptor modulator. This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living.   FDA Approval Date: 2013-09-30 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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  Charts & graphs: Drug Safety Information

RATING  REASONSIDE EFFECTS FOR TRINTELLIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Major Depression So far I'm really liking it, and I've had them all. I happened to see a leaflet on it in the doctor's waiting room, luckily. Hopeful. F 55 5 days
10 mg 1X day
5/3/2015
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 3  depression after being on zoloft for several years, I experienced some catastrophic events and needed a boost. My doctor recommended trying Brintellix. I eventually was up to the max dose of 20mg daily and began feeling unusually numb. I dropped down to 10mg and ever since then I have had terrible bouts between anxiety and full blown paranoia. I just saw my doctor today and made the switch back to zoloft. I will add that the brintellix did help with depression but I never felt like myself on it. F 28 6 months
10mg
5/2/2015
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 4  Major Depressive Disorder I didn't experience any side effects except for weight loss. It decreased my appetite I've been on every antidepressant out there. The thing I like the best about it is that it doesn't give me any feeling of grogginess or balloon head. Best one, by far, that I've ever been on. F 51 4 months
10 mg 1X day
5/1/2015
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 1  anxiety Horrible nausea, vomiting, headache, and panicking. Allergic reaction suspected. Nausea still present weeks later. F 57 1 weeks
20 mg
4/24/2015
 3  Depression Depression relieved, yet having low libido. Not sure if it's from the med or due to hormones. F 46 6 months
20 mg 1X day
4/21/2015
 3   1 days
4/19/2015
 5  MDD, GAD Nausea for the first few weeks and a few dizzy spells I am from Canada and take Trintellix, I was recently hospitalized due to suicidal thoughts, major depression and severe anxiety. 3 weeks into this medication I am laughing, smiling, SO much more energy and negative thinking has subsided completely. Have hope for the future now. This medicine saved my life. If your scared to try it, please don't be. I'm medicine phobic but i probably wouldn't be here today if it was not for trintellix. Looking forward to more positive results as it takes 3 months to Take full effect. Also on 2mg Ativan daily. F 28 3 weeks
10
4/18/2015
Email
 5  Major depression Increased sex drive, occasional nausea. Then I became pregnant....after 5 months of vomiting day and night, I realized the brintellix mixed with my hormones made me terribly sick. The same day I cold turkey stopped the Brintellix, I haven't vomited since I am very sad and disappointed i had to stop the Brintellix because I have tried very single depression med out there and this was the only one that worked with minimal side effects and added bonus of increased sex drive. I plan on going back on it as soon as I have the baby. I didn't experience any of the itching or head aches others have referred to F 31 9 months
20mg
4/17/2015
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 5  Effexor stopped working for my depr Nausea and vomiting...severe. Diarrhoea I'd use it any time and definitely recommend it even with the severe nausea and vomiting. My mood has lifted and I have a cognitive brightness. I laugh more and am completely anxiety free F 41 1 months
20mg 1X day
4/15/2015
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 4  MDD Loss of sex drive. Gained weight. It takes time for it to start working. Within a few weeks I was feeling better. Within a month I was feeling a lot better. At 3 months I feel like a normal person again. I don't cry all the time anymore and I sleep appropriately again. F 38 3 months
20 1X day
4/1/2015
 3  Mdd Nausea the first day, fatigue (but I have fms/cfs so..), moderate irrability in the afternoon before my dose is due, headaches I still cry. Just not as much. I'm still toying with the idea of suicide, just not as much. I've been able to fake happy better. I'm not weeping uncontrollably for hours on end. There's some light tremors, or shakiness in my hands. I've been kind of spaced out. Driving is not going smoothly, I'm a danger out there, no ability to judge distance & im easily distracted. But im tolerating it better than any other antidepressant ever tried. No hypomania, no rocking involuntary back & forth or pacing or tapping my toes or rubbing my fingers together, no intense desire to kill myself (that wasn't already there), no weight gain, no lack of sex drive or inability to orgasam. So far, it's ok. Am trirating up soon, that's where all the real fun begins, so I'll report back then F 39 8 days
5mg 1X day
3/27/2015
 5  Major Depression Moderate to severe nausea lasting 6-8 hours each day. I was on Celexa for over 10 years but eventually it lost it's efficacy with me. I switched to Brintellix with no adverse effects during the transition. Within the first 2 weeks, my husband first began to notice how much more I was laughing and smiling., I have increased energy and feel better than I have in years. F 50 5 weeks
10 mg 1X day
3/24/2015
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 4  MDD, anxiety Horrible nausea at first; usual SSRI sexual side-effects. No weight gain. Was switched to this after 10 yrs on Cymbalta (pooped out). Horrible nausea at first and still on occasion. RX'ed Zofran to offset and it helps a lot. Not a panacea (what is?), but I'm out of the "hole." Not as tired as I ALWAYS was on Cymbalta, which is great. No weight gain. F 49 4 months
20 mg 1X day
3/22/2015
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 4  MDD Mild headache, Extreme Sex Drive Increase, Mild Nausea Took this after taking viibryd for a year. It was such a relief to not have brain zaps anymore. I went from having no sex drive to wanting to hump everything in sight. Has helped me a lot. F 21 8 months
10 mg
3/21/2015
 2  Depression vivid, unpleasant dreams, even weeks after use was discontinued This drug gave me a little bit of energy during the day but was largely useless when it came to treating my depression. M 32 8 weeks
10mg/d
3/14/2015
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 2  depression and anxiety Intense itching for first two weeks, which subsided, but returned after about 7 months. My face and scalp itched so intensely I literally scratched the blood out of my skin. AND my hair began to fall out in large clumps. Took about six weeks after stopping Brintellix for the itching and hair loss to stop. I would NEVER take this drug. Benadryl did nothing for the itching. Worked great for both depression and anxiety, I felt so much better that I tried desperately to continue taking it in spite of the itching, but could not bear for all my hair to fall out too! Side effects were worse than the MDD and anxiety. F 59 8 months
20mg 1X day
3/9/2015
 4  anxiety and depression The first day I took this medicine, I felt just kind of a blah feeling, but after that I have not had any major side effects except for a few bearable ones. I have had a sleepy ,calm feeling. I think that this is what this medicine is suppose to do to help relax and wire me down. I am able to fall asleep without over thinking so much or even thinking random, ongoing thoughts.I have had a little bit of itching in different places,but nothing that is unbearable. I have noticed yesterday that when I wanted to cry,it was hard to . I would get a little sad, but I couldn't just bust in tears like usual,or even shed tears. I have also had small headaches here and there,but again,nothing unbearable. My mood I feel is a bit better. I'm a little brighter and more calm, but I also feel that I haven't been on it long enough to feel the full affect. I was so scared to try this because of side affects ,but I have been blessed to not feel anything horrible. I feel that this medicine will be a success in the long run. :) F 22 9 days
5mg
3/6/2015
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 5  Depression Limited nausea at first. Started taking it before bed and don't have the symptoms any more. Generally I am quite happy with product. I am a long term user of other anti-depressants and this one has fewer side effects. I still am a bit down some of the time and wonder if a higher dose like 30 mg would do the trick. I enjoy not being constantly sleepy like I was with Lexapro et el. M 58 6 months
20 1X day
3/1/2015
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 4  Depression, anxiety None No effect yet! M 39 4 weeks
10 mg
3/1/2015
 2  bipolar manic depression, anxiety Extreme dizziness, nausea, muscle weakness, back of neck stiff and tight, pain behind eyes, non stop diarrhea, made acid reflux worse, made anxiety worse I am a veteran when it comes to psychiatric medications. Due to poor care over the years, I've become med resistant which is scary and overwhelming. Please remember that everyone responds to these medications different. Also keep in mind when you are doing research that these medications take at least 30+ days to get in your system. I tried to battle out the side effects and today made the decision that the bad outweighs the good. The dizziness and muscle fatigue was terrible for me. The nausea was getting better and I found that taking it at night helped. I noticed that it killed my sex drive but oddly I had some of the best orgasams. Weird! I also felt like this med was trying to work but would fade followed by extreme anxiety. I also take depakote, adderall, ativan and saphris to sleep. After 2 months and still scary low, I'm considering going off. My Dr bumped me up to 10 mg yesterday but I'm finding it hard to come up with the fight to continue a med that causes me so many side effects. Best of luck to everyone in search for their right combination. F 37 2 months
10mg
2/27/2015
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