ENBREL Reviews

Average Rating: 3.7 (525 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug
  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  PsA Injection site reaction. (Red welt that lasted a few days) slight headache day of injection. Felt it worked with my joints, but not so much for the psoriasis. F 44 7 months
11/15/2021
Email
 5   Weight gain, thinning hair, occasional bruising at injection site. I could not walk across the floor without the bottom of my feet throbbing and I kept my thumb in a splint so nothing would touch it. I just knew my RA was making me wheel chair bound. Enbrel changed my life! I have the occasional flare up for a few days along with stiff back and hips. But I mow my lawn, walk all day showing properties, get in the floor with my grandkids, chase my dog. I have a happy and productive life. Enbrel gives me energy for several days. I feel great for 4 or 5 days. But I can tell when it's time for my shot. I'll take thin hair and some weight gain for a productive life with much less pain. F 60 4 years
50 MG 1X W
11/14/2021
Email
 2  Rhumatoid arthritis Was stopped after developed lung nodule F 51 6 weeks
125mg 1X D
10/4/2021
Email
 2  Psy arthriris Tired. M 53 7 days
50 1X W
9/15/2021
 4  RA Just started Enbrel. Very fatigued post injection for a few days with increased hand stiffness, swelling and joint pain. Then it seems these symptoms fade and I feel better until time for next injection. No pain with injection or site reaction. I've been on many other meds for RA/ overlap syndrome and it seems they all have a " break in"Ě period before the true effectiveness is felt. F 53 2 weeks
1X W
2/24/2021
 4  RA Hair loss not out of all pain but helped lower my vectors score F 59 4 years
50mg
12/4/2019
 4  Ankylosing Spondylitis Helped the sacroiliac pain. Con: Weight gain F 52 3 years
50mg
11/27/2019
 2  Psoriatic arthritis It first started off with the injection site was itchy, red and swollen for days.... that was the first 2 weeks 3rd week my body is covered in a BAD rash all over!! Is been 1 1/2 weeks !! Iím still covered... itís awful F 55 28 days
60
11/7/2019
 5  RA of 100% full skeletal frame, Fib Minor itching and bruising on injection site. Did not experience any side effects. Flare ups are less, if I do get them it's not debilitating, not stiff in mornings, way of life improved dramatically. Humira did not compare with how fast Enbrel worked on my issues. Not able to move for hours on upon waking up in the morning, to being able to get up and roll out of bed with no issues. I still have inflammation and pain, but Enbrel gave me back some quality living in my life. I also have Fibromyalgia which affects 100% of my muscle in my body. I started being sick when I turned 48. F 57 7 years
50mg/ml
7/11/2019
 5  RA Itching bruising at injection site, 3 days or more Couldn't live without it, the pain in my hands and feet are all but gone. I am still tired and depressed most of the time, but the pain is gone. F 57 6 years
50 mg
6/4/2019
 2  PsA Even more fatigue than I already had. Then I started getting rashes that seemed to thicken. I went to the dermatologist and she couldnít really explain it but gave me some ointment for it. I also started getting headaches which I hadnít had for 20 years. It got to the point at the end of the day were the only energy I had left I had to decide whether to brush my teeth or wash my face. Brushing teeth always comes out on top. I felt a little better like the first month and then it just drastically has gotten worse. Oh yes and the restless legs the knots in my calf muscles are the worst. I never understood what people were talking about that had restless legs. Now I know and they keep you up for hours on end at night. I took my last shot last Friday and Iíll never go on it again. 58 0 months
40mg
2/13/2019
 5   Very slight skin dry spots I have been injecting for 15 years, it was a complete game changer for me was close to being unable to work, but have been in employment the whole duration, was one of the first to be prescribed, Iíve been asked by my rhumetologist if I would like to go back to methotrexate but the thought fills me with trepidation. M 55 15 years
50mg
10/17/2018
Email
 4  PSA fatigue, mild common cold like symptoms I took my 2nd injection on Wednesday. It seems like it has instantly helped my scalp rash. My low back pain has started to get better. However, I am SO tired. I could sleep all day if someone let me. I'm hoping this wears off as it is only my 2nd injection but time will tell. I also have a bit of a cough and some cold like symptoms. They aren't bad, the fatigue is the worst part. I have taken Plaquenil, Methotrexate, Sulfasalazine and maybe some others and so far this is the only one that I have not yet had something worse happen like increased rash, vomiting, hair loss, etc. I'm willing to give this some more time. F 36 2 weeks
1X W
8/25/2018
 4  RA I have a severe rash on my body. Worst is in groin area and under breasts. Seems to be in areas that I sweat. Could this be a side affedt of Enbrel? F 53 0 weeks
1/7/2018
Email
 2  RA/Severe/Seropositive Developed shingles which is not necessarily a ďside effectĒ except that it brought my immune system down so low that is what caused them! Was SO lucky to only have a small spot on my back and caught it early! No other real side effects, just didnít do ANYTHING:( for the RA, joint pain, fever, and fatigue either :( Donít know if it makes a different or not? But I had EXTREMELY SEVERE chicken pox when I was small! Was hospitalized and still have a couple scars from them. But Xeljanz is know to cause shingles too and I didnít get them when I tried it?! Just giving info I hope can help someone else out there! Good luck on your med search! :) F 38 3 months
12/15/2017
Email
 5  Psoriatic Arthritis Mild injection site reaction Amazing, immediate results after one injection; alleviated all pain and kept the progression of my disease in check for 14 years. VERY pleased with Enbrel - gave me my life back. Not sure why, may have been linked to hormone changes brought on by menopause, (?) but I began to have pain, stiffness and swelling in my finger/hand/wrist, along with pain in feet, stiffness upon waking all over, back and neck pain. Rheumatologist switched me to Humira with no change, added Arava - been on this for a month with little to no change. F 47 14 years
50 MG 1X W
10/31/2017
 1  Ra Developed lock jaw two hours after First injection which lasted four days.after 24 hrs developed the worst sore throat that put me in the hospital could barely breath throat closed up.now one week after really scared to repeat.rhmatologist has taken me off so back on Prednisone again now going on four years.to anyone with this disease you have my admiration for keeping going as sometimes this can be all consuming and mentally crippling as well. I have read the success stories and God bless all who this drug has helped.it just wasn't me.thank my wife who has gone through hell keeping thing going through the last four years. M 63 1 days
50
10/11/2017
Email
 3  Psoriatic arthritis After 1 or 2 injections, I had sinus issues, gurgling in my chest when I would breathe in and out. I started losing hair but didn't put 2 and 2 together until I had lost a great deal of hair. I did not want to stop taking enbrel because I felt so much better! My joints were 85% better. I just kept losing more and more hair. I made the decision to stop enbrel. It has been 1 week without it and I am in severe pain again. My sinuses have cleared, the gurgling is almost gone. I'm still losing hair but praying that will stop soon. I'm very tempted to start taking enbrel again. I pray for all who are in pain! F 52 6 weeks
50mg 1X W
9/21/2017
Email
 3  RA Loss of hair, bad infections,severe headaches.But, it stops that pain in it's track.I started 10 yrs.ago & really just finding out about all these nasty side effects.Stop myself from taking it 3 yrs. ago, just got back on last yr.I'm mad as he'll bout my hair, been buying hair for yrs.I forgot about the stomach pain. Don't know what I'm going 2 do for pain. F 63 10 days
50mg
8/31/2017
 5  Rhemotioud Upset stomach for a couple of days a week. Can move my hands after 20 years. Improvement after 1 week . F 54 3 months
50 1X W
5/6/2017
  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.   (Sources: U.S. Centers for Medicare Services, FDA)

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