ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  RA Had every side effect there was except for cancer. Was a very bad drug for me! F 45 6 weeks
50mg 1X W
3/5/2011
 5  Severe Plaque Psoriasis Slight fatigue, minor nasal irritation. I had severe plaque psoriasis over 20% of my body for about 15 years. After three months of Enbrel x2 week injections it was 99% cleared up. M 50 5 months
50mg 2X W
3/3/2011
Email
 3  Ankylosine spondylitis Have not been on this yet .My Rhumy wants me to start it as my as is rather severe at this time in my ribcage,sternum and is effecting my breathing..After reading about the side effects i am rather terrified to do so.Would really appreciate any feed back. M 40 0 days
1X day
3/2/2011
Email
 3  Rheumatoid Arthritis Dizziness, pain at injection site, headache Worked well for me for about 6 months then all my symptoms came back. Tried twice weekly injections and that worked for a few months but eventually I switched to Remicade. Worked well for 6 months! M 38 10 months
25mg 1X W
3/2/2011
 3  Psoriasis/Psoriatic Arthritis Had no side effects at all. Have had Psoriasis for 18 months. It covers my legs from the knees down. The injections were almost painless if I let the sureclick pen set out @ 25 minutes before using. I was so excited to use this especially after 1st injection. It gave me energy within 4 hours and took care of all my joint pain. Unfortunately it did nothing for my Psoriasis : ((. I am about to begin Humira and pray it helps or I'll be wearing pants this summer - bummer!! F 42 3 months
50mg 1X W
2/22/2011
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 1  RA Intestinal pain, severe very frequent diarrhea, stomach cramping I was diagnosed with severe RA 20 years ago. Among the meds I have taken are methotrexate for 2 years, sulfasalazine, prednisone, planquinil, leflonomide and other RA drugs. I took the first Enbrel autoinject on Nov 30,2010 developed severe diarrhea with stomach and intestinal cramping on Dec 24, stopped Enbrel on Dec 28. Almost two months later, I still have loose bowels, intestinal and stomach pain, but the diarrhea is no longer explosive and is usually restricted to between 5am and 9 am; frequency is about 6 bowel movements. I am no longer able to eat the foods I ate before such as raw vegetables, spices and chocolate. Before Enbrel, I was very regular with normal bm's and I could eat anything without causing stomach problems. I am now worried that this may be a long term or permanent effect. Has anyone else experienced this? If yes, did you come across anything to alleviate it? Other from this I had no other immediate side effects but recently I noticed red spots on my forearm. I also seem to have more sinus congestion. I don't think enough is known about this drug and I don't recommend it. F 63 5 weeks
50mg 1X W
2/21/2011
Email
 1  RA nausea; eventually side effects include cancer and MS. Note if you send me a message provide your e-mail address or I cannot respond the drugs will poison you; try the honey and vinegar diet which cured me and vitamins! (esp niacinamide) See for instance Dr Saul's website at doctoryourself.com or his book Fire Your Doctor. Everything is curable, 'just say no to drugs'. (Nancy Reagan) 55 30 days
50 mg 1X W
2/3/2011
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Patient History
 5  juvenile rheumatoid arthritis This drug has shut down my daughters JRA. She is able to run, jump, dance, play the piano, even do a back bend. F 8 3 years
25mg 1X W
1/18/2011
 5  RA Best thing my rheumatologist ever did for me! M 50 6 months
50 mg 1X W
1/12/2011
 5  Psoriasis, Psoriatic arthritis None. AMAZING! Had been on 15 mg Methotrexate a week for about 4 months, then 3000 mg Sulfasalazine a day for 3 months, both of which done nothing to help me. Was needing to get fluid removed from my knee every other week, around 120 ml at a time. Was told by a surgeon that the only thing that was going to help, would be to have an operation to remove the lining of my knee. Then was given Enbrel, and within a week could see a difference! Was able to walk without crutches, and be able to do things on my own again. Would recommend it to anyone. F 22 4 months
50 MG 1X W
1/8/2011
 5  RA A little stomach pain. Been taking Enbrel for 8 years.Would not be able to work if it were not for this drug. I could not even get out of the bed some days. I started taking 25mg 2 x a week now I take 25mg once every 2 weeks. I also take alot of natural remedies. F 54 8 years
25mg 2X M
1/7/2011
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 4  RA I seem to be more prone to headaches now and they're accompanied by nausea and vomiting; however, they could be caused by a combination of the drugs I'm taking plus environmental toxins because I don't always get them. F 59 4 weeks
50 MG 1X W
1/5/2011
Email
 4  Psoriatic Arthritis So far so good...haven't had any side affects It has helped alot with my psoriasis but I can't say that I have noticed a difference with my arthritis. I got to the Dr. next month and I guess I will see from the results of my blood work if it has helped. I find that if I leave it out for 30 minutes it doesn't hurt when it is injected and I also inject in in the inner thigh and not on the top and that seems to be less painful also. F 42 3 months
50mg 1X W
1/2/2011
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 4  RA Weight gain (20 lbs since start), Sinus drain, heavy mucus in throat, hot flashes (only 41 yrs old), very heavy & long menstrual cycle, developed asthma & over 20 allergies, fatigued day after injection, bruise on legs and arms very easily, hair loss. I am Canadian and have been taking Enbrel for almost 10 months now. I have had severe RA for almost 8 years and tried everything before being approved for Enbrel. The difference in my RA before Enbrel and now is astonishing. I can use my hands again and joints no longer locked, I walk pain free 8/10 days. 10 months ago I was so depressed from the constant pain every day. I never had a day where at least 5 joints were not swollen and inflamed. My children had to get me dressed, do my hair, and help we walk. No longer. The side effects so far have been more bothersome than anything and with the exception of the asthma & mentrual issues they have been easy to deal with. I would not change if I had a choice. F 41 9 months
50MG 1X W
12/19/2010
Email
 4  PPP and PA I get headaches, pain at the injection site, dizziness and noticed some weight gain. I have palmoplantar pustulosis psoriasis and within 2 weeks my hands got better. However, I notice that the day before my injection my hands start to act up again. After my shot my hands get better. Enbrel has given me my hands back. I can show them to the world and not feel like I have to hide them. I'm able to write and work and not be in that much pain. F 39 7 weeks
50 MG 1X W
12/9/2010
Email
 1  Rheumatoid Arthritis Enbrel worked very well for my aching joints and fatigue due to RA. No problems with injections at all. I was thinking that I had found the right drug to help me get my activity level back, but unfortunately experienced hot flashes for about a week (thought I was starting menopause), then pain and immobility in right arm (credited that to RA and Fibromyalgia). A month later, I woke up with left side numbness and extreme pain, including my tongue and face. Numbness and pain was accompanied by waves of feelings of pins and needles, muscle weakness, dizziness and blurred vision. Neurologist was worried that Enbrel had caused me to have MS. Brain MRI came back clear, but after three weeks I'm still experiencing blurry vision and numbness and pain, which has diminished except in my feet. I think this is a very effective medicine if you pay attention to the side effects. It's scary to think of the long term effects (hopefully not MS), but it was very effective at controlling RA sympto Pay close attention to any side effects. Read all the enclosed tiny print because reactionis can happen to you, and they can be very serious. MS is a possible side effect. F 44 5 months
50 mg 1X W
12/9/2010
 5  RA Very minor discomfort with the injections. Not using the Sure-click as that IS painful. I also take Methotrexate and have finally weaned myself entirely off of Predizone. My feelings are very much the same as the that of the person leaving the last comment. Just hoping Enbrel continues to work because my life without it was beyond awful. F 58 3 years
50mg 1X W
12/1/2010
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 5  RA No bad side effects After reading some of the comments on here I had to respond. I'm a hospital nurse on a medical unit and have been exposed to H1N1, TB, and many other things. I have never gotton sick even with having less ability to fight infections. There are also many comments about the injections being painful. I don't feel it at all. I don't use the autoject. I allow it to reach room temp, clean an area on my belly with alcohol and Allow it to dry. Then pinch up an area and inject slowly. I have noticed it hurts some if injected to fast which may be a problem with the autojects. I wouldn't be walking if I wasn't taking this drug. F 57 4 years
50mg 1X W
11/27/2010
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 5  RA Occasional mild swelling and itching at injection site. Hives, eczema also an occasional issue. Reluctantly started taking the drug during my worst flare in 10 years of having RA. Almost immediate relief experienced and I am now virtually pain free. The side effects are a minor inconvenience compared to the improvement in my quality of life. M 64 5 months
50mg 1X W
11/21/2010
 5  RA & Psoriasis I have had no side effects It is a wonderful drug and changed my life, it not only cleared up my psoriasis but also my RA had improved 90% before I had to get shots of cortizone in my hand just to function F 70 4 years
30mg 1X W
11/16/2010
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