ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Psoriatic arthritis Fatigue, some headaches, sinus congestion, maybe some weight gain, winter flu has been much more severe. Is very effective for me. Went off Enbrel for a few months and symptoms returned,but went back on and had almost immediate improvement (2 days). M 47 2 years
10/23/2009
 4  RA Feeling a little tired lately. No other side effects. Found out I had RA at 27. After months of complaining about joint pain, fatigue and night sweats my doctor decided to test me. My levels are low but the pain and swelling are severe. I started Enbrel and was quite concerned about the side effects but so far I feel great. I'm not sure I will ever feel comfortable jogging like I used to but at least I am able to do my everyday activities with out pain. F 28 4 months
10/7/2009
 5  RA Little or no side effects! I do have slight brusing at the injection site. However, this last only a day or two. I do get at least two colds a year...which includes sinus. I'm not sure that is due to Enbrel. I have been taking Enbrel since 2005....was diagnosis with RA in 2001 and had severe pain on a daily basis. Enbrel is a Godsend for me...I take one 50mg a week! I now spring out of bed with no pain and climb the 10 steps to my bathroom and get ready for work. Climbing the stairs is my morning exercise...it makes me feel great, as a few years back I had difficulty climbing stairs. I'm able to wear heels again and this does wonders for my Psyche. I do have a question for anyone out there...has anyone experienced canker sore...I have had one for about 1 year now and nothing seems to work at getting rid of it! I should also note that I'm Diabetic and I also take Plaquenil and Levothyrox. Many individuals have written about "being tired" that is a side effect of RA as well....I don't feel I'm tired more than usual. F 47 5 years
10/3/2009
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 2  MCTD After the third of once weekly 50mg injection, I started having flu like symptoms, fever, body aches, nausea etc. Also redness on nose and cheeks. Had a severe allergic reaction to Plaquinil 6 months ago. Decided to try Enbrel. Have not felt any relief although only have taken 3 shots. Don't know if my flu like symptoms were a result of the medication or I actually had the flu. I'm not sure I want to continue. Anyone else with similar experience? I don't think I'll ever feel good again. F 54 3 weeks
9/27/2009
 5  TRAPS (Familial Hibernian Fever) Headaches Fevers disappeared right way, joint pains completely disappeared in a few months and my energy returned in a big way. I still have occasional TRAPS episodes in times of stress, but they are mild and short-lived. Sure-click injections are terribly painful, even at room temperature, but results are worth the pain! F 59 8 months
9/22/2009
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 2  Psoriasis I had no side effects. I received no benefit from this medication; in fact by the time I stopped taking it and resumed my previous treatment, my skin was actually worse. M 45 4 months
9/19/2009
 1  Suspicion of Psoriatic Arthritis Painful burning, itchy rash at injection site. Headache and depression. No energy and feel like crap. This has not caused any symptom relief. I feel worse than ever and just want to sleep. M 50 2 weeks
9/18/2009
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 4  PA I have found that my respiratory infections have taken longer to clear up. Now when I feel like I am getting sick I will stop taking the Enbrel until I am completely better. I have noticed that my weight has increased and that despite continual exercise I feel heavier than I usally am (usually thin). I wonder how this affects bloating -- something I have noticed that I experience more of. M 44 2 years
9/7/2009
 1  psoriatic arthritis I have recently been diagnosed with MS after taking Enbrel for about 2 years. After many MRI scans and doctors visits, it seems that it is very likely that Enbrel brought about the MS. I was once a believer that the benefits outweighed the risks, but that was before being diagnosed with an disease such as MS that may land me in a wheelchair. DO NOT take this drug. F 35 2 years
9/7/2009
 5  RA Not healing as fast from small cuts I was on Remicade for one year and it almost killed me. On that drug I lost 50 pounds, tired all of the time and just did not care about anything. I was rated with the highest RA count you can almost have. With enbrel I am a new person. My weight is back to normal, I can work outside without constant pain. I also have a 7 year old daughter. I missed her early years of not being able to play with her due to the pain. With Enbrel I can do anything. Taking the 50 mg shot once a week is no problem. Never-ever had any pain in the stomach area or the legs. If you have RA please ask your Dr. about this drug. Make sure you have insurance and it is covered as it costs about $1,600 for four shots. M 53 4 years
8/27/2009
 5  Psoriasis Have had no side affects. Have plaque psoriasis and when taking embrel twice a week for the first 3 months, it cleared my psoriasis. Have been taking Enbrel on and off for two years now and it works for me, but then my doctor has taken me off of it because he is concern of possible effect if taking a long period of time. M 48 2 years
8/26/2009
 1  Psorisis I have muscle loss in my thigh from the injections and noticible from across the room. The loss is 6" across my leg and 3+" down toward the knee so a huge area! Two weeks after stopping the drug my condition came back 300X worser than it was before I started using Enbrel. This injection is so very painful. I have undergone every treatment there is for psorisis since 1977-1978 and my opinion this drug is the most dangerous of them all. I have other health issues caused from this drug that I am deaing with now and really scared... F 49 9 months
8/20/2009
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 5  psoriatic arthritis Only a very occasional headache, nothing else I have a mild form of this disease. About 15 years ago I was in to running. I had to stop because of neck pain that I was developing. I endured gradual and increasing neck pain for 10 years. When I started taking Enbrel about 4 years ago, my neck pain stopped within 48 hours of the 1st injection and has not returned! M 49 4 years
8/19/2009
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 4  RA Constant colds, meaning I have to leave off injections until infection has passed (and get antibiotic or cortisone injections from GP, as body can't fight anything any more) Scared about swine flu, given how Enbrel emasculates the immune system. Has anyone read any reports or recommendations in this context? - apart from this fear, I am just so grateful that - after five years of trying unsuccessful alternatives - my Spanish doctors here put me onto Enbrel - and although there is a general prescription charge for other drugs, this is FREE! F 58 4 years
8/18/2009
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 5  ra Started taking Enbrel when it first came out in the early 90's and it was a Godsend! Before taking Enbrel I had very little energy and my fingers were starting to get deformed. I took everything that was available. After taking Enbrel I felt great immediately, less swelling & joint pain, more energy, and I do not have any disfiguration of fingers. Over the years I have developed female yeast infections and yeast in my digestive tract and mouth. I manage these by taking non-milk based acidophilas and staying away from yeast breads and eating very little bread & pasta prodcts. I also take arava along with the Enbrel and this controls my ra. I also take calcium & vitamin D as I am now of the age to get octeoarthritis. I was diagnosed when I was 12 with jra and am now 56 years and hold down a full time job and have lots of energy. I do like the 50mg autoinjector, very convenient. I understand that Enbrel is not for everyone, but it has worked wonders for me. I understand the side effects, and I have minimal brusing/itching at injection site, I inject myself on thighs and back of arms. F 56 15 years
8/16/2009
 4  AS I have experienced no side effects to enbrel.Taking it now for a year.Occasional brusing around injection site which is not the drugs fault. Prior to taking enbrel I couldnt even turn over in bed without severe pain.I was like an old man.My life has been transformed by enbrel and I am not exaggerating.Of course I am concerned about the long term effects but live for today and be happy. M 44 1 years
8/14/2009
 1  RA Much to worried about side affects to take embrel, so here in Australia I am going on a trial drug that is having great results.It doesnt hit your immune system around as much as embrel. So heres hoping. F 46
8/6/2009
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 1  Juvenile Rheumatoid Arthritis Did not have any immediate side affects when I took this. I am 17 now and I now have Leukemia. Enbrel has been highly linked to cancer in kids under 18. I am 17 years old and was diagnosed with APML on March 13th of this year. Do not take this drug for anything ever. F 17 2 years
8/6/2009
 3  RA Brusing at injection site. Stuffy nose and Headache. I use the 50mg sure click's. I also take 25mg of Benedryl 30 min.prior to injection just in case I have a reaction. Take your med. out of the refrigator 30 min. prior to injection. It is somewhat painful but only lasts a few seconds. Still really scared about this medication because of the side effects however really scared about what the future holds with my RA. Dx. 3 years ago with RA. I have been on methotrexiate,folic acid and nexium since dx. I have tried other medications that either sent my liver enzymes sky high or made me so sick I could not function.I still try to work full time and stay as active as possible. I guess if you have doubts about this medication, you have to weigh the risks against the benefits. When you stay so fatigued that your first thought in the morning is just get thru 8 hours of work and you can go home and go back to bed then if Embrel makes it better its a benefit. If when you set down at home to watch a movie and then you try to get up and you are so stiff that you can hardly walk then it is a benefit to try Embrel. If you continually have tendonitis along with joint pain and stiffness then if Embrel works its a benefit. If you are also watching your fingers shift in the wrong direction or you have the edema,redness, and warmth in your joints then if Embel works its a benefit. I am sure you know the risks. I just want to prevent any further damage. I already feel somewhat better and have seen less stiffness with just 2 injections. F 54 2 weeks
7/30/2009
 3  psoraisis/arthritis cost is way to expensive,most people cant afford this, even with help from enbril card. I only was able to take for 3 months. then my ins. (bcbs) stopped helping me with it . I am not happy about that at all. F 48 3 months
7/28/2009
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