ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27


RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Rhuematoid arthritis no side effects SECRET TO PAINFREE INJECTION!!! After a terrible experience with my first (CLICK) injection given by the doctor in his office I was terrified to try this at home. The first one was excrutiatingly painful. The 2nd one given by my husband at home went without a hitch. I let the click pen warm to room temerature for 30 minutes. Took 2 Ibroprophen and 2 Xanax an hour before the injection. I iced the injection site (thigh) with a blue ice pack for a few minutes until it was numb. My husband slightly stretched the skin where he was going to inject. The medication went in within 7-10 seconds with just a very slight (barely noticeable) sting. The only glitch was we waited and waited for that 2nd click.... then realized my husband was still holding down the purple button. After 45 seconds and a confirmed purple reading of the medication indicator we assumed all the med was safely injected. I am the biggest baby in the world when it comes to needles... so this was not easy for me and I fretted and made myself sick over this impending injection. But it was a breeze....even tho the needle was in 3 times longer than it should of been. Of course you would want to check with your doctor regarding the Ibro and Xanax... but it sure helped me! I think stretching the skin helped too. ANYWAY... I felt nothing but a slight sting as the med went in. 2 weeks ago I was on mega doses of Predisone and could barely function. Today I walked the mall with no pain at all and am off F 60 2 weeks
50mg 1X W
5/19/2010
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 5  R A none Awesome drug. M 38 7 months
50mg 1X W
5/16/2010
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 4  Mixed Connective Tissue D/O, RA I started the injections 6 weeks ago, helped with the pain for about 2 weeks but now I feel like I have plateaued with the pain over the last few weeks, has anyone else experienced that? Also experiencing a hot/warm feeling all the time. I always was cold but now I am always hot, but no temp changes. When everyone is saying their cold, I'm saying "are you kidding me, I'm so hot" that is not normal for me. I also noticed that change when I seemed to plateau with the pain. I was on Methotraxate for 24 weeks when my doc decided to add Enbrel so now I take them both once a week. I have no injections site reaction, no infections and no weight gain, but disappointed over pain relief and now the warm/hot body feeling. F 45 6 weeks
50mg 1X W
4/29/2010
 5  Rheumatoid Arthritis a few minutes of itching which began about 3 hours after the injection I'm shocked. Had put off taking this drug due to fear of side effects...had opted for "alternative relief" from RA. Had some success with that but remained in great pain....so finally tried the Enbrel injection. Relief was experienced the very next day!!! (was in big flare situation day first shot was taken) Relief has remained constant. Just took 2nd injection and am very grateful for the improvement. Soooo, so far, so very good! F 58 7 days
50mg 1X W
4/12/2010
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 1  Ankylosing Spondylitis Demyelinating lesions on my brain PLEASE READ IF YOU ARE TAKING ENBREL, THIS REVIEW IS REAL AND IT CAN HAPPEN TO ANYONE! I'm 27 and my life will never be the same after taking Enbrel for only 6 months. 6 months after I had been taking Enbrel with good results I woke up to my face being numb on the right side. A week later I started having double vision and dizziness. I was in a daze and totally non-functioning after awhile. After my face went numb my doctor told me to get off Enbrel and come in for an MRI of my brain. Results showed demyelination on my brain. The Neurologist i see actually teaches at the university med school and did a long study on Enbrels effects on the brain. It took 6 months for all the symptoms to finally get better, not even go away, just ease up. I just came back from Mayo Clinic in Rochester, MN and was given good news that the lesions are finally inactive. It's taken a YEAR for the lesions to become inactive, but now I have a 20% chance of developing Multiple Sclerosis because of this drug and the lasting effects it has had on me. IM ONLY 27 YEARS OLD. For many people Enbrel is a dream medication, but for me it was a total nightmare. I don't want to frighten people, but please just consider this and ask your doctor if you could develop something like this. I will always have lesions on my brain even though I won't touch Enbrel ever again. F 27 6 months
1X W
4/9/2010
 4  AS Tiredness Didn't have any rashes or skin irritations as others describe. Before I was taking 2 pills of Indomethacin a day just to prevent intense pain. Now, I just take an injection once a week and feel great and able to do all the things I did before. However, tiredness is definitely an issue. M 19 7 months
50 1X W
4/7/2010
 3  severe psoriasis No noticeable side effects in 5 mo. The SureClick is more painful than the one with Humira though! I'm pretty sure the Enbrel is helping with the arthritis. Hard to tell unless I go off it and see if the pain is worse than it is when I'm on it. My skin has all but cleared except for the pink areas where the psoriasis was the worst. It is such a relief, but now that I'm waiting to see why I have enlarged lymph nodes, I'm wondering if it's worth it. Had an abdominal CT scan to find out why one leg has been swelling and results show enlarged lymph nodes (1.6 mil). Doctor ordered blood tests which I did today and will wait for results, but I'm a bit worried. I'm in an awkward situation in that I don't have insurance and have not been seen by a rhuemy, only a dermatologist and a free clinic. I get the medication from the Encourage Foundation, which I'm grateful for, but I don't have a "team" to work together and help figure out the best course for me to take. I've done some research and found out that enlarged lymph nodes can be from infection but I'm wondering what kind of infection could I have? If the blood tests come back with lymphoma, I guess I've cooked my goose by taking the Enbrel. It took me 4 years of suffering with the psoriasis and the PA before I decided to try Humira--that cleared me within 2 mo., but then stopped working and when the derm suggested taking the shots every 10 days instead of 14, I started spotting and had to get a uterine biopsy which turned out good. Of course I wouldn't go back on the Humira. I didn't do anything for about 4 mo. until it got so bad again that I decided to try Enbrel. Don't know what's next. Not going to take any more shots until I get the results of the blood test. F 62
50 mg 1X day
4/3/2010
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Patient History
 4  RA Stuffy nose, headache, sore throat, constant clearing of my throat. Welt at injection site. 3 lb weight gain in 5 weeks even with increased cardio. My face feels hot and itchy. But my joint pain is decreased by 75%. I feel almost normal regarding my joints. Just have hoarse voice and sore throat always. I was on Humira for 6 months it worked at first then failed F 45 5 weeks
50mg 1X W
4/2/2010
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 1  RA Headaches, dizziness, nose bleed, night sweats, chills, stomach pain, redness at the injection site, rashes, bruising, trouble with breathing, numbness in the hands, nerve damage in the left hand and arm. It helped me with RA but the side effects are dangerous. OT I have developed stomach pain, CT was all ok. Doctors cant figure it out and its getting worse. Has anyone else has same problem with Enbrel? M 61 3 years
50 mg 1X W
3/27/2010
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 3  psoriatic arthritis / psoriasis none really, except perhaps weight gain. have just noticed lung congestion that I cannot explain and will talk to doc about it soon. helped with psoriatic arthritis but not psoriasis M 48 6 months
50 mg 1X W
3/24/2010
 5  Psoriatic Arthritis I was fairly crippled in the morning before I started Enbrel. I now have a normal life, very active, but still have some joint pain in my hands. I recently had a toenail removed (thick psoriasis nail) and had to stop Enbrel because of repeated infections and anti-biotics during the healing process. I have stopped taking enbrel for almost three weeks and have started feeling very run down but no added joint pain yet. It has been a blessing - I have traveled to Europe twice, I roller blade 3 times a week, work out with weights, and going hiking in the mountains. M 57 7 years
50 mg 1X W
3/16/2010
 1  CRNC Juvenile Rheumatoid Arthritis After my FIRST use of Enbrel, I noticed I was feeling extremely fatigued and nauseous for the following days, not to mention the painful, massive welts it left on my thigh (injection site). I could hardly sit up in the mornings without puking from a sour stomach. These side effects continued for as long as I used Enbrel and I was tested negative for several other diseases. Please, DO NOT use this medication with a cronic diagnosis of any illness, it did not help me or the other patients I had known at all. Also, I discovered there was a high risk of Leukemia(and other closely related cancers). Instead of using this medicine, I suggest Orencia. Do yourself a favor, look into Orencia, it started working the first month of treatment, it has no side effects so far and is not painful (besides when they insert a small tube into your vein for the medicine to pass through.) F 12 17 months
2X W
3/14/2010
 4  Psoriatic Arthritis and Psoriasis 1 day after injection, felt extremely tired and achy-flu like symptoms. Slight headache. Two days later, woke with dry cough. Seems to have lasted for a few hours and now quieted down. Extemely nervous about being on this drug. Will take it for a while as the pain and swelling in my knees made it most difficult to walk. Neck pain quieted down as well. Have tried sulfasalazine and methotrexate but couldn't tolerate due to nausea and mouth sores. Going to see a specialist for antibiotic therapy in about a month. WOuld like to try that as I hear there are far less side effects. Not sure I will continue with Enbrel. F 54 3 days
50MG 1X W
3/11/2010
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 5  rheumatoid arthritis occasional spots on trunk of body Enbrel has transformed by life. I was in severe pain, now this has been considerably reduced. F 53 4 years
50mg 1X W
3/5/2010
 3  r a lupus headache and chest pain not much improvement yet F 55 3 weeks
50 1X W
3/5/2010
 2  RHUEMATOID ARTHRITIS 30 MINUTES INTO MY SECOND SURE CLICK INJECTION , BROKE OUT IN AN ITCHY RASH ON MY ARMS AND SHOULDERS , SHOT IS EXTREMELY PAINFUL, ALOT OF ITCHING AND SWELLING AT INJECTION SITE , ALSO , EXTREMELY TIRED AND IRRITABLE, F 50 2 months
50 MG 1X W
3/5/2010
 5  ankylosing spodilitus Tiredness, headaches and a weird rash under by right cheek which has spread...sure it is something to do with enbrel it has given me my life back! F 31 3 months
15mg 1X W
2/20/2010
 5  RA As far as I am concerned I have had no side effects. Oh I get bloody noses but that is when the air is dry, or I get numbness, but that is because I use the coumputer mouse too much. I get a cold once a year, but I did before Enbrel, so nothing new there. It has been the best thing and has kept my joints from degenerating and has allowed me to continue working. I am almost 61 and came down with RA during menopause, so about 13-15 years ago. Every day I can walk or work and I thank Enbrel for that. F 61 8 years
50mg 1X W
2/12/2010
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 5  RA SEEMS TO MAKE MY SINUSUS DRAIN ON MY FIRST TWO INJECTION DAYS I WAS DIAGNOSED 6 MONTHS AGO... IT CAME ON STRONG...COMPLETELY MISERABLE... NEEDED HELP FROM MY KIDS TO GET SHOES AND SOCKS ON IN THE MORNING FOR THE PAST 6 MONTHS... I HAVE ONLY TAKEN 2 INJECTIONS.. I FEEL SO MUCH BETTER IT IS AMAZING...LETS HOPE IT CONTINUES!!!! M 42 2 weeks
50 MG 1X W
2/11/2010
 4  AS Very sleepy a day or so after injection, but fine after that. Recently noticing that my extremities go to sleep quickly after minutes of sitting or just putting my arm on the back of the couch (weird) not sure if related to drug or not. Keeping up with flu shots has kept flu and colds away. This has greatly improved my quality of life, over the last year and a half. I pray it continues to work as well as it does. M 37 1.5 years
50mg 1X W
2/9/2010
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