ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Plaque Psoriasis Outbreak of guttate psoriasis in the last three months. Have stopped injecting Enbrel but still dealing with the same psoriais which my derm says is not an unusual side effect after using Enbrel for this length of time. Not sure which is worse, the plaque or guttate psoriasis. Enbrel worked quite well until this episode took place. Plaque psoriasis has not worsened since stopping Enbrel, only the guttate. M 67 5 years
8/20/2008
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 5  Rheumatoid Arthritis Injection burns badly (50 mg auto-injector), Weight loss, and insomnia This is a true miracle medicine. I can't believe how much better I feel and it has only been 3 weeks. The injections are so painful I cry before, during, and after but its a small price to pay for this kind of pain relief. F 33 3 weeks
8/15/2008
 5  psoratic arthritis So far no virtually no side effects. I sleep more, but since I was having trouble sleeping, this has not been a problem. I had arthritis in my hands so bad that in the mornings I had to run hot water over them to get them moving. With Enbrel the problem has disappeared. 64 3 months
8/14/2008
 3  RA for 10 years Painful injection,rash,itching lasting for 3-5 days on third injection-feelings of anxiousness(out of sorts)so not me,headaches, painful stomach cramping and a retention of fuild in the legs and stomach,little energy. I took Methotrexate injection for 8 years.I now take a combination of Methotrexate and Enbrel. I would appreciate a comment if anyone has experienced the stomach pain and fluid retention that in consistent and does not decrease. The Enbrel appears to keep the RA at a distance. F 58 6 weeks
8/14/2008
 5  Psoriasis I've been on Enbrel two separate occasions. The first time, I did it 2 times a week for 3 months and the psoriasis was vitually gone. Now I'm doing it only once a week. Both times I've noticed that I keep pulling pieces of skin from my mouth. I have no idea why this happens when I'm on the drug and have not found anyone else with this problem. Just wonder if anyone else has had this problem. I just hope the drug doesn't hurt me in the long run. M 29
8/13/2008
 4  Psoriasis Injection site irritation and burning as injected. Occasional bruising. Initially the dose was every 4 days. It took 6 months before an improvement was seen. Very slow. After the first year the dose was reduced to every 5 days. Continue to see improvements after 2 1/2 years. Using topical creams much less these days. Feet are really the only part where the psoriasis is difficult to treat. F 52 2 years
8/13/2008
 5  Rhuematoid Arthritis I'm wondering if going into deep depression causing attempted suicides could be a possible side effect because this has happened to me and doctors can't see why. I also get bruising on the injection site and I get headaches alot and never used to. Other than that Enbrel has been fantastic! F 15 4 years
8/11/2008
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 5  Psoriatic Arthritis Extreme fatigue, need to sleep longer, nausea, weight gain Works great on the flare ups. Very few since beginning treatment. Very expensive - unavailable without good insurance M 46 6 months
7/29/2008
 5  Psoriatic Arthritis Tired, sleepy, lathargic at times. I have been rotating arms in my once a week shot - I stopped shooting in the leg. I have never had an injection site rash or swelling. Pain is totally gone. Miracle drug, take a shot and your pain goes away! Just had a small amount of psorisis on my forehead and behind my ears - those didn't clear up with the shot but I put stuff on it. M 36 2 years
7/26/2008
 4  Psoriasis Slight pain and swelling around the injection area; tiredness; slight weight-gain I have been self-administering Enbrel since January 2008 ... whilst this no miracle cure for psoriasis, it is keeping it at bay - enough for me to be able to wear short-sleeved shirts when the weather gets better M 46 7 months
7/20/2008
 3  Adult Onset Stills Major Fatigue. Depression (according to my wife). Gained 31 lbs. in three months. I started Enbrel and immediately began an exercise regimen of walking 3.5 miles/day and working out 3 times a week with a trainer. In spite of this, and not much change in my diet, I gained 31 lbs. I sleep 9-12 hrs at night and nap for 1-3 hours at least 5 days a week. The drug has kept my flare ups of severe fevers/joint pain at bay but I feel that they are about to come on but stop just short of doing so. Quality of life is better without the flare ups but the fatigue, weight gain and almost sick feeling is the consequence. M 51 4 months
6/27/2008
 5  RA Weight gain Great drug. Almost full relief of RA symptoms after first injection. Can't seem to figure out the weight gain. I'm exercising more, eating less, and I have now gained 15 pounds. Go figure. Some other message boards also report this finding. M 38 6 months
6/10/2008
 3  ankylosing spondylitis Fatigue, increased allergies Enbrel has increased my endurance & mobility while decreasing pain & inflammation. I use the autoinjector, which is painful but worth it. F 43 11 months
6/5/2008
 4  Rheumatoid Arthritis Easy injections. Slight clouding over top of left eye. Some foot and finger swelling. I started enbrel four or five weeks ago. Overall, I am feeling better and am not too concerned about the side effects. However, I noticed a slight dark patch at the top of my (left) visual field some days ago. Today, my right foot was so swollen and painful I couldn't walk. Without talking to my doctor, I'm not sure if these are side effects or not. I'm still taking Sulfasalazine daily and Diclofenac as necessary - today it was. M 51 5 weeks
6/3/2008
 5  Juvenile Rheumatoid Arthritis (JRA) I have been one of the lucky few who has been virtually side effect free. I have occassional injection site reactions (maybe 1 out of every 10). They are just itchy for a few days, and I barely notice them. Otherwise, I believe that Enbrel has caused a lupus like red rash on my face (tested negative for lupus). Not painful at all, responds to topical steroids for the self conscious. Biggest problem is that if you get any serious infection, you probably will have to get off the Enbrel until it goes away. Its in times like those that you really appreciate how much the medicine is doing for you I was on methotrexate and extremely high doses of NSAIDS before getting the opportunity to try enbrel. My doctor encouraged it, and I was fortunate enough to have an insurance willing to pay the massive costs. It is EXPENSIVE. Very EXPENSIVE. Might be less than some other options, but my insurance company is shelling out $1,500+/month. If other things have failed for you, please consider talking to your doctor about this kind of treatment. It has changed my life in so many ways and allows me to do things(walking almost pain free, jogging, even running with a little work in the gym first to strengthen up those muscles). M 24 10 years
5/22/2008
 3  RA for 25 years painful injection, slight bruising, staff infection I took enbrel for 2 years with very good results until I got a staff infection which settled in 2 of my thoractic vertebrae. Spent 10 days in the hospital, the first few days in severe pain,many rounds of drugs, blood tests, MRI's. Then spent 2 months wearing a brace from my waist to my chin, and a continuous antibiotic IV for 2 months. We believe the staff infection started from a small cut on my finger, but not sure. I already had degenerative disc disease before all this, now I am on social security disability.Enbrel worked great while it worked but suppressing your immune system has it's risks. I'll never take it again. Now taking methotrexate and celebrex. M 59 2 years
5/6/2008
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 3  Psoriatic Arthritis Dizziness and tiredness that have subsided. Large hive-like swelling at injection site. Persistent pain around injection sites. Swelling of feet and hands. I've just taken my third injection. After #1 I was dizzy and very tired, but noticed improvement in my spine w/i a few days. Had a great week. Injection #2 provided very little relief, which was upsetting. At the moment it's hard to say whether or not this drug will help me, but because of ulcerative bowel disease, I cannot take MXT or NSAIDS. Took Prednisone for years, but had to discontinue due to pulmonary/cardiac side effects. I've avoided the biologics for years, mainly because I've been terrified of the side effects. Now that I've made the jump, I'm hoping it works and doesn't kill me in the process. We all deserve to live a pain-free life. F 44 3 weeks
4/28/2008
 4  R A i get a rash at the injection site that is very itchy. it lasts for a few days and it leaves a darker mark in the area where i had the rash the rash is not fun but i feel so much better using this product. my body feels so much better i can do all the things i was having trouble with before this medicine. F 29 2.5 months
4/22/2008
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 5  RA Possibly low immune but live in an area where sinus trouble is very common. No other negative effects. Have had RA since 17yrs. Enbrel has been great for me...no more flare ups since beginning treatment. Felt relief with 1 week. Also, HIGHLY recommend RA people to follow a High-protein, low carb diet and exercise. My RA is VERY affected by my diet...currently down to one 25mg shot a week in the abdomen area (no bruising & no pain) F 44 5 years
4/20/2008
 5  Psoriatic Arthritis I have been taking Enbrel for almost 4 years and have had no adverse reactions. I have been dealing with Psoriatic Arthritis for almost 20 years. Most of that time I was treated with varying doses of methotrexate and extensive use of ibuprofen. The methotrexate seemed to lose it's effectiveness in 2004 and I experienced some severe arthritic symptoms of swelling, stiffness and aching joints. My doctor prescribed Enbrel and it has worked so well, I frequently forget to give myself my shots. It is working for me. I play golf about 4 times per week usually walking with my 3 wheel push cart. I also play and coach soccer. without Enbrel none of this would be possible. M 56 4 years
4/18/2008

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