ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  RA Sometimes after the injection I get joint and muscle ache and sometimes pain in my back and neck. It is very inconsistent. F 50 5 years
2X W
11/16/2010
 1  Psoriasis I experienced symtoms of MS. Horrible headaches and mirgraines. I had double vision for a week and spent Christmas on my back recovering from a spinal tap. Cleared my psoriasis but not worth the side effects, be careful. M 42 1 years
1X day
11/13/2010
 3  psoriasis I feel a little tired the day after. Can't come to giving my self the shot so I go 2 my doc every 4 days to have them put it in my arm. I am a very healthy active person. I am concerned with the side effects that I read about. I have in on about 30% of my body. It jumped from 3%-30 in 1 year. I prefer natural hurbs to cure my psoriasis but have found that nothing works. Anyone have advice for me? Thanks F 29 2 weeks
50mg 2X W
11/10/2010
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 1  Psoriasis Got Multiple Sclerosis from this drug Worked very well on my Psoriasis but as I have learned it can have some evil side effects M 49 4 years
1X W
11/9/2010
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 3  rheumatoid arthritis Occassional discomfort at injection. Let injector warm and ice injection site for a while. Should reduce pain. Caught RA early. Can't see a lot of difference. Virtually no side effects. However, RA does not appear to have progressed much since first diagnosis. Don't see a lot of difference if I miss an injection. M 59 4 years
1X W
10/27/2010
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 4  R.A. Just a couple so far. My sinus problems are worse. Have a little bit of a sore throat. Not sleeping very well. Am also on Rifampin with this medication It has worked amazingly quick.Before if I did anything to aggravate a joint, the next day it would be getting hot and then swell. Most of my daily soreness is gone and I hope stays that way :) 10 yrs ago I did treatment for Hep-C and was wondering if anyone else with R.A.has also been diagnosed with Hep-C?? I warm the shot up just rolling it in my hand. Not so bad going in. I do have a little redness around the injection site this time, but I didn't use ice this time. Will remember it next time.I use my stomach for injection site, just freeze a little spot, shoot and a little ice after the shot. I push it in pretty slowly also. I will post again if anything else comes up. F 56 3 weeks
1X W
10/26/2010
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 5  RA Enbrel has given me my life back not in so much pain as before I started the drug.How ever I have experince some weight gain as a result of taking the meds. F 38 5 weeks
50mg 1X W
10/16/2010
 3  AS My 16 year old daughter has been diagnosed with AS and the specialist has suggested Enbrel for treatment. ANYONE with ANY feedback for me would be greatly appreciated. Her father and I have done all the research and are terrified of the outcome if not treated with Enbrel. (methotrexate, sulfasalazine, arthrotec not working) We are concerned about some of the serious side effects of Enbrel long term. F 16 0 days
Unknown 1X W
10/12/2010
 4  RA & AS fatigue, especially day after injection Enbrel has allowed me to walk again & use my hands more efficiently. It is amazing & I regret postponing trying it for almost a year. I still have pain in my joints, especially my feet, but my life is more 'normal' now than it has been in years. My wheelchair & rollabout are now stored in the garage rather than the car & I like that a lot. I haven't had any infections or other illnesses at this time, but I am much more aware of the risk of being around people who are ill & the absolute need for good self-care. F 50 6 weeks
50 mg 1X W
10/3/2010
 5  Ankylosing Spondylitus Fatigue (although I think this could be explained by the AS). Had AS since I was 12, didn't get treated for it until 18. Started out taking normal anti-inflammatorys but this did not help at all. I wasn't able to walk anywhere, the pain was intense. After first 2 doses of Enbrel, I could live my life. This is amazing. Yes, I understand this could lead to more problems in the future, but I'd rather have a livable life while I'm still young rather than be tortured everyday. So far absolutely no problems.My pain is about 95% gone and I take an anti-inflammatory every day to prevent bone degradation. M 19 1 years
50 1X W
9/26/2010
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 3  RA I had been taking another drug since May which was helping with joint pain in my knees and ankles, but my wrist pain increased. I also noticed hair loss with this med. My doctor suggested adding Enbrel in August. I have my husband inject the preloaded syringe. The first three weeks I had no injection site reaction, but in the last two weeks the injection site has been red,sore and hard, lasting for almost 5 days. My hair loss has increased considerably. So much so that I asked my doctor if I could stop the previous medication and only take Enbrel, which I did. I have also noticed more sinus drainage thus causing my throat to be sore, and a cough. I've also noticed that cuts take longer to heal. After two weeks of taking Enbrel, my wrist, the last joint that continued to be painful, has gotten so much better. Still concerned about the hair loss but not sure if there is still residual from the previous meds in my body causing this or if it's a side effect of Enbrel. I do not want to go bald. I've only been taking medication for RA for 5 months, so I'm trying not to get discouraged as I know I just have to find the right drug combination for me. I also take prednisone when I have a flair up. F 54 5 weeks
50 mg 1X W
9/24/2010
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 4  psoriasis drowsy the next day I have just started this medicine and i am really hoping it helps. im a little worried about the side effects but it seems to be helping already. F 27 2 weeks
25mg 2X W
9/22/2010
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 4  Rhumetoid Arthritis The only thing that bothers me about this injection is the pain of the actual injection once I click. I don't think I notice any other symptoms apart from weight gain - but that is probably just me and not enbrel. Also, the auto injector is so much more convenient because the majority of the syringe ones were always faulty for me and very frustrting. I was diagnosed with Juvenille Chronic Arthritis when I was 3 years old. Since then I have been on almost every other medication for arthritis but nothing worked long term. I just remember alway getting sick and being prone to infections, and throughout my childhood I pretty much was sore every single day. I was depressed as a child because I couldn't really do anything, participate in sports, go to the shops without using a wheelchair. Even throughout my schooling I couldn't really cope without a wheelchair and that was lowering my self esteem. In 2004 my wonderful doctor introduced enbrel to me and my mother. I didn't want it at first mostly because I was scared, but he guaranteed that it will work , so I gave it a try and it has been the best thing ever for me. I honestly, rely on this drug so much. I noticed a difference as soon as I took it and pretty much can walk now for longer periods. I am proud to say that I am 22 years old, and I haven't used a wheelchair for quite a few years now. I think I am a better and more confident person because of it. There are times where I miss my injection (which I know is really careless of me), and I start to get really bad again. But as soon as I have enbrel I am fine again. I don't think there is a better alternative out there. Not for me anyway. The auto injector is the way to go! F 22 6 years
50mg 1X W
9/21/2010
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 1  Psoriasis Lymphoma, infections Do not take embrel for any reason M 60 2 years
25mg 1X W
9/19/2010
 3  Psoriatic Arthritis Reoccurring infections - lower chest, ear, nose ulcers. Recently noticed bruising appearing from nowhere. Swollen Lymph nodes which then did calm down. Weight gain, tiredness, bowel trouble, migraines, cluster headaches (although there are other factors in a lot of these symptoms) Has basically "cured" the psoriasis part of my disease. Gone from a PASI of approx 60, to having a PASI of >2 since the treatment kicked in. Life changing. No change on the arthritis side unfortunately. Would have given the treatment a 5 had I only had psoriasis. Injection can be sore and I have had big stonking bruises (although not EVERY time) My sister had glandular fever (much to the worry of my doctors with me being on MTX and enbrel) but I didn't catch it. (phew!) If I could make the decision to go on Enbrel again, I'd have no hesistation. Whilst it comes with its side effects (which meds don't??) its worth the life changing experience if you can rid yourself of your psoriasis. F 24 2 years
50mg 1X W
9/5/2010
 5  Ankylosing Spondylitis As time goes on, chronic fatigue syndrome. I do take high dose narcotics in conjunction(7yrs). Enbrel SAVED MY LIFE TOO! Symptoms started when I was 12y/o; diagnosed when I was 27y/o. I was on the threshold of doing something "BAD", then I i finally got the Dx & Enbrel. As previous comments, it only took 1-2days to show effectiveness!! I just can't do anything "real" physical anymore! BUT NOW...I get cellulitis once a yr and have to be hospitalized. My lymphnodes seem to stay swollen on my neck and head at all times, though at different degrees. Any "nick" or cuts don't heal like they used to. I'm scared that I may develop lymphatic cancer! However...I will gladly battle the cancer over the pain that I had been suffering from my AS. M 33 5.5 years
50mg 1X W
8/28/2010
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 5  RA Redness, lump at injection site Wonderful drug. Gave me back my life! F 52 8 weeks
50mg 1X W
8/23/2010
 4  Rheumatoid Arthritis Red welt approx 6" diameter at injection site. Hair dry and thinning. Ecsema starting to sprout on arms, slight cough. I love seeing my symptoms 90% gone, but I worry about taking such a strong drug and what it is doing to my body. There's always a reaction to any med you take. Just have to weigh the risk. F 62 2 months
not sure 1X W
8/19/2010
Email
 3  plaque psoriasis stings at injection site, a general bogged down feeling for a couple days afterwards but not every week. I have had psoriasis since I was 20. I probably have it on 10-15% of my body with the worst being my scalp and finger nails. I notice when my finger nails are really bad and I am in a meeting or socializing in a group people notice my finger nails right away. I know this because they automatically start looking/biting and picking at their nails. I CANT STAND PEOPLE DOING THIS!!!! Enbrel has suppressed elbow, scalp, and knee patches but it completely cleared my finger nails in 4-5 weeks (had to grow out). I love it for this very fact but hate it for what I know it may be able to do to you in the long run. I don't want to die from lymphoma, or never recover from severe influenza. I know if I use this stuff forever this will be the case. I only use it when my nails start getting really bad. I'll do a month on and then quit for 4 months. Seems to be working out alright like this. I also use clobetasol proprianate ( a topical ointment) in conjuction with enbrel on all my elbow, knee, buttocks patches and I can almost get it completely clear for a few weeks before the lack of enbrel use regularly makes it start to come back. M 30 1.5 years
50mg 1X W
8/19/2010
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 2  undifferentiated sponyloarthropathy currently i get at least one bad headache a week. reg headache medicine does not work. i have found the next day after injection i have a very upset stomach mostly in evening. not sure why. I also have severe diareaha about 3 days after the shot. stomach cramps up like a virus or food poisoning. the medicine itself burns badly during injection. Humira didn't hurt like this. so far i have not found relief. but i need to give it more time. i am so young to be on full ssi. but all the meds, i can't function in a day to day job. i have undifferentiated spondyloarthropathy with enthesopathy. i tested positive for HLAB27 (gentic marker) anyone else? i feel so alone with my diagnosis. it's like tendonitis thru my whole body. i can feel for everyone who's left their information. i'm lost and really hope enbrel is the answer given more time. i don't want to try another injection.. humira worked,i leveled off (bruising only real side effect) and then they upped it to weekly, felt creepy crawly... yuck F 36 4 weeks
30mg 1X W
8/18/2010
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