ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  AS So far I have no side effects I felt improvement from first week I had taken enbrel , now I feel almost 80% of my pain is gone M 66 7 months
50 mg 1X W
3/20/2012
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 4  PA, possible fibromialgia sore, red raised injection sites. injected cold, warm, room temp. no diff. some times severe colds, upper chest,pneumnia conjuction with other med shots, flu or h1n1 shots. worse when others around me are sick pick up different stains of bugs, not severe. i have been off enbrel one time for over a year due to it stopped working. first injection i felt great after 3 days, for 3 years. stopped it, felt like i was run over, went back on and a few weeks later felt ok. agian joints upper and lower and muscles flare up and i am just exhuasted some days.still am after 5 years, benidrel was stated to me of 20ml before injection to help with inflammation of injections.. M 49 5 years
50ml 1X W
2/19/2012
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 4  Ankylosing Spondylitis Big Red Bump, Bruising, The meds. Burn when being injected I was diagnosed with AS and Chondrolysis about a year ago I was so stiff in my hip I could barely Walk. I missed a lot of school and I was miserable. Now enbrel has worked wonders. I am actually running a 5k in June! F 14 1 years
50 MG 1X W
2/8/2012
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 5  Psoriasis and Psoriatic arthritis Virtually no side effects since starting Enbrel PA has improved dramatically. I cannot imagine going back to the way I felt prior to Enbrel. I was taking Arava and had some success but my Rheumatologist thought I could do better with Enbrel and he was certainly right. However, it has not helped my psorasis at all. I have experienced none of the side effects others have mentioned. This has been a life changing drug F 63 7 years
25 mg 2X W
2/1/2012
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 4  Severe Psoriasis Occasional burning during injection, fatigue the day after (although this went away after I took it for a while). I was about 75% covered with Psoriasis and Enbrel cleared it to about 5%. Effectiveness started to wane after about a year, but still kept psoriasis at bay. Try only to inject it into your thighs. I tried injecting it into my lower abdomen as demonstrated on the diagram and I found it wasn't as effective. Also, make sure you get the bloodwork done to check your liver because Enbrel can damage it. Mine is fine thus far, but I'm keeping an eye on it. Otherwise, great drug! After my skin was cleared I felt like a new person and my confidence went way up. :) F 23 1 years
50mg 2X W
1/29/2012
 5  rheumatoid arthritis none this is a wonderful drug after 1 injection I was able to close my hands almost fully without pain, my feet were not as swollen, I could also almost bend my toes and my ankles didn't feel as though there was bone on bone rubbing together, this is an amazing drug and highly reommend it drug and recommend it to anyone who thinks that there is no hope F 54 2 times
50 mg 1X W
1/17/2012
 4  reactive Arthritis I have an injection site reaction, very large area of redness, firmness, warmth and itching. tried heat and ice without much relief, Also more frequent headaches and nausea all my pain went away 2 days after the first shot!!! F 34 3 weeks
50 mg 1X W
12/22/2011
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 4  ankylosing spondylitis Occasional numbness in leg (whichever one I inject it into). Had injection site reaction until switched from auto-injector to pre-filled syringes. I'm still young 20s, and this drug has helped me regain much mobility and energy. Though, I am worried about the long term health issues with this being a newer medication. M 22 1.5 years
50 MG 1X W
12/14/2011
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 5  Ankylosing Spondylitis M 35
50mg 1X day
12/12/2011
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Patient History
 5  Psoratic Arthritis and psorisis From time to time a get a fever the day after my dosage for 1 day. I have been taking enbrel for 6 years and I am not showing any signs of PA. My psorisis cleared up almost immediately, however after 6 years some has come back, however, not the levels I had before. M 45 6 years
50mg 1X W
12/10/2011
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 5  Psoratic Arthritis Auto-Injector=injection side reaction BUT did not have with pre-filled syringe. Found injection less burning feeling if not quite room temp. Leave out for only 4-5 minutes then inject. Has really really helped me. However, dr said most his patients only have 50mg one time week. But on the 4th day, I start feeling pain again, in hands and feet and fatigue. So he increased it to 50 mg twice a week. F 28 1 years
50 mg 2X W
12/7/2011
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 5  RA Occasional injection site redness and pain. Intermittent hives. Maybe coincidental but 7 surgeries in the last 12 months for basal cell and squamous cell skin cancer. Intermittent dry skin. I will take all of the side effects rather than change from Enbrel. It has been a life changing drug allowing me to live a full and active life. RA had started to attack my lungs and this drug stopped it dead in its tracks. M 65 18 months
50mg 1X W
11/29/2011
 5  RA None I am a performing violinist and almost went on disability 10 years ago. Enbrel has literally saved my career allowing me to perform several hundred concerts and record a number of CD's. It has been a total life saver for me! M 64 9 years
25 MG 2X W
11/14/2011
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 5  Moderate psoriasis Not really a side effect but I noticed its better to do the injection at night, instead of the morning, or I'd feel a little drowsy during the day. Injecting at night has taken care of that. I was scared to death to get on this medication because of the reported risks and side effects. I finally got to the point that I couldn't take it anymore and saw my dermatologist. I couldn't be happier that I did! I cleared almost 100% within 2-3 weeks of starting this medication. It has literally been a miracle for me! The sure-click auto injectors are really easy to use. The medicine burns while it is going in, for 10-15 seconds, then it's done & the pain goes away. I highly recommend this medication if you're fed up with your psoriasis. F 28 5 months
50mg 1X W
11/4/2011
 3  AS None I'm a young mum with two kids aged 3 and 16 month, I'm in alot of pain with AS and cannot take anything else due to long term liver and kidney problems so my doc has suggested this. I'm not sure what to do as I'm absolutely terrified of the side effects but also want to live my life and enjoy my kids! Anyone with any advice would be much appreciated F 32 0 days
30 1X day
10/31/2011
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Patient History
 5  RMA and severe psoriasis None I use the 50 miligram sureclick. I leave it out for 10 to 15 minutes to get too room temp and alternate injections in my thighs. I agree with one of the previous posters about taking supplements and exercising while on this medication. I worry about long term side affects but it's cleared psoriasis that covered about 40% of my body. I had plaque psoriasis on the soles of my feet and it was at times painful and itchy. I take milk thistle to help support liver function. You need to keep a close eye on your bloodwork. I seriously think the doctors get incentives for prescribing this but it's made a big difference in my life and I dread the thought of how bad it will be if I discontinue the Enbrel. Some patients do not need to take it weekly so you might want to review that with your doctor. I seem to be best off taking it weekly. M 54 2 years
1X W
10/25/2011
 5  Ankylosing Spondylitis NO side effects I was in an extreme amount of pain from the inflammation in my joints as well as aches throughout my body. After Enbrel, it just about all went quickly. Recently, i've had a constant stiff neck and shoulders which is from my condition. Still, I'll take that after what I had previously been through. I've rcently had an insurance screwup and haven't been able to refill for the past 3 weeks. Strangely enough I havent had any relapse since going temporarily off it. I'm wondering if anyone else has had the same experience M 50 4 months
50mg 1X W
10/24/2011
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 4  RA Horrible itchy rash for 1 year, 'white matter on the brain, lost periods of time, vision abnormalities. I am going through test to determine if I have MS. Enbrel was great until it side effects hit me like a bomb. F 59 10 years
50mg 1X W
10/12/2011
 3   I take Enbrel for Psoriasis, which is about 80% clear. I was able to somewhat enjoy my summer for once since my skin was clearer than it had been in 30 years. but....my body hurts all over. Arms, hands, legs and feet keep "falling asleep" (pins and needles feeling). This has been going on for over 2 weeks. I have an all over uncomfortable feeling in my body that keeps me awake at night. I am very nervous about this drug. One doctor pushes the drug and another said I am poisoning my body. I am trying to weigh the benefits vs the risks and I'm not sure clear skin is going to win over having my life and my health. Has anyone stopped the drug for a while and then continued it again? Or has anyone spaced the injections out over more time vs. once weekly? F 44 5 months
50 MG 1X W
9/29/2011
 3  RA 1st and 2nd weeks had no side effects, 3rd time hot red knot appeared at injection site. 4 week the spot was twice the size of the first time. so thats why I am reading and checkin this out. I starting taking Embril 4 weeks ago, after manys years of different meds from plaquenil, methotexate, leuflumide, and alot of predisone. All of which worked for a while or I was allergic to. I do feel much better in the last four weeks and have alot of hope my pain will continue to lessen and side effects will get less. I am a L&D nurse and need my body to be at its best. I have not been able to exercise, have gained alot of weight from using prednisone. I want my life back. I have read all the comments and will try some things to ease the injection site problems, but I have to say if the medication works as well for me as for most of the people I have read, I CAN DEAL WITH THAT PAIN at the injection site. will post as I go. F 52 4 weeks
50 1X W
9/25/2011
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