ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  RA I have noticed irritability. Also fatigue is a major factor. I don't seem to last long with anything too physical. I am concerned about my depression and the frustration. It interferes with my workday and relationships. Aside from my problems with this drug, I became a whole, functioning human being again. My RA was rampant in my hands and feet. Therefore walking or working with my hands became miserable. The risks are worth it at this time. F 56 1 years
1/16/2008
 5  Psoriatic Arthritis small bump at inject site sometimes(like the Enbrel is just sitting there) miracle. when I can't use it due to severe cold or infection, the old extreme pain returns. Vicodin helps a bit but limits my ability to drive/work. God Bless scientists/researchers for their discovery M 49 6 years
12/14/2007
 4  RA NONE SO FAR I JUST DID MY FIRST ENBREL INJECTION ON 12/12/07 AND I CAN ALREADY SAY THE PAIN IN MY HANDS ARE MUCH LESS SEVERE. I HAVE BEEN DIAGNOSED WITH RA IN MY EARLY 20'S AND HAD A TOTAL KNEE REPLACEMENT BY AGE 36. I AM CURRENTLY STILL ON MY OTHER MEDS WITH THE ENBREL UNTIL I SEE DR IN JANUARY. I TAKE PLAQUENIL 200 MG 2X A DAY,AZULFIDINE 500MG 2X A DAY AND 20MG METNOTREXATE WEEKLY. MY DOCTOR SAID YOU SHOULD WAIT TO LET ALCOHOLYOU WIPE ON SITE FOR INJECTION TO DRY BEFORE DOING YOUR INJECTION AND THIS WILL ALLEVIATE BURNING. M 48
12/14/2007
 5  Psoriatic Arthritis and Psoriosis Only one side effect, I am hungry all time! F 48 5 days
12/5/2007
 5  Rheumatoid Arthritis My mouth was filled with a strong medicinal taste 15 minutes after I took my first Sureclick injection in my thigh, and I felt a sharp kind of contraction in the area of my heart, all of which startled and scared me. I've not had that reaction since. I've also noticed a faint slightly bitter medicinal odor that emanates from my flesh. This medicine helped me (advanced RA) from the very first injection, so it was apparent how powerful it was. It really eliminates pain and swelling in an incredible way. Injecting is difficult for me, though Sureclicks make it as easy as possible. I've only had 7 injections, and twice I stopped for 2 weeks as I had to undergo dental work, and I wanted the antibiotics that I must take for protection of my knee implants to be working. Not sure about the efficacy of antibiotics when on Enbrel. I sometimes think that weekly injections might be too much. Could go a bit longer between shots. This is strong medicine, but something like a miracle, barring the side effects which, upon reading, make one say a prayer. F 62 2 days
12/1/2007
 5  PA First few times I took injections I got a severe headache. Since first taking enbrel I have been diagnoised with migraines for which I now take a migraine pill relpax which takes care of my headaches, maybe unrelated. These headaches are not very often anymore. This drug has been a life saver for me. Any side effects are minimal as to the pain relief I have from taking this WONDER DRUG! I go on & off this drug several times a year because of minor infections. After being off for a month I noticed relief in days of restarting enbrel. Thank GOD for this medication. M 43 8 years
11/29/2007
 3  RA Two areas of fungus on hips (not at injection point) and a horribly itchy rash on my back and scalp. Currently giving myself 50mg shot weekly and taking 5mg Prednisone daily. I cannot take Methotrexate because it drives my liver enzymes high. Enbrel seemed to work at first, but I have developed hand deformity and cannot open things. One day, I could not start my car. Plus, I've had to stop Enbrel from time to time because of infection F 62 2 years
11/29/2007
 5  ra inj site rash itching burning bruising 1st 5 yrs couldnt dress brush hair teeth barely walk 6 mo before enbrel tried celebrex methotrexate prednisone and other drugs first hardley made a dent enbrel helped after few weeks has worked great for 9 yrs do notice not as effective now back on small prednisone dose and advil everyday went off for 1 mo right back to cripple definetly worth the risk F 42 9 years
11/28/2007
 5  Psoriatic Arthritis Possibly a slight difficulty in recovering from sinus infections. In the big picture, none that are of any consequence. Enbrel changed my life. PA was the wake up call in 2002-2203 for me to smell the roses, and Enbrel allows me to wander the rose garden. I'm 49. For years, all I did was work, work work, and not take care of myself. I was overweight, drank and smoked, did not excercise, etc. etc. In early 2003, my dr. told me that I was headed for life in a wheel chair if something had not controlled my PA. In late 2002/early 2003, PA hit me hard, preceded from Jan 02 by psoriasis. The first Rheumatologist in 11/02 missed the diagnosis--even though my feet and knees were killing me, an my left hand would "freeze closed." The second dr. figured it out just by looking and talking to me--he was one of those who got Enbrel first approved for PA. In 6 weeks, I went from being barely able to walk due to foot and knee pain (or, for that matter roll over in bed due to back pain, or open my hands due to hand and finger pain) to ablsolutely no pain at all. And while I still had the psoriasis--an M 49 70 months
11/28/2007
 3  ankylosing spondylitis I have experienced flu like side effects and sinisitis I would like to know from others who experienced flu like side effects if these side effects eventually went away ? M 40 3 weeks
11/28/2007
 4  PA I had a couple of times my injection site "bubble up" and i could barely get the last of the 50 mg into my subQ skin layer. when i took my first shot of enbrel i could feel it overnight that it took away the pain and some of the swelling. i was actually able to clean the kitchen for the first time in a year.It took the docters about a year and a half to figure out what was actually wrong with me.after a couple of months of not knowing what i was dealing with i was in severe pain and could barely get around.this drug has helped me take control over my life again, the only thing is that it has not really helped my psoriasis i still have some on my scalp and behind the ear. F 19 3 years
11/15/2007
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 5  Ankylosing Spondylitis Flu-like, little weakness. I have been on the 50mg sureclick autoinjector for 2 weeks and I feel great. I am almost pain free. For the people with injection site pain, did you try to warm it up to room temp.? I do not even feel it going into my thigh. M 35 14 days
11/11/2007
 5  Rheumatiod Arthritis Some injection site itching. Perhaps increased severity of sinus infections. Took 6 weeks to take effect, and when it did, it relieved 90% of symptoms. It is not a miracle drug..still get tired easily, and do not have former strength, but before Enbrel, I couldn't even turn the key to start my truck, and had difficulty in slipping a credit card in and out of a gas pump. I can now resume controlling a shopping cart with one hand, so it has worked well, even with time-outs for back and hip surgery. Previously, I had a terrible reaction to methotrexate [and it did work for 2 months from the original dose, but on trying it again, it worked not at all]. Enbrel let me get off Prednisone entirely. I hope it keeps working. Medicare part D helps a bunch, but I go through the donut hole in late February to mid March M 77 2 years
10/28/2007
 3  RA Possibly extreme irritability, frustration, depression. Bruising at injection site and other locations where I've bumped a desk. Fatigue seems to be mitigated somewhat. Only had 4 injections to date. Want to know if anyone else has been short tempered, quick to snap at anyone? Itching and tingling like an anxious feeling. No real issues except the irritable personality. I want to continue with hope of relief from the RA. I have much pain and swelling, so I'm going for it. F 48 4 weeks
10/16/2007
 5  Psoriatic Arthritis Injection sight reactions...fairly large, 3 inch red itchy whelps, last 4 days or so. Ability to live like I don't have arthritis. No morning pain wake-up or flu-like symptoms through the day. No aching knees and hands..a miracle drug. F 29 4 months
10/7/2007
 5  RA Have had no side effects Works very well. Couldn't believe how fast it started working. Got off of it for 3-4 weeks because of sinus infection and the difference was amazing. After I got back on it, I could tell a big improvement almost immediately. M 67 8 months
10/1/2007
 5  Early moderate rheumatoid arthritis None. Got relief after a few days. Have had no RA symptoms since starting Enbrel. M 48 2 months
9/23/2007
 5  RA Injection site reaction for a few months Enbrel has been wonderful for me. Try icing the site first and taking Tagamet or benedryl (at nite) to minimize site reactions. Enbrel relieved my stiffness and gelling after the first week. I also take steriods and sometimes NSAIDs. F 9 months
9/21/2007
 5  RA Not really any side effects Does anyone out there take enbrel and coumadin at the same time. No one can give me a straight answer concerning these two drugs and I am in so much pain right now because I am afraid to take both of them together F 64 5 days
9/20/2007
 3  RA headache with nausia and sweating, usually several days after missing a dose, or after vigourous exercise. At first only occasional, but gradually these sick head aches became more frequent. The headaches were so unpleasant that I stopped taking Enbrel for several months. Then RA flared up badly, and I started Enbrel again. I have a sick headache as I type this, and am vowing never to take Enbrel again. Headache and sick feeling is really unpleasant. Enbrel does work VERY well for my RA, however. F 52 2 years
9/10/2007

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