ENBREL Reviews (ETANERCEPT)

Average Rating: 3.7 (533 Ratings)

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 TUMOR NECROSIS FACTOR-ALPHA INHIBITORS

 Type: Rx Drug

  

ENBREL  (ETANERCEPT):  This medication is used alone or in combination with an immunosuppressant (such as methotrexate) to treat certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, and ankylosing spondylitis). Some brands of this medication are also used to treat a skin condition called psoriasis. These conditions are caused by an overactive immune system (autoimmune disease). The immune system attacks the body's own healthy cells, causing inflammation in the joints and skin. Etanercept controls your body's defensive response by blocking the action of a certain natural substance (TNF) that is used by the immune system. Treatment decreases redness, itching and scaly patches in psoriasis as well as the pain, swelling and stiffness of joints in arthritis. This medication can stop the progression of disease and joint damage, resulting in improved daily functioning and quality of life. This medication treats but does not cure autoimmune diseases. Symptoms usually return within 1 month of stopping the medication.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ENBRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Psoriatic Arthritis I was involved in a clinical trial at a major NYC hospital. After three months I experienced accute neurological numbness in both arms and my right thigh. A known side effect. When I started the trial the doctor measured my coverage at 13% after three months it was 12%. Since stopping the drug because of the side effects they have gone away completely. My psoriasis however is now consumming 75% of my skin. A disaster. I would not call this a miracle drug for me. I have had PA since I was 27 (now 54) and have not changed my health habits before, during or after the trial, it has never been out of control like this. I would stay away at all costs. And I was getting it for free. Is there a class action suit brewing out there, if so I'm in. M 54 4 months
6/12/2009
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 4  Ankylosing Spondylitis Sore throat! I'm constantly hoarse recently. Has anyone else experienced this? Kinda weird. It is a wonder drug. I was taking Difene anti-inflammatorys and they were destroying my insides, but honestly, since i started Enbrel 18 months ago i am back playing team contact sports! Unreal. Although i still have my flare ups trust me! And i do have to take the odd anti inflamm, but it's worth it. 100%. F 30 18 months
6/10/2009
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 4  Ankylosing spondylitis Injection site reactions severe red welt and burning for several days on 50 mg trigger injector. Switched to 50 mg prefilled and it made a world of difference!! It was causing spider veins in my legs so I always inject in the belly.( have notice most of the Weight gain in my stomach... 10-15 pounds in the year:( 4 upper respiratory infections this year, never had one in my life Has definitely helped me.. less stiff in morning by 80%.Right now it is worth it because I could not walk a year ago. I have stomach issues and headaches that are frustrating but keep a close watch on symptoms and side effects with my rheumatologist. M 42 15 months
5/30/2009
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 4  rhuematoid artritis I would have a runny nose most of the time,and tired every day I find enbrel 50mg and metrotrexate have given me a good quality of life ive been taken enbrel now for 2 years. F 40 2 years
5/28/2009
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 4  Juvenile Rheumatoid Arthritis I take it once every other week instead of once weekly. I haven't noticed any side effects. I am taking birth control and have noticed moderate mood changes, but I can't be sure this is from the birth control or from the enbrel. I am going to ask my doctor. F 29 2 years
5/13/2009
 4  psoriasis runny nose, cough, colds, tired. M 39 1 months
5/13/2009
 4  RA Decrease in appetite, rash on my arms I have only taken 3 shots and I can not tell that big of a difference yet with my hands being drawn but am looking forward to the results. F 21 3 weeks
5/11/2009
 4  RA Painful injection Like many people, I switched from a powder and diluent you had to mix yourself to a prefilled 50mg syringe. I find the prefilled injection very painful to administer, whereas the old method hardly hurt at all. I have been told that the pain is caused by a preservative in the mixture. I wish I could go back to the old method. I didn't mind having to mix it myself and it didn't take long. I can understand that the drug company were probable trying to make life easier, but if it's not broken..... don't fix it. F 27 4 years
5/5/2009
 5  RA No side effects enbrel gave me my life back. Within days I could make a fist, joint swelling slowly disappeared, joint pain almost all gone, only a few flare ups in 3.5 years. I was able to get on with my life. F 56 3.5 years
5/4/2009
 3  Psoriasis I am having abnormal bruising on my thighs from me scratching. I have had strep throat once. My psoriasis broke out again after having strep throat and I have not had the results I did from the first 2 mths of treatments. I do 50mg injections 2 x week. F 28 3 months
5/3/2009
 5  RA Injection site reaction; intense pain with 50 mg injection. Switched to twice weekly 25 mg injections and no problems thereafter. A wonder drug for me. However, it lost effectiveness after about 4 years. F 39 4 years
4/28/2009
 3  Rheumatoid arthritis After 2 months on Enbrel I had no more pain. However, I had to stop taking it shortly after due to a perforated colon with abscess. Reading various articles seems to prove that this is not an uncommon side effect. My doctor wants me to start taking it again, but I have decided not to as I do not want to run the risk of another intestinal problem. M 66 2 months
4/28/2009
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 3  psoriases Face developed a rash/glow, cant shift it since, been perscribed alsorts of creams but nothing effective yet. only got this since starting on enbrel 6 weeks ago no real improvement in my p. its just got smoother, and the face rash is driving me mad. maybe i am expecting too much too quick, how long have others with p taken to notive any improvement?? did any1 else get face rash?? M 37 6 weeks
4/26/2009
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 5  psoriasis weight gain, some irritabilityand lethargy, more blurred vision, slow healing, varicose veins seem to be developing Has reduced psoriasis by 98%, but the drug is associated with blood disease, and my varicose veins have multiplied quite a bit since I started taking it. M 60 18 months
4/22/2009
 3  Psorasis Headache, Fatigue, slight weight gain, and just a general feeling of unwell one to two days after injection. Lately have noticed chest tightness and some pains. Am having more blookwork done to find out if there could be another cause for some of my symptoms. I've been on enbrel twice now... first time for about seven to eight months and stopped taking because I couldn't stop getting sick and couldn't get over my illness, have been back on it again now for almost three months... I've noticed it hasn't cleared my skin as well as the first time, hope this is temporary. F 33
4/13/2009
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 5  psoriasis severe headache, itching and hive at injection site I thought I'd be on creams and ointments the rest of my life. Enbrel is wonderful! All my psoriasis has disappeared except for a few small flare-ups mostly when I get stressed about something. My scalp is psoriasis-free! YIPEE! Now no worries about wearing a black shirt:) The headache has subsided nothing a motrin or tylenol can't handle. I'm even thinking if I lost some weight I could actually wear a bikini now. M 38 3 months
4/11/2009
 4  Psoriasis Abdominal bloat leading to weight gain and uncomfort, even though I eat right and exercise; using Sure-Click version: usually blood at every injection; slight pain during-little itch afterward. Seem a little lethargic, not sure if it is stress or the medicine. This has been a miracle drug for me, the psoriasis covers about 75% percent of my body. Within one month, there was significant improvement. I have been taking the drug for two 1/2 months now, and my skin is amazingly clear. It has improved my self-confidence and esteem. As long as the side effects don't hurt more than the drug, I will keep taking it! F 42 75 days
4/8/2009
 5  RA, PA Injection site reactions; just gave myself my 3rd injection. Itchy, painful welts showed up 5 days after second injection; the next day on the third. Benadryl and Desonide cream seems to help. Other than that, none. Been living with RA for ten years. This is the best drug so far. More energy, regulated sleep, no pain, which makes all the difference in my mood. I've taken just about everything out there. Now just taking Leflunomide and the Enbrel. Hope this lasts! F 36 3 weeks
4/4/2009
 4  Rhuematiod & Osteo Arthritis One 50mg pre-filled syringe of Enbrel weekly for RA. Very little pain when warmed up for at least 30 minutes, inserted into a fatty area (stomach seems better than thigh) at a 45 degree angle, and pushed in very slowly. If it's any where near a muscle the needle is in way too far; it only needs to be under the skin. No weight gain or loss and no other side effects noticed. I was only sick with a "flu" type virus for two days this year and no colds or chest issues. No RA flare-ups so it must be working !! Osteo join pain somewhat reduced. I was off Enbrel and Methotrexate for a total of 6 weeks for full knee replacement surgery. I had no negative impact from being off of the drugs was healing well post surgery. I went back on both drugs on the advice of my Rheumatologist and now my healing seems to be going backward. Has anyone experienced this type of problem? F 57 7 days
3/31/2009
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 1  psoriasis lymphoma, congestive heart failure For me this was a miracle drug. And now it has changed my health and well being for life. F 47 5 years
3/31/2009
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